sulfasalazine has been researched along with Familial Felty Syndrome in 2 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Felty's syndrome is characterized by neutropenia, splenomegaly, and leg ulcers in patients with rheumatoid arthritis." | 1.32 | Salazosulfapyridine-induced remission of Felty's syndrome along with significant reduction in neutrophil-bound immunoglobulin G. ( Ishikawa, K; Kaneko, Y; Kuroiwa, T; Nojima, Y; Sugiura, T; Tamura, S; Tsukada, Y; Ueki, K, 2003) |
| "Four with Felty's syndrome developed a further fall in the total WBC associated with thrombocytopenia in two." | 1.28 | Sulphasalazine in rheumatoid arthritis: haematological problems and changes in haematological indices associated with therapy. ( Bacon, PA; Farr, M; Scott, DG; Symmons, DP; Tunn, EJ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishikawa, K | 1 |
| Tsukada, Y | 1 |
| Tamura, S | 1 |
| Kaneko, Y | 1 |
| Kuroiwa, T | 1 |
| Ueki, K | 1 |
| Sugiura, T | 1 |
| Nojima, Y | 1 |
| Farr, M | 1 |
| Tunn, EJ | 1 |
| Symmons, DP | 1 |
| Scott, DG | 1 |
| Bacon, PA | 1 |
2 other studies available for sulfasalazine and Familial Felty Syndrome
| Article | Year |
|---|---|
Salazosulfapyridine-induced remission of Felty's syndrome along with significant reduction in neutrophil-bound immunoglobulin G.
Topics: Aged; Antirheumatic Agents; Felty Syndrome; Female; Flow Cytometry; Humans; Immunoglobulin G; Neutro | 2003 |
Sulphasalazine in rheumatoid arthritis: haematological problems and changes in haematological indices associated with therapy.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Felty Syndrome; Female; Hematologic Diseases; Humans | 1989 |