sulfasalazine has been researched along with Colitis in 226 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind therapeutic trial of azathioprine in 20 patients with acute proctocolitis was performed over a 3-month period." | 9.04 | Double-blind comparison of the effectiveness of azathioprine and sulfasalazine in idiopathic proctocolitis. Preliminary report. ( Babbini, M; Caprilli, R; Carratù, R, 1975) |
| "The current study aimed to investigate the possible role of canagliflozin (CANA), a sodium-glucose co-transporter-2 inhibitor (SGLT-2), to prevent and treat acetic acid (AA)-induced colitis in a rat model." | 8.02 | Canagliflozin, an SGLT-2 inhibitor, ameliorates acetic acid-induced colitis in rats through targeting glucose metabolism and inhibiting NOX2. ( Bayoumi, AMA; Ibrahim, YF; Khalaf, HM; Khalifa, EMMA; Morsy, MA; Rifaai, RA, 2021) |
| " Lentinan decreased the number of tumours, inflammatory cell infiltration, atypical hyperplasia and nuclear atypia in azoxymethane/DSS-induced CAC model." | 7.91 | Therapeutic effects of lentinan on inflammatory bowel disease and colitis-associated cancer. ( Chen, S; Jing, X; Li, M; Liu, H; Liu, Y; Sun, B; Sun, T; Tian, Y; Wang, H; Yang, C; Zhang, Q; Zhao, J; Zhao, Y; Zong, S, 2019) |
| "Mesalamine (5-ASA) is one of the drugs indicated as first line therapy in ulcerative colitis for induction and maintenance of remission." | 7.83 | Discovery and preclinical development of a novel prodrug conjugate of mesalamine with eicosapentaenoic acid and caprylic acid for the treatment of inflammatory bowel diseases. ( Kandula, M; Palanichamy, S; Rampal, A; Sunil Kumar, KB, 2016) |
| " In light of the antioxidant and anti-inflammatory properties of esculetin and 4-methylesculetin, the aim of this study was to investigate the effects of these compounds in an experimental model of rat colitis induced by trinitrobenzenesulphonic acid (TNBS)." | 7.76 | Intestinal anti-inflammatory activity of esculetin and 4-methylesculetin in the trinitrobenzenesulphonic acid model of rat colitis. ( Di Stasi, LC; Seito, LN; Witaicenis, A, 2010) |
| " The effect of sulfasalazine was generally of normalization of colitis-modulated genes to control levels, with very few exceptions." | 7.75 | Genomic analysis of sulfasalazine effect in experimental colitis is consistent primarily with the modulation of NF-kappaB but not PPAR-gamma signaling. ( González, R; López-Posadas, R; Martínez-Augustin, O; Sánchez de Medina, F; Suárez, MD; Zarzuelo, A, 2009) |
| " The ameliorating effect of the azo conjugate and therapeutic efficacy of the carrier system was evaluated in trinitrobenzenesulfonic acid-induced experimental colitis model." | 7.74 | Colon-specific, mutual azo prodrug of 5-aminosalicylic acid with L-tryptophan: synthesis, kinetic studies and evaluation of its mitigating effect in trinitrobenzenesulfonic acid-induced colitis in rats. ( Bhatt, L; Dhaneshwar, SS; Gairola, N; Kandpal, M; Vadnerkar, G, 2007) |
| " In the current study, we investigated whether ursodeoxycholic acid (UDCA) can inhibit colitis-related mouse colon carcinogenesis and compared it with the effects of sulfasalazine." | 7.74 | Ursodeoxycholic acid versus sulfasalazine in colitis-related colon carcinogenesis in mice. ( Kohno, H; Miyamoto, S; Suzuki, R; Tanaka, T; Wakabayashi, K; Yasui, Y, 2007) |
| " The present study examined intestinal anti-inflammatory activity of coumarin and its derivative, the 4-hydroxycoumarin on experimental ulcerative colitis in rats." | 7.74 | Intestinal anti-inflammatory activity of coumarin and 4-hydroxycoumarin in the trinitrobenzenesulphonic acid model of rat colitis. ( Cestari, SH; Di Stasi, LC; Luchini, AC; Pellizzon, CH; Rodrigues-Orsi, P; Seito, LN; Witaicenis, A, 2008) |
| "Alendronate treatment (25 or 75 mg kg(-1) day(-1)) resulted in a decrease in the colonic damage score and loss of body weight (at 25 mg kg(-1) day(-1) only)." | 7.74 | The bisphosphonate alendronate improves the damage associated with trinitrobenzenesulfonic acid-induced colitis in rats. ( Ballester, I; Daddaoua, A; López-Posadas, R; Martínez-Augustin, O; Nieto, A; Sánchez de Medina, F; Suárez, MD; Zarzuelo, A, 2007) |
| "The anti-inflammatory effect of three flavonoids from the root of Scutellaria baicalensis (baicalein, baicalin and wogonin) was evaluated in a murine model of acute experimental colitis induced by dextran sulfate sodium (DSS)." | 7.71 | Evaluation of the anti-inflammatory effect of baicalein on dextran sulfate sodium-induced colitis in mice. ( Cho, S; Cyong, JC; Hong, T; Jin, GB, 2002) |
| " This study was conducted to compare the effect of D-002 and sulfasalazine on acetic acid-induced colitis in rats administered at 1, 5." | 7.70 | Comparative study of D-002 versus sulfasalazine on acetic acid-induced colitis in rats. ( Carbajal, D; Más, R; Molina, V; Noa, M; Valdés, S, 2000) |
| "DSS was used to induce intestinal inflammation in conventional Balb/c mice and athymic nu/nu CD-1(BR) mice, and the well-documented 5-aminosalicylic acid (5-ASA) based anticolitis drugs sulphasalazine (SASP) and olsalazine (OLZ) were used to study therapeutic effects." | 7.70 | Experimental colitis induced by dextran sulphate sodium in mice: beneficial effects of sulphasalazine and olsalazine. ( Axelsson, LG; Bylund-Fellenius, AC; Landström, E, 1998) |
| "The efficacy of zileuton, a new 5-lipoxygenase inhibitor, was investigated in comparison with sulphasalazine in an experimental model of rat colitis." | 7.68 | Effects of zileuton, a new 5-lipoxygenase inhibitor, in experimentally induced colitis in rats. ( Camerini, R; Caputi, AP; Graziani, P; Squadrito, F; Zingarelli, B, 1993) |
| "A patient is described with chronic colitis, watery diarrhea, and colonic mucosal subepithelial collagen deposition that resolved while being treated with sulfasalazine." | 7.67 | Sulfasalazine in treatment of collagenous colitis. Case report and review of the literature. ( Pattee, B; Smith, J; Weidner, N, 1984) |
| "A patient with rheumatoid arthritis and collagenous colitis apparently responding to sulfasalazine and prednisolone enemas is reported." | 7.67 | Collagenous colitis: possible response to sulfasalazine and local steroid therapy. ( Farah, DA; Lee, FD; McLay, A; Mills, PR; Russell, RI, 1985) |
| "Collagenous colitis has been associated with rheumatoid arthritis in only a few cases." | 6.37 | Collagenous colitis and rheumatoid arthritis with response to sulfasalazine. A case report and review of the literature. ( Okon, E; Pollak, A; Stalnikowicz, R; Wengrower, D, 1987) |
| "Ulcerative colitis is a chronic inflammatory disease with high mortality and morbidity worldwide." | 5.91 | Comparative treatment of Sulfasalazine+Ezetimibe combination and Sulfasalazine in a rat model with induced colitis. ( Abu-Raghif, A; Jaafar, FR, 2023) |
| "Sulfasalazine (SASP) was used as the positive control." | 5.62 | The Regulatory Effects of Licochalcone A on the Intestinal Epithelium and Gut Microbiota in Murine Colitis. ( Cao, L; Li, N; Qing, DG; Si, JY; Sun, Y; Wang, JC; Xu, XQ; Zhang, J, 2021) |
| "Ectoine is a compatible solute produced by aerobic chemoheterotrophic and halophilic/halotolerant bacteria, where it acts as osmoprotectant and effective biomembrane stabilizer, protecting the producing cells from extreme environmental stress." | 5.39 | Novel effects of ectoine, a bacteria-derived natural tetrahydropyrimidine, in experimental colitis. ( Abdallah, DM; Abdel-Aziz, H; Khayyal, MT; Lentzen, G; Wadie, W, 2013) |
| "Compared with the untreated colitis group, the curcumin-treated group showed significant decreases in the disease activity index, colonic mucosa damage index, histological score, myeloperoxidase activity, and expressions of NF-κB mRNA, IL-27 mRNA, TLR4 protein, NF-κB p65 protein, and IL-27 p28 protein (p < 0." | 5.39 | Curcumin improves TNBS-induced colitis in rats by inhibiting IL-27 expression via the TLR4/NF-κB signaling pathway. ( Chen, L; Liao, H; Lv, X; Zeng, Z; Zhan, L, 2013) |
| "Colitis was induced in rat by instillation of trinitrobenzenesulphonic acid (TNBS)." | 5.38 | Suppression of TNBS-induced colitis in rats by 4-methylesculetin, a natural coumarin: comparison with prednisolone and sulphasalazine. ( Di Stasi, LC; Felisbino, SL; Gálvez, J; Garrido-Mesa, N; Hiruma-Lima, CA; Luchini, AC; Utrilla, P; Witaicenis, A, 2012) |
| "Repeated colitis was induced by administration of 4 cycles of 4% dextran sulfate sodium (DSS); The severity of colitis was assessed on the basis of clinical signs, colon length, and histology scores." | 5.36 | Amelioration of dextran sulfate sodium-induced chronic colitis by sulfasalazine salicylazosulfapyridine via reducing NF-kappaB transcription factor p65 recruitment to ICAM-1 gene promoters. ( Hongzhu, D; Song, L; Zhao, W, 2010) |
| "Sulphasalazine, THC and CBD proved beneficial in this model of colitis with the dose-response relationship for the phytocannabinoids showing a bell-shaped pattern on the majority of parameters (optimal THC and CBD dose, 10 mg." | 5.36 | The effects of Delta-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis. ( Jamontt, JM; Molleman, A; Parsons, ME; Pertwee, RG, 2010) |
| " Because sulfasalazine presents serious side effects through long-term use at high doses, the aim of the present study was to evaluate the preventative effect of polydextrose on trinitrobenzenesulfonic acid-induced intestinal inflammation and its effects on the intestinal anti-inflammatory activity of sulfasalazine." | 5.36 | Dietary polydextrose prevents inflammatory bowel disease in trinitrobenzenesulfonic acid model of rat colitis. ( Di Stasi, LC; Fruet, AC; Salem, L; Witaicenis, A, 2010) |
| "Lansoprazole is a proton pump inhibitor widely prescribed for gastroesophageal reflux and benign peptic ulcer disease." | 5.32 | Diarrhea associated with lansoprazole. ( Mukherjee, S, 2003) |
| "A pharmacokinetic model of colon-specific drug delivery developed in a previous study has been validated by use of 5-aminosalicylic acid (5-ASA) as a model anti-inflammatory drug." | 5.30 | Validation of a pharmacokinetic model of colon-specific drug delivery and the therapeutic effects of chitosan capsules containing 5-aminosalicylic acid on 2,4,6-trinitrobenzenesulphonic acid-induced colitis in rats. ( Fujita, T; Muranishi, S; Odoriba, T; Okabe, S; Terabe, A; Tozaki, H; Yamamoto, A, 1999) |
| "4-Aminosalicylic acid seems to be a suitable drug for improving the clinical symptoms of ulcerative proctitis." | 5.28 | Experience with topical administration of 4-aminosalicylic acid in ulcerative colitis. ( Karacsony, G; Nagy, F; Varro, V, 1989) |
| "A diagnosis of idiopathic ulcerative colitis was made in a previously healthy 9-year-old boy." | 5.27 | Sulfasalazine-induced colitis complicating idiopathic ulcerative colitis. ( Hershfield, NB; Machin, GA; Ring, FA; Scott, RB, 1984) |
| "A double-blind therapeutic trial of azathioprine in 20 patients with acute proctocolitis was performed over a 3-month period." | 5.04 | Double-blind comparison of the effectiveness of azathioprine and sulfasalazine in idiopathic proctocolitis. Preliminary report. ( Babbini, M; Caprilli, R; Carratù, R, 1975) |
| " We investigated the effect of melittin peptide alone and in combination with sulfasalazine on improving the clinical symptoms among DSS-induced colitis models." | 4.12 | Evaluation of the therapeutic effect of melittin peptide on the ulcerative colitis mouse model. ( Amel Jamehdar, S; Ghazvini, K; Reza Akbari Eidgahi, M; Yaghoubi, A, 2022) |
