sulfasalazine has been researched along with Fetal Death in 5 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Fetal Death: Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the safety of corticosteroids and sulfasalazine in pregnancy associated with inflammatory bowel disease, we reviewed the outcome of 531 such pregnancies in a national survey." | 7.66 | Pregnancy in inflammatory bowel disease: effect of sulfasalazine and corticosteroids on fetal outcome. ( Ahmed, SW; Dobbins, WO; Korelitz, BI; Mogadam, M, 1981) |
| " Chronic ulcerative colitis had been treated with oral prednisone and sulfasalazine until the second month of pregnancy and then with prednisone only." | 3.67 | Intrauterine aplastic anemia and fetal hydrops: a case report. ( Becroft, DM; Zwi, LJ, 1986) |
| "To determine the safety of corticosteroids and sulfasalazine in pregnancy associated with inflammatory bowel disease, we reviewed the outcome of 531 such pregnancies in a national survey." | 3.66 | Pregnancy in inflammatory bowel disease: effect of sulfasalazine and corticosteroids on fetal outcome. ( Ahmed, SW; Dobbins, WO; Korelitz, BI; Mogadam, M, 1981) |
| "Of patients with Crohn's disease whose pregnancies resulted in fetal complications, active IBD was present in 62." | 1.27 | The influence of inflammatory bowel disease and its treatment on pregnancy and fetal outcome. ( Baiocco, PJ; Korelitz, BI, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mogadam, M | 1 |
| Dobbins, WO | 1 |
| Korelitz, BI | 2 |
| Ahmed, SW | 1 |
| Baiocco, PJ | 1 |
| Xiong, JM | 1 |
| Liang, B | 1 |
| Mo, YQ | 1 |
| Chen, ZH | 1 |
| Zwi, LJ | 1 |
| Becroft, DM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Sulfasalazine on CRH Levels in Pregnant Women With a History of Pre-Term Birth: A Randomized Controlled Trial[NCT05703425] | Phase 2 | 50 participants (Anticipated) | Interventional | 2023-03-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for sulfasalazine and Fetal Death
| Article | Year |
|---|---|
Pregnancy in inflammatory bowel disease: effect of sulfasalazine and corticosteroids on fetal outcome.
Topics: Adrenal Cortex Hormones; Colitis, Ulcerative; Crohn Disease; Female; Fetal Death; Fetus; Humans; Inf | 1981 |
The influence of inflammatory bowel disease and its treatment on pregnancy and fetal outcome.
Topics: Abortion, Spontaneous; Colitis, Ulcerative; Congenital Abnormalities; Crohn Disease; Female; Fetal D | 1984 |
Reproductive toxicology. Salicylazosulfapyridine.
Topics: Animals; Birth Weight; Body Weight; Dose-Response Relationship, Drug; Female; Fetal Death; Gastroint | 1997 |
[Teratologic studies of methyl 5-aminosalicylate and salicylazopyridine].
Topics: Abnormalities, Drug-Induced; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; | 1992 |
Intrauterine aplastic anemia and fetal hydrops: a case report.
Topics: Abruptio Placentae; Adult; Anemia, Aplastic; Colitis, Ulcerative; Edema; Female; Fetal Death; Humans | 1986 |