sulfasalazine has been researched along with Graft vs Host Disease in 3 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Graft vs Host Disease: The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One patient was a 14-year-old male with acute myelogenous leukemia who received SCT from a related HLA-identical donor." | 1.32 | Experience with the use of salazosulfapyridine for intractable diarrhea after hematopoietic stem cell transplantation. ( Ando, A; Isokawa, S; Miyata, H; Moriguchi, N, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takatsuka, H | 2 |
| Iwasaki, T | 1 |
| Okamoto, T | 2 |
| Kakishita, E | 2 |
| Moriguchi, N | 1 |
| Isokawa, S | 1 |
| Ando, A | 1 |
| Miyata, H | 1 |
| Okada, M | 1 |
| Yamada, S | 2 |
| Itoh, T | 1 |
| Mori, A | 1 |
| Saheki, K | 1 |
| Wada, H | 1 |
| Tamura A, Y | 1 |
| Fujimori, Y | 1 |
| Takemoto, Y | 1 |
1 review available for sulfasalazine and Graft vs Host Disease
| Article | Year |
|---|---|
Intestinal graft-versus-host disease: mechanisms and management.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; | 2003 |
2 other studies available for sulfasalazine and Graft vs Host Disease
| Article | Year |
|---|---|
Experience with the use of salazosulfapyridine for intractable diarrhea after hematopoietic stem cell transplantation.
Topics: Adolescent; Diarrhea; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immuno | 2004 |
Successful treatment of chronic graft-versus-host disease with sulfasalazine in allogeneic bone marrow transplantation.
Topics: Adjuvants, Immunologic; Adult; Bone Marrow Transplantation; Chronic Disease; Combined Modality Thera | 1999 |