| "The current study aimed to investigate the possible role of canagliflozin (CANA), a sodium-glucose co-transporter-2 inhibitor (SGLT-2), to prevent and treat acetic acid (AA)-induced colitis in a rat model." | 4.02 | Canagliflozin, an SGLT-2 inhibitor, ameliorates acetic acid-induced colitis in rats through targeting glucose metabolism and inhibiting NOX2. ( Bayoumi, AMA; Ibrahim, YF; Khalaf, HM; Khalifa, EMMA; Morsy, MA; Rifaai, RA, 2021) |
| " Lentinan decreased the number of tumours, inflammatory cell infiltration, atypical hyperplasia and nuclear atypia in azoxymethane/DSS-induced CAC model." | 3.91 | Therapeutic effects of lentinan on inflammatory bowel disease and colitis-associated cancer. ( Chen, S; Jing, X; Li, M; Liu, H; Liu, Y; Sun, B; Sun, T; Tian, Y; Wang, H; Yang, C; Zhang, Q; Zhao, J; Zhao, Y; Zong, S, 2019) |
| "To test whether sulpiride (SP), an anti-psychotic and prokinetic drug, shows beneficial effects on experimental murine colitis, a colon-targeted prodrug of SP, 5-(aminoethanoylsulfamoyl)-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide (glycylsulpiride (GSP)), was synthesized and its colonic delivery and therapeutic activity against 2,4-dinitrobenzenesulfonic acid (DNBS)-induced rat colitis were assessed." | 3.91 | Therapeutic switching of sulpiride, an anti-psychotic and prokinetic drug, to an anti-colitic drug using colon-specific drug delivery. ( Jeong, S; Jung, Y; Kim, D; Kim, W; Yoo, JW, 2019) |
| " The aim of this study was to evaluate the effect of AMFJ in a rat TNBSinduced colitis model and to compare the effect of the juice with that of sulfasalazine." | 3.88 | Aronia melanocarpa fruit juice ameliorates the symptoms of inflammatory bowel disease in TNBS-induced colitis in rats. ( Kuzmanov, A; Kuzmanova, V; Tzaneva, M; Valcheva-Kuzmanova, S, 2018) |
| "Because the AM or TH extracts were far superior in preventing DSS-induced colitis than sulfasalazine, AM or TH extracts can be considered natural agents that can prevent IBD relapse." | 3.85 | Heme Oxygenase-1 Induction and Anti-inflammatory Actions of ( Go, EJ; Hahm, KB; Han, JG; Han, KH; Han, YM; Jeong, M; Kim, H; Kwon, O; Park, J; Park, JM, 2017) |
| " The fruit extract (50, 100 and 200mg/kg) treated enterocolitis rats significantly retain their body weight, organ weight, stool consistency, macroscopic score, histology, haematological parameters, antioxidative enzyme levels and also reduce the serum marker levels and myeloperoxidase (MPO) activity compared to prednisolone (2mg/kg) and sulfasalazine (50mg/kg) drugs." | 3.85 | Study of intestinal anti-inflammatory activity of Phoenix loureiroi Kunth (Arecaceae) fruit. ( Murugan, R; Parimelazhagan, T; Saravanan, S, 2017) |
| " The strong inhibitory activity of compound 55 against an in vivo colitis model was confirmed by its dose-dependent inhibitory activity in a rat model of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis, demonstrating compound 55 as a new potential candidate for the development of therapeutics against IBD." | 3.85 | Discovery and structure-activity relationship studies of 2-benzylidene-2,3-dihydro-1H-inden-1-one and benzofuran-3(2H)-one derivatives as a novel class of potential therapeutics for inflammatory bowel disease. ( Banskota, S; Bist, G; Gurung, P; Kadayat, TM; Kim, JA; Lee, ES; Shrestha, A; Thapa Magar, TB, 2017) |
| "Mesalamine (5-ASA) is one of the drugs indicated as first line therapy in ulcerative colitis for induction and maintenance of remission." | 3.83 | Discovery and preclinical development of a novel prodrug conjugate of mesalamine with eicosapentaenoic acid and caprylic acid for the treatment of inflammatory bowel diseases. ( Kandula, M; Palanichamy, S; Rampal, A; Sunil Kumar, KB, 2016) |
| "This study aimed to evaluate potential protecting effect of ML and its major constituent, eucalyptol, against acetic acid-induced colitis in rats, a model of human inflammatory bowel disease (IBD)." | 3.83 | Mentha longifolia protects against acetic-acid induced colitis in rats. ( Abdallah, HM; Ali, SS; Murad, HA, 2016) |
| "Earlier studies showed that the compatible solute ectoine (1) given prophylactically before induction of colitis by 2,4,6-trinitrobenzenesulfonic acid (TNBS) in rats prevented histological changes induced in the colon and the associated rise in inflammatory mediators." | 3.81 | Bacteria-Derived Compatible Solutes Ectoine and 5α-Hydroxyectoine Act as Intestinal Barrier Stabilizers to Ameliorate Experimental Inflammatory Bowel Disease. ( Abdel-Aziz, H; Efferth, T; Khayyal, MT; Scherner, O; Wadie, W, 2015) |
| "), which reduced mortality and pathology (including colon obstruction, ulceration, wall thickness, and myeloperoxidase release) more effectively than the clinically used drug sulfasalazine (100 mg/kg/day p." | 3.78 | Antagonism of protease-activated receptor 2 protects against experimental colitis. ( Cotterell, AJ; Do, AT; Fairlie, DP; Liu, L; Lohman, RJ; Suen, J; Vesey, DA, 2012) |
| " In light of the antioxidant and anti-inflammatory properties of esculetin and 4-methylesculetin, the aim of this study was to investigate the effects of these compounds in an experimental model of rat colitis induced by trinitrobenzenesulphonic acid (TNBS)." | 3.76 | Intestinal anti-inflammatory activity of esculetin and 4-methylesculetin in the trinitrobenzenesulphonic acid model of rat colitis. ( Di Stasi, LC; Seito, LN; Witaicenis, A, 2010) |
| " In vivo healing potential of KET-GLY was evaluated in acetic acid-induced experimental colitis model." | 3.75 | Optimized prodrug approach: a means for achieving enhanced anti-inflammatory potential in experimentally induced colitis. ( Dabas, S; Pathak, K; Philip, AK, 2009) |
| " The prodrugs exhibited comparable ameliorating effect as that of sulfasalazine on trinitrobenzenesulfonic acid-induced experimental colitis in rats with a better safety profile." | 3.75 | Synthesis, kinetic studies and pharmacological evaluation of mutual azo prodrugs of 5-aminosalicylic acid for colon-specific drug delivery in inflammatory bowel disease. ( Bhatt, L; Dhaneshwar, SS; Gairola, N; Kadam, SS; Kandpal, M; Rathi, B; Vadnerkar, G, 2009) |
| " The ameliorating effect of the azo conjugate and therapeutic efficacy of the carrier system was evaluated in trinitrobenzenesulfonic acid-induced experimental colitis model." | 3.74 | Colon-specific, mutual azo prodrug of 5-aminosalicylic acid with L-tryptophan: synthesis, kinetic studies and evaluation of its mitigating effect in trinitrobenzenesulfonic acid-induced colitis in rats. ( Bhatt, L; Dhaneshwar, SS; Gairola, N; Kandpal, M; Vadnerkar, G, 2007) |
| " In the current study, we investigated whether ursodeoxycholic acid (UDCA) can inhibit colitis-related mouse colon carcinogenesis and compared it with the effects of sulfasalazine." | 3.74 | Ursodeoxycholic acid versus sulfasalazine in colitis-related colon carcinogenesis in mice. ( Kohno, H; Miyamoto, S; Suzuki, R; Tanaka, T; Wakabayashi, K; Yasui, Y, 2007) |
| " The present study examined intestinal anti-inflammatory activity of coumarin and its derivative, the 4-hydroxycoumarin on experimental ulcerative colitis in rats." | 3.74 | Intestinal anti-inflammatory activity of coumarin and 4-hydroxycoumarin in the trinitrobenzenesulphonic acid model of rat colitis. ( Cestari, SH; Di Stasi, LC; Luchini, AC; Pellizzon, CH; Rodrigues-Orsi, P; Seito, LN; Witaicenis, A, 2008) |
| "Alendronate treatment (25 or 75 mg kg(-1) day(-1)) resulted in a decrease in the colonic damage score and loss of body weight (at 25 mg kg(-1) day(-1) only)." | 3.74 | The bisphosphonate alendronate improves the damage associated with trinitrobenzenesulfonic acid-induced colitis in rats. ( Ballester, I; Daddaoua, A; López-Posadas, R; Martínez-Augustin, O; Nieto, A; Sánchez de Medina, F; Suárez, MD; Zarzuelo, A, 2007) |
| " In acetic acid-induced colitis in the rat, levels of malondialdehyde were found to be more markedly reduced with MED15 than with 5-aminosalicylic acid." | 3.72 | Impact on the bowel of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug. ( Belogi, L; Bettelli, E; Mezzadri, CM; Tubaro, E, 2003) |
| "The anti-inflammatory effect of three flavonoids from the root of Scutellaria baicalensis (baicalein, baicalin and wogonin) was evaluated in a murine model of acute experimental colitis induced by dextran sulfate sodium (DSS)." | 3.71 | Evaluation of the anti-inflammatory effect of baicalein on dextran sulfate sodium-induced colitis in mice. ( Cho, S; Cyong, JC; Hong, T; Jin, GB, 2002) |
| "DSS was used to induce intestinal inflammation in conventional Balb/c mice and athymic nu/nu CD-1(BR) mice, and the well-documented 5-aminosalicylic acid (5-ASA) based anticolitis drugs sulphasalazine (SASP) and olsalazine (OLZ) were used to study therapeutic effects." | 3.70 | Experimental colitis induced by dextran sulphate sodium in mice: beneficial effects of sulphasalazine and olsalazine. ( Axelsson, LG; Bylund-Fellenius, AC; Landström, E, 1998) |
| " This study was conducted to compare the effect of D-002 and sulfasalazine on acetic acid-induced colitis in rats administered at 1, 5." | 3.70 | Comparative study of D-002 versus sulfasalazine on acetic acid-induced colitis in rats. ( Carbajal, D; Más, R; Molina, V; Noa, M; Valdés, S, 2000) |
| "1 yr) had been treated with antidiarrheals (6), sulfasalazine (3), discontinuation of NSAIDS (3), reversal of jejunoilial bypass (1), or nothing (4)." | 3.69 | Collagenous colitis: histopathology and clinical course. ( Appelman, HD; Barnett, JL; Goff, JS; Pelke, T, 1997) |
| "The efficacy of zileuton, a new 5-lipoxygenase inhibitor, was investigated in comparison with sulphasalazine in an experimental model of rat colitis." | 3.68 | Effects of zileuton, a new 5-lipoxygenase inhibitor, in experimentally induced colitis in rats. ( Camerini, R; Caputi, AP; Graziani, P; Squadrito, F; Zingarelli, B, 1993) |
| "A patient is described with chronic colitis, watery diarrhea, and colonic mucosal subepithelial collagen deposition that resolved while being treated with sulfasalazine." | 3.67 | Sulfasalazine in treatment of collagenous colitis. Case report and review of the literature. ( Pattee, B; Smith, J; Weidner, N, 1984) |
| "A patient with rheumatoid arthritis and collagenous colitis apparently responding to sulfasalazine and prednisolone enemas is reported." | 3.67 | Collagenous colitis: possible response to sulfasalazine and local steroid therapy. ( Farah, DA; Lee, FD; McLay, A; Mills, PR; Russell, RI, 1985) |
| "A man with Crohn's colitis developed eosinophilic pneumonia after treatment with sulfasalazine." | 3.67 | Olsalazine as an alternative therapy in a patient with sulfasalazine-induced eosinophilic pneumonia. ( Nadorp, JH; Scherpenisse, J; van den Bosch, JM; van der Valk, PD; van Hees, PA, 1988) |
| "Hematologic studies, including serum and RBC folate assays, were done on 45 outpatients with chronic colitis who either took sulfasalazine (n = 27) or did not use it (n = 18)." | 3.66 | Folate status in patients receiving maintenance doses of sulfasalazine. ( Green, R; Longstreth, GF, 1983) |
| "Microscopic colitis is a recently recognized cause of diarrhoea, predominantly affecting older women, but its response to treatment is poorly documented." | 2.67 | Response to treatment of microscopic colitis. ( Fasoli, R; Jewell, DP, 1994) |
| "Lymphocytic colitis is a rare clinicopathologic syndrome, characterized by chronic watery diarrhea, diffuse inflammatory changes in the colonic mucous in spite of normal findings on colonoscopy and marked intraepithelial lymphocytic infiltration on biopsy." | 2.41 | [Lymphocytic colitis: hypopotassemia as a complication and an association with toxic multinodular goiter]. ( Arenas Gracia, M; Calduch Broseta, JV; Martínez López, V; Mata Medina, B; Segarra Soria, MM; Serrano Corredor, MS, 2000) |
