sulfasalazine has been researched along with Colitis, Granulomatous in 598 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Excerpt | Relevance | Reference |
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"To determine whether sulphasalazine plus prednisone is more effective than sulphasalazine alone in treating active Crohn disease." | 9.07 | Sulphasalazine and prednisone compared with sulphasalazine for treating active Crohn disease. A double-blind, randomized, multicenter trial. ( Rijk, MC; van Hogezand, RA; van Lier, HJ; van Tongeren, JH, 1991) |
"In an open study, sulfasalazine was given to 15 HLA-B27 positive patients with asymmetrical pauciarticular arthritis and enthesopathies resistant to nonsteroidal antiinflammatory drugs (NSAID)." | 9.05 | HLA-B27 related arthritis and bowel inflammation. Part 1. Sulfasalazine (salazopyrin) in HLA-B27 related reactive arthritis. ( Mielants, H; Veys, EM, 1985) |
"A severe systemic reaction to sulfasalazine developed in a 21-year old female with rheumatoid arthritis characterized by eosinophilia, granulomatous enteritis and myelotoxicity, cholestatic hepatitis, and seizures." | 7.71 | Is it Crohn's disease? A severe systemic granulomatous reaction to sulfasalazine in patient with rheumatoid arthritis. ( Fontana, RJ; Greenson, J; Haftel, HM; Quallich, LG, 2001) |
"To determine the safety of corticosteroids and sulfasalazine in pregnancy associated with inflammatory bowel disease, we reviewed the outcome of 531 such pregnancies in a national survey." | 7.66 | Pregnancy in inflammatory bowel disease: effect of sulfasalazine and corticosteroids on fetal outcome. ( Ahmed, SW; Dobbins, WO; Korelitz, BI; Mogadam, M, 1981) |
"Sulfasalazine is an anti-inflammatory agent commonly used in the treatment of autoimmune conditions such as inflammatory bowel disease and rheumatoid arthritis." | 5.46 | Sulfasalazine-Induced Crystalluria Causing Severe Acute Kidney Injury. ( Durando, M; Kim, JS; Tiu, H, 2017) |
"Development of hepatic encephalopathy led to urgent liver transplantation in both cases." | 5.30 | [Fulminant hepatitis in two children treated with sulfasalazine for Crohn disease]. ( Besnard, M; Cézard, JP; Chardot, C; Debray, D; Durand, P; Fabre, M, 1999) |
"6-Mercaptopurine is an effective and useful drug in the treatment of fistulae, as it is in other manifestations of chronic unrelenting Crohn's disease." | 5.27 | Favorable effect of 6-mercaptopurine on fistulae of Crohn's disease. ( Korelitz, BI; Present, DH, 1985) |
"Twenty-four patients with spondylitis and Crohn's disease or ulcerative colitis, treated with 5-ASA or sulfasalazine, were randomised and assessed by an investigator independent from the spa staff: 12 were submitted to a cycle of mud-bath treatment (12 mud packs and 12 thermal baths over a period of two weeks) and 12 were enrolled as controls." | 5.12 | Mud-bath treatment in spondylitis associated with inflammatory bowel disease--a pilot randomised clinical trial. ( Cardinale, G; Cozzi, F; Dani, L; Oliviero, F; Podswiadek, M; Punzi, L; Sfriso, P, 2007) |
"To determine whether sulphasalazine plus prednisone is more effective than sulphasalazine alone in treating active Crohn disease." | 5.07 | Sulphasalazine and prednisone compared with sulphasalazine for treating active Crohn disease. A double-blind, randomized, multicenter trial. ( Rijk, MC; van Hogezand, RA; van Lier, HJ; van Tongeren, JH, 1991) |
"In an open study, sulfasalazine was given to 15 HLA-B27 positive patients with asymmetrical pauciarticular arthritis and enthesopathies resistant to nonsteroidal antiinflammatory drugs (NSAID)." | 5.05 | HLA-B27 related arthritis and bowel inflammation. Part 1. Sulfasalazine (salazopyrin) in HLA-B27 related reactive arthritis. ( Mielants, H; Veys, EM, 1985) |
"We report large-volume secretory diarrhea and intestinal pseudo-obstruction in a man whom ultimately proved to have Crohn's disease that responded to sulfasalazine and steroids with resolution of all his symptoms." | 4.79 | Massive secretory diarrhea and pseudo-obstruction as the initial presentation of Crohn's disease. ( Carethers, JM; McDonnell, WM; Owyang, C; Scheiman, JM, 1996) |
" Tofacitinib is a Janus kinase inhibitor approved for treating rheumatoid arthritis and ulcerative colitis." | 4.31 | Tofacitinib for the treatment of inflammatory bowel disease-associated arthritis: two case reports. ( Haq, SA; Momen Majumder, MS; Rasker, JJ, 2023) |
"Sulfasalazine and FTY720 treatment did not prevent body weight loss or reduce clinical scores of diarrhea or intestinal gross pathology, when compared with vehicle treatment." | 3.77 | Pharmacologic evaluation of sulfasalazine, FTY720, and anti-IL-12/23p40 in a TNBS-induced Crohn's disease model. ( Benson, EL; Heuvelman, DM; Masferrer, JL; Radi, ZA, 2011) |
" When given in a dosage of 2g daily it will prevent relapses in quiescent colitis." | 3.76 | Sulphasalazine: a review of 40 years' experience. ( Watkinson, G, 1986) |
"In the acute treatment of Crohn's disease, Pentasa and Salofalk seem to be more effective than placebo." | 3.76 | Oral 5-aminosalicylic acid preparations in treatment of inflammatory bowel disease. An update. ( Martin, F, 1987) |
"The drug is useful in the treatment of active ulcerative colitis as well as in preventing relapses of the disease in remission." | 3.75 | Sulfasalazine. Pharmacology, clinical use, toxicity, and related new drug development. ( Peppercorn, MA, 1984) |
"A severe systemic reaction to sulfasalazine developed in a 21-year old female with rheumatoid arthritis characterized by eosinophilia, granulomatous enteritis and myelotoxicity, cholestatic hepatitis, and seizures." | 3.71 | Is it Crohn's disease? A severe systemic granulomatous reaction to sulfasalazine in patient with rheumatoid arthritis. ( Fontana, RJ; Greenson, J; Haftel, HM; Quallich, LG, 2001) |
" Low birth weight were observed after the medication of prednisolone and a manifestation of the ulcerous colitis during the gravidity." | 3.68 | [Pregnancy and chronic inflammatory bowel diseases]. ( Hänert, E; Schneider, W, 1991) |
" We compare the natural course of amyloidosis complicating Crohn's disease with these complicating familial Mediterranean fever (FMF), and discuss the role of resection and the rationale behind colchicine therapy." | 3.67 | Crohn's ileitis complicated by amyloidosis: observations and therapeutic considerations. ( Bass, D; Becker, SA; Nissim, F, 1985) |
"Despite the extensive use of sulfasalazine (SAS) and/or 5-aminosalicylic acid (5-ASA) in patients with inflammatory bowel disease and, more recently, rheumatoid arthritis, their mode of action has not been elucidated so far." | 3.67 | Possible mode of action of 5-aminosalicylic acid. ( Dreyling, KW; Goebell, H; May, B; Peskar, BM; Schaarschmidt, K, 1987) |
"A man with Crohn's colitis developed eosinophilic pneumonia after treatment with sulfasalazine." | 3.67 | Olsalazine as an alternative therapy in a patient with sulfasalazine-induced eosinophilic pneumonia. ( Nadorp, JH; Scherpenisse, J; van den Bosch, JM; van der Valk, PD; van Hees, PA, 1988) |
"To determine the safety of corticosteroids and sulfasalazine in pregnancy associated with inflammatory bowel disease, we reviewed the outcome of 531 such pregnancies in a national survey." | 3.66 | Pregnancy in inflammatory bowel disease: effect of sulfasalazine and corticosteroids on fetal outcome. ( Ahmed, SW; Dobbins, WO; Korelitz, BI; Mogadam, M, 1981) |
"Partial Enteral Nutrition and Crohn's Disease Exclusion Diets may be appropriate for inducing remission in some adult patients, with trials ongoing." | 3.01 | Mild Crohn's Disease: Definition and Management. ( Agrawal, M; Ananthakrishnan, AN; Claytor, J; Colombel, JF; Kumar, P; Ungaro, RC, 2023) |
"pylori." | 2.69 | Assessment of the prevalence of infection with Helicobacter pylori in patients with inflammatory bowel disease. ( Duncan, HD; Green, JR; Pearce, CB; Timmis, L, 2000) |
"Management of perianal Crohn's disease is still controversial, and reports on large series are very few in the literature." | 2.68 | Management of perianal Crohn's disease. Results of a multicenter study in Italy. ( Arcanà, F; Basso, L; Buffatti, P; Di Bella, F; Doldi, A; Forcheri, V; Gaetini, R; Interisano, A; Pera, A; Pescatori, M, 1995) |
"Twenty nine children with Crohn's disease were studied before and after treatment with steroids or an elemental diet to assess the effect of disease activity and treatment on serum insulin like growth factor I (IGF-I), insulin like growth factor binding protein (IGFBP-1), and insulin concentrations." | 2.67 | Insulin like growth factor-I, insulin like growth factor binding protein-1, and insulin in childhood Crohn's disease. ( Holly, JM; Miller, V; Taylor, F; Thomas, AG, 1993) |
"Patients with active Crohn's disease (Crohn's Disease Activity Index greater than 200) were randomized to receive either enteral nutrition with a liquid oligopeptide diet (n = 55) or a combination of 6-methylprednisolone, 48 mg daily, subsequently tapered, and sulfasalazine, 3 g daily (n = 52)." | 2.67 | Comparison of enteral nutrition and drug treatment in active Crohn's disease. Results of the European Cooperative Crohn's Disease Study. IV. ( Bauer, P; Fleig, WE; Klaus-Wentz, B; Lochs, H; Malchow, H; Schirrmeister, J; Sommer, H; Steinhardt, HJ; Vogelsang, H; Zeitz, M, 1991) |
"It is concluded that postoperative recurrence is best prevented by resecting nonradically and prescribing 3 g of sulfasalazine daily at least over 2 years." | 2.66 | Postoperative recurrence of Crohn's disease in relation to radicality of operation and sulfasalazine prophylaxis: a multicenter trial. ( Ewe, K; Herfarth, C; Jesdinsky, HJ; Malchow, H, 1989) |
"The course of 205 patients with Crohn's disease at one gastroenterological center was studied in patients with conservative drug treatment or with operative management of their disease." | 2.66 | Clinical relapse of Crohn's disease under standardized conservative treatment and after excisional surgery. ( Dirks, E; Eigler, FW; Förster, S; Goebell, H; Quebe-Fehling, E; Schaarschmidt, K, 1989) |
"Clinical improvement in Crohn's disease was seen in 87% of patients of the 5-aminosalicylic acid group and in 80% of the salazosulfapyridine group." | 2.66 | [Successful acute treatment of chronic inflammatory intestinal diseases with oral 5-aminosalicylic acid]. ( Bode, JC; Frühmorgen, P; Heller, T; Klotz, U; Maier, K; von Gaisberg, U, 1985) |
"130 patients with Crohn's disease were colonoscopied in a multicenter trial." | 2.66 | European Cooperative Crohn's Disease Study (ECCDS): colonoscopy. ( Brandes, JW; Lorenz-Meyer, H; Malchow, H; Miller, B; Stock, H, 1985) |
"In the European Cooperative Crohn's Disease Study patients from 14 centers were included in whom diagnosis was made within 2 years before study entry on the basis of generally accepted radiological, endoscopical and/or histological criteria or a combination of all." | 2.66 | European Cooperative Crohn's Disease Study (ECCDS): clinical features and natural history. ( Holtermüller, KH; Kasper, H; Loeschke, K; Schäfer, H; Steinhardt, HJ, 1985) |
"26 in-patients (17 with Crohn's disease, 9 with ulcerative colitis) were given high-molecular (diet 1; 12 patients) or low-molecular (diet 2; 14 patients) elemental diets (6." | 2.66 | [Adjuvant therapy with elemental diet in chronic inflammatory intestinal diseases. Comparative study]. ( Heskamp, R; Rabast, U, 1986) |
" Metronidazole and azathioprin are considered to be reserve drugs and can be used in the treatment of fistulae or in order to cut down the dosage of prednisolone during remission." | 2.66 | [Drug therapy of chronic inflammatory intestinal diseases--current status of 5-aminosalicylic acid]. ( Gerok, W; Schölmerich, J, 1986) |
" The drug was more effective than placebo in closing fistulas (31 vs 6%) and in permitting discontinuation or reduction of steroid dosage (75 vs." | 2.65 | Treatment of Crohn's disease with 6-mercaptopurine. A long-term, randomized, double-blind study. ( Glass, JL; Korelitz, BI; Pasternack, BS; Present, DH; Sachar, DB; Wisch, N, 1980) |
"The response of active Crohn's disease to sulphasalazine (4-6 g per day) has been studied in a placebo-controlled trial." | 2.65 | Effect of sulphasalazine in patients with active Crohn's disease: a controlled double-blind study. ( Bakker, JH; Driessen, M; Ten Velde, GP; Van Elteren, PH; Van Hees, PA; Van Hogezand, RA; Van Lier, HJ; Van Tongeren, JH, 1981) |
"A significant decrease of the Crohn's disease activity index and a significantly lower hospitalization time suggest a benefit in using the lavage method." | 2.65 | Intestinal lavage in the treatment of Crohn's disease: a pilot study. ( Schmidt, FW; Wellmann, W, 1982) |
