sulfasalazine has been researched along with Colonic Neoplasms in 28 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Lentinan decreased the number of tumours, inflammatory cell infiltration, atypical hyperplasia and nuclear atypia in azoxymethane/DSS-induced CAC model." | 7.91 | Therapeutic effects of lentinan on inflammatory bowel disease and colitis-associated cancer. ( Chen, S; Jing, X; Li, M; Liu, H; Liu, Y; Sun, B; Sun, T; Tian, Y; Wang, H; Yang, C; Zhang, Q; Zhao, J; Zhao, Y; Zong, S, 2019) |
| " In the current study, we investigated whether ursodeoxycholic acid (UDCA) can inhibit colitis-related mouse colon carcinogenesis and compared it with the effects of sulfasalazine." | 7.74 | Ursodeoxycholic acid versus sulfasalazine in colitis-related colon carcinogenesis in mice. ( Kohno, H; Miyamoto, S; Suzuki, R; Tanaka, T; Wakabayashi, K; Yasui, Y, 2007) |
| " Lentinan decreased the number of tumours, inflammatory cell infiltration, atypical hyperplasia and nuclear atypia in azoxymethane/DSS-induced CAC model." | 3.91 | Therapeutic effects of lentinan on inflammatory bowel disease and colitis-associated cancer. ( Chen, S; Jing, X; Li, M; Liu, H; Liu, Y; Sun, B; Sun, T; Tian, Y; Wang, H; Yang, C; Zhang, Q; Zhao, J; Zhao, Y; Zong, S, 2019) |
| " In the current study, we investigated whether ursodeoxycholic acid (UDCA) can inhibit colitis-related mouse colon carcinogenesis and compared it with the effects of sulfasalazine." | 3.74 | Ursodeoxycholic acid versus sulfasalazine in colitis-related colon carcinogenesis in mice. ( Kohno, H; Miyamoto, S; Suzuki, R; Tanaka, T; Wakabayashi, K; Yasui, Y, 2007) |
| " Therapeutic success of mesalazine may be optimized by a combination of high dose and low frequency of dosage to improve compliance." | 2.43 | Indications for 5-aminosalicylate in inflammatory bowel disease: is the body of evidence complete? ( Mulder, CJ; van Bodegraven, AA, 2006) |
| "A small group of patients with ulcerative colitis (UC) also suffer from primary sclerosing cholangitis (PSC)." | 1.30 | Differences in colonic disease activity in patients with ulcerative colitis with and without primary sclerosing cholangitis: a case control study. ( Broomé, U; Lundqvist, K, 1997) |
| "Spontaneous colitis and colon cancer in the cotton-top tamarin have been shown to resemble human ulcerative colitis and its associated cancer." | 1.29 | A prospective study of the epidemiology of colitis and colon cancer in cotton-top tamarins (Saguinus oedipus). ( Ausman, LM; Johnson, LD; King, NW; Sehgal, PK, 1996) |
| "An increased incidence of colonic cancer is associated with chronic inflammatory bowel disease." | 1.28 | The effect of therapeutic drugs used in inflammatory bowel disease on the incidence and growth of colonic cancer in the dimethylhydrazine rat model. ( Crouch, R; Davis, AE; Patterson, F, 1992) |
| "Patients with ulcerative colitis commonly have decreased folate levels, which are partially due to sulfasalazine, a competitive inhibitor of folate absorption." | 1.28 | Effect of folate supplementation on the incidence of dysplasia and cancer in chronic ulcerative colitis. A case-control study. ( Hanauer, SB; Heidenreich, PA; Kane, SV; Lashner, BA; Su, GL, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (53.57) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 5 (17.86) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Y | 1 |
