Page last updated: 2024-11-04

sulfasalazine and Cytomegalovirus

sulfasalazine has been researched along with Cytomegalovirus in 3 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Cytomegalovirus: A genus of the family HERPESVIRIDAE, subfamily BETAHERPESVIRINAE, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions. Infection with Cytomegalovirus is also seen as an opportunistic infection in AIDS.

Research Excerpts

ExcerptRelevanceReference
"We describe a patient with drug-induced hypersensitivity syndrome (DIHS) associated with human herpesvirus 6 (HHV-6) and cytomegalovirus (CMV) infection induced by sulfasalazine."3.73Drug-induced hypersensitivity syndrome associated with human herpesvirus 6 and cytomegalovirus reactivation. ( Hamaguchi, Y; Hasegawa, M; Komura, K; Nagai, M; Sato, S; Takehara, K; Yachie, A; Yukami, T, 2005)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kniazev, OV1
Lazebnik, LB1
Parfenov, AI1
Ruchkina, IN1
Shcherbakov, PL1
Konopliannikov, AG1
Mikhaĭlova, ZF1
Khomeriki, SG1
Komura, K1
Hasegawa, M1
Hamaguchi, Y1
Yukami, T1
Nagai, M1
Yachie, A1
Sato, S1
Takehara, K1
Berk, T1
Gordon, SJ1
Choi, HY1
Cooper, HS1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prevalence of Cytomegalovirus, Epstein Barr Virus and Human Herpes 6 Virus DNA in Intestinal Mucosa of Patients With Inflammatory Bowel Disease[NCT00222378]129 participants (Actual)Observational2005-04-30Completed
Relevance of Valganciclovir in Recurrent Bouts of Cryptogenic Inflammatory Bowel Diseases With an Infection by Cytomegalovirus[NCT00237653]Phase 340 participants (Anticipated)Interventional2004-02-29Terminated (stopped due to difficulty to include patients)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for sulfasalazine and Cytomegalovirus

ArticleYear
[Complete elimination of cytomegalovirus without antiviral therapy after systemic mesenchymal stromal cell transplantation in a patient with ulcerative colitis (a clinical case)].
    Terapevticheskii arkhiv, 2012, Volume: 84, Issue:12

    Topics: Adult; Anti-Inflammatory Agents; Antibodies, Viral; Biopsy; Colitis, Ulcerative; Cytomegalovirus; Cy

2012
Drug-induced hypersensitivity syndrome associated with human herpesvirus 6 and cytomegalovirus reactivation.
    The Journal of dermatology, 2005, Volume: 32, Issue:12

    Topics: Aged; Cytomegalovirus; Cytomegalovirus Infections; Drug Hypersensitivity; Exanthema Subitum; Facial

2005
Cytomegalovirus infection of the colon: a possible role in exacerbations of inflammatory bowel disease.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:5

    Topics: Adolescent; Cell Nucleus; Colitis; Cytomegalovirus; Cytomegalovirus Infections; Female; Humans; Incl

1985
Cytomegalovirus infection of the colon: a possible role in exacerbations of inflammatory bowel disease.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:5

    Topics: Adolescent; Cell Nucleus; Colitis; Cytomegalovirus; Cytomegalovirus Infections; Female; Humans; Incl

1985
Cytomegalovirus infection of the colon: a possible role in exacerbations of inflammatory bowel disease.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:5

    Topics: Adolescent; Cell Nucleus; Colitis; Cytomegalovirus; Cytomegalovirus Infections; Female; Humans; Incl

1985
Cytomegalovirus infection of the colon: a possible role in exacerbations of inflammatory bowel disease.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:5

    Topics: Adolescent; Cell Nucleus; Colitis; Cytomegalovirus; Cytomegalovirus Infections; Female; Humans; Incl

1985