"Seventy-eight patients with active Crohn's disease participated in a randomized, double-blind, cross-over trial." | 2.65 | A comparative study of metronidazole and sulfasalazine for active Crohn's disease: the cooperative Crohn's disease study in Sweden. II. Result. ( Alm, T; Bárány, F; Bergelin, I; Ganrot-Norlin, K; Hoevels, J; Huitfeldt, B; Järnerot, G; Krause, U; Krook, A; Lindström, B; Nordle, O; Rosén, A; Ursing, B, 1982) |
"Cefoxitin was used in 55 cases and doxycycline in 47." | 2.65 | Short-term systemic prophylaxis with cefoxitin and doxycycline in colorectal surgery. A prospective, randomized study. ( Darle, N; Ivarsson, L; Kewenter, JG; Norrby, R; Seeberg, S, 1982) |
"26 children with acute symptoms of Crohn's disease were treated with steroids and sulfasalazine (group A, 9 patients), with an elementary diet and sulfasalazine (group B, 10 patients), or with an elementary diet together with steroids and sulfasalazine (group C, 7 patients)." | 2.65 | [Basic diet in Crohn's disease]. ( Nützenadel, W; Stober, B; Ullrich, F, 1983) |
" Plasma and urine concentrations of 5-AS and its acetylated major metabolite (AcAS) were monitored during one dosing interval." | 2.65 | Disposition of 5-aminosalicylic acid, the active metabolite of sulphasalazine, in man. ( Fischer, C; Klotz, U; Maier, K; Stumpf, E; von Gaisberg, U, 1983) |
"Sulfasalazine alone was least effective in overall comparison of all patients (p less than 0." | 2.65 | European Cooperative Crohn's Disease Study (ECCDS): results of drug treatment. ( Brandes, JW; Ehms, H; Ewe, K; Goebell, H; Jesdinsky, H; Malchow, H; Sommer, H, 1984) |
"A standard clinical grading system, the Crohn's Disease Activity Index (CDAI) was developed to allow uniform decentralized clinical evaluation and decision-making throughout the 5 yr of the study." | 2.65 | National Cooperative Crohn's Disease Study: study design and conduct of the study. ( Becktel, JM; Best, WR; Kern, F; Lenk, LF; Singleton, JW; Summers, RW; Winship, DH, 1979) |
"The response of active and quiescent Crohn's disease to prednisone, sulfasalazine, or azathioprine has been studied in 569 patients in a placebo-controlled, randomized, multicenter cooperative trial." | 2.65 | National Cooperative Crohn's Disease Study: results of drug treatment. ( Becktel, JM; Best, WR; Kern, F; Sessions, JT; Singleton, JW; Summers, RW; Switz, DM, 1979) |
"Azathioprine was approximately as toxic as prednisone but no more effective than placebo in suppressing active disease." | 2.65 | National Cooperative Crohn's Disease Study: adverse reactions to study drugs. ( Kelley, ML; Law, DH; Mekhjian, HS; Singleton, JW; Sturdevant, RA, 1979) |
"This might mean that patients with Crohn's disease undergoing an early operation have a better chance of escaping recurrences." | 2.64 | Postoperative treatment with corticosteroids and salazosulphapyridine (Salazopyrin) after radical resection for Crohn's disease. ( Bergman, L; Krause, U, 1976) |
"Sulfasalazine was not significantly superior to any therapy including placebo." | 2.55 | Comparative Effectiveness of Mesalamine, Sulfasalazine, Corticosteroids, and Budesonide for the Induction of Remission in Crohn's Disease: A Bayesian Network Meta-analysis. ( Clement, F; Coward, S; Ghosh, S; Hazlewood, G; Holmes, R; Kaplan, GG; Kuenzig, ME; McBrien, K; Panaccione, R; Rezaie, A; Seow, CH, 2017) |
"Sulfasalazine was significantly less effective than corticosteroids and inferior to combination therapy with corticosteroids (RR 0." | 2.53 | Aminosalicylates for induction of remission or response in Crohn's disease. ( Hanauer, S; Lim, WC; MacDonald, JK; Wang, Y, 2016) |
"Azathioprine was significantly inferior to infliximab for induction of steroid-free clinical remission." | 2.53 | Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease. ( Chande, N; MacDonald, JK; Parker, CE; Townsend, CM, 2016) |
"We report on an 11-year-old girl with juvenile idiopathic arthritis, who developed Crohn's disease (CD) while taking etanercept for her arthritis." | 2.46 | Crohn's disease during etanercept therapy in juvenile idiopathic arthritis: a case report and review of the literature. ( Dick, A; Girschick, HJ; Morbach, H; Wiegering, V, 2010) |
"Crohn's disease and ulcerative colitis, together popularly known as inflammatory bowel disease (IBD), are characterized by a number of extraintestinal manifestations." | 2.46 | Pancreatitis in inflammatory bowel diseases. ( Das, K; Pitchumoni, CS; Rubin, A, 2010) |
"Due to the frequency of preceding pulmonary disease and the common temporal dissociation regarding intestinal disease, pulmonary manifestations of inflammatory bowel disease are at high risk of being overlooked." | 2.46 | [Pulmonary manifestations of inflammatory bowel disease]. ( Bachmann, O; Länger, F; Rademacher, J, 2010) |
"Sulfasalazine was more likely to induce remission (RR 1." | 2.46 | Aminosalicylates for induction of remission or response in Crohn's disease. ( Hanauer, S; Lim, WC, 2010) |
"ulcerative colitis and Crohn's disease), for both active disease and the control of remission." | 2.44 | Drug insight: aminosalicylates for the treatment of IBD. ( Munck, LK; Nielsen, OH, 2007) |
"Although the treatment of Crohn's disease has improved significantly during past decade, the treatment of intestinal BD is still problematic." | 2.44 | [Pathogenesis and treatment of intestinal Behçet's disease]. ( Kim, HJ; Lee, CK, 2007) |
" Corticosteroids, the mainstay of treatment of acute exacerbations are not effective in the maintenance of remission and its chronic use is limited by numerous adverse events." | 2.43 | Oral 5-aminosalicylic acid for maintenance of medically-induced remission in Crohn's Disease. ( Akobeng, AK; Gardener, E, 2005) |
"Ulcerative colitis (UC) and Crohn's disease (CD), collectively known as inflammatory bowel disease (IBD), afflict an estimated one million Americans and produce symptoms that impair quality of life and ability to function." | 2.42 | The state of the art in the management of inflammatory bowel disease. ( Hanauer, SB; Present, DH, 2003) |
"The aetiology of Crohn's disease still remains obscure, therefore medical therapy is directed towards symptomatic relief in active disease and relapse prevention in the long-term setting." | 2.42 | Review article: medical treatment of mild to moderately active Crohn's disease. ( Löfberg, R, 2003) |
"The aetiology of Crohn's disease is unknown and therefore no curative treatments are available for the disease." | 2.42 | Review article: maintenance treatment of Crohn's disease. ( Biancone, L; De Nigris, F; Fantini, M; Fina, D; Geremia, A; Pallone, F; Tosti, C, 2003) |
"Mesalamine has no clear benefit over placebo in treating active Crohn's disease." | 2.42 | Review article: mild to moderate Crohn's disease--defining the basis for a new treatment algorithm. ( Feagan, BG; Sandborn, WJ, 2003) |
"It describes the treatment of ulcerative colitis according to the different groups of patients and the degree of activity." | 2.41 | [Conservative therapy of inflammatory bowel diseases]. ( Nagy, F, 2002) |
" Metronidazole and 6-mercaptopurine or azathioprine also seem to be of benefit in postoperative prophylaxis of disease recurrence, but additional controlled studies are required to define better the efficacy and dose-response of these agents." | 2.41 | Medical therapy to reduce postoperative Crohn's disease recurrence. ( Achkar, JP; Hanauer, SB, 2000) |
" Oral controlled-release budesonide has demonstrated comparable efficacy to prednisolone with less risk for adverse effects, although many questions remain regarding the long-term use of this agent." | 2.41 | Conventional treatment of Crohn's disease: objectives and outcomes. ( Rutgeerts, PJ, 2001) |
"The role of salicylates in Crohn's disease is limited to the mild activity phase; further data are required to clarify its role in maintenance on remission." | 2.41 | New steroids and new salicylates in inflammatory bowel disease: a critical appraisal. ( Campieri, M, 2002) |
"Extra-intestinal manifestations of Crohn's disease are well described." | 2.39 | [Crohn's disease with isolated vulvar localization and pregnancy. A case report]. ( Ben Osmane, A; Bitri, M; Chelly, H; Haouet, S, 1994) |
"Epidermolysis bullosa acquisita is a rare autoimmune subepidermal bullous disease that affects both the skin and mucosae and is frequently associated with Crohn's disease." | 2.39 | Localized epidermolysis bullosa acquisita of the esophagus in a patient with Crohn's disease. ( Bertheau, P; Cadot, M; Caux, F; Grateau, C; Guigui, B; Heller, M; Lémann, M; Prost, C; Schattenkirchner, S, 1996) |
"The choice of medical therapies for Crohn's disease continues to grow." | 2.39 | Review article: the medical management of Crohn's disease. ( Elton, E; Hanauer, SB, 1996) |
" Pericarditis as a side effect induced by sulfasalazine or 5-aminosalicylic acid, drugs used in the therapy of these diseases, was first described only 7 years ago." | 2.39 | [Pericarditis in chronic inflammatory bowel disease: underlying disease or side effects of therapy? Clinical problem solving]. ( Krähenbühl, S; Kupferschmidt, H; Langenegger, T, 1996) |
"Crohn's disease is a chronic relapsing inflammatory disorder primarily affecting the gastrointestinal system." | 2.39 | [Myositis--a rare complication of Crohn disease]. ( Druschky, A; Engelhardt, A; Heckmann, J, 1996) |
"Crohn's disease is a chronic inflammatory intestinal disorder characterized in most patients by repeated episodes of diminished and exacerbated symptoms." | 2.38 | Maintenance of symptomatic remission in patients with Crohn's disease. ( Stark, ME; Tremaine, WJ, 1993) |
"In severely active Crohn's disease, systemic corticosteroids have to be administered." | 2.38 | [Local or systemic treatment of inflammatory bowel diseases?]. ( Halter, F; Schmassmann, A, 1993) |
"The standard therapy of ulcerative colitis and Crohn's disease is based on the treatment with corticosteroids, sulfasalazine and 5-aminosalicylic acid (mesalazine)." | 2.38 | [Drug therapy of chronic inflammatory bowel disease--reliable standards and new developments]. ( Fischbach, W, 1992) |
"Crohn's disease is a perplexing panintestinal disease whose etiology is unknown." | 2.38 | Crohn's disease of the small bowel. ( Fazio, VW; Hyman, NH, 1991) |
"Ulcerative colitis and Crohn's disease are chronic inflammatory bowel diseases." | 2.38 | Involvement of oxygen-derived free radicals in the pathogenesis of chronic inflammatory bowel disease. ( Ahnfelt-Rønne, I; Nielsen, OH, 1991) |
"The association between cutaneous polyarteritis nodosa and Crohn's disease is discussed and the treatment of earlier reported cases is reviewed." | 2.38 | Cutaneous polyarteritis nodosa associated with Crohn's disease. Report and review of the literature. ( Gudbjörnsson, B; Hällgren, R, 1990) |
"Sulfasalazine continues to be a common treatment for active Crohn's disease." | 2.38 | The role of mesalazine in Crohn's disease. ( Hanauer, SB, 1990) |
"For patients with more extensive ulcerative colitis with moderate symptoms, prednisone and/or sulfasalazine will result in improvement in about 80% of patients." | 2.37 | Current status of drug therapy for inflammatory bowel disease. ( Peppercorn, MA, 1985) |
"The reported incidence of Crohn's disease has increased in the last 30 years." | 2.37 | Chronic inflammatory bowel disease. ( Sanderson, IR, 1986) |
"Ulcerative colitis and Crohn's disease are chronic intestinal disorders with diverse presentations that must be familiar to pediatricians." | 2.37 | Inflammatory bowel disease in children. ( Kirschner, BS, 1988) |
"Ulcerative colitis is not associated with a higher spontaneous abortion rate than the general population, although it is not clear whether certain subgroups of patients have a higher rate of abortion." | 2.36 | Inflammatory bowel disease and pregnancy. ( Spiro, HM; Vender, RJ, 1982) |
"Crohn's disease is a perplexing disease with a high rate of morbidity and complications." | 2.35 | The protean manifestations of Crohn's disease. ( Farmer, RG, 1975) |
"It is important to distinguish between ulcerative colitis and Crohn's colitis because response to treatment and prognosis are different." | 2.35 | Inflammatory disease of the colon: ulcerative colitis and Crohn's colitis. ( Ament, ME, 1975) |
"The majority of patients had Crohn's disease (CD) (60%) and most of them were in clinical remission." | 1.62 | COVID-19 in IBD: The experience of a single tertiary IBD center. ( Belluzzi, A; Calabrese, C; Calandrini, L; Decorato, A; Dussias, N; Filippone, E; Gionchetti, P; Laureti, S; Melotti, L; Peruzzi, G; Poggioli, G; Privitera, H; Rizzello, F; Rottoli, M; Salice, M; Scaioli, E; Siniscalchi, A, 2021) |
