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sulfasalazine and Glomerulosclerosis, Focal Segmental

sulfasalazine has been researched along with Glomerulosclerosis, Focal Segmental in 1 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Glomerulosclerosis, Focal Segmental: A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.

Research Excerpts

ExcerptRelevanceReference
"A 59-year-old woman with ulcerative colitis developed red eyes, pleural effusion, eosinophilia and urinary abnormalities after restarting of sulphasalazine treatment."1.35Proteinase 3-antineutrophil cytoplasmic antibody-(PR3-ANCA) positive necrotizing glomerulonephritis after restarting sulphasalazine treatment. ( Aoyama, R; Imai, H; Kitagawa, W; Miura, N; Nishikawa, K; Yamada, H, 2009)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miura, N1
Aoyama, R1
Kitagawa, W1
Yamada, H1
Nishikawa, K1
Imai, H1

Other Studies

1 other study available for sulfasalazine and Glomerulosclerosis, Focal Segmental

ArticleYear
Proteinase 3-antineutrophil cytoplasmic antibody-(PR3-ANCA) positive necrotizing glomerulonephritis after restarting sulphasalazine treatment.
    Clinical nephrology, 2009, Volume: 71, Issue:1

    Topics: Antibodies, Antineutrophil Cytoplasmic; Colitis, Ulcerative; Female; Gastrointestinal Agents; Glomer

2009