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sulfasalazine and Hyperplasia

sulfasalazine has been researched along with Hyperplasia in 6 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
" Lentinan decreased the number of tumours, inflammatory cell infiltration, atypical hyperplasia and nuclear atypia in azoxymethane/DSS-induced CAC model."7.91Therapeutic effects of lentinan on inflammatory bowel disease and colitis-associated cancer. ( Chen, S; Jing, X; Li, M; Liu, H; Liu, Y; Sun, B; Sun, T; Tian, Y; Wang, H; Yang, C; Zhang, Q; Zhao, J; Zhao, Y; Zong, S, 2019)
" Lentinan decreased the number of tumours, inflammatory cell infiltration, atypical hyperplasia and nuclear atypia in azoxymethane/DSS-induced CAC model."3.91Therapeutic effects of lentinan on inflammatory bowel disease and colitis-associated cancer. ( Chen, S; Jing, X; Li, M; Liu, H; Liu, Y; Sun, B; Sun, T; Tian, Y; Wang, H; Yang, C; Zhang, Q; Zhao, J; Zhao, Y; Zong, S, 2019)
"Susalimod was extensively excreted via the bile in all animal species, > or =90%, mainly as non-conjugated parent compound."1.30Extensive biliary excretion of the sulfasalazine analogue, susalimod, but different concentrations in the bile duct in various animal species correlating to species-specific hepatobiliary toxicity. ( Andersson, S; Gunnarsson, K; Odell, ML; Påhlman, I; Wilén, M, 1999)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, Y1
Zhao, J1
Zhao, Y1
Zong, S1
Tian, Y1
Chen, S1
Li, M1
Liu, H1
Zhang, Q1
Jing, X1
Sun, B1
Wang, H1
Sun, T1
Yang, C1
Kim, JY1
Cho, HJ1
Sir, JJ1
Kim, BK1
Hur, J1
Youn, SW1
Yang, HM1
Jun, SI1
Park, KW1
Hwang, SJ1
Kwon, YW1
Lee, HY1
Kang, HJ1
Oh, BH1
Park, YB1
Kim, HS1
Gallais, V1
Grange, F1
De Bandt, M1
Crickx, B1
Belaïch, S1
Spodaryk, M1
Mrukowicz, J1
Stopyrowa, J1
Czupryna, A1
Kowalska-Duplaga, K1
Fyderek, K1
Miezynski, W1
Påhlman, I1
Andersson, S1
Gunnarsson, K1
Odell, ML1
Wilén, M1
Lafeuillade, A1
Bolla, G1
Horschowski, N1
Fossat, C1
David, M1
Salvator, V1
Schiano, A1

Other Studies

6 other studies available for sulfasalazine and Hyperplasia

ArticleYear
Therapeutic effects of lentinan on inflammatory bowel disease and colitis-associated cancer.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Azoxymethane; Carcinoembryonic Antigen;

2019
Sulfasalazine induces haem oxygenase-1 via ROS-dependent Nrf2 signalling, leading to control of neointimal hyperplasia.
    Cardiovascular research, 2009, Jun-01, Volume: 82, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Carotid Artery Diseases;

2009
[Salazosulfapyridine-induced eruption. Pustular erythroderma and pseudo-lymphomatous syndrome: 2 cases].
    Annales de dermatologie et de venereologie, 1994, Volume: 121, Issue:1

    Topics: Adult; Dermatitis, Exfoliative; Diagnosis, Differential; Drug Eruptions; Eosinophilia; Female; Human

1994
Severe intestinal nodular lymphoid hyperplasia in an infant.
    Journal of pediatric gastroenterology and nutrition, 1995, Volume: 21, Issue:4

    Topics: Barium Sulfate; Colon; Duodenum; Enema; Enteral Nutrition; Humans; Hyperplasia; Infant; Intestinal P

1995
Extensive biliary excretion of the sulfasalazine analogue, susalimod, but different concentrations in the bile duct in various animal species correlating to species-specific hepatobiliary toxicity.
    Pharmacology & toxicology, 1999, Volume: 85, Issue:3

    Topics: Animals; Area Under Curve; Benzoates; Bile; Bile Ducts; Bilirubin; Dogs; Dose-Response Relationship,

1999
[Lymphadenopathy due to sulfasalazine in rheumatoid polyarthritis].
    Presse medicale (Paris, France : 1983), 1989, Oct-21, Volume: 18, Issue:34

    Topics: Aged; Arthritis, Rheumatoid; Female; Humans; Hyperplasia; Lymphatic Diseases; Sulfasalazine

1989