| "Collagenous colitis has been associated with rheumatoid arthritis in only a few cases." | 2.37 | Collagenous colitis and rheumatoid arthritis with response to sulfasalazine. A case report and review of the literature. ( Okon, E; Pollak, A; Stalnikowicz, R; Wengrower, D, 1987) |
| "Ulcerative colitis is a chronic inflammatory disease with high mortality and morbidity worldwide." | 1.91 | Comparative treatment of Sulfasalazine+Ezetimibe combination and Sulfasalazine in a rat model with induced colitis. ( Abu-Raghif, A; Jaafar, FR, 2023) |
| "against ulcerative colitis and its underlying mechanisms remain unclear." | 1.91 | Phytochemical analysis of Origanum majorana L. extract and investigation of its antioxidant, anti-inflammatory and immunomodulatory effects against experimentally induced colitis downregulating Th17 cells. ( Abdelbagi, O; Babateen, O; Badawy, AM; Baokbah, TAS; Elazab, ST; Ibrahim, MM; Mahmoud, ME; Qusty, NF; Saati, AA; Taha, M, 2023) |
| "Acute colitis was induced in rats by oral administration of DSS 3." | 1.72 | The synbiotic mixture of Bacillus licheniformis and Saccharomyces cerevisiae extract aggravates dextran sulfate sodium induced colitis in rats. ( Abdallah, HM; Ali, RI; Ghonimi, WAM; Mohamed, AA; Rhouma, NR; Salem, GA, 2022) |
| "To apply the metabolite for the treatment of colitis, 3-IPA was coupled with acidic amino acids to yield colon-targeted 3-IPA, 3-IPA-aspartic acid (IPA-AA) and 3-IPA-glutamic acid (IPA-GA)." | 1.62 | Preparation and Evaluation of Colon-Targeted Prodrugs of the Microbial Metabolite 3-Indolepropionic Acid as an Anticolitic Agent. ( Ju, S; Jung, Y; Kim, S; Lee, H; Min, DS; Park, S; Yoo, JW; Yoon, IS, 2021) |
| "Sulfasalazine (SASP) was used as the positive control." | 1.62 | The Regulatory Effects of Licochalcone A on the Intestinal Epithelium and Gut Microbiota in Murine Colitis. ( Cao, L; Li, N; Qing, DG; Si, JY; Sun, Y; Wang, JC; Xu, XQ; Zhang, J, 2021) |
| "The potential of probiotics for treating ulcerative colitis (UC) has attracted increasing attention." | 1.56 | Combination of probiotics with different functions alleviate DSS-induced colitis by regulating intestinal microbiota, IL-10, and barrier function. ( Cui, J; Ma, W; Ning, K; Wang, Y; Xiang, H; Xiang, JY; Xie, Q; Zhang, Y, 2020) |
| "For the efficient treatment of colitis, SFC was coupled with acidic amino acids to yield SFC-aspartic acid (SFC-AA) and SFC-glutamic acid, and their colon targetability and therapeutic effects were assessed as an anticolitic agent in a 2,4-dinitrobenezenesulfonic acid-induced rat colitis model." | 1.51 | Colon-Targeted Delivery Facilitates the Therapeutic Switching of Sofalcone, a Gastroprotective Agent, to an Anticolitic Drug via Nrf2 Activation. ( Jeong, S; Ju, S; Jung, Y; Kim, S; Kim, W; Lee, H; Yoo, JW; Yoon, IS, 2019) |
| "Compared with the untreated colitis group, the curcumin-treated group showed significant decreases in the disease activity index, colonic mucosa damage index, histological score, myeloperoxidase activity, and expressions of NF-κB mRNA, IL-27 mRNA, TLR4 protein, NF-κB p65 protein, and IL-27 p28 protein (p < 0." | 1.39 | Curcumin improves TNBS-induced colitis in rats by inhibiting IL-27 expression via the TLR4/NF-κB signaling pathway. ( Chen, L; Liao, H; Lv, X; Zeng, Z; Zhan, L, 2013) |
| "Ectoine is a compatible solute produced by aerobic chemoheterotrophic and halophilic/halotolerant bacteria, where it acts as osmoprotectant and effective biomembrane stabilizer, protecting the producing cells from extreme environmental stress." | 1.39 | Novel effects of ectoine, a bacteria-derived natural tetrahydropyrimidine, in experimental colitis. ( Abdallah, DM; Abdel-Aziz, H; Khayyal, MT; Lentzen, G; Wadie, W, 2013) |
| "Colitis was induced by administration of 3% DSS in drinking water to mice for 7days followed by 5days of normal drinking water." | 1.39 | Establishment and validation of a new semi-chronic dextran sulfate sodium-induced model of colitis in mice. ( Igaki, K; Sha, T; Tsuchimori, N; Watanabe, T; Yamasaki, M, 2013) |
| "Colitis was induced in rat by instillation of trinitrobenzenesulphonic acid (TNBS)." | 1.38 | Suppression of TNBS-induced colitis in rats by 4-methylesculetin, a natural coumarin: comparison with prednisolone and sulphasalazine. ( Di Stasi, LC; Felisbino, SL; Gálvez, J; Garrido-Mesa, N; Hiruma-Lima, CA; Luchini, AC; Utrilla, P; Witaicenis, A, 2012) |
| "Colitis was induced in vivo by intrarectal administration of TNBS in male ICR mice." | 1.37 | Kalopanaxsaponin A ameliorates experimental colitis in mice by inhibiting IRAK-1 activation in the NF-κB and MAPK pathways. ( Joh, EH; Kim, DH, 2011) |
| " Because sulfasalazine presents serious side effects through long-term use at high doses, the aim of the present study was to evaluate the preventative effect of polydextrose on trinitrobenzenesulfonic acid-induced intestinal inflammation and its effects on the intestinal anti-inflammatory activity of sulfasalazine." | 1.36 | Dietary polydextrose prevents inflammatory bowel disease in trinitrobenzenesulfonic acid model of rat colitis. ( Di Stasi, LC; Fruet, AC; Salem, L; Witaicenis, A, 2010) |
| "Repeated colitis was induced by administration of 4 cycles of 4% dextran sulfate sodium (DSS); The severity of colitis was assessed on the basis of clinical signs, colon length, and histology scores." | 1.36 | Amelioration of dextran sulfate sodium-induced chronic colitis by sulfasalazine salicylazosulfapyridine via reducing NF-kappaB transcription factor p65 recruitment to ICAM-1 gene promoters. ( Hongzhu, D; Song, L; Zhao, W, 2010) |
| "Sulphasalazine, THC and CBD proved beneficial in this model of colitis with the dose-response relationship for the phytocannabinoids showing a bell-shaped pattern on the majority of parameters (optimal THC and CBD dose, 10 mg." | 1.36 | The effects of Delta-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis. ( Jamontt, JM; Molleman, A; Parsons, ME; Pertwee, RG, 2010) |
| " This methodology provides unique and objective in vivo measures of inflammation that can guide dosing strategies, enhancing colitis research effectiveness and the assessment of potential IBD therapeutics." | 1.35 | Progression and variability of TNBS colitis-associated inflammation in rats assessed by contrast-enhanced and T2-weighted MRI. ( Hobson, AR; James, MF; Kruidenier, L; Lewis, HD; McCleary, S; Pohlmann, A; Robinson, A; Tilling, LC; Warnock, LC; Woolmer, O, 2009) |
| "Colitis was induced by a single intracolonic administration of TNBS dissolved in 35% ethanol." | 1.35 | Effect of different doses of Manuka honey in experimentally induced inflammatory bowel disease in rats. ( Avti, PK; Khanduja, KL; Medhi, B; Pandhi, P; Prakash, A; Saikia, UN, 2008) |
| "Treatment with sulfasalazine, doxantrazole, quercetin, or nedocromil did not increase the histamine concentration or the mast cell number in the colon on day 26, thereby showing absence of degranulation of these cells." | 1.35 | Relationship between mast cells and the colitis with relapse induced by trinitrobenzesulphonic acid in Wistar rats. ( de Oliveira, DM; Di Stasi, LC; Gomes, JC; Luchini, AC; Pellizzon, CH, 2009) |
| "Lansoprazole is a proton pump inhibitor widely prescribed for gastroesophageal reflux and benign peptic ulcer disease." | 1.32 | Diarrhea associated with lansoprazole. ( Mukherjee, S, 2003) |
| "Colitis was induced by feeding a diet containing 0." | 1.31 | Dietary fiber fraction of germinated barley foodstuff attenuated mucosal damage and diarrhea, and accelerated the repair of the colonic mucosa in an experimental colitis. ( Andoh, A; Araki, Y; Bamba, T; Hibi, T; Iwanaga, T; Kanauchi, O; Mitsuyama, K; Nakamura, T; Suzuki, A, 2001) |
| "Colitis was induced in 29 rats by intracolonic administration of trinitrobenzensulfonic acid." | 1.30 | 5-ASA-glutamate protects rats from inflammatory bowel disease induced by intracolonic administration of trinitrobenzensulfonic acid. ( Aburbeh, AG; Balò, S; Bartoli, G; Clementi, M; Clerici, C; Gentili, G; Giansanti, M; Gresele, P; Mezzasoma, AM; Modesto, R; Morelli, A; Morelli, O; Pellicciari, R, 1998) |
| "Diarrhea is a non-specific symptom which may be associated with Addison's disease and several causes had been demonstrated in the aetiology." | 1.30 | Collagenous colitis in a patient with Addison's disease: a case report. ( Bayram, F; Keleştimur, F; Kirgin, A; Ozbakir, O; Patiroglu, T; Unlühizarci, K; Yücesoy, M, 1998) |
| "A pharmacokinetic model of colon-specific drug delivery developed in a previous study has been validated by use of 5-aminosalicylic acid (5-ASA) as a model anti-inflammatory drug." | 1.30 | Validation of a pharmacokinetic model of colon-specific drug delivery and the therapeutic effects of chitosan capsules containing 5-aminosalicylic acid on 2,4,6-trinitrobenzenesulphonic acid-induced colitis in rats. ( Fujita, T; Muranishi, S; Odoriba, T; Okabe, S; Terabe, A; Tozaki, H; Yamamoto, A, 1999) |
| "In Crohn's disease as well as in ulcerative colitis steroids are of major importance in the treatment of active disease." | 1.29 | [Current therapeutic possibilities in chronic inflammatory intestinal diseases]. ( Schölmerich, J, 1995) |
| "Spontaneous colitis and colon cancer in the cotton-top tamarin have been shown to resemble human ulcerative colitis and its associated cancer." | 1.29 | A prospective study of the epidemiology of colitis and colon cancer in cotton-top tamarins (Saguinus oedipus). ( Ausman, LM; Johnson, LD; King, NW; Sehgal, PK, 1996) |
| "Prednisolone was most effective with a response rate of 82%, but the required dose was often high and the effect was not sustained after withdrawal." | 1.29 | Collagenous colitis: a retrospective study of clinical presentation and treatment in 163 patients. ( Abrahamsson, H; Bohr, J; Eriksson, S; Järnerot, G; Tysk, C, 1996) |
| "Microscopic colitis has been observed to precede collagenous colitis in some patients." | 1.28 | Collagenous colitis as a cause of chronic diarrhea. ( Bott, SJ, 1990) |
| "4-Aminosalicylic acid seems to be a suitable drug for improving the clinical symptoms of ulcerative proctitis." | 1.28 | Experience with topical administration of 4-aminosalicylic acid in ulcerative colitis. ( Karacsony, G; Nagy, F; Varro, V, 1989) |
| "These four patients (two with Crohn's disease and two with nonspecific colitis) were entered into the second phase of the study." | 1.28 | Does proctosigmoiditis in inflammatory bowel disease presage the imminent onset of symptoms? ( Aiges, H; Daum, F; Kahn, E; Markowitz, J; Rosa, J; Simpser, E, 1989) |
| "A diagnosis of idiopathic ulcerative colitis was made in a previously healthy 9-year-old boy." | 1.27 | Sulfasalazine-induced colitis complicating idiopathic ulcerative colitis. ( Hershfield, NB; Machin, GA; Ring, FA; Scott, RB, 1984) |
| "The clinical effect was evaluated by Crohn's Disease Activity Index (CDAI) and serum(s)-orosomucoid value." | 1.26 | Clinical effect of metronidazole and sulfasalazine on Crohn's disease in relation to changes in the fecal flora. ( Danielsson, D; Järnerot, G; Krook, A, 1981) |
| "In eleven pregnant patients with ulcerative colitis or Crohn's disease who were treated with sulphasalazine (SASP) the serum concentrations of SASP and sulphapyridine (SP) were measured at delivery." | 1.26 | Placental transfer of sulphasalazine and sulphapyridine and some of its metabolites. ( Esbjörner, E; Into-Malmberg, MB; Järnerot, G, 1981) |