"The proportion of women with Crohn's disease and ulcerative colitis on any treatment during pregnancy was 56." | 1.62 | The Patterns of Use of Medications for Inflammatory Bowel Disease During Pregnancy in the US and Sweden Are Changing. ( Bateman, BT; Brill, G; Bröms, G; Desai, RJ; Friedman, S; Hernandez-Diaz, S; Huybrechts, KF; Kim, SC; Wood, ME, 2021) |
"Sulfasalazine is an anti-inflammatory agent commonly used in the treatment of autoimmune conditions such as inflammatory bowel disease and rheumatoid arthritis." | 1.46 | Sulfasalazine-Induced Crystalluria Causing Severe Acute Kidney Injury. ( Durando, M; Kim, JS; Tiu, H, 2017) |
"Prednisone use was associated with higher mortality [HR = 3." | 1.46 | Five-year Safety Data From ENCORE, a European Observational Safety Registry for Adults With Crohn's Disease Treated With Infliximab [Remicade®] or Conventional Therapy. ( Boice, J; Colombel, JF; Cornillie, F; D'Haens, G; Ghosh, S; Hommes, DW; Huang, Z; Huyck, S; Lindgren, S; Panes, J; Prantera, C; Reinisch, W, 2017) |
"Treatment with sulfasalazine, low dose of natrexone or their combination resulted in significant improvement of all measured parameters compared with enteritis group." | 1.43 | Evaluation of therapeutic effect of low dose naltrexone in experimentally-induced Crohn's disease in rats. ( Abdel-Salam, LO; Kamel, MM; Khattab, A; Osman, AS; Tawfik, DI; Tolba, HM, 2016) |
"Dacryoadenitis is the rarest form of ocular adnexal involvement in regional enteritis, which affects the orbit far more frequently than ulcerative colitis." | 1.40 | Granulomatous dacryoadenitis in regional enteritis (crohn disease). ( Jakobiec, FA; Kazim, M; Lane, KA; Rashid, A, 2014) |
"Metastatic Crohn's disease is a rare inflammatory process that is non-contiguous from the bowel." | 1.38 | Metastatic Crohn's disease of the penis: two cases. ( Husain, E; Hussain, F; McClinton, S; Ormerod, A; Vint, R, 2012) |
"Medical therapy for Crohn's disease (CD) has changed significantly over the past 20 years with increasing use of immunosuppressives." | 1.38 | Has there been a change in the natural history of Crohn's disease? Surgical rates and medical management in a population-based inception cohort from Western Hungary between 1977-2009. ( Balogh, M; David, G; Erdelyi, Z; Golovics, PA; Horvath, A; Kiss, LS; Komaromi, E; Lakatos, L; Lakatos, PL; Lovasz, BD; Mester, G; Molnar, C; Pandur, T; Szathmari, M; Szipocs, I; Veres, G, 2012) |
"The birth outcomes in women with ulcerative colitis are examined in a nationwide, Danish, cohort of women based on data from the Danish National Hospital Discharge Registry and the Danish Medical Birth Registry, and within a Hungarian case-control data set." | 1.37 | Birth outcome in women with ulcerative colitis and Crohn's disease, and pharmacoepidemiological aspects of anti-inflammatory drug therapy. ( Nørgård, BM, 2011) |
"paratuberculosis; isolates from Crohn's disease patients tended to be more susceptible than were bovine-origin isolates." | 1.35 | Thiopurine drugs azathioprine and 6-mercaptopurine inhibit Mycobacterium paratuberculosis growth in vitro. ( Collins, MT; Shin, SJ, 2008) |
"Crohn's disease is a chronic idiopathic slowly developing transmural inflammation of the digestive system." | 1.34 | Sinonasal involvement as a rare extraintestinal manifestation of Crohn's disease. ( Bertrand, B; Daele, J; Dartevelle, M; Eloy, P; Fridman, V; Goffart, Y; Leruth, E; Melange, M; Nollevaux, MC, 2007) |
"The neurological manifestations of Crohn's disease are rare, dominated by multiple mononeuropathies and the abnormalities of the white matter." | 1.34 | [Crohn's disease presenting with recurrent acute polyradiculoneuropathy]. ( El Moutawakil, B; Gam, I; Rafai, MA; Rhimou, A; Slassi, I; Tahiri, JM, 2007) |
"Mesalamine has a well-established role in the management of ulcerative colitis." | 1.33 | The case for using 5-aminosalicyclates in Crohn's disease: pro. ( Hanauer, SB, 2005) |
"The association of Crohn's disease and ankylosing spondylitis is described in up to 30% of cases." | 1.33 | Treatment with infliximab in a patient with ankylosing spondylitis and Crohn's disease. ( Chira, R; Marinescu, C; Rednic, N; Rednic, S; Rogojan, L, 2006) |
"We report a rare case of drug-induced pneumonitis, probably caused by salazosulfapyridine, showing a radiographic pattern of multiple pulmonary nodules and lymphadenopathy." | 1.33 | [A case of salazosulfapyridine-induced pneumonitis presenting with multiple pulmonary nodules and lymphadenopathy]. ( Kasai, S; Nishine, H; Nishiyama, H; Tokuda, H; Yoshikawa, M, 2006) |
"Azathioprine has demonstrable benefits after induction therapy with prednisone." | 1.32 | Clinical features and management of Crohn's disease in Chinese patients. ( Chu, XQ; Jia, LM; Shi, XH; Wang, FM; Zheng, JJ, 2004) |
"The risk of colorectal cancer was not increased, either in the total group of patients or in patients with colonic Crohn's disease exclusively (standardized morbidity ratio, 1." | 1.32 | Intestinal and extra-intestinal cancer in Crohn's disease: follow-up of a population-based cohort in Copenhagen County, Denmark. ( Binder, V; Jess, T; Langholz, E; Munkholm, P; Winther, KV, 2004) |
"In patients with Crohn's disease on long term azathioprine therapy, it is clear that myelosuppression, particularly leucopenia, is caused by other factors in addition to variable TPMT activity and therefore monitoring of blood cell counts throughout treatment is essential." | 1.31 | TPMT in the treatment of Crohn's disease with azathioprine. ( Lennard, L, 2002) |
"Retinal neovascularization was detected during the follow-up." | 1.31 | Unilateral retinal vasculitis, branch retinal artery occlusion and subsequent retinal neovascularization in Crohn's disease. ( Durak, I; Ergin, MH; Koçak, N; Saatci, OA, 2001) |
"We describe a patient with IgA nephropathy associated with Crohn disease." | 1.31 | An adolescent with IgA nephropathy and Crohn disease: pathogenetic implications. ( Kuwajima, H; Okada, M; Takemura, T; Yagi, K; Yanagida, H, 2002) |
" The long-term use of immunodulating agents in patients with CD is not without risks, and early therapy related myelodysplasia might not be easily detected by blood count and morphology assessment alone." | 1.31 | Clonal marrow abnormalities after azathioprine and sulfasalazine exposure in Crohn's disease: a cautionary tale. ( Au, WY; Lai, KC; Ma, SK; Wan, TS; Yuen, MF, 2002) |
"The concept of the Crohn's disease as a non-children illness underwent a change with the widening of diagnostic possibilities, wide use of the endoscopic method of diagnostics in pediatric practice, and histological studies of biopsy materials." | 1.31 | [Crohn's disease in children]. ( Rumiantsev, VG; Shchigoleva, NE, 2002) |
"Few cases associating Crohn's disease and celiac disease have been reported." | 1.31 | [Association of asymptomatic celiac disease and Crohn's disease]. ( Ben Yaghlene, L; Boubaker, J; Filali, A; Hamzaoui, S; Karoui, S, 2000) |
"Pancreatitis was significantly more frequent in girls as compared to boys (P = 0." | 1.31 | [Pancreatic involvement in inflammatory bowel diseases in children]. ( Cézard, JP; Faure, C; Hugot, JP; Le Large-Guiheneuf, C; Mougenot, JF; Munck, A; Navarro, J, 2002) |
"An 11-year-old girl with Crohn's disease was given 40 mg/kd/day of sulphasalazine after achieving remission with prednisone." | 1.30 | [Hypersensitivity to 5-aminosalicylic acid. Value of desensitization by oral route]. ( Aboufadel, A; Hermier, M; Lachaux, A; Le Gall, C; Loras-Duclaux, I, 1997) |
"Current available therapies for Crohn's disease in Japan are reviewed in this report." | 1.30 | [Current medical therapies for Crohn's disease in Japan]. ( Haga, Y; Munakata, A, 1997) |
"Vulvar involvement in Crohn's disease is uncommon." | 1.30 | [Vulvar Crohn disease: 3 cases]. ( Ben Osman, A; Fenniche, S; Haouet, S; Mokni, M, 1997) |
"1." | 1.30 | [Inflammatory bowel disease and pregnancy: clinical study of mutual influence, clinical course and treatment]. ( Hiwatashi, N; Katsurashima, Y; Kinouchi, Y; Noguchi, M; Oriuchi, T; Toyota, T, 1999) |
"Development of hepatic encephalopathy led to urgent liver transplantation in both cases." | 1.30 | [Fulminant hepatitis in two children treated with sulfasalazine for Crohn disease]. ( Besnard, M; Cézard, JP; Chardot, C; Debray, D; Durand, P; Fabre, M, 1999) |
"We described a 37-year-old man with Crohn's disease (CD) resembling systemic lupus erythematosus (SLE) at his disease onset." | 1.30 | [Crohn's disease with the onset resembling systemic lupus erythematosus]. ( Baba, M; Hiranuma, M; Horie, T; Kitamura, N; Nishinarita, S; Shimizu, T; Son, K; Tomita, Y, 1999) |
"Our results show that, in Crohn's disease patients, the expression of E-selectin was up-regulated 5." | 1.29 | Up-regulation of E-selectin and intercellular adhesion molecule-1 differs between Crohn's disease and ulcerative colitis. ( Ghosh, L; Pooley, N; Sharon, P, 1995) |
" Adverse events occurred in 64% of all patients (highest 85% in AS and lowest 50% in ulcerative colitis, CU)." | 1.29 | Side effects of sulphasalazine in patients with rheumatic diseases or inflammatory bowel disease. ( Laasila, K; Leirisalo-Repo, M, 1994) |
"In Crohn's disease as well as in ulcerative colitis steroids are of major importance in the treatment of active disease." | 1.29 | [Current therapeutic possibilities in chronic inflammatory intestinal diseases]. ( Schölmerich, J, 1995) |
"In summary: the Crohn's disease cannot be cured by surgical means." | 1.29 | [The role of conservative surgery in Crohn disease: practical results obtained from a case]. ( Csonka, C; Ludmány, E; Nagy, L, 1993) |
"Crohn's recurrence is the appearance of objective signs--defined radiologically, endoscopically or pathologically--of Crohn's disease in the bowel of a patient who has previously had a resection of all macroscopically diseased tissue." | 1.29 | Recurrence of Crohn's disease in the neoterminal ileum after ileal resection: is prevention therapy possible? ( Rutgeerts, P, 1994) |
"Metastatic cutaneous Crohn's disease, in which noncaseating granulomatous infiltration of the skin occurs at sites separated from the gastrointestinal tract by normal tissue, is the least common dermatological manifestation of Crohn's disease." | 1.29 | Disseminated metastatic cutaneous Crohn's disease. ( Ferguson, A; Hunter, JA; McLaren, K; Peltz, S; Vestey, JP, 1993) |
"In patients with Crohn's disease not taking corticosteroids, IgM lipocortin-I antibody levels were directly related to disease activity scored clinically." | 1.29 | Antibodies to human recombinant lipocortin-I in inflammatory bowel disease. ( Rampton, DS; Smith, SF; Stevens, TR, 1993) |
"Pancreatitis is generally regarded to be an extra-intestinal complication of Crohn's disease unless the duodenum is directly involved." | 1.29 | Crohn's disease associated with pancreatitis of unknown etiology: a case report. ( Arakawa, S; Omata, F; Takahashi, H; Ueno, F, 1993) |
"The development of a toxic hepatitis and dermatitis prompted interruption of the drug." | 1.29 | Sulfasalazine-associated encephalopathy in a patient with Crohn's disease. ( Achten, E; Dewilde, D; Mast, A; Pauwels, W; Schoonjans, R; Van Den Abeele, G; Van Maele, V, 1993) |
"The development of toxic hepatitis and dermatitis prompted interruption of the drug." | 1.29 | Sulfasalazine-associated encephalopathy in a patient with Crohn's disease. ( Achten, E; Dewilde, D; Mast, A; Pauwels, W; Schoonjans, R; Van den Abeele, G; Van Maele, V, 1993) |
" Available evidence indicates that 5-aminosalicylic acid is beneficial in this role, although high dosage is needed." | 1.29 | Maintenance strategies in Crohn's disease. ( Sachar, DB, 1996) |
"In patients with Crohn's disease with ileal involvement, relapse rates were sulphasalazine 9/28 (32." | 1.28 | Is Asacol as effective as sulphasalazine in maintaining remission of Crohn's disease and ulcerative colitis? ( Duncan, A; Nakshabendi, IM; Russell, RI, 1992) |
"55 patients with Crohn's disease and 55 sex- and age-matched healthy controls were studied by nailfold capillary microscopy for evidence of microcirculatory abnormalities." | 1.28 | [Acral vasospasm in Crohn's disease]. ( Affolter, H; Gasser, P; Herzog, U; Schuppisser, JP, 1992) |
"In active ulcerative colitis, A23187 and antihuman IgE induced significantly higher stimulation of PAF synthesis compared to their effects on normal mucosa." | 1.28 | Cytokines and platelet-activating factor in human inflamed colonic mucosa. ( Eliakim, R; Karmeli, F; Ligumsky, M; Rachmilewitz, D; Simon, P, 1992) |
