Page last updated: 2024-11-04

sulfasalazine and Edema

sulfasalazine has been researched along with Edema in 14 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

Research Excerpts

ExcerptRelevanceReference
"), which reduced mortality and pathology (including colon obstruction, ulceration, wall thickness, and myeloperoxidase release) more effectively than the clinically used drug sulfasalazine (100 mg/kg/day p."3.78Antagonism of protease-activated receptor 2 protects against experimental colitis. ( Cotterell, AJ; Do, AT; Fairlie, DP; Liu, L; Lohman, RJ; Suen, J; Vesey, DA, 2012)
" Chronic ulcerative colitis had been treated with oral prednisone and sulfasalazine until the second month of pregnancy and then with prednisone only."3.67Intrauterine aplastic anemia and fetal hydrops: a case report. ( Becroft, DM; Zwi, LJ, 1986)
" The multi-layered enteric polymer coating could potentially protect nanoparticle dissolution at gastric pH and accelerate the dissolution velocity, which would improve the drug bioavailability in the colon."1.42Multi-laminated metal hydroxide nanocontainers for oral-specific delivery for bioavailability improvement and treatment of inflammatory paw edema in mice. ( Deng, JP; Jeng, CC; Kankala, RK; Kankala, S; Kuthati, Y; Lee, CH; Liu, CL; Lue, SI; Shih, HY; Sie, HW; Weng, CF, 2015)
"We diagnosed late onset spondyloarthropathy according to clinic and radiographic findings."1.38Late onset spondyloarthropathy mimicking polymyalgia rheumatica. ( Altındağ, O; Aydeniz, A; Gürsoy, S; Oğüt, E, 2012)
"Metastatic Crohn's disease is a rare inflammatory process that is non-contiguous from the bowel."1.38Metastatic Crohn's disease of the penis: two cases. ( Husain, E; Hussain, F; McClinton, S; Ormerod, A; Vint, R, 2012)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's0 (0.00)18.2507
2000's2 (14.29)29.6817
2010's9 (64.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Junek, R1
Brůnová, B1
Kverka, M1
Panajotová, V1
Jandera, A1
Kuchar, M1
Bishnoi, A1
Banerjee, N1
Saikia, UN1
Parsad, D1
Kankala, RK1
Kuthati, Y1
Sie, HW1
Shih, HY1
Lue, SI1
Kankala, S1
Jeng, CC1
Deng, JP1
Weng, CF1
Liu, CL1
Lee, CH1
Abdou, A1
Zaouri, H1
El Moussaoui, N1
Senouci, K1
Hassam, B1
Ismaili, N1
Suresh, R1
Gupta, S1
Sathananthan, R1
Aydeniz, A1
Altındağ, O1
Oğüt, E1
Gürsoy, S1
Song, IH1
Hermann, KG1
Haibel, H1
Althoff, CE1
Poddubnyy, D1
Listing, J1
Weiss, A1
Freundlich, B1
Rudwaleit, M1
Sieper, J1
Vint, R1
Husain, E1
Hussain, F1
McClinton, S1
Ormerod, A1
Lohman, RJ1
Cotterell, AJ1
Suen, J1
Liu, L1
Do, AT1
Vesey, DA1
Fairlie, DP1
Kita, J1
Tamai, M1
Arima, K1
Kawashiri, SY1
Horai, Y1
Iwamoto, N1
Okada, A1
Koga, T1
Nakashima, Y1
Suzuki, T1
Yamasaki, S1
Nakamura, H1
Origuchi, T1
Ida, H1
Aoyagi, K1
Uetani, M1
Eguchi, K1
Kawakami, A1
Tay, SH1
Lateef, A1
Cheung, PP1
Winney, RJ1
Gilmour, HM1
Matthews, JD1
Zwi, LJ1
Becroft, DM1
Wackers, FJ1
Tytgat, GN1
Vreeken, J1