| "Microscopic colitis is responsible for a proportion of cases of intractable diarrhoea of obscure origin and rectal and colonic biopsies sould be undertaken in such cases." | 1.26 | Microscopic colitis-a cause of chronic watery diarrhoea. ( Ball, JA; Dawson, AM; Kingham, JG; Levison, DA, 1982) |
| "Ileocolitis was the most (52%) and colitis the least (9%) common form of disease with diffuse small bowel or ileal disease each comprising nearly 20% of the study group." | 1.26 | Prognosis in children with Crohn's disease. ( Gryboski, JD; Spiro, HM, 1978) |
| "Patients with proctocolitis and Crohn's disease who were not receiving sulphasalazine had a similar flora which did not differ in any way from the normal." | 1.25 | Effects of sulphasalazine (Salazopyrin) on faecal flora in patients with inflammatory bowel disease. ( Hill, MJ; Lendrum, R; Walker, G; West, B, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 103 (45.58) | 18.7374 |
| 1990's | 41 (18.14) | 18.2507 |
| 2000's | 28 (12.39) | 29.6817 |
| 2010's | 35 (15.49) | 24.3611 |
| 2020's | 19 (8.41) | 2.80 |
| Authors | Studies |
|---|---|
| Hibi, S | 1 |
| Okamoto, Y | 1 |
| Tagami, K | 1 |
| Numata, H | 1 |
| Kobayashi, N | 1 |
| Shinoda, M | 1 |
| Kawahara, T | 1 |
| Murakami, M | 1 |
| Oketani, K | 1 |
| Inoue, T | 1 |
| Dhaneshwar, SS | 4 |
| Kandpal, M | 3 |
| Vadnerkar, G | 4 |
| Rathi, B | 2 |
| Kadam, SS | 2 |
| Gairola, N | 2 |
| Bhatt, L | 2 |
| Chail, M | 1 |
| Patil, M | 1 |
| Naqvi, S | 1 |
| Abdel-Aziz, H | 2 |
| Wadie, W | 2 |
| Scherner, O | 1 |
| Efferth, T | 1 |
| Khayyal, MT | 2 |
| Mu, HX | 1 |
| Liu, J | 2 |
| Fatima, S | 1 |
| Lin, CY | 1 |
| Shi, XK | 1 |
| Du, B | 1 |
| Xiao, HT | 1 |
| Fan, BM | 1 |
| Bian, ZX | 1 |
| Kadayat, TM | 2 |
| Banskota, S | 2 |
| Gurung, P | 2 |
| Bist, G | 2 |
| Thapa Magar, TB | 1 |
| Shrestha, A | 2 |
| Kim, JA | 3 |
| Lee, ES | 2 |
| Magar, TBT | 1 |
| Karmacharya, U | 1 |
| Regmi, SC | 1 |
| Awasthi, BP | 1 |
| Chaudhary, P | 1 |
| Kim, YE | 1 |
| Lee, IH | 1 |
| Nam, TG | 1 |
| Jeong, BS | 1 |
| Casimiro-Garcia, A | 1 |
| Allais, C | 1 |
| Brennan, A | 1 |
| Choi, C | 1 |
| Dower, G | 1 |
| Farley, KA | 1 |
| Fleming, M | 1 |
| Flick, A | 1 |
| Frisbie, RK | 1 |
| Hall, J | 1 |
| Hepworth, D | 1 |
| Jones, H | 1 |
| Knafels, JD | 1 |
| Kortum, S | 1 |
| Lovering, FE | 1 |
| Mathias, JP | 1 |
| Mohan, S | 1 |
| Morgan, PM | 1 |
| Parng, C | 1 |
| Parris, K | 1 |
| Pullen, N | 1 |
| Schlerman, F | 1 |
| Stansfield, J | 1 |
| Strohbach, JW | 1 |
| Vajdos, FF | 1 |
| Vincent, F | 1 |
| Wang, H | 2 |
| Wang, X | 1 |
| Webster, R | 1 |
| Wright, SW | 1 |
| Xia, P | 1 |
| Hou, T | 1 |
| Ma, M | 1 |
| Li, S | 1 |
| Jin, H | 1 |
| Luo, X | 1 |
| Li, J | 1 |
| Geng, F | 1 |
| Li, B | 1 |
| Yaghoubi, A | 1 |
| Amel Jamehdar, S | 1 |
| Reza Akbari Eidgahi, M | 1 |
| Ghazvini, K | 1 |
| Murad, H | 1 |
| Ahmed, O | 1 |
| Alqurashi, T | 1 |
| Hussien, M | 1 |
| Yilmaz, A | 1 |
| Uckaya, F | 1 |
| Bayindir, N | 1 |
| Guler, EM | 1 |
| Toprak, A | 1 |
| Kocyigit, A | 1 |
| Esrefoglu, M | 1 |
| Topcu, G | 1 |
| Li, L | 1 |
| Wang, Y | 2 |
| Zhao, L | 1 |
| Ye, G | 1 |
| Shi, F | 1 |
| Li, Y | 1 |
| Zou, Y | 1 |
| Song, X | 1 |
| Zhao, X | 1 |
| Yin, Z | 1 |
| Wu, X | 3 |
| Li, W | 1 |
| Tang, H | 1 |
| Salem, GA | 3 |
| Mohamed, AA | 3 |
| Ghonimi, WAM | 3 |
| Abdallah, HM | 4 |
| Rhouma, NR | 3 |
| Ali, RI | 3 |
| Taha, M | 1 |
| Elazab, ST | 1 |
| Abdelbagi, O | 1 |
| Saati, AA | 1 |
| Babateen, O | 1 |
| Baokbah, TAS | 1 |
| Qusty, NF | 1 |
| Mahmoud, ME | 1 |
| Ibrahim, MM | 1 |
| Badawy, AM | 1 |
| Jaafar, FR | 1 |
| Abu-Raghif, A | 1 |
| Wang, ZG | 1 |
| Ying, XG | 1 |
| Gao, P | 1 |
| Wang, CL | 1 |
| Wang, YF | 1 |
| Yu, XW | 1 |
| Chen, J | 1 |
| Wang, B | 1 |
| Luo, HY | 1 |
| de Assis, POA | 1 |
| Guerra, GCB | 1 |
| Araújo, DFS | 1 |
| de Andrade, LFLI | 1 |
| de Araújo, AA | 1 |
| de Araújo, RF | 1 |
| de Carvalho, TG | 1 |
| de Souza, MFV | 1 |
| Borges, GDSC | 1 |
| Lima, MDS | 1 |
| Rolim, FRL | 1 |
| Rodrigues, RAV | 1 |
| Queiroga, RCRDE | 1 |
| Jeong, S | 3 |
| Lee, H | 4 |
| Kim, S | 4 |
| Ju, S | 3 |
| Kim, W | 3 |
| Cho, H | 2 |
| Kim, HY | 1 |
| Heo, G | 1 |
| Im, E | 1 |
| Yoo, JW | 4 |
| Yoon, IS | 3 |
| Jung, Y | 5 |
| Xie, Q | 1 |
| Zhang, Y | 1 |
| Ma, W | 1 |
| Ning, K | 1 |
| Xiang, JY | 1 |
| Cui, J | 1 |
| Xiang, H | 1 |
| Yousefi-Ahmadipour, A | 2 |
| Ebrahimi-Barough, S | 2 |
| Niknia, S | 1 |
| Allahverdi, A | 2 |
| Mirzahosseini-Pourranjbar, A | 1 |
| Tashakori, M | 1 |
| Khajouee Ravari, S | 1 |
| Asadi, F | 1 |
| Heidari Barchi Nezhad, R | 1 |
| Lotfibakhshaiesh, N | 1 |
| Mirzaei, MR | 2 |
| Wang, Z | 1 |
| Liang, Y | 1 |
| Yu, J | 1 |
| Zhang, D | 1 |
| Ren, L | 1 |
| Zhang, Z | 1 |
| Liu, Y | 2 |
| Liu, L | 2 |
| Tang, Z | 1 |
| Dong, JY | 1 |
| Xia, KJ | 1 |
| Liang, W | 1 |
| Liu, LL | 1 |
| Yang, F | 1 |
| Fang, XS | 1 |
| Xiong, YJ | 1 |
| Wang, L | 2 |
| Zhou, ZJ | 1 |
| Li, CY | 1 |
| Zhang, WD | 1 |
| Wang, JY | 1 |
| Chen, DP | 1 |
| Lin, G | 1 |
| Li, M | 2 |
| Xu, N | 1 |
| Wu, Y | 1 |
| Zhang, Q | 2 |
| Cai, J | 1 |
| Gao, C | 1 |
| Su, Z | 1 |
| Park, S | 1 |
| Min, DS | 1 |
| Zhang, J | 1 |
| Cao, L | 1 |
| Sun, Y | 1 |
| Qing, DG | 1 |
| Xu, XQ | 1 |
| Wang, JC | 1 |
| Si, JY | 1 |
| Li, N | 1 |
| Morsy, MA | 1 |
| Khalaf, HM | 1 |
| Rifaai, RA | 1 |
| Bayoumi, AMA | 1 |
| Khalifa, EMMA | 1 |
| Ibrahim, YF | 1 |
| Murugan, R | 1 |
| Saravanan, S | 1 |
| Parimelazhagan, T | 1 |
| Han, KH | 1 |
| Park, JM | 1 |
| Jeong, M | 1 |
| Han, YM | 1 |
| Go, EJ | 1 |
| Park, J | 1 |
| Kim, H | 2 |
| Han, JG | 1 |
| Kwon, O | 1 |
| Hahm, KB | 1 |
| Valcheva-Kuzmanova, S | 1 |
| Kuzmanov, A | 1 |
| Kuzmanova, V | 1 |
| Tzaneva, M | 1 |
| Kim, D | 2 |
| Zhao, J | 1 |
| Zhao, Y | 1 |
| Zong, S | 1 |
| Tian, Y | 1 |
| Chen, S | 1 |
| Liu, H | 1 |
| Jing, X | 1 |
| Sun, B | 1 |
| Sun, T | 1 |
| Yang, C | 1 |
| Rashidian, A | 1 |
| Farsinejad, A | 1 |
| PourMohammadi-Nejad, F | 1 |
| Ghazi-Khansari, M | 1 |
| Ai, J | 1 |
| Shirian, S | 1 |
| Saremi, J | 1 |
| Abdallah, DM | 1 |
| Lentzen, G | 1 |
| Marín, M | 1 |
| Giner, RM | 1 |
| Ríos, JL | 1 |
| Recio, Mdel C | 1 |
| Suneela, D | 1 |
| Gaurav, V | 1 |
| Himanshu, R | 1 |
| Mączyński, M | 1 |
| Janus, M | 1 |
| Mularek-Kubzdela, T | 1 |
| Grajek, S | 1 |
| Zhou, Y | 1 |
| Ruan, Z | 1 |
| Zhou, X | 1 |
| Huang, X | 1 |
| Li, H | 1 |
| Zhang, C | 1 |
| Liu, S | 1 |
| Deng, Z | 1 |
| Wu, G | 1 |
| Yin, Y | 1 |
| Quaglio, AE | 2 |
| Castilho, AC | 2 |
| Di Stasi, LC | 7 |
| Murad, HA | 1 |
| Ali, SS | 1 |
| Kandula, M | 1 |
| Sunil Kumar, KB | 1 |
| Palanichamy, S | 1 |
| Rampal, A | 1 |
| Luchini, AC | 3 |
| Rodrigues-Orsi, P | 1 |
| Cestari, SH | 1 |
| Seito, LN | 2 |
| Witaicenis, A | 4 |
| Pellizzon, CH | 2 |
| Prakash, A | 1 |
| Medhi, B | 1 |
| Avti, PK | 1 |
| Saikia, UN | 1 |
| Pandhi, P | 1 |
| Khanduja, KL | 1 |
| Pohlmann, A | 1 |
| Tilling, LC | 1 |
| Robinson, A | 1 |
| Woolmer, O | 1 |
| McCleary, S | 1 |
| Kruidenier, L | 1 |
| Warnock, LC | 1 |
| Lewis, HD | 1 |
| Hobson, AR | 1 |
| James, MF | 1 |
| Martínez-Augustin, O | 2 |
| López-Posadas, R | 2 |
| González, R | 1 |
| Suárez, MD | 2 |
| Zarzuelo, A | 3 |
| Sánchez de Medina, F | 2 |
| de Oliveira, DM | 1 |
| Gomes, JC | 1 |
| Philip, AK | 1 |
| Dabas, S | 1 |
| Pathak, K | 1 |
| Lee, IA | 1 |
| Bae, EA | 1 |
| Lee, JH | 1 |
| Ahn, YT | 1 |
| Huh, CS | 1 |
| Kim, DH | 2 |
| Kim, JM | 1 |
| Kang, HW | 1 |
| Cha, MY | 1 |
| Yoo, D | 1 |
| Kim, N | 1 |
| Kim, IK | 1 |
| Ku, J | 1 |
| Ma, SH | 1 |
| Jung, HC | 1 |
| Song, IS | 2 |
| Kim, JS | 1 |
| Jamontt, JM | 1 |
| Molleman, A | 1 |
| Pertwee, RG | 1 |
| Parsons, ME | 1 |
| Zhao, W | 1 |
| Song, L | 1 |
| Hongzhu, D | 1 |
| Cho, JY | 1 |
| Chi, SG | 1 |
| Chun, HS | 1 |
| Jiang, GL | 1 |
| Im, WB | 1 |
| Donde, Y | 1 |
| Wheeler, LA | 1 |
| Fruet, AC | 1 |
| Salem, L | 1 |
| Joh, EH | 1 |
| Lohman, RJ | 1 |
| Cotterell, AJ | 1 |
| Suen, J | 1 |
| Do, AT | 1 |
| Vesey, DA | 1 |
| Fairlie, DP | 1 |
| Hiruma-Lima, CA | 1 |
| Felisbino, SL | 1 |
| Garrido-Mesa, N | 1 |
| Utrilla, P | 1 |
| Gálvez, J | 2 |
| Sha, T | 1 |
| Igaki, K | 1 |
| Yamasaki, M | 1 |
| Watanabe, T | 1 |
| Tsuchimori, N | 1 |
| Zeng, Z | 1 |
| Zhan, L | 1 |
| Liao, H | 1 |
| Chen, L | 1 |
| Lv, X | 1 |
| Taccari, E | 1 |
| Spada, S | 1 |
| Giuliani, A | 1 |
| Riccieri, V | 1 |
| Sorgi, ML | 1 |
| Pecorella, I | 1 |
| Onetti Muda, A | 1 |
| Kinoshita, K | 1 |
| Sato, K | 1 |
| Hori, M | 1 |
| Ozaki, H | 1 |
| Karaki, H | 1 |
| Hollerweger, A | 1 |
| Macheiner, P | 1 |
| Brunner, W | 1 |
| Mukherjee, S | 1 |
| Tubaro, E | 1 |
| Belogi, L | 1 |
| Mezzadri, CM | 1 |
| Bettelli, E | 1 |
| MORRISON, LM | 2 |
| ROTA, L | 1 |
| SELTZER, JG | 1 |
| MANGENEY, L | 1 |
| EVANS, RS | 1 |
| FORD, WP | 1 |
| CHAPUT, Y | 1 |
| JUNG, KH | 1 |
| BARON, JH | 1 |
| CONNELL, AM | 1 |
| LENNARD-JONES, JE | 2 |
| JONES, FA | 2 |
| LANDA, L | 1 |
| TRUELOVE, SC | 1 |
| WATKINSON, G | 2 |
| DRAPER, G | 1 |
| PANITZ, F | 1 |
| BOETTIGER, LE | 1 |
| ENGSTEDT, L | 1 |
| LAGERCRANTZ, R | 1 |
| NYBERG, A | 1 |
| THORNTON, GH | 1 |
| PIEGARI, MN | 1 |
| FRIZZERA, MG | 1 |
| KEHOE, EL | 1 |
| NEWCOMER, KL | 1 |
| SVARTZ, N | 1 |
| WITTMAN, I | 1 |
| PREISICH, P | 1 |
| ANTHONISEN, P | 1 |
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| KORELITZ, BI | 2 |
| ANDERSEN, D | 1 |
| FISCHERMANN, K | 1 |
| ROSENBECK-HANSEN, J | 1 |
| IVERSEN, P | 1 |
| MARNER, IL | 1 |
| MOSBECH, J | 1 |
| RANLOV, P | 1 |
| SKOUBY, A | 1 |
| SPRECHLER, M | 1 |
| WINKLER, K | 1 |
| ZACHARIAE, F | 1 |
| MICHENER, WM | 1 |
| BROWN, CH | 1 |
| TURNBULL, RB | 1 |
| GARDNER, MD | 1 |
| BARGEN, JA | 2 |
| DICK, AP | 1 |
| GRAYSON, MJ | 1 |
| CARPENTER, RG | 1 |
| PETRIE, A | 1 |
| VOSSE-MATAGNE, G | 1 |
| O'SULLIVAN, PM | 1 |
| STAUFFER, MH | 1 |
| SAUER, WG | 1 |
| DEARING, WH | 1 |
| BAGGENSTOSS, AH | 1 |
| WALTHER, M | 1 |
| BEEKEN, WL | 1 |
| LONGMORE, AJ | 1 |
| MOERTEL, CG | 1 |
| MacMaster, JF | 1 |
| Dambach, DM | 1 |
| Lee, DB | 1 |
| Berry, KK | 1 |
| Qiu, Y | 1 |
| Zusi, FC | 1 |
| Burke, JR | 1 |
| Kim, HH | 1 |
| Kong, H | 1 |
| Choi, B | 1 |
| Yang, Y | 1 |
| Kim, Y | 1 |
| Ballester, I | 1 |
| Daddaoua, A | 1 |
| Nieto, A | 1 |
| Kohno, H | 1 |
| Suzuki, R | 1 |
| Yasui, Y | 1 |
| Miyamoto, S | 1 |
| Wakabayashi, K | 1 |
| Tanaka, T | 1 |
| Gallone, L | 1 |
| Olmi, L | 1 |
| Frühmorgen, P | 1 |
| Demling, L | 1 |
| Bartnik, W | 1 |
| Shorter, RG | 1 |
| Sharp, ME | 1 |
| Wallace, SM | 1 |
| Hindmarsh, KW | 1 |
| Brown, MA | 1 |
| Werlin, SL | 1 |
| Chusid, MJ | 1 |
| Caya, J | 1 |
| Oechler, HW | 1 |
| Krook, A | 1 |
| Järnerot, G | 4 |
| Danielsson, D | 1 |
| Into-Malmberg, MB | 1 |
| Esbjörner, E | 1 |
| Longstreth, GF | 2 |
| Green, R | 2 |
| Norris, AA | 1 |
| Lewis, AJ | 1 |
| Zeitlin, IJ | 1 |
| Hudson, E | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prevalence of Cytomegalovirus, Epstein Barr Virus and Human Herpes 6 Virus DNA in Intestinal Mucosa of Patients With Inflammatory Bowel Disease[NCT00222378] | 129 participants (Actual) | Observational | 2005-04-30 | Completed | |||
| Relevance of Valganciclovir in Recurrent Bouts of Cryptogenic Inflammatory Bowel Diseases With an Infection by Cytomegalovirus[NCT00237653] | Phase 3 | 40 participants (Anticipated) | Interventional | 2004-02-29 | Terminated (stopped due to difficulty to include patients) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 reviews available for sulfasalazine and Colitis
| Article | Year |
|---|---|
[NONSPECIFIC HEMORRHAGIC PROCTOCOLITIC (ULCERATIVE COLITIS AND HEMORRHAGIC PROCTITIS): MEDICAL DIAGNOSIS AND TREATMENT].