"6-Mercaptopurine is a possible alternative to long-term corticosteroid therapy or surgical treatment in selected patients with severe Crohn's disease." | 1.28 | 6-mercaptopurine therapy in selected cases of corticosteroid-dependent Crohn's disease. ( Greseth, JL; Perrault, J; Tremaine, WJ, 1991) |
"Most patients with concomitant ulcerative colitis and persistently abnormal liver function tests are likely to have PSC." | 1.28 | [Primary sclerosing cholangitis and inflammatory bowel disease]. ( Aadland, E; Elgjo, K; Fausa, O; Kolmannskog, F; Schrumpf, E, 1990) |
" Forty-seven (14%) of 331 patients receiving mesalazine reported adverse events, whereas 33 (23%) of 144 patients receiving sulphasalazine and 23 (19%) of 123 patients receiving placebo reported adverse effects." | 1.28 | Mesalazine: a global safety evaluation. ( Brimblecombe, R, 1990) |
"6-mercaptopurine is an effective long-term therapy for adolescents with intractable Crohn's disease." | 1.28 | Long-term 6-mercaptopurine treatment in adolescents with Crohn's disease. ( Aiges, H; Daum, F; Grancher, K; Markowitz, J; Rosa, J, 1990) |
"Sixteen patients with flare-ups of ulcerative colitis were studied." | 1.28 | [Cryptogenetic ulcerative colitis. Our clinical experience with new therapeutic approaches]. ( Cigala, O; Della Valle, M; Marasco, A; Pancallo, MT, 1990) |
"These four patients (two with Crohn's disease and two with nonspecific colitis) were entered into the second phase of the study." | 1.28 | Does proctosigmoiditis in inflammatory bowel disease presage the imminent onset of symptoms? ( Aiges, H; Daum, F; Kahn, E; Markowitz, J; Rosa, J; Simpser, E, 1989) |
"We report on a case, ulcerative colitis and another of Crohn's disease." | 1.28 | Antimycobacterial chemotherapy in inflammatory bowel disease. ( Celle, G; Gesu, GP; Picciotto, A; Schito, GC; Testa, R; Varagona, G, 1989) |
"An enterovesical fistula in Crohn's disease rarely leads to serious complications and can often be treated successfully with medical therapy alone: by itself, it need not serve as an indication for surgery." | 1.28 | Management of bladder fistulas in Crohn's disease. ( Korelitz, BI; Margolin, ML, 1989) |
"L forms were recovered from 24 of 71 Crohn's disease, 51 of 121 ulcerative colitis, and 2 of 140 control biopsy specimens." | 1.27 | Bacterial L-form isolation from inflammatory bowel disease patients. ( Belsheim, MR; Darwish, RZ; Schieven, B; Watson, WC, 1983) |
"A man with alleged Crohn's disease of the terminal ileum was started on sulfasalazine." | 1.27 | Sulfasalazine pneumonitis. ( Korelitz, BI; Yaffe, BH, 1983) |
"In treatment of Crohn's disease, sulfasalazine has been shown to be effective when disease involves the colon or the colon and small intestine." | 1.27 | Pharmacotherapy of inflammatory bowel disease. Part 1. Sulfasalazine. ( Das, KM, 1983) |
"Although Crohn's disease may decrease fertility, female reproductive ability is normal in UC." | 1.27 | Medical and surgical treatment of inflammatory bowel disease in pregnancy. ( Warsof, SL, 1983) |
"Improvement in Crohn's disease after drug therapy was evaluated in 38 patients with evidence of rectal disease at sigmoidoscopy in whom the rectum later appeared normal." | 1.27 | Response to drug therapy in Crohn's disease: evaluation by rectal biopsy and mucosal cell counts. ( Korelitz, BI; Sommers, SC, 1984) |
"Lipid A is a component common to endotoxins of gram-negative bacteria." | 1.27 | Circulating lipid A antibodies despite absence of systemic endotoxemia in patients with Crohn's disease. ( Eisenburg, J; Galanos, C; Kruis, W; Schussler, P; Weinzierl, M, 1984) |
"Of patients with Crohn's disease whose pregnancies resulted in fetal complications, active IBD was present in 62." | 1.27 | The influence of inflammatory bowel disease and its treatment on pregnancy and fetal outcome. ( Baiocco, PJ; Korelitz, BI, 1984) |
" Feed was infused continuously via a nasoduodenal tube in a dosage of 2600-3200 kcal/day." | 1.27 | Is tube feeding with elemental diets a primary therapy of Crohn's disease? ( Egger-Schödl, M; Lochs, H; Meryn, S; Pötzi, R; Schuh, R; Westphal, G, 1984) |
"As the etiology of Crohn's disease is still unknown, medical as well as surgical treatment has to be symptomatic." | 1.27 | [Crohn disease: I. Possibilities and limits of conservative therapy]. ( Domschke, W, 1984) |
"In 123 out-patients with Crohn's disease the reliability in taking the prescribed therapy with salazosulfapyridine (SASP) was studied over an one year period in a special out-patient clinic." | 1.27 | [Extent of drug compliance in Crohn disease patients--study of a special ambulatory care unit of a university clinic]. ( Degen, I; Ewe, K; Karbach, U, 1984) |
"In 46 patients with confirmed ulcerative colitis pancreas antibodies were demonstrated only twice, in 100 healthy control subjects only 3 times, with titres less than 1 : 100." | 1.27 | [Autoantibodies against the exocrine pancreas and against intestinal goblet cells in the diagnosis of Crohn's disease and ulcerative colitis]. ( Jantschek, G; Normann, D; Otte, M; Stöcker, K; Stöcker, W; Ulrich, S, 1984) |
"Erythema nodosum was found on 11 out of 106 patients with Crohn's disease (10." | 1.27 | [Erythema nodosum and Crohn's disease]. ( Areias, E; García E Silva, L, 1984) |
"6-Mercaptopurine is an effective and useful drug in the treatment of fistulae, as it is in other manifestations of chronic unrelenting Crohn's disease." | 1.27 | Favorable effect of 6-mercaptopurine on fistulae of Crohn's disease. ( Korelitz, BI; Present, DH, 1985) |
"The diagnosis of Crohn's disease with extensive involvement of small intestine and colon was first made in a 12 3/4-year-old girl, now 15 1/2 years old." | 1.27 | [Crohn disease: initial experiences with cyclosporin A in an adolescent girl]. ( Dannecker, G; Malchow, H; Niessen, KH; Ranke, MB, 1985) |
"A 22-year-old man with Crohn's disease of the colon and ileum underwent colonoscopy." | 1.27 | Hepatic portal venous gas after colonoscopy in granulomatous colitis. ( Huycke, A; Moeller, DD, 1985) |
"Pancreatitis was painless (or was associated with moderate and atypical abdominal pain) in four of our six cases; no pancreatic calcification was found in any case; in three patients a total or subtotal exocrine pancreatic insufficiency was evidenced." | 1.27 | Idiopathic pancreatitis associated with inflammatory bowel disease. ( Bitoun, A; Florent, C; Golfain, D; Jian, R; Messing, B; Modigliani, R; Seyrig, JA, 1985) |
"93 children and adolescents with Crohn's disease have been studied." | 1.27 | [Crohn's disease in children and adolescents]. ( Bensoussan, A; Chouraqui, JP; Le Luyer, B; Morin, CL; Roy, CC; Weber, A, 1985) |
"Therefore, Crohn's disease of the esophagus should be considered in the differential diagnosis of biopsy-negative carcinoma of the esophagus in order to avoid major surgery." | 1.27 | Esophageal stricture in Crohn's disease--a case report. ( Iwamatsu, M; Shimizu, T; Yanaga, K; Yukizane, T, 1986) |
"The fertility of 70 men with Crohn's disease and a group of age matched controls were compared." | 1.27 | Male fertility in Crohn's disease. ( Burnell, D; Calcraft, BJ; Mayberry, J; Morris, JS; Rhodes, J, 1986) |
"Increasing incidence of Crohn's disease particularly in childhood and adolescence has made inflammatory bowel disease one of the most important aspects of paediatric gastroenterology." | 1.27 | [Crohn disease in childhood]. ( Bender, SW; Kirchmann, H; Posselt, HG, 1986) |
"Prednisone treatment can sometimes reverse this condition when combined with parenteral nutrition." | 1.27 | [Acute manifestations in Crohn disease and ulcerative colitis. Conservative treatment of acute situations]. ( Goebell, H, 1988) |
"The majority of patients with duodenal Crohn's disease can be treated nonoperatively, with resolution of symptoms and roentgenographic healing of lesions." | 1.26 | Management of Crohn's disease involving the duodenum, including duodenal cutaneous fistula. ( Eliasoph, J; Fitzgibbons, TJ; Green, G; Halls, JM; Silberman, H; Yellin, AE, 1980) |
"No patient with large-intestinal Crohn's disease alone developed more than one recurrence." | 1.26 | Results of operative management of Crohn's disease: A series of 50 patients managed by one surgeon. ( Hughes, ES; McDermott, FT; Milne, BJ; Pihl, EA; Price, AB, 1980) |
" In the fulminant form of the disease the highly dosed application of prednisolone with ease the highly dosed application of prednisolone with parenteral hypercaloric nutrition and the substitution of mineral, protein and blood losses are therapeutically in the first place." | 1.26 | [Ulcerative and granulomatous colitis]. ( Bosseckert, H, 1981) |
"Causal therapy of Crohn's disease up to now cannot be achieved due to the unknown etiology." | 1.26 | [Differentiated therapy in Crohn's disease]. ( Riemann, JF, 1981) |
"Twenty patients with Crohn's disease were treated with metronidazole (Flagyl) or sulfasalazine (Salazopyrin)." | 1.26 | The effect of metronidazole and sulfasalazine on the fecal flora in patients with Crohn's disease. ( Danielsson, D; Järnerot, G; Kjellander, J, 1981) |
"The clinical effect was evaluated by Crohn's Disease Activity Index (CDAI) and serum(s)-orosomucoid value." | 1.26 | Clinical effect of metronidazole and sulfasalazine on Crohn's disease in relation to changes in the fecal flora. ( Danielsson, D; Järnerot, G; Krook, A, 1981) |
"In eleven pregnant patients with ulcerative colitis or Crohn's disease who were treated with sulphasalazine (SASP) the serum concentrations of SASP and sulphapyridine (SP) were measured at delivery." | 1.26 | Placental transfer of sulphasalazine and sulphapyridine and some of its metabolites. ( Esbjörner, E; Into-Malmberg, MB; Järnerot, G, 1981) |
"Pseudomembranous colitis is a potentially life-threatening acute medical problem usually associated with a history of previous antibiotic exposure." | 1.26 | Pseudomembranous colitis. A complication of sulfasalazine therapy in a patient with Crohn's colitis. ( Nichols, TW; Pokorney, BH, 1981) |
"Twelve pregnant patients with ulcerative colitis or Crohn's disease who were being treated with sulphasalazine (SASP) were studied together with their newborn, full-term babies." | 1.26 | Albumin reserve for binding of bilirubin in maternal and cord serum under treatment with sulphasalazine. ( Andersen, S; Brodersen, R; Esbjörner, E; Järnerot, G; Sandström, B, 1981) |
" 2 SASP is poorly absorbed (less than 12%) and the half-time measured in the serum, 10." | 1.26 | The disposition and metabolism of sulphasalazine (salicylazosulphapyridine) in man. ( Aronson, JK; Azadkhan, AK; Truelove, SC, 1982) |
"Etiology and pathogenesis of Crohn's disease, the incidence of which seems to be increasing lately, are still unknown." | 1.26 | [Clinical features of inflammatory bowel disease (author's transl)]. ( Classen, M; Leuschner, U; Strohm, WD, 1982) |
"Apart from two patients with Crohn's disease the antiphlogistic effect of 5-ASA could be proven by endoscopy, histomorphology and (or) radiography with an 86% remission rate and by the improved faecal quality (n = 12)." | 1.26 | [5-Aminosalicylic acid in ulcerative colitis and Crohn's disease (author's transl)]. ( Fischer, C; Heinkel, K; Klotz, U; Maier, K, 1982) |
"27 patients with Crohn's disease were studied." | 1.26 | [(Quality of semen in patients with Crohn's disease) ]. ( Ewe, K; Karbach, U; Schramm, P, 1982) |
"Seventeen patients with ulcerative colitis and three patients with Crohn's disease exhibited different side effects during sulfasalazine therapy." | 1.26 | Desensitization of patients with inflammatory bowel disease to sulfasalazine. ( Das, KM; Taffet, SL, 1982) |
"20 patients with Crohn's disease were entered into a prospective study, after they had been submitted to standard treatment of the acute phase." | 1.26 | [Sugar-free diet as long-term or interval treatment in the remission phase of Crohn disease--a prospective study]. ( Brandes, JW; Körst, HA; Littman, KP, 1982) |
"In a high percentage of patients with ulcerative colitis good results are obtained with conservative therapy, using salazopyridine alone or in combination with cortisone." | 1.26 | [Inflammatory intestinal diseases: ulcerative colitis and Crohn's disease. Early diagnosis and treatment]. ( Belohlavek, D; Koch, H; Morl, M, 1976) |
"Sulfasalazine alone was used in 24 patients, steroids alone were used in four patients, both drugs were used together in 29 patients and azathioprine was added to the drug regimen of five patients." | 1.26 | Anti-inflammatory drug treatment in Crohn's disease. ( Abramson, J; Goldstein, F; Thornton, JJ, 1976) |
