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sulfasalazine and Hemolysis

sulfasalazine has been researched along with Hemolysis in 11 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.

Research Excerpts

ExcerptRelevanceReference
"In an attempt to estimate the frequency of folate deficiency and haemolysis in a group of 25 outpatients with arthritis treated with sulphasalazine (SASP), haematological measurements, including plasma total homocysteine (tHcy) which is a sensitive marker of folate deficiency, serum folate (S-folate), erythrocyte (RBC) folate, S-cobalamin and routine indices of haemolysis were performed."7.69Folate and homocysteine status and haemolysis in patients treated with sulphasalazine for arthritis. ( Ekelund, S; Krogh Jensen, M; Svendsen, L, 1996)
"In an attempt to estimate the frequency of folate deficiency and haemolysis in a group of 25 outpatients with arthritis treated with sulphasalazine (SASP), haematological measurements, including plasma total homocysteine (tHcy) which is a sensitive marker of folate deficiency, serum folate (S-folate), erythrocyte (RBC) folate, S-cobalamin and routine indices of haemolysis were performed."3.69Folate and homocysteine status and haemolysis in patients treated with sulphasalazine for arthritis. ( Ekelund, S; Krogh Jensen, M; Svendsen, L, 1996)
"Hemolytic anemia is a well-recognized complication of sulfasalazine treatment."1.26Hemolytic anemia in patients receiving sulfasalazine. ( Ali, MA; Castelli, M; Goodacre, RL; Hamilton, JD; Seaton, T; Vanderlinden, B, 1978)
"In 36 unselected patients with ulcerative colitis or Crohn's disease taking 4."1.26Hemolysis during salicylazosulfapyridine therapy. ( van Elferen, LW; van Hees, PA; van Rossum, JM; van Tongeren, JH, 1978)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's4 (36.36)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Sahm, J1
de Groot, K1
Schreiber, J1
BADE, HJ1
Tack, CJ2
Lutterman, JA1
Wetzels, JF1
Krogh Jensen, M1
Ekelund, S1
Svendsen, L1
Baadenhuijsen, H1
Seuren-Jacobs, HE1
Jansen, AP1
Goodacre, RL1
Ali, MA1
Vanderlinden, B1
Hamilton, JD1
Castelli, M1
Seaton, T1
van Hees, PA1
van Elferen, LW1
van Rossum, JM1
van Tongeren, JH1
Wijnands, MJ1
Nuver-Zwart, IH1
van Riel, PL1
van 't Hof, MA1
Gribnau, FW1
van De Putte, LB1
Kater, F1
Cohen, SM1
Rosenthal, DS1
Karp, PJ1

Trials

1 trial available for sulfasalazine and Hemolysis

ArticleYear
Hemolysis during low-dose sulfasalazine treatment in rheumatoid arthritis patients.
    Scandinavian journal of rheumatology, 1991, Volume: 20, Issue:1

    Topics: Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Haptoglobins; Hemoglobins; Hemolysis; Hemop

1991

Other Studies

10 other studies available for sulfasalazine and Hemolysis

ArticleYear
Sulfasalazine-induced mononucleosis-like-illness and haemolysis.
    Scandinavian journal of rheumatology, 2021, Volume: 50, Issue:1

    Topics: Adult; Antirheumatic Agents; Drug Hypersensitivity Syndrome; Epstein-Barr Virus Infections; Female;

2021
[HEMOLYTIC ANEMIA WITH THE FORMATION OF HEINZ BODIES AFTER SALAZOSULFAPYRIDINE THERAPY].
    Nederlands tijdschrift voor geneeskunde, 1963, Dec-14, Volume: 107

    Topics: Anemia; Anemia, Hemolytic; Erythrocytes; Heinz Bodies; Hemolysis; Pathology; Sulfanilamide; Sulfanil

1963
[Problems in the interpretation of the percentage of glycosylated hemoglobin in patients with diabetes mellitus].
    Nederlands tijdschrift voor geneeskunde, 1995, Nov-11, Volume: 139, Issue:45

    Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Anemia, Iron-Deficiency; Chromatography, High Pressure L

1995
Decreased HbA1c levels due to sulfonamide-induced hemolysis in two IDDM patients.
    Diabetes care, 1996, Volume: 19, Issue:7

    Topics: Adult; Anti-Inflammatory Agents; Child; Diabetes Mellitus, Type 1; Female; Hemoglobin A; Hemolysis;

1996
Folate and homocysteine status and haemolysis in patients treated with sulphasalazine for arthritis.
    Scandinavian journal of clinical and laboratory investigation, 1996, Volume: 56, Issue:5

    Topics: Adolescent; Adult; Aged; Arthritis; Arthritis, Rheumatoid; Colitis, Ulcerative; Erythrocytes; Female

1996
Continuous-flow determination of serum inorganic phosphate with a single reagent--the vanadomolybdate method re-evaluated.
    Clinical chemistry, 1977, Volume: 23, Issue:7

    Topics: Acids; Anticoagulants; Bilirubin; Chlorpromazine; Evaluation Studies as Topic; Hemolysis; Humans; Me

1977
Hemolytic anemia in patients receiving sulfasalazine.
    Digestion, 1978, Volume: 17, Issue:6

    Topics: Anemia, Hemolytic; Colitis, Ulcerative; Crohn Disease; Electrophoresis, Starch Gel; Heinz Bodies; He

1978
Hemolysis during salicylazosulfapyridine therapy.
    The American journal of gastroenterology, 1978, Volume: 70, Issue:5

    Topics: Adolescent; Adult; Aged; Anemia, Hemolytic; Colitis, Ulcerative; Crohn Disease; Female; Hemolysis; H

1978
[Hemolysis, formation of Heinz bodies and of methemoglobin under therapy with Azulfidine (author's transl)].
    Medizinische Klinik, 1974, Mar-15, Volume: 69, Issue:11

    Topics: Adult; Colitis, Ulcerative; Cyanosis; Diarrhea; Erythrocytes; Female; Headache; Heinz Bodies; Hemato

1974
Ulcerative colitis and erythrocyte G6PD deficiency. Salicylazosulfapyridine-provoked hemolysis.
    JAMA, 1968, Aug-12, Volume: 205, Issue:7

    Topics: Adult; Anemia, Hemolytic; Colitis, Ulcerative; Glucosephosphate Dehydrogenase Deficiency; Hemolysis;

1968