Topics: Adrenal Cortex Hormones; Biopsy; Colitis; Colitis, Ulcerative; Cytodiagnosis; Diagnosis; Gastrointes | 1964 |
Management of acute colitis.
Topics: Acute Disease; Colitis; Diagnosis, Differential; Humans; Prednisolone; Radiography; Sigmoidoscopy; S | 1984 |
Collagenous and lymphocytic colitis: subject review and therapeutic alternatives.
Topics: Algorithms; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Colitis; | 1995 |
Collagenous colitis: a cause of chronic diarrhea.
Topics: Age Factors; Barium Sulfate; Biopsy; Chronic Disease; Colitis; Collagen Diseases; Diagnosis, Differe | 1993 |
Collagenous colitis in children.
Topics: Child; Chronic Disease; Colitis; Collagen; Female; Humans; Intestinal Mucosa; Recurrence; Sulfasalaz | 1993 |
[The local therapy of distal colitis and ulcerative proctitis].
Topics: Administration, Rectal; Aminosalicylic Acids; Colitis; Colitis, Ulcerative; Cromolyn Sodium; Fatty A | 1993 |
[Lymphocytic colitis: hypopotassemia as a complication and an association with toxic multinodular goiter].
Topics: Acute Disease; Chronic Disease; Colitis; Diagnosis, Differential; Diarrhea; Female; Gastrointestinal | 2000 |
Oral 5-aminosalicyclic acid in children with colonic chronic inflammatory bowel disease: clinical and pharmacokinetic experience.
Topics: Administration, Oral; Adolescent; Aminosalicylic Acids; Chronic Disease; Colitis; Drug Tolerance; Fe | 1989 |
Collagenous colitis and rheumatoid arthritis with response to sulfasalazine. A case report and review of the literature.
Topics: Aged; Arthritis, Rheumatoid; Colitis; Collagen Diseases; Colonoscopy; Humans; Male; Sulfasalazine | 1987 |
Collagenous enterocolitis: a case of collagenous colitis with involvement of the small intestine.
Topics: Aged; Colitis; Collagen; Colon; Colonoscopy; Duodenum; Female; Humans; Intestinal Mucosa; Intestine, | 1988 |
Collagenous colitis with rapid response to sulphasalazine.
Topics: Adult; Colitis; Collagen Diseases; Colon; Female; Humans; Sulfasalazine | 1988 |
[What is secured in the therapy of chronic inflammatory colonic diseases?].
Topics: Administration, Topical; Amebiasis; Azathioprine; Chronic Disease; Colitis; Colitis, Ulcerative; Col | 1974 |
[The treatment of generalized and localized ulcerative and granulomatous colitis].
Topics: Adrenal Cortex Hormones; Adult; Colectomy; Colitis; Colitis, Ulcerative; Female; Humans; Male; Middl | 1967 |
6 trials available for sulfasalazine and Colitis
| Article | Year |
|---|---|
On the efficacy of ready-made-up commercially available salicylazosulphapyridine enemas in the treatment of proctitis, proctosigmoiditis and ulcerative colitis involving rectum, sigmoid and descending colon.
Topics: Administration, Oral; Adult; Aged; Clinical Trials as Topic; Colitis; Colitis, Ulcerative; Double-Bl | 1980 |
Desensitization to sulfasalazine after hypersensitivity reactions in patients with inflammatory bowel disease.
Topics: Clinical Trials as Topic; Colitis; Colitis, Ulcerative; Crohn Disease; Desensitization, Immunologic; | 1984 |
Response to treatment of microscopic colitis.
Topics: Aminosalicylic Acids; Colitis; Colon; Diarrhea; Drug Therapy, Combination; Eosinophils; Female; Foll | 1994 |
Effects of gum resin of Boswellia serrata in patients with chronic colitis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Colitis; Female; Gastrointestinal A | 2001 |
Double-blind comparison of the effectiveness of azathioprine and sulfasalazine in idiopathic proctocolitis. Preliminary report.
Topics: Acute Disease; Adolescent; Adult; Aged; Azathioprine; Biopsy; Clinical Trials as Topic; Colitis; Dru | 1975 |
Salicylazosulfapyridine in inflammatory bowel disease.
Topics: Biological Availability; Clinical Trials as Topic; Colitis; Drug Evaluation; Humans; Sulfasalazine | 1975 |
207 other studies available for sulfasalazine and Colitis
| Article | Year |
|---|---|
Novel dual inhibitors of 5-lipoxygenase and thromboxane A2 synthetase: synthesis and structure-activity relationships of 3-pyridylmethyl-substituted 2-amino-6-hydroxybenzothiazole derivatives.
Topics: Animals; Blood Platelets; Cells, Cultured; Colitis; Dinoprostone; Disease Models, Animal; Humans; Le | 1994 |
Synthesis, kinetic studies and pharmacological evaluation of mutual azo prodrug of 5-aminosalicylic acid for colon-specific drug delivery in inflammatory bowel disease.
Topics: Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon; Female; Male | 2007 |
Colon-specific, mutual azo prodrug of 5-aminosalicylic acid with L-tryptophan: synthesis, kinetic studies and evaluation of its mitigating effect in trinitrobenzenesulfonic acid-induced colitis in rats.
Topics: Animals; Azo Compounds; Body Weight; Colitis; Kinetics; Mesalamine; Molecular Structure; Organ Size; | 2007 |
Colon-specific mutual amide prodrugs of 4-aminosalicylic acid for their mitigating effect on experimental colitis in rats.
Topics: Aminosalicylic Acids; Animals; Colitis; Colon; Drug Delivery Systems; Drug Stability; Drug-Related S | 2009 |
Synthesis, kinetic studies and pharmacological evaluation of mutual azo prodrugs of 5-aminosalicylic acid for colon-specific drug delivery in inflammatory bowel disease.
Topics: Aminosalicylic Acids; Animals; Arthritis; Colitis; Colon; Female; Inflammatory Bowel Diseases; Male; | 2009 |
Bacteria-Derived Compatible Solutes Ectoine and 5α-Hydroxyectoine Act as Intestinal Barrier Stabilizers to Ameliorate Experimental Inflammatory Bowel Disease.
Topics: Amino Acids, Diamino; Animals; Bacteria; Colitis; Colon; Egypt; Glutathione; Humans; Inflammatory Bo | 2015 |
Anti-inflammatory Actions of (+)-3'α-Angeloxy-4'-keto-3',4'-dihydroseselin (Pd-Ib) against Dextran Sulfate Sodium-Induced Colitis in C57BL/6 Mice.
Topics: Animals; Anti-Inflammatory Agents; Bupleurum; Colitis; Colon; Coumarins; Cytokines; Dextran Sulfate; | 2016 |
Discovery and structure-activity relationship studies of 2-benzylidene-2,3-dihydro-1H-inden-1-one and benzofuran-3(2H)-one derivatives as a novel class of potential therapeutics for inflammatory bowel disease.
Topics: Animals; Benzofurans; Colitis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discov | 2017 |
Synthesis and biological evaluation of pyridine-linked indanone derivatives: Potential agents for inflammatory bowel disease.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Colitis; Dise | 2018 |
Synthesis and activity of N-(5-hydroxy-3,4,6-trimethylpyridin-2-yl)acetamide analogues as anticolitis agents via dual inhibition of TNF-α- and IL-6-induced cell adhesions.
Topics: Acetamides; Animals; Cell Adhesion; Colitis; Dose-Response Relationship, Drug; Interleukin-6; Molecu | 2021 |
Discovery of a Series of Pyrimidine Carboxamides as Inhibitors of Vanin-1.
Topics: Amidohydrolases; Animals; Colitis; Crystallography, X-Ray; Dextran Sulfate; Dogs; Drug Discovery; Fe | 2022 |
Konjac oligosaccharides attenuate DSS-induced ulcerative colitis in mice: mechanistic insights.
Topics: Amorphophallus; Animals; Colitis; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; Disease Mo | 2022 |
Evaluation of the therapeutic effect of melittin peptide on the ulcerative colitis mouse model.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Mod | 2022 |
Olmesartan medoxomil self-microemulsifying drug delivery system reverses apoptosis and improves cell adhesion in trinitrobenzene sulfonic acid-induced colitis in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cadherins; Caspase 3; Cell Adhesion; Colitis; Crohn | 2022 |
Comparing healing effect against ulcerative colitis and toxicological effects of Rosmarinus officinalis: A comprehensive in vivo study of an edible plant in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Humans; Plant Extracts; Plants, Edible; Ra | 2022 |
Sanhuang xiexin decoction ameliorates secondary liver injury in DSS-induced colitis involve regulating inflammation and bile acid metabolism.
Topics: Animals; Bile Acids and Salts; Colitis; Colitis, Ulcerative; Cytokines; Dextran Sulfate; Disease Mod | 2022 |
The synbiotic mixture of Bacillus licheniformis and Saccharomyces cerevisiae extract aggravates dextran sulfate sodium induced colitis in rats.
Topics: Animals; Bacillus licheniformis; Colitis; Dextran Sulfate; Humans; Rats; Rats, Sprague-Dawley; Roden | 2022 |
The synbiotic mixture of Bacillus licheniformis and Saccharomyces cerevisiae extract aggravates dextran sulfate sodium induced colitis in rats.
Topics: Animals; Bacillus licheniformis; Colitis; Dextran Sulfate; Humans; Rats; Rats, Sprague-Dawley; Roden | 2022 |
The synbiotic mixture of Bacillus licheniformis and Saccharomyces cerevisiae extract aggravates dextran sulfate sodium induced colitis in rats.
Topics: Animals; Bacillus licheniformis; Colitis; Dextran Sulfate; Humans; Rats; Rats, Sprague-Dawley; Roden | 2022 |
The synbiotic mixture of Bacillus licheniformis and Saccharomyces cerevisiae extract aggravates dextran sulfate sodium induced colitis in rats.
Topics: Animals; Bacillus licheniformis; Colitis; Dextran Sulfate; Humans; Rats; Rats, Sprague-Dawley; Roden | 2022 |
The synbiotic mixture of Bacillus licheniformis and Saccharomyces cerevisiae extract aggravates dextran sulfate sodium induced colitis in rats.
Topics: Animals; Bacillus licheniformis; Colitis; Dextran Sulfate; Humans; Rats; Rats, Sprague-Dawley; Roden | 2022 |
The synbiotic mixture of Bacillus licheniformis and Saccharomyces cerevisiae extract aggravates dextran sulfate sodium induced colitis in rats.
Topics: Animals; Bacillus licheniformis; Colitis; Dextran Sulfate; Humans; Rats; Rats, Sprague-Dawley; Roden | 2022 |
The synbiotic mixture of Bacillus licheniformis and Saccharomyces cerevisiae extract aggravates dextran sulfate sodium induced colitis in rats.
Topics: Animals; Bacillus licheniformis; Colitis; Dextran Sulfate; Humans; Rats; Rats, Sprague-Dawley; Roden | 2022 |
The synbiotic mixture of Bacillus licheniformis and Saccharomyces cerevisiae extract aggravates dextran sulfate sodium induced colitis in rats.
Topics: Animals; Bacillus licheniformis; Colitis; Dextran Sulfate; Humans; Rats; Rats, Sprague-Dawley; Roden | 2022 |
The synbiotic mixture of Bacillus licheniformis and Saccharomyces cerevisiae extract aggravates dextran sulfate sodium induced colitis in rats.
Topics: Animals; Bacillus licheniformis; Colitis; Dextran Sulfate; Humans; Rats; Rats, Sprague-Dawley; Roden | 2022 |
Phytochemical analysis of Origanum majorana L. extract and investigation of its antioxidant, anti-inflammatory and immunomodulatory effects against experimentally induced colitis downregulating Th17 cells.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Colitis, Ulcerative; Colon; Glutathione; M | 2023 |
Comparative treatment of Sulfasalazine+Ezetimibe combination and Sulfasalazine in a rat model with induced colitis.
Topics: Acetates; Animals; Biomarkers; Colitis; Colitis, Ulcerative; Colon; E-Selectin; NF-kappa B; Quality | 2023 |
Anti-Inflammatory Activity of a Peptide from Skipjack (
Topics: Animals; Animals, Genetically Modified; Anti-Inflammatory Agents; Colitis; Colitis, Ulcerative; Colo | 2019 |
Intestinal anti-inflammatory activity of xique-xique (Pilosocereus gounellei A. Weber ex K. Schum. Bly. Ex Rowl) juice on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Cactaceae; Colitis; Cytokines; Dose-Response Relatio | 2019 |
5-Aminosalicylic Acid Azo-Coupled with a GPR109A Agonist Is a Colon-Targeted Anticolitic Codrug with a Reduced Risk of Skin Toxicity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Chromatography, Liquid; Colitis; | 2020 |
Combination of probiotics with different functions alleviate DSS-induced colitis by regulating intestinal microbiota, IL-10, and barrier function.
