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sulfasalazine and Contracture

sulfasalazine has been researched along with Contracture in 1 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Contracture: Prolonged shortening of the muscle or other soft tissue around a joint, preventing movement of the joint.

Research Excerpts

ExcerptRelevanceReference
"Fibrosis/contracture is associated with the abnormal persistence of myofibroblasts, which over-produce and contract collagen matrices."5.56Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis. ( Atluri, K; Brouillette, MJ; Fowler, TP; Fredericks, D; Khorsand, B; Martin, JA; Petersen, E; Salem, AK; Sander, E; Seol, D; Smith, S, 2020)
"Fibrosis/contracture is associated with the abnormal persistence of myofibroblasts, which over-produce and contract collagen matrices."1.56Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis. ( Atluri, K; Brouillette, MJ; Fowler, TP; Fredericks, D; Khorsand, B; Martin, JA; Petersen, E; Salem, AK; Sander, E; Seol, D; Smith, S, 2020)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Atluri, K1
Brouillette, MJ1
Seol, D1
Khorsand, B1
Sander, E1
Salem, AK1
Fredericks, D1
Petersen, E1
Smith, S1
Fowler, TP1
Martin, JA1

Other Studies

1 other study available for sulfasalazine and Contracture

ArticleYear
Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2020, Volume: 38, Issue:3

    Topics: Aminopropionitrile; Animals; Collagen; Contracture; Disease Models, Animal; Fibrosis; Hydroxyproline

2020