| Zhao, J | 1 |
| Zhao, Y | 1 |
| Zong, S | 1 |
| Tian, Y | 1 |
| Chen, S | 1 |
| Li, M | 1 |
| Liu, H | 1 |
| Zhang, Q | 1 |
| Jing, X | 1 |
| Sun, B | 1 |
| Wang, H | 1 |
| Sun, T | 1 |
| Yang, C | 1 |
| Watanabe, Y | 1 |
| Murata, T | 1 |
| Amakawa, M | 1 |
| Miyake, Y | 1 |
| Handa, T | 1 |
| Konishi, K | 1 |
| Matsumura, Y | 1 |
| Tanaka, T | 2 |
| Takeuchi, K | 1 |
| Das, KK | 1 |
| Bajpai, M | 1 |
| Kong, Y | 1 |
| Liu, J | 1 |
| Geng, X | 1 |
| Das, KM | 1 |
| SVARTZ, N | 1 |
| Moayyeri, A | 1 |
| Daryani, NE | 1 |
| Bahrami, H | 1 |
| Haghpanah, B | 1 |
| Nayyer-Habibi, A | 1 |
| Sadatsafavi, M | 1 |
| Konson, A | 1 |
| Mahajna, JA | 1 |
| Danon, A | 1 |
| Rimon, G | 1 |
| Agbaria, R | 1 |
| van Bodegraven, AA | 1 |
| Mulder, CJ | 1 |
| Kohno, H | 1 |
| Suzuki, R | 1 |
| Yasui, Y | 1 |
| Miyamoto, S | 1 |
| Wakabayashi, K | 1 |
| Johnson, WR | 1 |
| Hughes, ES | 1 |
| McDermott, FT | 1 |
| Polglase, AL | 1 |
| Pihl, EA | 1 |
| Larizza, D | 1 |
| Boni, R | 1 |
| Johnson, LD | 1 |
| Ausman, LM | 1 |
| Sehgal, PK | 1 |
| King, NW | 1 |
| Schölmerich, J | 1 |
| Lundqvist, K | 1 |
| Broomé, U | 1 |
| Dzierzewicz, Z | 1 |
| Cwalina, B | 1 |
| Gawlik, B | 1 |
| Wilczok, T | 1 |
| Gonciarz, Z | 1 |
| Bennett, A | 1 |
| Rogers, AI | 1 |
| Davis, AE | 1 |
| Patterson, F | 1 |
| Crouch, R | 1 |
| Wolfsen, HC | 1 |
| Brubacher, LL | 1 |
| Ng, CS | 1 |
| Kayne, AL | 1 |
| Kozarek, RA | 1 |
| Lashner, BA | 1 |
| Heidenreich, PA | 1 |
| Su, GL | 1 |
| Kane, SV | 1 |
| Hanauer, SB | 1 |
| Mason, JB | 1 |
| Hall, MJ | 1 |
| Thomas, WE | 1 |
| Cooper, BT | 1 |
| Truelove, SC | 2 |
| Gheorghiu, T | 1 |
| Frotz, H | 1 |
| Fahrländer, H | 1 |
| Shalev, E | 1 |
| Köhler, R | 1 |
| Gillies, M | 1 |
| Skyring, A | 1 |
| Berndt, H | 1 |
8 reviews available for sulfasalazine and Colonic Neoplasms
| Article | Year |
|---|---|
Indications for 5-aminosalicylate in inflammatory bowel disease: is the body of evidence complete?
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Colonic Neoplasms; Humans; Inflammatory Bow | 2006 |
Inflammatory bowel disease--where are we? A review of ulcerative colitis and Crohn's disease, highlighting the problems of aetiology, epidemiology, clinical factors and management.
Topics: Adenocarcinoma; Adrenal Cortex Hormones; Colectomy; Colitis, Ulcerative; Colonic Neoplasms; Crohn Di | 1982 |
[Ulcerative rectocolitis: current clinical and therapeutic concepts].
Topics: Adrenal Cortex Hormones; Colectomy; Colitis, Ulcerative; Colonic Neoplasms; Colposcopy; Crohn Diseas | 1982 |
[Treatment and recurrence prevention ulcerative colitis].
Topics: Acute Disease; Adrenal Cortex Hormones; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroida | 1995 |
Prostaglandins as factors in diseases of the alimentary tract.
Topics: Aminosalicylic Acids; Bacterial Toxins; Carcinoma; Colonic Neoplasms; Diarrhea; Gallbladder Diseases | 1976 |
Medical management of ulcerative colitis and indications for colectomy.
Topics: Adrenal Cortex Hormones; Colectomy; Colitis, Ulcerative; Colonic Neoplasms; Humans; Recurrence; Sulf | 1988 |
Ulcerative colitis. Medical management.
Topics: Adrenocorticotropic Hormone; Allergens; Animals; Arthritis; Blood Transfusion; Colitis, Ulcerative; | 1971 |
[Diagnosis and therapy of ulcerative colitis].