"The therapy of Crohn's disease in adolescence must balance the natural disease history of growth suppression, debilitation, and progression against possible drug-related adverse effects on growth and development." | 1.26 | Medical management of Crohn's disease in adolescence. ( Barnes, HV; Bayless, TM; Whittington, PF, 1977) |
"Ileocolitis was the most (52%) and colitis the least (9%) common form of disease with diffuse small bowel or ileal disease each comprising nearly 20% of the study group." | 1.26 | Prognosis in children with Crohn's disease. ( Gryboski, JD; Spiro, HM, 1978) |
"Recurrences were more frequent in patients under than over 31 years of age at their first operation." | 1.26 | [Crohn's disease: course and prognosis in 169 patients (author's transl)]. ( Classen, M; Mörl, M; Zöberlein, HG, 1978) |
"Hemolytic anemia is a well-recognized complication of sulfasalazine treatment." | 1.26 | Hemolytic anemia in patients receiving sulfasalazine. ( Ali, MA; Castelli, M; Goodacre, RL; Hamilton, JD; Seaton, T; Vanderlinden, B, 1978) |
"In 36 unselected patients with ulcerative colitis or Crohn's disease taking 4." | 1.26 | Hemolysis during salicylazosulfapyridine therapy. ( van Elferen, LW; van Hees, PA; van Rossum, JM; van Tongeren, JH, 1978) |
"Recurrent Crohn's disease and that characterized by small bowel obstruction each displayed a characteristic appearance." | 1.26 | Radiographic findings of the National Cooperative Crohn's Disease Study. ( Caruthers, SB; Goldberg, HI; Nelson, JA; Singleton, JW, 1979) |
"Crohn's disease (regional enteritis) is a chronic non-specific inflammatory intestinal disorder of unknown etiology." | 1.25 | [Morbus Crohn (enteritis regionalis)]. ( Phillip, J, 1975) |
"Five patients with Crohn's disease for 4 months to 12 years were treated with metronidazole." | 1.25 | Metronidazole for Crohn's disease. ( Kamme, C; Ursing, B, 1975) |
"Inactive ulcerative colitis still manifested histologic evidence of acute and chronic inflammation, while sigmoidoscopically normal granulomatous colitis biopsies after previous gross rectal disease showed significantly increased macrophages in the lamina propria." | 1.25 | Mucosal-cell counts in ulcerative and granulomatous colitis. ( Korelitz, BI; Sommers, SC, 1975) |
" A single study of serum can determine acetylator phenotype in patients on sulfasalazine therapy without using any other drug for this purpose and may help ascertain dosage and assess side effects." | 1.25 | Acetylation polymorphism of sulfapyridine in patients with ulcerative colitis and Crohn's disease. ( Das, KM; Eastwood, MA, 1975) |
"Patients with proctocolitis and Crohn's disease who were not receiving sulphasalazine had a similar flora which did not differ in any way from the normal." | 1.25 | Effects of sulphasalazine (Salazopyrin) on faecal flora in patients with inflammatory bowel disease. ( Hill, MJ; Lendrum, R; Walker, G; West, B, 1974) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 381 (63.71) | 18.7374 |
1990's | 115 (19.23) | 18.2507 |
2000's | 60 (10.03) | 29.6817 |
2010's | 34 (5.69) | 24.3611 |
2020's | 8 (1.34) | 2.80 |
Authors | Studies |
---|---|
Shin, SJ | 2 |
Collins, MT | 1 |
Murad, H | 1 |
Ahmed, O | 1 |
Alqurashi, T | 1 |
Hussien, M | 1 |
Broekaert, IJ | 3 |
Klein, A | 3 |
Windschall, D | 3 |
Rogalski, B | 3 |
Weller-Heinemann, F | 3 |
Oommen, P | 3 |
Küster, M | 3 |
Foeldvari, I | 3 |
Minden, K | 3 |
Hospach, A | 3 |
Hufnagel, M | 3 |
Berger, T | 3 |
Geikowski, T | 3 |
Quietzsch, J | 3 |
Horneff, G | 3 |
Claytor, J | 1 |
Kumar, P | 1 |
Ananthakrishnan, AN | 1 |
Colombel, JF | 4 |
Agrawal, M | 1 |
Ungaro, RC | 2 |
Momen Majumder, MS | 1 |
Haq, SA | 1 |
Rasker, JJ | 1 |
Brenner, EJ | 1 |
Pigneur, B | 1 |
Focht, G | 1 |
Zhang, X | 1 |
Turner, D | 1 |
Kappelman, MD | 1 |
Ruemmele, FM | 2 |
Jeličić, ML | 1 |
Brusač, E | 1 |
Klarić, DA | 1 |
Nigović, B | 1 |
Turk, N | 1 |
Mornar, A | 1 |
Rizzello, F | 1 |
Calabrese, C | 1 |
Salice, M | 1 |
Calandrini, L | 1 |
Privitera, H | 1 |
Melotti, L | 1 |
Peruzzi, G | 1 |
Dussias, N | 1 |
Belluzzi, A | 1 |
Scaioli, E | 1 |
Decorato, A | 1 |
Siniscalchi, A | 1 |
Filippone, E | 1 |
Laureti, S | 1 |
Rottoli, M | 1 |
Poggioli, G | 1 |
Gionchetti, P | 1 |
Bröms, G | 1 |
Friedman, S | 1 |
Kim, SC | 1 |
Wood, ME | 1 |
Hernandez-Diaz, S | 1 |
Brill, G | 1 |
Bateman, BT | 1 |
Huybrechts, KF | 1 |
Desai, RJ | 1 |
Durando, M | 1 |
Tiu, H | 1 |
Kim, JS | 1 |
Banse, C | 1 |
Armengol-Debeir, L | 1 |
Vittecoq, O | 1 |
Viola, A | 1 |
Caltagirone, AM | 1 |
Campisi, G | 1 |
Guarneri, G | 1 |
Cappello, M | 1 |
Bishnoi, A | 1 |
Banerjee, N | 1 |
Saikia, UN | 1 |
Parsad, D | 1 |
Panaccione, R | 2 |
Steinhart, AH | 2 |
Bressler, B | 1 |
Khanna, R | 1 |
Marshall, JK | 2 |
Targownik, L | 1 |
Afif, W | 1 |
Bitton, A | 1 |
Borgaonkar, M | 1 |
Chauhan, U | 1 |
Halloran, B | 1 |
Jones, J | 1 |
Kennedy, E | 1 |
Leontiadis, GI | 1 |
Loftus, EV | 1 |
Meddings, J | 1 |
Moayyedi, P | 2 |
Murthy, S | 1 |
Plamondon, S | 1 |
Rosenfeld, G | 1 |
Schwartz, D | 1 |
Seow, CH | 2 |
Williams, C | 2 |
Bernstein, CN | 1 |
Jakobiec, FA | 1 |
Rashid, A | 1 |
Lane, KA | 1 |
Kazim, M | 1 |
Zhai, H | 1 |
Liu, A | 1 |
Huang, W | 1 |
Liu, X | 1 |
Feng, S | 1 |
Wu, J | 1 |
Yao, Y | 1 |
Wang, C | 1 |
Li, Q | 1 |
Hao, Q | 1 |
Hu, J | 1 |
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Kristensen, M | 3 |
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Ali, MA | 1 |
Vanderlinden, B | 1 |
Hamilton, JD | 1 |
Castelli, M | 1 |
Seaton, T | 1 |
van Elferen, LW | 1 |
van Rossum, JM | 2 |
Powell-Tuck, J | 1 |
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Mee, AS | 1 |
Clarke, SW | 1 |
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Bernier, JJ | 1 |
Geffroy, Y | 1 |
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Winship, DH | 2 |
Best, WR | 3 |
Becktel, JM | 3 |
Lenk, LF | 1 |
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Law, DH | 2 |
Kelley, ML | 1 |
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Sturdevant, RA | 2 |
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Goldberg, HI | 1 |
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Tilser, P | 1 |
Fixa, B | 1 |
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Zaydlar, K | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Monitoring Serologic Response to SARS-COV-2 / Coronavirus Disease 2019 (COVID-19) in Children, Adolescents, and Young Adults Receiving Biologic Therapies (RECONN)[NCT04838834] | 472 participants (Actual) | Observational | 2020-05-15 | Active, not recruiting | |||
Crohn's Disease European Registry. A Prospective, Observational, Postmarketing Safety Surveillance Registry of Patients Treated With Remicade® or Standard Therapy[NCT00705614] | 2,662 participants (Actual) | Observational | 2003-07-31 | Completed | |||
Identification of Predictive Biomarkers for Response to Biologic Therapies and Tofacitinib in Inflammatory Bowel Disease by Proteomic and Mass Cytometry Approaches[NCT03885713] | Phase 4 | 180 participants (Anticipated) | Interventional | 2019-09-10 | Recruiting | ||
Hypnotherapy for Prevention of Relapse in Ulcerative Colitis: a Randomised, Single-blind, Controlled Clinical Trial[NCT00553163] | 26 participants (Actual) | Interventional | 2007-10-31 | Terminated (stopped due to Unable to recruit sufficient numbers of patinets in the time available) | |||
An Observational Study of the Immunopathogenesis of and Response to Step-Up Inflammatory Bowel Disease Therapy for Hermansky-Pudlak Syndrome-Associated Colitis[NCT00514982] | Phase 2 | 0 participants (Actual) | Interventional | 2007-08-07 | Withdrawn | ||
A Double-blind, Randomized, Placebo-controlled Multicenter Study to Assess the Safety and Efficacy of AST-120 in Mild to Moderately Active Crohn's Patients With Fistulas[NCT00321412] | Phase 3 | 191 participants (Actual) | Interventional | 2006-03-31 | Completed | ||
Fibrin Glue for Perianal Fistulas in Crohn's Disease: a Randomized Controlled Trial[NCT00723047] | Phase 3 | 77 participants (Actual) | Interventional | 2003-11-30 | Completed | ||
The Effect of Sulfasalazine on CRH Levels in Pregnant Women With a History of Pre-Term Birth: A Randomized Controlled Trial[NCT05703425] | Phase 2 | 50 participants (Anticipated) | Interventional | 2023-03-01 | Recruiting | ||
Dexamethasone Versus Methylprednisolone for the Treatment of Active Inflammatory Bowel Disease[NCT00152620] | 40 participants | Interventional | 2004-06-30 | Terminated (stopped due to study completed) | |||
Screening of Nutritional Status and Sarcopenia Among Inflammatory Bowel Disease Patients in Assuit University Hospital[NCT05877209] | 100 participants (Anticipated) | Observational | 2023-06-15 | Not yet recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
The number of participant fatalities was evaluated throughout the study. (NCT00705614)
Timeframe: Up to 5 Years
Intervention | Participants (Number) |
---|---|
Remicade | 30 |
Standard Therapy | 14 |
Switched to Remicade | 4 |
The number of participants with demyelinating neurological disorders was evaluated. Demyelinating neurological disorders were defined as multiple sclerosis, optic neuritis, peripheral syndromes such as peripheral neuropathy, mononeuropathy multipex, cranial neuropathies, Guillain-Barré syndrome, chronic inflammatory demyelinating polyradiculoneuropathy, and transverse myelitis. (NCT00705614)
Timeframe: Up to 5 Years
Intervention | Participants (Number) |
---|---|
Remicade | 4 |
Standard Therapy | 1 |
Switched to Remicade | 0 |
The number of participants wtih hematologic conditions was evaluated. A hematologic condition was defined as thrombocytopenia, neutropenia, pancytopenia, granulocytopenia, leukopenia, or aplastic anemia. (NCT00705614)
Timeframe: Up to 5 Years
Intervention | Participants (Number) |
---|---|
Remicade | 50 |
Standard Therapy | 11 |
Switched to Remicade | 7 |
The number of participants with infusion-related reactions and/or hypersensitivity was evaluated. An infuson-related reaction/hypersensitivity was defined as as an acute reaction, including anaphylactic shock that occurs after the onset of the infusion or within the 1- to 2-hour observation period following the end of the infusion. Delayed hypersensitivity reactions (myalgia and/or arthralgia with fever and rash within 14 days of the infusion) were included. (NCT00705614)
Timeframe: Up to 5 Years
Intervention | Participants (Number) |
---|---|
Remicade | 173 |
Standard Therapy | 1 |
Switched to Remicade | 28 |
The number of participants wtih lymphoproliferative disorders and/or malignancies was evaluated. A lymphoproliferative disorder and /or malignancy included, but was not limited to, lymphoma, gastrointestinal cancer, skin cancer (including basocellular and squamous carcinoma, melanoma) and in situ cervical carcinoma. (NCT00705614)
Timeframe: Up to 5 Years
Intervention | Participants (Number) |
---|---|
Remicade | 49 |
Standard Therapy | 21 |
Switched to Remicade | 8 |
The number of participants with new or worsening congestive heart failure was evaluated throughout the study. (NCT00705614)
Timeframe: Up to 5 Years
Intervention | Participants (Number) |
---|---|
Remicade | 1 |
Standard Therapy | 1 |
Switched to Remicade | 0 |
The number of participants experiencing serious infections was evaluated. Serious infections included, but were not limited to, tuberculosis, opportunistic infections (such as Pneumocystis carinii [PCP] pneumonia, listeriosis, atypical mycobacteria, and histoplasmosis), salmonellosis,and serious viral infections. (NCT00705614)
Timeframe: Up to 5 Years
Intervention | Participants (Number) |
---|---|
Remicade | 132 |
Standard Therapy | 47 |
Switched to Remicade | 18 |
The duration of hospital stays for Crohn's Disease in the prior 6 months was evaluated at each study visit. (NCT00705614)
Timeframe: Up to 5 Years
Intervention | Days (Mean) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Visit 1 (Baseline; n=657,418 ,0) | Visit 2 (n=304,126, 33) | Visit 3 (n=216, 58, 35) | Visit 4 (n=151, 60, 24) | Visit 5 (n=105, 35, 34) | Visit 6 (n=107, 49, 19) | Visit 7 (n=109, 45, 25) | Visit 8 (n=98, 29, 23) | Visit 9 (n=80, 38, 17) | Visit 10 (n=85, 29, 27) | Visit 11 (n=63, 19, 18) | |
Remicade | 12.2 | 14.4 | 14.2 | 12.6 | 11.7 | 10.8 | 10.6 | 9.5 | 12.4 | 10.1 | 11.4 |
Standard Therapy | 10.8 | 12.0 | 9.4 | 8.5 | 9.8 | 13.7 | 10.2 | 16.3 | 6.9 | 8.0 | 8.7 |
Switched to Remicade | NA | 13.0 | 13.5 | 9.1 | 7.1 | 18.3 | 10.0 | 14.7 | 10.7 | 9.0 | 18.1 |
The number of participant hospital stays for Crohn's Disease in the prior 6 months was evaluated at each study visit. (NCT00705614)
Timeframe: Up to 5 Years