Topics: Animals; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Drugs, Chinese Herbal; Dysbiosis; | 2020 |
Therapeutic effects of combination of platelet lysate and sulfasalazine administration in TNBS-induced colitis in rat.
Topics: Animals; Apoptosis; Blood Platelets; Colitis; Combined Modality Therapy; Cytokines; Disease Models, | 2020 |
Guchang Zhixie Wan protects mice against dextran sulfate sodium-induced colitis through modulating the gut microbiota in colon.
Topics: Animals; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Dose-Response Relations | 2020 |
Ginsenoside Rb1 alleviates colitis in mice via activation of endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 signaling pathway.
Topics: Animals; Apoptosis; Cell Line; Colitis; Colon; Cytokines; Dextran Sulfate; Endoplasmic Reticulum; Gi | 2021 |
Anti-Inflammatory Effects of
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Azathioprine; Chromatography, Liquid; Colitis; Colitis | 2020 |
Preparation and Evaluation of Colon-Targeted Prodrugs of the Microbial Metabolite 3-Indolepropionic Acid as an Anticolitic Agent.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Colitis; Colon; Dinitrofluorobenzene; Disea | 2021 |
The Regulatory Effects of Licochalcone A on the Intestinal Epithelium and Gut Microbiota in Murine Colitis.
Topics: Animals; Chalcones; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Ga | 2021 |
Canagliflozin, an SGLT-2 inhibitor, ameliorates acetic acid-induced colitis in rats through targeting glucose metabolism and inhibiting NOX2.
Topics: Acetic Acid; Animals; Antioxidants; Canagliflozin; Colitis; Colon; Glucose; Male; NADPH Oxidase 2; O | 2021 |
Study of intestinal anti-inflammatory activity of Phoenix loureiroi Kunth (Arecaceae) fruit.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arecaceae; Colitis; Fruit; India; Inflammatory Bowe | 2017 |
Heme Oxygenase-1 Induction and Anti-inflammatory Actions of
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Atractylodes; Colitis; Cyclooxygenase 2; Dextran S | 2017 |
Aronia melanocarpa fruit juice ameliorates the symptoms of inflammatory bowel disease in TNBS-induced colitis in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Disease Models, Animal; Fruit and Vegetabl | 2018 |
Therapeutic switching of sulpiride, an anti-psychotic and prokinetic drug, to an anti-colitic drug using colon-specific drug delivery.
Topics: Animals; Benzamides; Colitis; Colon; Dinitrofluorobenzene; Disease Models, Animal; Dose-Response Rel | 2019 |
Therapeutic effects of lentinan on inflammatory bowel disease and colitis-associated cancer.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Azoxymethane; Carcinoembryonic Antigen; | 2019 |
Combination therapy of mesenchymal stromal cells and sulfasalazine attenuates trinitrobenzene sulfonic acid induced colitis in the rat: The S1P pathway.
Topics: Animals; bcl-2-Associated X Protein; Colitis; Colon; Gastrointestinal Agents; Gene Expression Regula | 2019 |
Colon-Targeted Delivery Facilitates the Therapeutic Switching of Sofalcone, a Gastroprotective Agent, to an Anticolitic Drug via Nrf2 Activation.
Topics: Administration, Oral; Amino Acids, Acidic; Animals; Anti-Ulcer Agents; Chalcones; Colitis; Dinitrofl | 2019 |
Novel effects of ectoine, a bacteria-derived natural tetrahydropyrimidine, in experimental colitis.
Topics: Amino Acids, Diamino; Animals; Body Weight; Colitis; Colon; Dinoprostone; Disease Models, Animal; Do | 2013 |
Protective effect of apocynin in a mouse model of chemically-induced colitis.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Colitis; Colon; Cyclooxygenase 2; Cyclooxygenase 2 | 2013 |
Design and development of novel azo prodrugs using various permutations and combinations of 5- and 4-aminosalicylic acids for inflammatory bowel disease: a colon-targeted approach.
Topics: Aminosalicylic Acid; Animals; Azo Compounds; Colitis; Colon; Drug Design; Female; Humans; Inflammato | 2013 |
Myocarditis and pericarditis in the course of colitis ulcerosa.
Topics: Adult; Colitis; Electrocardiography; Humans; Male; Myocarditis; Pericarditis; Ramipril; Sulfasalazin | 2014 |
A diet with lactosucrose supplementation ameliorates trinitrobenzene sulfonic acid-induced colitis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon; Disease Models, Animal; Female; Ga | 2015 |
Experimental evidence of MAP kinase gene expression on the response of intestinal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Azathioprine; Colitis; Enzyme Induction; Gene Expression; Male; M | 2015 |
Experimental evidence of heparanase, Hsp70 and NF-κB gene expression on the response of anti-inflammatory drugs in TNBS-induced colonic inflammation.
Topics: Animals; Anti-Inflammatory Agents; Azathioprine; Biomarkers; Colitis; Colon; Cytokines; Gene Express | 2015 |
Mentha longifolia protects against acetic-acid induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Colitis; Colon; Cyclohexan | 2016 |
Discovery and preclinical development of a novel prodrug conjugate of mesalamine with eicosapentaenoic acid and caprylic acid for the treatment of inflammatory bowel diseases.
Topics: Aminosalicylic Acids; Animals; Caprylates; Colitis; Colon; Dextran Sulfate; Drug Discovery; Drug Eva | 2016 |
Intestinal anti-inflammatory activity of coumarin and 4-hydroxycoumarin in the trinitrobenzenesulphonic acid model of rat colitis.
Topics: 4-Hydroxycoumarins; Acute Disease; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Chronic | 2008 |
Effect of different doses of Manuka honey in experimentally induced inflammatory bowel disease in rats.
Topics: Analysis of Variance; Animals; Antioxidants; Colitis; Colon; Disease Models, Animal; Glutathione; Ho | 2008 |
Progression and variability of TNBS colitis-associated inflammation in rats assessed by contrast-enhanced and T2-weighted MRI.
Topics: Anesthetics, Inhalation; Animals; Colitis; Colon; Contrast Media; Disease Models, Animal; Disease Pr | 2009 |
Genomic analysis of sulfasalazine effect in experimental colitis is consistent primarily with the modulation of NF-kappaB but not PPAR-gamma signaling.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; CHO Cells; Colitis; Cricetinae; C | 2009 |
Relationship between mast cells and the colitis with relapse induced by trinitrobenzesulphonic acid in Wistar rats.
Topics: Animals; Colitis; Colon; Gastrointestinal Agents; Histamine; Male; Mast Cells; Microscopy; Nedocromi | 2009 |
Optimized prodrug approach: a means for achieving enhanced anti-inflammatory potential in experimentally induced colitis.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Glycine; Ketoprofen; Prodrug | 2009 |
Bifidobacterium longum HY8004 attenuates TNBS-induced colitis by inhibiting lipid peroxidation in mice.
Topics: Animals; Anti-Infective Agents; Bifidobacterium; Cell Line; Colitis; Colon; Humans; Lipid Peroxidati | 2010 |
Novel guggulsterone derivative GG-52 inhibits NF-kappaB signaling in intestinal epithelial cells and attenuates acute murine colitis.
Topics: Animals; Anti-Inflammatory Agents; Cell Line, Tumor; Chemokine CCL2; Colitis; Dextran Sulfate; Epith | 2010 |
Intestinal anti-inflammatory activity of esculetin and 4-methylesculetin in the trinitrobenzenesulphonic acid model of rat colitis.
Topics: Alkaline Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Colitis; Disea | 2010 |
The effects of Delta-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis.
Topics: Animals; Cannabidiol; Colitis; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Dron | 2010 |
Amelioration of dextran sulfate sodium-induced chronic colitis by sulfasalazine salicylazosulfapyridine via reducing NF-kappaB transcription factor p65 recruitment to ICAM-1 gene promoters.
Topics: Animals; Chronic Disease; Colitis; Dextran Sulfate; DNA Fragmentation; Female; Intercellular Adhesio | 2010 |
Oral administration of docosahexaenoic acid attenuates colitis induced by dextran sulfate sodium in mice.
Topics: Acute-Phase Proteins; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body W | 2011 |
Comparison of prostaglandin E2 receptor subtype 4 agonist and sulfasalazine in mouse colitis prevention and treatment.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cell Proliferation; Colitis; Colon; D | 2010 |
Dietary polydextrose prevents inflammatory bowel disease in trinitrobenzenesulfonic acid model of rat colitis.
Topics: Alkaline Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon; Drug Interac | 2010 |
Kalopanaxsaponin A ameliorates experimental colitis in mice by inhibiting IRAK-1 activation in the NF-κB and MAPK pathways.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Cytokines; Disease Models, Animal; Dose-Response Relatio | 2011 |
Antagonism of protease-activated receptor 2 protects against experimental colitis.
Topics: Animals; Body Weight; Calcium Signaling; Colitis; Colon; Cytokines; Edema; HT29 Cells; Humans; Inden | 2012 |
Suppression of TNBS-induced colitis in rats by 4-methylesculetin, a natural coumarin: comparison with prednisolone and sulphasalazine.
Topics: Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Apoptosis; Cell Line; Colitis; Coumarins; C | 2012 |
Establishment and validation of a new semi-chronic dextran sulfate sodium-induced model of colitis in mice.
Topics: Animals; Anti-Inflammatory Agents; Antibodies; Colitis; Cytokines; Dextran Sulfate; Disease Models, | 2013 |
Curcumin improves TNBS-induced colitis in rats by inhibiting IL-27 expression via the TLR4/NF-κB signaling pathway.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Colon; Curcumin; Disease Models, Animal; Gastrointestina | 2013 |
Co-occurrence of psoriatic arthritis with collagenous colitis: clinicopathologic findings of a case.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Psoriatic; Arthrography; C | 2002 |
Decrease in activity of smooth muscle L-type Ca2+ channels and its reversal by NF-kappaB inhibitors in Crohn's colitis model.
Topics: Animals; Calcium Channels, L-Type; Colitis; Crohn Disease; Electric Conductivity; Enzyme Inhibitors; | 2003 |
Suspicion of microscopic colitis raised by sonographic examination.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidiarrheals; Budesonide; Colit | 2003 |
Diarrhea associated with lansoprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Colitis; Colonoscopy; Diarrhea; Gastroin | 2003 |
Impact on the bowel of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug.
Topics: Acetic Acid; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon; | 2003 |
Response of ulcerative colitis to therapy with salicylazosulfapyridine.
Topics: Colitis; Colitis, Ulcerative; Sulfanilamide; Sulfanilamides; Sulfasalazine; Sulfonamides | 1953 |
[Treatment of ulcerative colitis with salicylazosulfapyridine].
Topics: Colitis; Colitis, Ulcerative; Sulfanilamide; Sulfanilamides; Sulfasalazine; Sulfonamides | 1953 |
Chronic ulcerative colitis and continuous azulfidine therapy; report of a case.
Topics: Colitis; Colitis, Ulcerative; Sulfanilamide; Sulfanilamides; Sulfasalazine; Sulfonamides | 1956 |
[Treatment of ulcero-hemorrhagic rectocolitis and acute rheumatismal polyarthritis of colic origin by salicylazosulfapyridine (salazopyrin)].
Topics: Colic; Colitis; Colitis, Ulcerative; Humans; Megacolon; Proctocolitis; Rheumatic Fever; Sulfasalazin | 1957 |
Studies of the bone marrow in immunological granulocytopenia; following administration of salicylazosulfapyridine.
Topics: Agranulocytosis; Anemia, Myelophthisic; Bone Marrow; Colitis; Colitis, Ulcerative; Sulfanilamide; Su | 1958 |
[Contribution to the medical treatment of ulcerative rectocolitis with "Salazopyrin"].
Topics: Colitis; Colitis, Ulcerative; Proctocolitis; Sulfanilamide; Sulfanilamides; Sulfasalazine; Sulfonami | 1960 |
[Ulcerative colitis and its therapy, especially with azulfidine].
Topics: Colitis; Colitis, Ulcerative; Sulfanilamide; Sulfanilamides; Sulfasalazine; Sulfonamides | 1961 |
Sulphasalazine and salicylazosulphadimidine in ulcerative colitis.
Topics: Colitis; Colitis, Ulcerative; Sulfanilamide; Sulfanilamides; Sulfasalazine; Sulfonamides | 1962 |
[Chronic non-specific ulcerative colitis. Medical treatment].
Topics: Adrenal Cortex Hormones; Anatomy; Colitis; Colitis, Ulcerative; Humans; Sulfasalazine; Water-Electro | 1963 |
Comparison of corticosteroid and sulphasalazine therapy in ulcerative colitis.
Topics: Adrenal Cortex Hormones; Colitis; Colitis, Ulcerative; Humans; Sulfanilamide; Sulfanilamides; Sulfas | 1962 |
[The medical treatment of ulcerative colitis].
Topics: Adrenocorticotropic Hormone; Colitis; Colitis, Ulcerative; Cortisone; Humans; Sulfasalazine | 1962 |
AGRANULOCYTOSIS DUE TO ADMINISTRATION OF SALICYLAZOSULFAPYRADINE (AZULFIDINE).
Topics: Agranulocytosis; Colitis; Colitis, Ulcerative; Humans; Sulfasalazine; Toxicology | 1963 |
THE OCCURRENCE OF HEINZ BODIES DURING AZULFIDINE TREATMENT OF ULCERATIVE COLITIS.
Topics: Anemia; Anemia, Hemolytic; Colitis; Colitis, Ulcerative; Heinz Bodies; Humans; Statistics as Topic; | 1963 |
THE MEDICAL MANAGEMENT OF NON-SPECIFIC ULCERATIVE COLITIS.