Topics: Adrenal Cortex Hormones; Colitis, Ulcerative; Colonic Neoplasms; Diet Therapy; Diverticulitis; Gastr | 1969 |
20 other studies available for sulfasalazine and Colonic Neoplasms
| Article | Year |
|---|---|
Therapeutic effects of lentinan on inflammatory bowel disease and colitis-associated cancer.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Azoxymethane; Carcinoembryonic Antigen; | 2019 |
KAG-308, a newly-identified EP4-selective agonist shows efficacy for treating ulcerative colitis and can bring about lower risk of colorectal carcinogenesis by oral administration.
Topics: Administration, Oral; Animals; Azoxymethane; Benzoates; Biological Availability; Cells, Cultured; Co | 2015 |
Mesalamine suppresses the expression of TC22, a novel tropomyosin isoform associated with colonic neoplasia.
Topics: Antibodies, Monoclonal; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relationship, | 2009 |
ULCERATIVE COLITIS: CHANGES IN THE INTESTINAL WALLS AND THERAPEUTIC CONSIDERATIONS.
Topics: Adrenal Cortex Hormones; Carbon Isotopes; Colitis; Colitis, Ulcerative; Colonic Neoplasms; Mice; Neo | 1964 |
Clinical course of ulcerative colitis in patients with and without primary sclerosing cholangitis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Ster | 2005 |
The involvement of nuclear factor-kappa B in cyclooxygenase-2 overexpression in murine colon cancer cells transduced with herpes simplex virus thymidine kinase gene.
Topics: Active Transport, Cell Nucleus; Animals; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; Gene Exp | 2006 |
Ursodeoxycholic acid versus sulfasalazine in colitis-related colon carcinogenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Diseas | 2007 |
A prospective study of the epidemiology of colitis and colon cancer in cotton-top tamarins (Saguinus oedipus).
Topics: Adenocarcinoma; Animals; Body Weight; Campylobacter Infections; Colitis; Colonic Neoplasms; Disease | 1996 |
Differences in colonic disease activity in patients with ulcerative colitis with and without primary sclerosing cholangitis: a case control study.
Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Case-Control Studies; Cholangitis, Scleros | 1997 |
Isolation and evaluation of susceptibility to sulphasalazine of Desulfovibrio desulfuricans strains from the human digestive tract.
Topics: Adenoma; Adult; Anti-Bacterial Agents; Bacteriological Techniques; Biopsy; Colon; Colonic Diseases, | 1997 |
Managing ulcerative colitis.
Topics: Azathioprine; Carcinoma; Colitis, Ulcerative; Colonic Neoplasms; Humans; Prednisone; Sulfasalazine | 1976 |
The effect of therapeutic drugs used in inflammatory bowel disease on the incidence and growth of colonic cancer in the dimethylhydrazine rat model.
Topics: Adenocarcinoma; Aminosalicylic Acids; Animals; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazin | 1992 |
Refractory parastomal ulcers: a multidisciplinary approach.
Topics: Chronic Disease; Colonic Neoplasms; Enterostomy; Female; Humans; Inflammatory Bowel Diseases; Male; | 1990 |
Effect of folate supplementation on the incidence of dysplasia and cancer in chronic ulcerative colitis. A case-control study.
Topics: Adult; Colitis, Ulcerative; Colon; Colonic Neoplasms; Female; Folic Acid; Folic Acid Deficiency; Hum | 1989 |
Folate, colitis, dysplasia, and cancer.
Topics: Adenocarcinoma; Adult; Colitis, Ulcerative; Colonic Neoplasms; Female; Folic Acid Deficiency; Humans | 1989 |
Gastrocnemius myositis in a patient with inflammatory bowel disease.
Topics: Adenocarcinoma; Adult; Colectomy; Colon; Colonic Neoplasms; Crohn Disease; Female; Humans; Myositis; | 1985 |
[Ulcerative colitis].
Topics: Acute Disease; Adult; Aged; Chronic Disease; Colitis, Ulcerative; Colonic Neoplasms; Diagnosis, Diff | 1973 |
[Ulcerative colitis. Follow-up study of 160 patients observed for an average of 10 and one-half years (author's transl)].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Child; Child, Preschool; Colectomy; Colitis, Ulcer | 1974 |
[On the problem of Ulcerative colitis].
Topics: Anti-Bacterial Agents; Autoimmune Diseases; Colitis, Ulcerative; Colonic Neoplasms; Glucocorticoids; | 1966 |
Ulcerative colitis: the experience of a Sydney teaching hospital.
Topics: Acute Disease; Adolescent; Adult; Australia; Bile Duct Neoplasms; Carcinoma; Child; Child, Preschool | 1970 |