Intervention | Hospital Stays (Mean) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Visit 1 (Baseline; n=1539, 1121, 0) | Visit 2 (n=1418, 920, 100) | Visit 3 (n=1334, 827, 152) | Visit 4 (n=1285, 779, 168) | Visit 5 (n=1221, 714, 188) | Visit 6 (n=1170, 665, 208) | Visit 7 (n=1111, 615, 219) | Visit 8 (n=1099, 589, 233) | Visit 9 (n=1046, 562, 229) | Visit 10 (n=1031, 535, 235) | Visit 11 (n=1006, 541, 248) | |
Remicade | 0.7 | 0.3 | 0.3 | 0.2 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 |
Standard Therapy | 0.5 | 0.2 | 0.1 | 0.2 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 |
Switched to Remicade | NA | 0.5 | 0.4 | 0.2 | 0.3 | 0.1 | 0.2 | 0.1 | 0.1 | 0.1 | 0.1 |
The number of participants undergoing surgical procedures for Crohn's Disease in the prior 6 months was evaluated at each study visit. (NCT00705614)
Timeframe: Up to 5 Years
Intervention | Surgical Procedures (Number) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Visit 1 (Basline; n=660, 419, 0) | Visit 2 (n=304, 126, 33) | Visit 3 (n=217, 57, 36) | Visit 4 (n=153, 60, 24) | Visit 5 (n=106, 36, 34) | Visit 6 (n=108, 49, 19) | Visit 7 (n=109, 45, 25) | Visit 8 (n=98, 29, 23) | Visit 9 (n=82, 38, 17) | Visit 10 (n=85, 29, 27) | Visit 11 (n=63, 19, 18) | |
Remicade | 171 | 135 | 121 | 68 | 50 | 49 | 48 | 43 | 38 | 38 | 34 |
Standard Therapy | 81 | 51 | 23 | 16 | 14 | 21 | 20 | 12 | 13 | 13 | 6 |
Switched to Remicade | NA | 7 | 12 | 8 | 14 | 11 | 6 | 7 | 8 | 8 | 8 |
The number of participants with a draining fistula was evaluated at each study visit. (NCT00705614)
Timeframe: Up to 5 Years
Intervention | Participants (Number) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Visit 1 (Baseline; n=1541, 1120, 0) | Visit 2 (n=1420, 920, 100) | Visit 3 (n=1334, 827, 152) | Visit 4 (n=1285, 779, 168) | Visit 5 (n=1221, 714, 188) | Visit 6 (n=1169, 666, 208) | Visit 7 (n=1110, 615, 219) | Visit 8 (n=1097, 588, 233) | Visit 9 (n=1046, 562, 229) | Visit 10 (n=1030, 535, 235) | Visit 11 (n=1006, 541, 248) | |
Remicade | 349 | 211 | 170 | 146 | 125 | 114 | 97 | 105 | 98 | 85 | 87 |
Standard Therapy | 96 | 51 | 41 | 31 | 29 | 26 | 31 | 23 | 32 | 15 | 16 |
Switched to Remicade | NA | 16 | 19 | 12 | 15 | 15 | 15 | 16 | 15 | 20 | 20 |
The participant assessment of overall health status was evaluated at baseline and each study visit. The overall health status questionnaire asked participants to rate their current health status over the prior 24 hours as 1=best possible, 2=much better than average, 3=better than average, 4=average, 5=worse than average, 6=much worse than average, or 7=worst possible. Scores ranged from 1 to 7 with lower scores indicating better health status. (NCT00705614)
Timeframe: Up to 5 Years
Intervention | Score on a Scale (Mean) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Visit 1 (Baseline; n=1526, 1116, 0) | Visit 2 (n=1344, 903, 95) | Visit 3 (n=1280, 809, 146) | Visit 4 (n=1217, 755, 162) | Visit 5 (n=1160, 704, 184) | Visit 6 (n=1110, 649, 202) | Visit 7 (n=1046, 606, 212) | Visit 8 (n=1044, 573, 221) | Visit 9 (n=999, 544, 223) | Visit 10 (n=963, 520, 227) | Visit 11 (n=956, 527, 235) | |
Remicade | 4.3 | 3.3 | 3.2 | 3.2 | 3.1 | 3.1 | 3.1 | 3.1 | 3.1 | 3.0 | 3.0 |
Standard Therapy | 3.9 | 3.3 | 3.1 | 3.0 | 3.1 | 3.0 | 3.0 | 3.0 | 2.9 | 2.8 | 2.8 |
Switched to Remicade | NA | 3.9 | 3.6 | 3.5 | 3.2 | 3.4 | 3.3 | 3.2 | 3.2 | 3.1 | 3.1 |
The Harvey-Bradshaw Index of Crohn's Disease Acitivity was evaluated at each study visit. The Harvey-Bradshaw Index evaluates participants' general health in the day prior in the domains of well being, abdominal pain, number of liquid stools per day, and abdominal mass and complications and was evaluated on the day of the study visit. The score is derived from a 0-4 score for general well being, 0-3 for abdmonial pain, raw score for number of liquid stools per day, 0-3 for abdominal mass, and raw score for complications. The total score is from 0 to infinity, with lower scores indicating better outcomes. (NCT00705614)
Timeframe: Up to 5 Years
Intervention | Score on a Scale (Mean) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Visit 1 (Baseline; n=1505, 1106, 0) | Visit 2 (n=1320, 876, 91) | Visit 3 (n=1250, 785, 143) | Visit 4 (n=1196, 742, 159) | Visit 5 (n=1127, 692, 181) | Visit 6 (n=1070, 647, 199) | Visit 7 (n=1023, 592, 209) | Visit 8 (n=1015, 562, 224) | Visit 9 (n=953, 546, 219) | Visit 10 (n=936, 526, 225) | Visit 11 (n=918, 525, 238) | |
Remicade | 8.2 | 4.1 | 3.7 | 3.8 | 3.7 | 3.6 | 3.6 | 3.6 | 3.6 | 3.4 | 3.4 |
Standard Therapy | 6.2 | 3.8 | 3.5 | 3.2 | 3.4 | 3.1 | 3.0 | 3.2 | 2.9 | 2.7 | 2.7 |
Switched to Remicade | NA | 6.0 | 4.4 | 4.8 | 4.9 | 4.5 | 4.1 | 4.1 | 4.4 | 4.3 | 4.2 |
The participant work/daily activity status score was evaluated at each study visit. The work/daily activity questionnaire asked participants to rate their level of daily functioning on a scale of 1 to 10 with a lower score indicating less of an impact of Crohn's disease on work or daily life functioning. (NCT00705614)
Timeframe: Up to 5 Years
Intervention | Score on a Scale (Mean) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Visit 1 (Baseline; n=1496, 1108, 0) | Visit 2 (n=1316, 895, 94) | Visit 3 (n=1235, 797, 143) | Visit 4 (n=1192, 738, 159) | Visit 5 (n=1128, 694, 179) | Visit 6 (n=1077, 638, 201) | Visit 7 (n=1030, 601, 207) | Visit 8 (n=1025, 571, 221) | Visit 9 (n=982, 542, 222) | Visit 10 (n=934, 514, 225) | Visit 11 (n=925, 521, 235) | |
Remicade | 5.9 | 4.2 | 3.8 | 3.6 | 3.4 | 3.3 | 3.2 | 3.3 | 3.3 | 3.1 | 3.2 |
Standard Therapy | 4.9 | 3.7 | 3.2 | 2.9 | 3.0 | 2.7 | 2.8 | 2.7 | 2.6 | 2.4 | 2.4 |
Switched to Remicade | NA | 5.5 | 4.8 | 4.3 | 4.0 | 3.9 | 3.6 | 3.5 | 3.5 | 3.6 | 3.6 |
Measure of anxiety, HADS Hospital anxiety and depression scale. HADS questionnaire consists of a 14 question validated questionnaire, developed to measure anxiety and depression in the hospital setting. Each item is answered by the patient on a four point (0-3) response category so the possible scores range from 0 (minimum) to 21 (maximum) for anxiety and 0 (minimum) to 21 (maximum) for depression. Higher scores indicate worse outcome, (NCT00553163)
Timeframe: 13 weeks
Intervention | score on a scale (Median) |
---|---|
UC Patients Given Gut-focussed Hpynotherapy | 7 |
UC Patients Given Control Educational Sessions | 10 |
Measure of depression. Each item is answered by the patient on a four point (0-3) response category so the possible scores range from 0 to 21 for anxiety and 0 to 21 for depression. Each item is answered by the patient on a four point (0-3) response category so the possible scores range from 0 (minimum) to 21 (maximum) for anxiety and (minimum) to 21 (maximum) for depression. Higher scores worse outcome. (NCT00553163)
Timeframe: 13 weeks
Intervention | units on a scale (Median) |
---|---|
UC Patients Given Gut-focussed Hypnotherapy | 1.5 |
UC Patients Given Control Educational Sessions | 4 |
IBDQ (standard measure of IBD patients' Quality of life (QoL) (Irvine et al 1982 approx). The IBDQ is a validated and reliable tool to measure of health-related quality of life in adult patients with IBD. The questionnaire consists of 32 questions scored in four domains: bowel symptoms, emotional health, systemic systems and social function. Scores range from 1 (poorest QoL) to 7 (best QoL). Higher scores indicate better QoL. Lowest score 7, highest score 224. (NCT00553163)
Timeframe: 13 weeks
Intervention | units on a scale (Median) |
---|---|
UC Patients Given Gut-focussed Hypnotherapy | 195 |
UC Patients Given Control Educational Sessions | 192 |
Measure of recent psychological stress. THE PSQ R consists of a 30 question questionnaires: recent, in which the statements used apply to the last month in which used statements apply to the last two years (Appendix 1.3). The score for both recent and general stress levels were stated as the PSQ index ranging from 0 (non-stressed) to 0.99 (highly stressed). Higher scores indicate worse outcome. (NCT00553163)
Timeframe: 13 weeks
Intervention | units on a scale (Median) |
---|---|
UC Patients Given Gut-focussed Hypnotherapy | 0.3 |
UC Patients Given Control Educational Sessions | 0.4 |
The number of patients suffering a relapse was compared between the two treatment groups, and was the primary outcome parameter of this study. (NCT00553163)
Timeframe: 1 year
Intervention | Participants (Count of Participants) |
---|---|
UC Patients Given Gut-focussed Hypnotherapy | 8 |
UC Patients Given Control Educational Sessions | 7 |
123 reviews available for sulfasalazine and Colitis, Granulomatous
Article | Year |
---|---|
Mild Crohn's Disease: Definition and Management.
Topics: Anti-Bacterial Agents; Budesonide; Crohn Disease; Enteral Nutrition; Humans; Remission Induction; Su | 2023 |
Effectiveness of vedolizumab for Crohn's disease with spondyloarthritis in fail with two TNF blocking agents.
Topics: Adrenal Cortex Hormones; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Crohn Dis | 2018 |
Advances in Pediatric Inflammatory Bowel Disease.
Topics: Adalimumab; Adolescent; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibodies, Monoclonal, Huma | 2016 |
Aminosalicylates for induction of remission or response in Crohn's disease.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Budesonide; Crohn Disease; Delayed-Ac | 2016 |
Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease.
Topics: Adult; Antimetabolites; Azathioprine; Crohn Disease; Glucocorticoids; Humans; Immunosuppressive Agen | 2016 |
Comparative Effectiveness of Mesalamine, Sulfasalazine, Corticosteroids, and Budesonide for the Induction of Remission in Crohn's Disease: A Bayesian Network Meta-analysis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Bayes Theorem; Budesonide; Comparative Effectiven | 2017 |
[From research to clinic: The case of Crohn's disease and Tumor Necrosis Factor].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Crohn Disease; Human | 2000 |
Crohn's disease during etanercept therapy in juvenile idiopathic arthritis: a case report and review of the literature.
Topics: Adalimumab; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Art | 2010 |
Pancreatitis in inflammatory bowel diseases.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Colitis, Ulcerative; Crohn Dis | 2010 |
[Pulmonary manifestations of inflammatory bowel disease].
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Bronchoscopy; Chest Pain; Colitis, Ulcerative; Cough; | 2010 |
Aminosalicylates for induction of remission or response in Crohn's disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Budesonide; Crohn Disease; Humans; Mesalamine; Randomized C | 2010 |
Efficacy of 5-aminosalicylates in Crohn's disease: systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Humans; Mesalamine; Randomized Controlled Tr | 2011 |
Update on the management of Crohn's disease.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies | 2011 |
[5-aminosalicylic acid for induction of remission or clinical response in Crohn's disease--a survey of a Cochrane review].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Evidence-Based Medicine; Humans; Mesalamine; | 2011 |
Diagnosis, prevention and treatment of postoperative Crohn's disease recurrence.
Topics: Adalimumab; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; | 2012 |
Results of the 2nd scientific workshop of the ECCO (III): basic mechanisms of intestinal healing.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, | 2012 |
Inflammatory bowel disease (Crohn's disease) in a Spanish patient with pars plana exudates: report of a new case and review of the literature.
Topics: Adult; Anti-Inflammatory Agents; Crohn Disease; Drug Combinations; Drug Therapy, Combination; Exudat | 2002 |
Recent developments in inflammatory bowel disease.
Topics: Adjuvants, Immunologic; Antibodies, Monoclonal; Colitis, Ulcerative; Crohn Disease; Cyclosporine; Ga | 2002 |
[Conservative therapy of inflammatory bowel diseases].
Topics: Acute Disease; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Chro | 2002 |
The state of the art in the management of inflammatory bowel disease.
Topics: Administration, Oral; Adrenal Cortex Hormones; Colitis, Ulcerative; Crohn Disease; Cyclosporine; Dos | 2003 |
Review article: medical treatment of mild to moderately active Crohn's disease.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Monoclonal; Colonic Diseases; Crohn Diseas | 2003 |
Review article: maintenance treatment of Crohn's disease.
Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, | 2003 |
[A case of Crohn's disease complicated with hepatocellular carcinoma].
Topics: Adult; Anti-Inflammatory Agents; Carcinoma, Hepatocellular; Crohn Disease; Drug Combinations; Drug T | 2003 |
Review article: mild to moderate Crohn's disease--defining the basis for a new treatment algorithm.