Topics: Adrenocorticotropic Hormone; Colitis; Colitis, Ulcerative; Diet; Diet Therapy; Disease Management; H | 1963 |
[ULCERATIVE COLITIS AND SALYCYLAZOSULFAPYRIDINE].
Topics: Adrenocorticotropic Hormone; Cardiovascular Agents; Colitis; Colitis, Ulcerative; Muscle Relaxants, | 1963 |
THROMBOEMBOLIC PHENOMENA IN ULCERATIVE COLITIS. TWO CASE REPORTS.
Topics: Anemia; Anemia, Hemolytic; Autoimmune Diseases; Blood Coagulation; Chlordiazepoxide; Colitis; Coliti | 1964 |
ULCERATIVE COLITIS: CHANGES IN THE INTESTINAL WALLS AND THERAPEUTIC CONSIDERATIONS.
Topics: Adrenal Cortex Hormones; Carbon Isotopes; Colitis; Colitis, Ulcerative; Colonic Neoplasms; Mice; Neo | 1964 |
[DRUG THERAPY OF COLITIS ULCEROSA (GRAVIS)].
Topics: Adrenocorticotropic Hormone; Colitis; Colitis, Ulcerative; Enema; Gastrointestinal Hemorrhage; Human | 1964 |
ULCERATIVE COLITIS IN CHILDREN.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Child; Colitis; Colitis, Ulcerative; Cortisone | 1964 |
[MEDICAL TREATMENT OF ULCERATIVE COLITIS IN COPENHAGEN'S MUNICIPAL HOSPITALS].
Topics: Adolescent; Adrenocorticotropic Hormone; Anti-Bacterial Agents; Antibiotics, Antitubercular; Blood T | 1964 |
ULCERATIVE COLITIS IN CHILDREN. II. MEDICAL AND SURGICAL THERAPY.
Topics: Adolescent; Adrenocorticotropic Hormone; Arthritis; Child; Chloramphenicol; Colitis; Colitis, Ulcera | 1964 |
HEMOLYTIC ANEMIA SECONDARY TO SALICYLAZOSULFAPYRIDINE THERAPY.
Topics: Anemia; Anemia, Hemolytic; Blood Cell Count; Colitis; Colitis, Ulcerative; Drug Therapy; Hematocrit; | 1964 |
CONTROLLED TRIAL OF SULPHASALAZINE IN THE TREATMENT OF ULCERATIVE COLITIS.
Topics: Anemia; Anemia, Hemolytic; Biomedical Research; Colitis; Colitis, Ulcerative; Drug Therapy; Gastroin | 1964 |
[CURRENT TRENDS IN THE TREATMENT OF HEMORRHAGIC RECTOCOLITIS].
Topics: Colitis; Colitis, Ulcerative; Drug Therapy; Humans; Proctocolitis; Sulfasalazine | 1964 |
DRUGS FOR ULCERATIVE COLITIS.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Bacterial Agents; Antibiotics, Antituberc | 1964 |
THE SPECTRUM OF CHOLESTATIC HEPATIC DISEASE.
Topics: Adolescent; Alkaline Phosphatase; Aspartate Aminotransferases; Bile Duct Neoplasms; Bilirubin; Blood | 1965 |
[EXPERIENCES WITH THE COMBINED THERAPY OF ULCERATIVE COLITIS BY THE USE OF PREDNISONE RETENTION ENEMA AND SALICYLAZOSULFAPYRIDINE].
Topics: Colitis; Colitis, Ulcerative; Drug Therapy; Enema; Humans; Prednisone; Psychotherapy, Multiple; Sulf | 1964 |
MEDICAL TREATMENT OF ULCERATIVE COLITIS.
Topics: Adrenal Cortex Hormones; Colitis; Colitis, Ulcerative; Drug Therapy; Humans; Sulfasalazine | 1965 |
A comparative trial of salazopyrin, prednisone and hydrocortisone retention enemata in the out-patient treatment of left-sided colitis. Preliminary report.
Topics: Adrenal Cortex Hormones; Ambulatory Care; Colitis; Colitis, Ulcerative; Enema; Humans; Hydrocortison | 1960 |
A critical analysis of the use of salicylazosulfapyridine in chronic ulcerative colitis.
Topics: Colitis; Colitis, Ulcerative; Sulfanilamide; Sulfanilamides; Sulfasalazine; Sulfonamides | 1959 |
Results of treatment of ulcerative colitis with salicylazosulfapyridine.
Topics: Colitis; Colitis, Ulcerative; Sulfanilamide; Sulfanilamides; Sulfasalazine; Sulfonamides | 1952 |
An inhibitor of IkappaB kinase, BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium-induced colitis in mice.
Topics: Animals; Cell Adhesion Molecules; Cells, Cultured; Colitis; Dextran Sulfate; Disease Models, Animal; | 2003 |
Evaluation of 5-aminosalicyltaurine as a colon-specific prodrug of 5-aminosalicylic acid for treatment of experimental colitis.
Topics: Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressur | 2006 |
The bisphosphonate alendronate improves the damage associated with trinitrobenzenesulfonic acid-induced colitis in rats.
Topics: Administration, Oral; Alendronate; Animals; Anti-Inflammatory Agents; Body Weight; Bone Density Cons | 2007 |
Ursodeoxycholic acid versus sulfasalazine in colitis-related colon carcinogenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Diseas | 2007 |
[Ulcerative colitis and Crohn's colitis. Medical or surgical treatment].
Topics: Anti-Inflammatory Agents; Betamethasone; Colectomy; Colitis; Colitis, Ulcerative; Crohn Disease; Hum | 1980 |
[An approach to the medical management of inflammatory bowel disease (author's transl)].
Topics: Azathioprine; Colitis; Colitis, Ulcerative; Crohn Disease; Humans; Parenteral Nutrition, Total; Pred | 1981 |
Acetylator phenotype and serum levels of sulfapyridine in patients with inflammatory bowel disease.
Topics: Acetylation; Adolescent; Adult; Aged; Anti-Infective Agents; Colitis; Colitis, Ulcerative; Crohn Dis | 1981 |
Colitis in chronic granulomatous disease.
Topics: Adolescent; Colectomy; Colitis; Crohn Disease; Diagnosis, Differential; Granulomatous Disease, Chron | 1982 |
Clinical effect of metronidazole and sulfasalazine on Crohn's disease in relation to changes in the fecal flora.
Topics: Adolescent; Adult; Bacteroides; Bacteroides Infections; Child; Colitis; Crohn Disease; Enteritis; Fe | 1981 |
Placental transfer of sulphasalazine and sulphapyridine and some of its metabolites.
Topics: Colitis; Colitis, Ulcerative; Crohn Disease; Female; Humans; Infant, Newborn; Maternal-Fetal Exchang | 1981 |
Folate levels in inflammatory bowel disease.
Topics: Chronic Disease; Colitis; Folic Acid; Humans; Sulfasalazine | 1982 |
Actions of anticolitic drugs on a guinea-pig model of immune colitis.
Topics: Animals; Azathioprine; Colitis; Cromolyn Sodium; Dinitrochlorobenzene; Gastrointestinal Agents; Guin | 1982 |
Sperm size in patients with inflammatory bowel disease on sulfasalazine therapy.
Topics: Adult; Analysis of Variance; Colitis; Computers; Fertility; Humans; Infertility, Male; Male; Semen; | 1982 |
[Use of salazopyridazine in suppositories in chronic colitis].
Topics: Adult; Chronic Disease; Colitis; Colitis, Ulcerative; Drug Evaluation; Female; Gastrointestinal Moti | 1982 |
[The treatment of inflammatory diseases of the colon with salazopyrine].
Topics: Colitis; Crohn Disease; Drug Combinations; Glucosamine; Humans; Proctocolitis; Sulfasalazine | 1982 |
Microscopic colitis-a cause of chronic watery diarrhoea.
Topics: Adult; Chronic Disease; Colitis; Colon; Diarrhea; Female; Humans; Indomethacin; Male; Middle Aged; P | 1982 |
Possible teratogenicity of sulphasalazine.
Topics: Abnormalities, Drug-Induced; Adult; Colitis; Diseases in Twins; Female; Heart Defects, Congenital; H | 1983 |
Sulfasalazine-induced colitis complicating idiopathic ulcerative colitis.
Topics: Child; Colitis; Colitis, Ulcerative; Humans; Male; Sulfasalazine | 1984 |
The prophylactic effect of 5-aminosalicylic acid and salazosulphapyridine on degraded-carrageenan-induced colitis in guinea pigs.
Topics: Aminosalicylic Acids; Animals; Carrageenan; Cecum; Colitis; Delayed-Action Preparations; Drug Evalua | 1984 |
Sulfasalazine in treatment of collagenous colitis. Case report and review of the literature.
Topics: Chronic Disease; Colitis; Collagen; Colon; Female; Humans; Middle Aged; Sulfasalazine | 1984 |
Is segmental colitis a complication of diverticular disease?
Topics: Aged; Colectomy; Colitis; Diverticulum, Colon; Female; Humans; Male; Middle Aged; Sigmoid Diseases; | 1984 |
Folate status in patients receiving maintenance doses of sulfasalazine.
Topics: Colitis; Erythrocytes; Folic Acid; Folic Acid Deficiency; Humans; Sulfasalazine | 1983 |
[Methods for studying inflammatory diseases of the intestine].
Topics: Antibody Formation; Blood Protein Electrophoresis; Colitis; Crohn Disease; Drug Combinations; Glucos | 1984 |
[Appearance of sulfasalazine and sulfapyridine in breast milk and in the placental barrier as well as the effect of both substances on bilirubin binding to albumin].
Topics: Bilirubin; Colitis; Female; Fetal Blood; Humans; Infant, Newborn; Maternal-Fetal Exchange; Milk, Hum | 1981 |
[Current therapeutic possibilities in chronic inflammatory intestinal diseases].
Topics: Aminosalicylic Acids; Chronic Disease; Colitis; Colitis, Ulcerative; Crohn Disease; Drug Therapy, Co | 1995 |
Effects of zileuton, a new 5-lipoxygenase inhibitor, in experimentally induced colitis in rats.
Topics: Animals; Colitis; Colon; Eicosanoids; Hydroxyurea; Inflammatory Bowel Diseases; Leukocytes; Lipoxyge | 1993 |
[An unusual cause of chronic diarrhea: lymphocytic colitis].
Topics: Aged; Chronic Disease; Colitis; Colon; Diarrhea; Drug Combinations; Female; Glucosamine; Humans; Int | 1994 |
[Granulomatous colitis (Crohn disease) in the first year of life].
Topics: Colitis; Colon; Colonoscopy; Crohn Disease; Fiber Optic Technology; Humans; Infant; Male; Radiograph | 1993 |
[Diarrhea].
Topics: Colitis; Collagen; Diagnosis, Differential; Diarrhea; Humans; Male; Middle Aged; Sulfasalazine | 1993 |
A prospective study of the epidemiology of colitis and colon cancer in cotton-top tamarins (Saguinus oedipus).
Topics: Adenocarcinoma; Animals; Body Weight; Campylobacter Infections; Colitis; Colonic Neoplasms; Disease | 1996 |
Celiac disease, inflammatory colitis, and primary sclerosing cholangitis in a girl with Turner's syndrome.
Topics: Biopsy; Celiac Disease; Child; Cholangitis, Sclerosing; Colitis; Female; Glutens; Hormones; Humans; | 1995 |
Anticardiolipin antibodies in Crohn's disease associated with diabetes mellitus.
Topics: Anti-Inflammatory Agents; Antibodies, Anticardiolipin; Blood Glucose; Colitis; Crohn Disease; Diabet | 1996 |
Collagenous colitis: histopathology and clinical course.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antidiarrheals; Colitis; Collagen; Diarrhe | 1997 |
Collagenous colitis: a retrospective study of clinical presentation and treatment in 163 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anticholesteremic Agents; Anti | 1996 |
[A frequently used drug with fatal outcome!].
Topics: Animals; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Colitis; Dog Diseases; Dogs; | 1997 |
Effect of Z-103 on TNB-induced colitis in rats.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Carnosine; Colitis; Colon; Intestinal Mucosa; Male; Organo | 1997 |
Effects of nitric oxide synthase inhibition or sulfasalazine on the spontaneous colitis observed in HLA-B27 transgenic rats.
Topics: Animals; Animals, Genetically Modified; Body Weight; Colitis; Colon; Enzyme Inhibitors; HLA-B27 Anti | 1998 |
[Collagenous colitis: presentation of 12 cases].
Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Inflammato | 1997 |
Collagenous colitis associated with rheumatoid arthritis and anticardiolipin antibodies.
Topics: Anti-Inflammatory Agents; Antibodies, Anticardiolipin; Arthritis, Rheumatoid; Colitis; Collagen Dise | 1998 |
Enteropathic arthritis in association with collagenous colitis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis; Biopsy, Needle; Colitis; C | 1998 |
Experimental colitis induced by dextran sulphate sodium in mice: beneficial effects of sulphasalazine and olsalazine.
Topics: Aminosalicylic Acids; Animals; Colitis; Dextran Sulfate; Disease Models, Animal; Dose-Response Relat | 1998 |
5-ASA-glutamate protects rats from inflammatory bowel disease induced by intracolonic administration of trinitrobenzensulfonic acid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Colitis; Col | 1998 |
Collagenous colitis in a patient with Addison's disease: a case report.
Topics: Addison Disease; Adult; Colitis; Collagen; Colonoscopy; Diarrhea; Female; Gastrointestinal Agents; H | 1998 |
Effect of DA-6034, a derivative of flavonoid, on experimental animal models of inflammatory bowel disease.
Topics: Acetic Acid; Animals; Animals, Genetically Modified; Anti-Inflammatory Agents; Anti-Inflammatory Age | 1999 |
Repeated measurement of intestinal permeability as an assessment of colitis severity in HLA-B27 transgenic rats.
Topics: Animals; Biomarkers; Colitis; Colon; Contrast Media; Cyclosporine; Dose-Response Relationship, Drug; | 1999 |
The effect of Oren-gedoku-to on experimental colitis in rats.