Trials

1 trial available for sulfasalazine and Edema

ArticleYear
Relationship between active inflammatory lesions in the spine and sacroiliac joints and new development of chronic lesions on whole-body MRI in early axial spondyloarthritis: results of the ESTHER trial at week 48.
    Annals of the rheumatic diseases, 2011, Volume: 70, Issue:7

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Bone Marrow Diseases; Chronic

2011

Other Studies

13 other studies available for sulfasalazine and Edema

ArticleYear
Antileukotrienic N-arylethyl-2-arylacetamides in the treatment of ulcerative colitis.
    European journal of medicinal chemistry, 2007, Volume: 42, Issue:8

    Topics: Acetamides; Animals; Colitis, Ulcerative; Disease Models, Animal; Edema; Hydrophobic and Hydrophilic

2007
An infiltrated vulvar plaque: Metastatic cutaneous Crohn's disease.
    American journal of obstetrics and gynecology, 2019, Volume: 221, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Crohn Disease; Edema; Erythema; Female; Gluco

2019
Multi-laminated metal hydroxide nanocontainers for oral-specific delivery for bioavailability improvement and treatment of inflammatory paw edema in mice.
    Journal of colloid and interface science, 2015, Nov-15, Volume: 458

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Cell Line, Tumor; Drug Ca

2015
[Crohn's disease: Vulvar edema and swelling].
    Presse medicale (Paris, France : 1983), 2016, Volume: 45, Issue:3

    Topics: Adrenal Cortex Hormones; Anus Diseases; Crohn Disease; Drug Combinations; Drug Substitution; Edema;

2016
Sulphasalazine induced three-week syndrome.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2009, Volume: 15, Issue:6

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Edema; Exanthema; Female; Hum

2009
Late onset spondyloarthropathy mimicking polymyalgia rheumatica.
    Rheumatology international, 2012, Volume: 32, Issue:5

    Topics: Age of Onset; Anti-Inflammatory Agents; Biomarkers; Blood Sedimentation; C-Reactive Protein; Diagnos

2012
Metastatic Crohn's disease of the penis: two cases.
    International urology and nephrology, 2012, Volume: 44, Issue:1

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Child; Circumcision, Male; Crohn

2012
Antagonism of protease-activated receptor 2 protects against experimental colitis.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:2

    Topics: Animals; Body Weight; Calcium Signaling; Colitis; Colon; Cytokines; Edema; HT29 Cells; Humans; Inden

2012
Significant improvement in MRI-proven bone edema is associated with protection from structural damage in very early RA patients managed using the tight control approach.
    Modern rheumatology, 2013, Volume: 23, Issue:2

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Diseases; Disease Progression; Edema;

2013
Sulphasalazine-induced aseptic meningitis with facial and nuchal edema in a patient with spondyloarthritis.
    International journal of rheumatic diseases, 2012, Volume: 15, Issue:4

    Topics: Acyclovir; Anti-Inflammatory Agents; Antirheumatic Agents; Antiviral Agents; Drug Substitution; Drug

2012
Prednisolone in giant hypertrophic gastritis (Menetrier's disease).
    The American journal of digestive diseases, 1976, Volume: 21, Issue:4

    Topics: Aged; Bronchitis; Colitis, Ulcerative; Edema; Gastritis; Humans; Hypertrophy; Male; Prednisolone; Pr

1976
Intrauterine aplastic anemia and fetal hydrops: a case report.
    Pediatric pathology, 1986, Volume: 5, Issue:2

    Topics: Abruptio Placentae; Adult; Anemia, Aplastic; Colitis, Ulcerative; Edema; Female; Fetal Death; Humans

1986
Necrotizing vasculitis and ulcerative colitis.
    British medical journal, 1974, Oct-12, Volume: 4, Issue:5936

    Topics: Adult; Ampicillin; Arthritis; Colitis, Ulcerative; Coumarins; Diarrhea; Edema; Elbow; Heparin; Human

1974