Topics: Administration, Topical; Algorithms; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammat | 2003 |
Controversies with aminosalicylates in inflammatory bowel disease.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Chemopreventi | 2004 |
Oral 5-aminosalicylic acid for maintenance of medically-induced remission in Crohn's Disease.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Humans; Mesalamine; Re | 2005 |
The use of medications for inflammatory bowel disease during pregnancy and nursing.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; B | 2005 |
Systematic review: the use of mesalazine in inflammatory bowel disease.
Topics: Acute Disease; Administration, Oral; Administration, Topical; Anti-Inflammatory Agents, Non-Steroida | 2006 |
Systematic review: the use of mesalazine in inflammatory bowel disease.
Topics: Acute Disease; Administration, Oral; Administration, Topical; Anti-Inflammatory Agents, Non-Steroida | 2006 |
Systematic review: the use of mesalazine in inflammatory bowel disease.
Topics: Acute Disease; Administration, Oral; Administration, Topical; Anti-Inflammatory Agents, Non-Steroida | 2006 |
Systematic review: the use of mesalazine in inflammatory bowel disease.
Topics: Acute Disease; Administration, Oral; Administration, Topical; Anti-Inflammatory Agents, Non-Steroida | 2006 |
Clinical aspects of ulcerative colitis in mainland China.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; China; Colitis, Ulcerative; Crohn Dis | 2006 |
Pharmacogenetics in inflammatory bowel disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Colitis, Ulcerative; | 2006 |
[Ulcerous colitis and Crohn's disease in members of one family: case description and review of literature].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Colonoscopy; Crohn Disease; Humans; Ma | 2006 |
Drug insight: aminosalicylates for the treatment of IBD.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Chemoprevention; Colitis, Ulcerative; | 2007 |
[Pathogenesis and treatment of intestinal Behçet's disease].
Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal; Behcet Syndrome; Colchicine; Colitis, Ulcerative; C | 2007 |
Observations on the medical treatment of inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Clinical Trials as Topic; Colitis, Ulcerative; Crohn | 1980 |
[Medical treatment of Crohn disease].
Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Child; Crohn Disease; | 1980 |
A critical survey of controlled studies in the treatment of ulcerative colitis and Crohn's disease.
Topics: BCG Vaccine; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Cromolyn Sodium; Glucocor | 1980 |
[Dietary and drug therapy of intestinal disease].
Topics: Aerophagy; Anti-Inflammatory Agents; Atropine; beta-Galactosidase; Cathartics; Colitis, Ulcerative; | 1980 |
[Therapy of Crohn's disease in childhood].
Topics: Azathioprine; Child; Crohn Disease; Doxycycline; Drug Therapy, Combination; Humans; Metronidazole; P | 1981 |
Inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Adult; Child; Colectomy; Colitis, Ulcerative; Crohn Disease; Female; Humans | 1982 |
The immunology of inflammatory bowel disease.
Topics: Azathioprine; Colitis, Ulcerative; Complement System Proteins; Crohn Disease; Humans; Hypersensitivi | 1982 |
Inflammatory bowel disease--where are we? A review of ulcerative colitis and Crohn's disease, highlighting the problems of aetiology, epidemiology, clinical factors and management.
Topics: Adenocarcinoma; Adrenal Cortex Hormones; Colectomy; Colitis, Ulcerative; Colonic Neoplasms; Crohn Di | 1982 |
Inflammatory bowel disease and pregnancy.
Topics: Abortion, Spontaneous; Adolescent; Adrenocorticotropic Hormone; Adult; Colitis, Ulcerative; Crohn Di | 1982 |
Fertility, sterility, and pregnancy in chronic inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Colitis, Ulcerative; Crohn Disease; Female; Fertility; Humans; Infant, Newb | 1982 |
[Ulcerative rectocolitis: current clinical and therapeutic concepts].
Topics: Adrenal Cortex Hormones; Colectomy; Colitis, Ulcerative; Colonic Neoplasms; Colposcopy; Crohn Diseas | 1982 |
Medical treatment of ulcerative colitis and Crohn's disease.
Topics: Adrenal Cortex Hormones; Colitis, Ulcerative; Crohn Disease; Female; Humans; Pregnancy; Pregnancy Co | 1983 |
Sulfasalazine. Pharmacology, clinical use, toxicity, and related new drug development.
Topics: Aminosalicylic Acids; Animals; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Drug In | 1984 |
[Crohn disease and ulcerative colitis. Frequency, familial occurrence and pregnancy course].
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Chromosome Mapping; Colitis, Ulcerati | 1984 |
[Pathogenesis of chronic inflammatory bowel diseases].
Topics: Adrenal Cortex Hormones; Adult; Cell Membrane Permeability; Child; Colitis, Ulcerative; Crohn Diseas | 1983 |
[Cryptogenetic inflammatory diseases of the intestine and pregnancy. Reality and prejudices].
Topics: Adrenal Cortex Hormones; Azathioprine; Colitis, Ulcerative; Crohn Disease; Female; Humans; Postopera | 1993 |
Maintenance of symptomatic remission in patients with Crohn's disease.
Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Azathioprine; Clinical Trials as Topic; Crohn Disease | 1993 |
Rolling review: inflammatory bowel disease.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Clinical Trials as Topic; Colitis, Ulcerative; Crohn | 1993 |
[Current focus on inflammatory intestinal diseases: Crohn's disease and ulcero-hemorrhagic rectocolitis].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aminosalicylic Acids; Child; Colitis, Ulcerative; | 1993 |
Peristomal pyoderma gangrenosum and inflammatory bowel disease.
Topics: Adolescent; Adult; Biopsy; Colostomy; Crohn Disease; Dapsone; Female; Humans; Ileostomy; Inflammatio | 1994 |
Medical management of Crohn's disease in childhood.
Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Child; Combined Modality Therapy; Crohn Disease; Huma | 1994 |
Sulfasalazine and mesalazine for the maintenance therapy of Crohn's disease: a meta-analysis.
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Crohn Disease; Humans; Mesalamine; Sulfasalazine | 1994 |
[Crohn's disease with isolated vulvar localization and pregnancy. A case report].
Topics: Adult; Crohn Disease; Drug Therapy, Combination; Female; Humans; Metronidazole; Pregnancy; Pregnancy | 1994 |
[The role of cytokines in the pathogenesis of inflammatory intestinal diseases].
Topics: Colitis, Ulcerative; Crohn Disease; Cytokines; Humans; Interferon-gamma; Interleukin-1; Interleukin- | 1994 |
[Local or systemic treatment of inflammatory bowel diseases?].
Topics: Administration, Oral; Administration, Rectal; Administration, Topical; Adrenal Cortex Hormones; Amin | 1993 |
[Chronic idiopathic enterocolitis and pregnancy. Reciprocal repercussions and treatment].
Topics: Abortion, Spontaneous; Adult; Aminosalicylic Acids; Chronic Disease; Colectomy; Colitis, Ulcerative; | 1993 |
[Crohn disease and ulcerative colitis--newer therapeutic approaches].
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Colitis, Ulcerative; Crohn Disease; Glucocorticoids; | 1993 |
Localized epidermolysis bullosa acquisita of the esophagus in a patient with Crohn's disease.
Topics: Adult; Anti-Inflammatory Agents; Crohn Disease; Epidermolysis Bullosa Acquisita; Esophageal Diseases | 1996 |
Massive secretory diarrhea and pseudo-obstruction as the initial presentation of Crohn's disease.
Topics: Anti-Inflammatory Agents; Crohn Disease; Diarrhea; Humans; Intestinal Pseudo-Obstruction; Male; Metr | 1996 |
Review article: the medical management of Crohn's disease.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Clinical Trials as Topic; Crohn Disease; Enteral Nu | 1996 |
[Pericarditis in chronic inflammatory bowel disease: underlying disease or side effects of therapy? Clinical problem solving].
Topics: Adult; Crohn Disease; Drug Combinations; Female; Glucosamine; Humans; Male; Myocarditis; Pericardial | 1996 |
[Myositis--a rare complication of Crohn disease].
Topics: Azathioprine; Biopsy; Crohn Disease; Drug Therapy, Combination; Humans; Male; Methylprednisolone; Mi | 1996 |
Inflammatory bowel disease: short- and long-term treatments.
Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, | 1998 |
The treatment of inflammatory bowel disease in children.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Child; Colitis, Ulcerative; Crohn Disease; Fe | 1998 |
Aminosalicylates for active disease and in the maintenance of remission in Crohn's disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Glucocorticoids; Humans; Mesalamine; Meta-An | 1998 |
[Histopathologic diagnosis of the activity of chronic inflammatory bowel disease. Evaluation of the effect of drug treatment. Use of histological scores].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Biopsy; Colitis, Ulc | 1999 |
Medical therapy to reduce postoperative Crohn's disease recurrence.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Glucocorticoids; Huma | 2000 |
[Crohn's disease].
Topics: Antibodies; Crohn Disease; Diagnosis, Differential; Humans; Macrophages; Nutritional Support; Predni | 2000 |
Conventional treatment of Crohn's disease: objectives and outcomes.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathioprin | 2001 |
Inflammatory bowel disease and pregnancy.
Topics: Adult; Aminosalicylic Acids; Anti-Bacterial Agents; Colitis, Ulcerative; Crohn Disease; Female; Fert | 2001 |
[Is the lung a target organ in inflammatory bowel disease?].
Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bronchial Diseases | 2001 |
New steroids and new salicylates in inflammatory bowel disease: a critical appraisal.
Topics: Acute Disease; Aspirin; Beclomethasone; Budesonide; Colitis, Ulcerative; Crohn Disease; Drug Therapy | 2002 |
[Therapy of Crohn's disease].
Topics: Adult; Aged; Analgesics; Crohn Disease; Humans; Immunosuppressive Agents; Middle Aged; Parasympathol | 1977 |
Drug treatment of inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Bacterial Agents; Antidiarrheals; Azathio | 1979 |
Inflammatory bowel disease in children and adolescents.
Topics: Adolescent; Adrenal Cortex Hormones; Biopsy; Child; Colitis, Ulcerative; Crohn Disease; Diagnosis, D | 1979 |
The protean manifestations of Crohn's disease.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Arthritis; Azathioprine; Child; Colectomy; Colitis, | 1975 |
Inflammatory disease of the colon: ulcerative colitis and Crohn's colitis.
Topics: Adrenal Cortex Hormones; Adult; Anus Diseases; Arthritis; Azathioprine; Child, Preschool; Colectomy; | 1975 |
[Long-term therapy and timing of surgical intervention in ulcerative colitis and Crohn disease].
Topics: Acute Disease; Aminosalicylic Acids; Colitis, Ulcerative; Combined Modality Therapy; Crohn Disease; | 1992 |
[Drug therapy of chronic inflammatory bowel disease--reliable standards and new developments].
Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Azathioprine; Colitis, Ulcerative; Crohn Disease; Hum | 1992 |
Maintenance treatment for Crohn's disease: has the time arrived?
Topics: Aminosalicylic Acids; Azathioprine; Crohn Disease; Drug Administration Schedule; Drug Therapy, Combi | 1992 |
Sulfasalazine and 5-ASA compounds.
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Drug Combination | 1992 |
[Significance of free oxygen radicals for pathogenesis of chronic inflammatory disease].
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Drug Combinations; Free Radicals; Glucosam | 1992 |
Therapeutic interventions in gastrointestinal disease based on an understanding of inflammatory mediators.
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Cytokines; Eicosapentaenoic Acid; Fish Oil | 1992 |
Medical therapy in Crohn's disease.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Clinical Trials as Topic; Crohn Disease; Humans; Imm | 1992 |
Crohn's disease of the small bowel.
Topics: Anti-Inflammatory Agents; Crohn Disease; Duodenitis; Humans; Ileitis; Intestinal Obstruction; Steroi | 1991 |
Review article: the pharmacological implications of leucocyte-endothelial cell interactions in Crohn's disease.
Topics: Adrenal Cortex Hormones; Cell Adhesion; Crohn Disease; Cyclosporins; Endothelium; Humans; Leukocytes | 1991 |
[Conservative therapy of Crohn disease--reliable measures based on clinical studies].
Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Anti-Bacterial Agents; Crohn Disease; Humans; Immunos | 1991 |
Involvement of oxygen-derived free radicals in the pathogenesis of chronic inflammatory bowel disease.
Topics: Colitis, Ulcerative; Crohn Disease; Eicosanoids; Free Radicals; Glucocorticoids; Humans; Intestinal | 1991 |
[New developments in the treatment of inflammatory bowel diseases. What is certain?].
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Humans; Immunosu | 1990 |
Medical management of Crohn's disease.
Topics: Aminosalicylic Acids; Crohn Disease; Female; Humans; Immunosuppression Therapy; Metronidazole; Pregn | 1990 |
Cutaneous polyarteritis nodosa associated with Crohn's disease. Report and review of the literature.
Topics: Adrenal Cortex Hormones; Adult; Crohn Disease; Cyclophosphamide; Female; Humans; Ileum; Polyarteriti | 1990 |
The role of mesalazine in Crohn's disease.
Topics: Aminosalicylic Acids; Crohn Disease; Humans; Mesalamine; Sulfasalazine | 1990 |
Phagocytes, toxic oxygen metabolites and inflammatory bowel disease: implications for treatment.
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Colon; Crohn Disease; Humans; Mesalamine; Oxygen; Phagocy | 1990 |
Sulfasalazine therapy in inflammatory bowel disease.
Topics: Chemical Phenomena; Chemistry; Colitis, Ulcerative; Crohn Disease; Drug Interactions; Humans; Sulfas | 1989 |
Topical salicylate therapy (4-ASA and 5-ASA enemas).
