sulfasalazine and Coma
sulfasalazine has been researched along with Coma in 1 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The development of a toxic hepatitis and dermatitis prompted interruption of the drug." | 1.29 | Sulfasalazine-associated encephalopathy in a patient with Crohn's disease. ( Achten, E; Dewilde, D; Mast, A; Pauwels, W; Schoonjans, R; Van Den Abeele, G; Van Maele, V, 1993) |
Research
Studies (1)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Schoonjans, R | 1 |
| Mast, A | 1 |
| Van Den Abeele, G | 1 |
| Dewilde, D | 1 |
| Achten, E | 1 |
| Van Maele, V | 1 |
| Pauwels, W | 1 |
Other Studies
1 other study available for sulfasalazine and Coma
| Article | Year |
|---|---|
Sulfasalazine-associated encephalopathy in a patient with Crohn's disease.
Topics: Acute Disease; Adult; Brain; Brain Diseases; Chemical and Drug Induced Liver Injury; Coma; Crohn Dis | 1993 |