Page last updated: 2024-11-04

sulfasalazine and Granuloma

sulfasalazine has been researched along with Granuloma in 14 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Granuloma: A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.

Research Excerpts

ExcerptRelevanceReference
"A severe systemic reaction to sulfasalazine developed in a 21-year old female with rheumatoid arthritis characterized by eosinophilia, granulomatous enteritis and myelotoxicity, cholestatic hepatitis, and seizures."7.71Is it Crohn's disease? A severe systemic granulomatous reaction to sulfasalazine in patient with rheumatoid arthritis. ( Fontana, RJ; Greenson, J; Haftel, HM; Quallich, LG, 2001)
"A severe systemic reaction to sulfasalazine developed in a 21-year old female with rheumatoid arthritis characterized by eosinophilia, granulomatous enteritis and myelotoxicity, cholestatic hepatitis, and seizures."3.71Is it Crohn's disease? A severe systemic granulomatous reaction to sulfasalazine in patient with rheumatoid arthritis. ( Fontana, RJ; Greenson, J; Haftel, HM; Quallich, LG, 2001)
"In summary: the Crohn's disease cannot be cured by surgical means."1.29[The role of conservative surgery in Crohn disease: practical results obtained from a case]. ( Csonka, C; Ludmány, E; Nagy, L, 1993)
"We report a patient with ulcerative colitis in whom hepatic granulomatosis was associated with salicylazosulfapyridine (Azulfidine)."1.26Granulomatous hepatitis associated with salicylazosulfapyridine therapy. ( Callen, JP; Soderstrom, RM, 1978)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19907 (50.00)18.7374
1990's3 (21.43)18.2507
2000's1 (7.14)29.6817
2010's2 (14.29)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Yang, YW1
Lehrer, MD1
Mangold, AR1
Yiannias, JA1
Nelson, SA1
Pittelkow, MR1
Mohyuddin, GR1
Sultan, F1
Zhang, K1
Khaleeq, G1
Abdou, A1
Zaouri, H1
El Moussaoui, N1
Senouci, K1
Hassam, B1
Ismaili, N1
Namias, A1
Bhalotra, R1
Donowitz, M1
Al-Hadidi, S1
Khatib, G1
Chhatwal, P1
Khatib, R1
Csonka, C1
Ludmány, E1
Nagy, L1
Clayden, AM1
Bleys, CM1
Jones, SF1
Savage, NW1
Aldred, MJ1
Quallich, LG1
Greenson, J1
Haftel, HM1
Fontana, RJ1
Smith, MS1
Barker, JD1
Callen, JP1
Soderstrom, RM1
Bargon, J1
Rust, M1
Kardos, P1
Schneider, M1
Meier-Sydow, J1
McPoland, PR1
Moss, RL1
Rafoth, RJ1
Di Silvio, TV1
Bartlett, EF1

Reviews

1 review available for sulfasalazine and Granuloma

ArticleYear
Sulfasalazine induced lung toxicity masquerading as sarcoidosis--case report and review of the literature.
    Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2013, Nov-25, Volume: 30, Issue:3

    Topics: Arthritis, Rheumatoid; Colitis, Ulcerative; Granuloma; Humans; Sarcoidosis; Sulfasalazine

2013

Other Studies

13 other studies available for sulfasalazine and Granuloma

ArticleYear
Treatment of granuloma annulare and related granulomatous diseases with sulphasalazine: a series of 16 cases.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2021, Volume: 35, Issue:1

    Topics: Aged; Aged, 80 and over; Dermatitis; Female; Granuloma; Granuloma Annulare; Granuloma, Giant Cell; H

2021
[Crohn's disease: Vulvar edema and swelling].
    Presse medicale (Paris, France : 1983), 2016, Volume: 45, Issue:3

    Topics: Adrenal Cortex Hormones; Anus Diseases; Crohn Disease; Drug Combinations; Drug Substitution; Edema;

2016
Reversible sulfasalazine-induced granulomatous hepatitis.
    Journal of clinical gastroenterology, 1981, Volume: 3, Issue:2

    Topics: Adult; Chemical and Drug Induced Liver Injury; Granuloma; Hepatitis; Humans; Liver Diseases; Male; S

1981
Granulomatous arthritis in Crohn's disease.
    Arthritis and rheumatism, 1984, Volume: 27, Issue:9

    Topics: Adolescent; Arthritis; Crohn Disease; Female; Granuloma; Humans; Prednisone; Sulfasalazine; Synovial

1984
[The role of conservative surgery in Crohn disease: practical results obtained from a case].
    Orvosi hetilap, 1993, Dec-05, Volume: 134, Issue:49

    Topics: Adult; Colectomy; Crohn Disease; Drug Combinations; Glucosamine; Granuloma; Humans; Ileostomy; Ileum

1993
Orofacial granulomatosis: a diagnostic problem for the unwary and a management dilemma. Case reports.
    Australian dental journal, 1997, Volume: 42, Issue:4

    Topics: Anti-Inflammatory Agents; Cheilitis; Child; Chronic Disease; Diagnosis, Differential; Face; Female;

1997
Is it Crohn's disease? A severe systemic granulomatous reaction to sulfasalazine in patient with rheumatoid arthritis.
    BMC gastroenterology, 2001, Volume: 1

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Crohn Di

2001
Granulomatous ileocolitis preceded by three years of pauciarticular arthritis.
    The American journal of gastroenterology, 1978, Volume: 69, Issue:3 Pt 1

    Topics: Arthritis, Juvenile; Aspirin; Child; Crohn Disease; Granuloma; Humans; Male; Prednisone; Sulfasalazi

1978
Granulomatous hepatitis associated with salicylazosulfapyridine therapy.
    Southern medical journal, 1978, Volume: 71, Issue:9

    Topics: Adult; Chemical and Drug Induced Liver Injury; Colitis, Ulcerative; Female; Granuloma; Humans; Sulfa

1978
[Salazosulfapyridine-induced eosinophilic pneumonia with pulmonary and cutaneous epithelioid cell granulomatosis in Sjögren syndrome].
    Pneumologie (Stuttgart, Germany), 1990, Volume: 44, Issue:4

    Topics: Aged; Female; Granuloma; Humans; Pulmonary Eosinophilia; Sjogren's Syndrome; Skin Diseases; Sulfasal

1990
Cutaneous Crohn's disease and progressive vitiligo.
    Journal of the American Academy of Dermatology, 1988, Volume: 19, Issue:2 Pt 2

    Topics: Adult; Colonic Diseases; Crohn Disease; Female; Granuloma; Humans; Remission, Spontaneous; Skin Dise

1988
Systemic granulomatous reaction to salicylazosulfapyridine (Azulfidine) in a patient with Crohn's disease.
    The American journal of digestive diseases, 1974, Volume: 19, Issue:5

    Topics: Adult; Biopsy; Chemical and Drug Induced Liver Injury; Crohn Disease; Diagnosis, Differential; Femal

1974
Malacoplakia of the colon.
    Archives of pathology, 1971, Volume: 92, Issue:3

    Topics: Adolescent; Anti-Bacterial Agents; Cephalothin; Colonic Diseases; Doxycycline; Escherichia coli Infe

1971