Topics: Animals; Anti-Ulcer Agents; Body Weight; Colitis; Drugs, Chinese Herbal; Gastrointestinal Agents; Ma | 1999 |
Validation of a pharmacokinetic model of colon-specific drug delivery and the therapeutic effects of chitosan capsules containing 5-aminosalicylic acid on 2,4,6-trinitrobenzenesulphonic acid-induced colitis in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsules; Chitin; Chitosan; | 1999 |
Comparative study of D-002 versus sulfasalazine on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Colitis; Fatty Alcohols; Leukotriene B4; Male; Neutrophils; Rats; Rats, Spragu | 2000 |
Intestinal anti-inflammatory activity of UR-12746, a novel 5-ASA conjugate, on acute and chronic experimental colitis in the rat.
Topics: Acute Disease; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents; Aza Compounds; Chronic Disea | 2000 |
Dietary fiber fraction of germinated barley foodstuff attenuated mucosal damage and diarrhea, and accelerated the repair of the colonic mucosa in an experimental colitis.
Topics: Animals; Cellulose; Colitis; Diarrhea; Dietary Fiber; Disease Models, Animal; Fatty Acids, Volatile; | 2001 |
Oral administration of avian tumor necrosis factor antibodies effectively treats experimental colitis in rats.
Topics: Administration, Oral; Animals; Antibodies; Chickens; Colitis; Dexamethasone; Disease Models, Animal; | 2000 |
[Collagenous colitis. A study of 11 cases].
Topics: Adult; Agammaglobulinemia; Aged; Aged, 80 and over; Anemia; Anti-Inflammatory Agents; Anti-Inflammat | 2001 |
Effects of tumour necrosis factor-alpha synthesis inhibitors on rat trinitrobenzene sulphonic acid-induced chronic colitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Chronic Disease; Colitis; Colon; Disea | 2001 |
Evaluation of the anti-inflammatory effect of baicalein on dextran sulfate sodium-induced colitis in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Colitis; Dextran Sulfate; Female; Fla | 2002 |
Treatment of chronic radiation enteritis and colitis with salicylazosulfapyridine and systemic corticosteroids. A pilot study.
Topics: Aged; Colitis; Colon; Enteritis; Humans; Ileum; Intestine, Large; Intestine, Small; Middle Aged; Pil | 1976 |
[Pathogenesis and medical treatment of hemorrhagic rectocolitis].
Topics: Adrenal Cortex Hormones; Colitis; Female; France; Gastrointestinal Hemorrhage; Humans; Immunosuppres | 1976 |
[Inflammatory diseases of the colon and salazopyrine. Value of long term treatment].
Topics: Chemical Phenomena; Chemistry; Colitis; Colonic Diseases; Crohn Disease; Female; Gastrointestinal He | 1976 |
Prognosis in children with Crohn's disease.
Topics: Adolescent; Adult; Body Height; Body Weight; Child; Child, Preschool; Colitis; Crohn Disease; Female | 1978 |
[Hemorrhagic rectocolitis. Attempt at programmed therapy].
Topics: Adrenocorticotropic Hormone; Anti-Anxiety Agents; Colitis; Drug Therapy, Combination; Humans; Medaze | 1978 |
Influence of intestinal transit time on azo-reduction of salicylazosulphapyridine (Salazopyrin).
Topics: Aminosalicylic Acids; Colitis; Diarrhea; Feces; Humans; Intestinal Mucosa; Male; Sulfapyridine; Sulf | 1979 |
Induction of colitis in rats by 2-2'-azobis(2-amidinopropane) dihydrochloride.
Topics: Amidines; Aminosalicylic Acids; Animals; Benzopyrans; Colitis; Inflammation; Intestinal Mucosa; Lipi | 1992 |
[Collagenous colitis: clinical and histologic improvement after sulfasalazine and topical betamethasone].
Topics: Administration, Topical; Adult; Betamethasone; Colitis; Collagen Diseases; Female; Humans; Sulfasala | 1992 |
Effect of aminophenols (5-ASA and 4-ASA) on colonic interleukin-1 generation.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Colitis; Colon; Disease Models, Animal; Humans; | 1992 |
[Severe psychiatric disorders associated with severe acute colitis].
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antid | 1992 |
Sequential histologic evaluations in collagenous colitis. Correlations with disease behavior and sampling strategy.
Topics: Adult; Aged; Aminosalicylic Acids; Colitis; Collagen; Colon; Female; Humans; Intestinal Mucosa; Male | 1992 |
Noninfectious colitis associated with short gut syndrome in infants.
Topics: Carbohydrate Metabolism; Colitis; Diarrhea, Infantile; Enteral Nutrition; Female; Gastrointestinal H | 1991 |
[Changes in cell-mediated immune reactions in Crohn's disease].
Topics: Adult; Colitis; Crohn Disease; Drug Therapy, Combination; Female; Humans; Ileitis; Immunity, Cellula | 1991 |
Collagenous colitis as a cause of chronic diarrhea.
Topics: Aged; Chronic Disease; Colitis; Collagen; Diarrhea; Female; Humans; Prednisone; Sulfasalazine | 1990 |
[Therapy of inflammatory intestinal diseases from the viewpoint of internal medicine].
Topics: Colitis; Combined Modality Therapy; Humans; Parenteral Nutrition; Sulfasalazine | 1990 |
[Collagenous colitis: a disease difficult to define].
Topics: Aged; Colitis; Collagen; Colon; Cortisone; Humans; Male; Sulfasalazine | 1990 |
[Changes in prostaglandin levels in the blood of patients with various forms of chronic colitis before and after treatment].
Topics: Adolescent; Adult; Chronic Disease; Colitis; Dinoprost; Humans; Middle Aged; Prednisolone; Prostagla | 1990 |
Immune complex induced experimental colitis: beneficial effect of sulphasalazine in rabbits.
Topics: Animals; Antibodies; Antibodies, Bacterial; Colitis; Cross Reactions; Escherichia coli; Female; Immu | 1990 |
Experience with topical administration of 4-aminosalicylic acid in ulcerative colitis.
Topics: Administration, Topical; Aminosalicylic Acid; Aminosalicylic Acids; Colitis; Colon; Enema; Humans; I | 1989 |
Does proctosigmoiditis in inflammatory bowel disease presage the imminent onset of symptoms?
Topics: Adolescent; Child; Child, Preschool; Colitis; Crohn Disease; Humans; Inflammatory Bowel Diseases; Me | 1989 |
[Two cases of colitis cystica profunda in dogs].
Topics: Adrenal Cortex Hormones; Animals; Biopsy; Colitis; Colon; Colonoscopy; Dog Diseases; Dogs; Male; Sul | 1989 |
Characterization of spontaneous colitis in cotton-top tamarins (Saguinus oedipus) and its response to sulfasalazine.
Topics: Animals; Aotus trivirgatus; Biopsy; Callithrix; Callitrichinae; Colitis; Double-Blind Method; Drug E | 1985 |
Collagenous colitis: possible response to sulfasalazine and local steroid therapy.
Topics: Administration, Oral; Arthritis, Rheumatoid; Colitis; Collagen; Enema; Female; Humans; Microscopy, E | 1985 |
Cytomegalovirus infection of the colon: a possible role in exacerbations of inflammatory bowel disease.
Topics: Adolescent; Cell Nucleus; Colitis; Cytomegalovirus; Cytomegalovirus Infections; Female; Humans; Incl | 1985 |
Cytomegalovirus infection of the colon: a possible role in exacerbations of inflammatory bowel disease.
Topics: Adolescent; Cell Nucleus; Colitis; Cytomegalovirus; Cytomegalovirus Infections; Female; Humans; Incl | 1985 |
Cytomegalovirus infection of the colon: a possible role in exacerbations of inflammatory bowel disease.
Topics: Adolescent; Cell Nucleus; Colitis; Cytomegalovirus; Cytomegalovirus Infections; Female; Humans; Incl | 1985 |
Cytomegalovirus infection of the colon: a possible role in exacerbations of inflammatory bowel disease.
Topics: Adolescent; Cell Nucleus; Colitis; Cytomegalovirus; Cytomegalovirus Infections; Female; Humans; Incl | 1985 |
Keratoconjunctivitis sicca in the dog associated with the administration of salicylazosulphapyridine (sulphasalazine).
Topics: Animals; Colitis; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Female; Keratoconjunctivitis | 1985 |
Proctocolitis in the dog.
Topics: Animals; Colitis; Dog Diseases; Dogs; Proctocolitis; Sulfasalazine | 1985 |
Kinetics of the spontaneously occurring common variable hypogammaglobulinemia: an analysis of two individuals with previously normal immunoglobulin levels.
Topics: Adult; Agammaglobulinemia; Bone Marrow Cells; Colitis; Humans; Immunization, Passive; Immunoglobulin | 1985 |
A possible mechanism of action of sulfasalazine and 5-aminosalicylic acid in inflammatory bowel diseases: interaction with oxygen free radicals.
Topics: Aminosalicylic Acids; Animals; Chemical Phenomena; Chemistry; Colitis; Free Radicals; Humans; Indome | 1985 |
[Conservative and surgical treatment of Leśniowski-Crohn disease of the colon].
Topics: Adolescent; Colectomy; Colitis; Crohn Disease; Drug Therapy, Combination; Female; Humans; Prednisone | 1985 |
Colitis in Behçet's syndrome.
Topics: Behcet Syndrome; Colitis; Colon; Female; Humans; Middle Aged; Prednisone; Sulfasalazine | 1986 |
Clostridium difficile toxin in chronic idiopathic colitis.
Topics: Adult; Bacterial Proteins; Bacterial Toxins; Chronic Disease; Clostridium; Clostridium Infections; C | 1986 |
Treatment of canine colitis.
Topics: Animals; Colitis; Dog Diseases; Dogs; Sulfasalazine | 1986 |
Keratoconjunctivitis sicca and the treatment of canine colitis.
Topics: Aminosalicylic Acids; Animals; Colitis; Dog Diseases; Dogs; Female; Keratoconjunctivitis; Keratoconj | 1986 |
Collagenous colitis and pulmonary fibrosis. Manifestations of a single disease?
Topics: Aged; Colitis; Collagen Diseases; Diarrhea; Dyspnea; Humans; Intestinal Mucosa; Male; Pulmonary Fibr | 1986 |
[A young woman with Crohn's disease of the esophagus].
Topics: Adult; Barium Sulfate; Colitis; Crohn Disease; Drug Combinations; Esophagitis; Esophagoscopy; Female | 1987 |
Evaluation of oral administration of folic and folinic acid to prevent folate deficiency in patients with inflammatory bowel disease treated with salicylazosulfapyridine.
Topics: Administration, Oral; Adolescent; Adult; Colitis; Female; Folic Acid; Folic Acid Deficiency; Humans; | 1988 |
Olsalazine as an alternative therapy in a patient with sulfasalazine-induced eosinophilic pneumonia.
Topics: Adult; Aminosalicylic Acids; Colitis; Crohn Disease; Humans; Male; Pulmonary Eosinophilia; Sulfasala | 1988 |
Behçet's colitis with oesophageal ulceration treated with sulphasalazine and cyclosporin.
Topics: Behcet Syndrome; Colitis; Cyclosporins; Drug Therapy, Combination; Esophagitis; Female; Humans; Midd | 1988 |
[Collagenous colitis].
Topics: Colitis; Collagen; Colon; Female; Humans; Intestinal Mucosa; Middle Aged; Sulfasalazine | 1988 |
Collagenous colitis: response to treatment.
Topics: Colitis; Collagen; Humans; Prednisone; Sulfasalazine | 1988 |
Colonic complications after renal transplantation.
Topics: Adolescent; Adult; Azathioprine; Cadaver; Colectomy; Colitis; Colon; Diarrhea; Female; Gastrointesti | 1973 |
Pharmacokinetics and azo-link cleavage of salazopyrine in man.
Topics: Aminosalicylic Acids; Colitis; Humans; Ileostomy; Phenobarbital; Sulfasalazine | 1973 |
Lincomycin and clindamycin colitis.
Topics: Administration, Oral; Adrenal Cortex Hormones; Clindamycin; Colitis; Diarrhea; Enema; Humans; Inject | 1974 |
Effects of sulphasalazine (Salazopyrin) on faecal flora in patients with inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aged; Bacteroides; Clostridium; Colitis | 1974 |
[Rectitis (rectosigmoiditis, rare rectocolitis hemorrhagica) in ambulant gastroenterologic metropolitan practice, 37 cases in about 10,000 first admissions].
Topics: Adult; Aged; Colitis; Colon, Sigmoid; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; | 1967 |
[Ulcero-hemorrhagic rectocolotis and Fiessinger-Leroy-Reiter syndrome with inclusion cells].
Topics: Adult; Arthritis, Reactive; Chloramphenicol; Colistin; Colitis; Cytomegalovirus Infections; Humans; | 1968 |
[Hemorrhagic rectocolitis in children].
Topics: Adolescent; Age Factors; Anus Diseases; Betamethasone; Blepharitis; Child; Child, Preschool; Colitis | 1969 |
[First experiences with serial biopsy of the rectal mucosa in inflammatory rectal-colonic diseases].
Topics: Adrenocorticotropic Hormone; Biopsy; Colitis; Colitis, Ulcerative; Colonic Diseases; Humans; Intesti | 1970 |
Clinical and radiologic improvement of regional enteritis and enterocolitis after treatment with salicylazosulfapyridine.
Topics: Adolescent; Adult; Aged; Cecum; Colitis; Colon; Crohn Disease; Female; Humans; Ileum; Male; Radiogra | 1971 |
The management of ulcerative colitis and granulomatous colitis.
Topics: Adrenocorticotropic Hormone; Adult; Anti-Infective Agents; Antineoplastic Agents; Colitis; Colitis, | 1971 |
[Our experiences in the use of steroid hormones and salazopyrin in hemorrhagic rectocolitis].
Topics: Adult; Aged; Chronic Disease; Colitis; Dexamethasone; Female; Gastrointestinal Hemorrhage; Glucocort | 1970 |
[Therapy of radiogenic colitis with salicylazosulfapyridine (azulfidine)].
Topics: Cobalt Isotopes; Colitis; Diarrhea; Female; Humans; Radiation Injuries; Radioisotope Teletherapy; Su | 1972 |