Topics: Administration, Topical; Aminosalicylic Acid; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disea | 1989 |
Antibiotics and inflammatory bowel diseases.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Colitis, Ulcerative; Croh | 1989 |
Drug treatment and formation of eicosanoids in patients with chronic inflammatory bowel disease.
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Humans; Inflammatory Bowel Diseases; Leuko | 1989 |
[Prevention of recurrence of chronic inflammatory bowel diseases].
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Humans; Immunosu | 1989 |
Regional enteritis.
Topics: Adolescent; Adult; Azathioprine; Crohn Disease; Diagnosis, Differential; Humans; Intestinal Absorpti | 1985 |
Salazopyrin and its newer analogues in the treatment of inflammatory bowel disease.
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Double-Blind Method; Drug Combinations; Dr | 1985 |
Management of medical problems in pregnancy--inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Azathioprine; Colitis, Ulcerative; Crohn Disease; Delivery, Obstetric; Fema | 1985 |
Current status of drug therapy for inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Administration Sched | 1985 |
Sulfasalazine and new analogues.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Clinical Trials as Topic; Colitis, Ulcerative; C | 1986 |
Cell-mediated immunity in gastrointestinal disease.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Antilymphocyte Serum; B-Lymphocytes; Celiac Diseas | 1986 |
Chronic inflammatory bowel disease.
Topics: Child; Colectomy; Colitis, Ulcerative; Crohn Disease; Enema; Food, Formulated; Humans; Prednisolone; | 1986 |
Inflammatory bowel disease in pregnancy: a review.
Topics: Abortion, Spontaneous; Adrenal Cortex Hormones; Azathioprine; Colitis, Ulcerative; Crohn Disease; Fe | 1986 |
Sulphasalazine: a review of 40 years' experience.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Diseas | 1986 |
Current management of inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Aza Compounds; Colitis, Ulcerative; Combined Modality Therapy; Crohn Diseas | 1987 |
[New salazosulfapyridine derivatives. Progress in the treatment of chronic inflammatory diseases of the intestines?].
Topics: Administration, Oral; Administration, Rectal; Chronic Disease; Colitis, Ulcerative; Crohn Disease; D | 1987 |
Oral 5-aminosalicylic acid preparations in treatment of inflammatory bowel disease. An update.
Topics: Administration, Oral; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Dis | 1987 |
Inflammatory bowel disease in children.
Topics: Barium Sulfate; Child; Colitis, Ulcerative; Combined Modality Therapy; Crohn Disease; Diagnosis, Dif | 1988 |
Medical treatment of inflammatory bowel disease: new therapies, new drugs.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Crohn Disease; F | 1987 |
[New developments and trends in the drug therapy of chronic inflammatory bowel diseases].
Topics: Colitis, Ulcerative; Crohn Disease; Glucocorticoids; Humans; Sulfasalazine | 1988 |
[Therapy of chronic inflammatory bowel diseases. Clinical aspects and therapy of drug-induced side effects].
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Glucocorticoids; Humans; Immunosuppressive | 1988 |
[Inhibition of intestinal leukotriene formation as a possible mechanism of action of sulfasalazine, 5-aminosalicylic acid and 4-aminosalicylic acid].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Colitis, Ulcerative; Crohn Disease; Humans; Inte | 1988 |
Inflammatory bowel disease in the adolescent patient.
Topics: Adolescent; Adrenal Cortex Hormones; Animals; Colitis, Ulcerative; Colonic Diseases; Crohn Disease; | 1973 |
Ulcerative colitis. Selected clinical, diagnostic and therapeutic aspects. II.
Topics: Adrenocorticotropic Hormone; Adult; Chronic Disease; Colectomy; Colitis, Ulcerative; Cortisone; Croh | 1973 |
Inflammatory bowel disease.
Topics: Adrenocorticotropic Hormone; Anti-Bacterial Agents; Azathioprine; Colitis, Ulcerative; Crohn Disease | 1974 |
[What is secured in the therapy of chronic inflammatory colonic diseases?].
Topics: Administration, Topical; Amebiasis; Azathioprine; Chronic Disease; Colitis; Colitis, Ulcerative; Col | 1974 |
Early or late operation in the treatment of Crohn's disease.
Topics: Adrenal Cortex Hormones; Crohn Disease; Humans; Postoperative Complications; Sulfasalazine; Time Fac | 1971 |
73 trials available for sulfasalazine and Colitis, Granulomatous
Article | Year |
---|---|
Lifestyle-related disease in Crohn's disease: relapse prevention by a semi-vegetarian diet.
Topics: Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Diet, Vegetarian; Fema | 2010 |
Mud-bath treatment in spondylitis associated with inflammatory bowel disease--a pilot randomised clinical trial.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colitis, Ulcerative; Combined Modality Ther | 2007 |
Observations on the medical treatment of inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Clinical Trials as Topic; Colitis, Ulcerative; Crohn | 1980 |
The National Cooperative Crohn's Disease Study.
Topics: Azathioprine; Clinical Trials as Topic; Crohn Disease; Humans; Placebos; Prednisone; Prognosis; Sulf | 1980 |
Treatment of Crohn's disease with 6-mercaptopurine. A long-term, randomized, double-blind study.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Clinical Trials as Topic; Crohn Disease; Double-Bl | 1980 |
Treatment of Crohn's disease with 6-mercaptopurine. A long-term, randomized, double-blind study.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Clinical Trials as Topic; Crohn Disease; Double-Bl | 1980 |
Treatment of Crohn's disease with 6-mercaptopurine. A long-term, randomized, double-blind study.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Clinical Trials as Topic; Crohn Disease; Double-Bl | 1980 |
Treatment of Crohn's disease with 6-mercaptopurine. A long-term, randomized, double-blind study.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Clinical Trials as Topic; Crohn Disease; Double-Bl | 1980 |
How should we treat Crohn's disease?
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Clinical Trials as Topic; Crohn Disease; Double-Blind | 1980 |
No cytogenic effect of metronidazole.
Topics: Chromosome Aberrations; Clinical Trials as Topic; Crohn Disease; Humans; Metronidazole; Random Alloc | 1980 |
A critical survey of controlled studies in the treatment of ulcerative colitis and Crohn's disease.
Topics: BCG Vaccine; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Cromolyn Sodium; Glucocor | 1980 |
Therapeutic efficacy of sulfasalazine and its metabolites in patients with ulcerative colitis and Crohn's disease.
Topics: Adult; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Humans; M | 1980 |
Azathioprine has a very limited role in the treatment of Crohn's disease.
Topics: Azathioprine; Clinical Trials as Topic; Crohn Disease; Double-Blind Method; Humans; Prednisone; Rand | 1981 |
Effect of sulphasalazine in patients with active Crohn's disease: a controlled double-blind study.
Topics: Adolescent; Adult; Clinical Trials as Topic; Crohn Disease; Double-Blind Method; Female; Humans; Mal | 1981 |
Intestinal lavage in the treatment of Crohn's disease: a pilot study.
Topics: Antacids; Cortisone; Crohn Disease; Dietary Fiber; Female; Humans; Jejunum; Parenteral Nutrition; Su | 1982 |
A comparative study of metronidazole and sulfasalazine for active Crohn's disease: the cooperative Crohn's disease study in Sweden. I. Design and methodologic considerations.
Topics: Adult; Animals; Clinical Trials as Topic; Crohn Disease; Double-Blind Method; Female; Humans; Male; | 1982 |
A comparative study of metronidazole and sulfasalazine for active Crohn's disease: the cooperative Crohn's disease study in Sweden. II. Result.
Topics: Adult; Anorexia; Blood Sedimentation; Clinical Trials as Topic; Crohn Disease; Double-Blind Method; | 1982 |
Metronidazole in Crohn's disease.
Topics: Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Double-Blind Method; Humans; Metronida | 1982 |
Short-term systemic prophylaxis with cefoxitin and doxycycline in colorectal surgery. A prospective, randomized study.
Topics: Adult; Aged; Cefoxitin; Colonic Diseases; Crohn Disease; Doxycycline; Female; Humans; Male; Middle A | 1982 |
Metronidazole exhibits no clastogenic activity in a double-blind cross-over study on Crohn's patients.
Topics: Adolescent; Adult; Chromosome Aberrations; Chromosomes; Crohn Disease; Female; Humans; Male; Metroni | 1982 |
[Are there new viewpoints in the treatment of Crohn disease?].
Topics: Clinical Trials as Topic; Crohn Disease; Double-Blind Method; Drug Combinations; Drug Therapy, Combi | 1982 |
[Basic diet in Crohn's disease].
Topics: Adolescent; Adrenal Cortex Hormones; Blood Proteins; Blood Sedimentation; Body Weight; Child; Crohn | 1983 |
Disposition of 5-aminosalicylic acid, the active metabolite of sulphasalazine, in man.
Topics: Adult; Aged; Aminosalicylic Acids; Bile; Biliary Tract Diseases; Colitis, Ulcerative; Crohn Disease; | 1983 |
European Cooperative Crohn's Disease Study (ECCDS): results of drug treatment.
Topics: Adult; Clinical Trials as Topic; Crohn Disease; Double-Blind Method; Drug Therapy, Combination; Euro | 1984 |
Desensitization to sulfasalazine after hypersensitivity reactions in patients with inflammatory bowel disease.
Topics: Clinical Trials as Topic; Colitis; Colitis, Ulcerative; Crohn Disease; Desensitization, Immunologic; | 1984 |
Treatment of Crohn's disease.
Topics: Adrenal Cortex Hormones; Clinical Trials as Topic; Crohn Disease; Humans; Random Allocation; Sulfasa | 1984 |
Sulfasalazine. Pharmacology, clinical use, toxicity, and related new drug development.
Topics: Aminosalicylic Acids; Animals; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Drug In | 1984 |
Renal function was not impaired by treatment with 5-aminosalicylic acid in rats and man.
Topics: Aminosalicylic Acids; Animals; Clinical Trials as Topic; Crohn Disease; Humans; Kidney; Male; Mesala | 1984 |
[Radical operation and recurrence prevention with azulfidine in Crohn disease: a prospective multicenter study--initial results].
Topics: Clinical Trials as Topic; Combined Modality Therapy; Crohn Disease; Humans; Postoperative Complicati | 1984 |
[Results of treatment with sulfasalazine in the American Multicenter Study on the treatment of Crohn disease (National Cooperative Crohn's Disease Study)].
Topics: Clinical Trials as Topic; Crohn Disease; Double-Blind Method; Drug Therapy, Combination; Humans; Pre | 1981 |
[Effectiveness of Azulfidine/Salazopyrin in the postoperative prevention of recurrence in Crohn disease].
Topics: Clinical Trials as Topic; Colectomy; Crohn Disease; Double-Blind Method; Humans; Postoperative Compl | 1981 |
[Further controlled studies on the effectiveness of salazosulfapyridine in the treatment of Crohn disease].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Crohn Disease; Double-Blind Method; Humans; Middl | 1981 |
Insulin like growth factor-I, insulin like growth factor binding protein-1, and insulin in childhood Crohn's disease.
Topics: Adolescent; Carrier Proteins; Child; Child, Preschool; Crohn Disease; Female; Growth Disorders; Huma | 1993 |
Management of perianal Crohn's disease. Results of a multicenter study in Italy.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Aminosalicylic Acids; Anti-Bact | 1995 |
Home elemental enteral hyperalimentation (HEEH) for the maintenance of remission in patients with Crohn's disease.
Topics: Adult; Combined Modality Therapy; Crohn Disease; Energy Intake; Enteral Nutrition; Female; Follow-Up | 1993 |
Assessment of the prevalence of infection with Helicobacter pylori in patients with inflammatory bowel disease.
Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Breath Tests; Colitis, Ulcera | 2000 |
Interaction between azathioprine and aminosalicylates: an in vivo study in patients with Crohn's disease.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Biomarkers; Crohn Disease; Drug | 2002 |
[7 clinics evaluate metronidazole therapy in Crohn's disease].
Topics: Clinical Trials as Topic; Crohn Disease; Drug Evaluation; Humans; Metronidazole; Sulfasalazine; Swed | 1976 |
Postoperative treatment with corticosteroids and salazosulphapyridine (Salazopyrin) after radical resection for Crohn's disease.
Topics: Adult; Clinical Trials as Topic; Crohn Disease; Drug Evaluation; Drug Therapy, Combination; Female; | 1976 |
Sulphasalazine in asymptomatic Crohn's disease. A multicentre trial.
Topics: Adolescent; Adult; Clinical Trials as Topic; Crohn Disease; Female; Humans; Male; Middle Aged; Sulfa | 1977 |
[Prevention of recurrence by salazosulfapyridine (azulfidine) therapy in Crohn's disease. A double blind study].
Topics: Clinical Trials as Topic; Colon; Crohn Disease; Double-Blind Method; Humans; Recurrence; Sulfasalazi | 1976 |
The long-term prophylactic effect of salazosulphapyridine (Salazopyrin) in primarily resected patients with Crohn's disease. A controlled double-blind trial.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Crohn Disease; Double-Blind Method; Drug Evaluati | 1978 |
Drug treatment of inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Bacterial Agents; Antidiarrheals; Azathio | 1979 |
[Therapeutic trials in Crohn's disease and ulcerative colitis: ethics, objectives and methodology. A G.R.E.C. cooperative study].
Topics: Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Double-Blind Method; Ethics, Medical; | 1979 |
National Cooperative Crohn's Disease Study: study design and conduct of the study.
Topics: Azathioprine; Clinical Trials as Topic; Crohn Disease; Double-Blind Method; Drug Therapy, Combinatio | 1979 |
National Cooperative Crohn's Disease Study: results of drug treatment.
Topics: Adult; Azathioprine; Clinical Trials as Topic; Crohn Disease; Double-Blind Method; Female; Follow-Up | 1979 |
National Cooperative Crohn's Disease Study: adverse reactions to study drugs.
Topics: Adult; Azathioprine; Blood Cell Count; Clinical Trials as Topic; Crohn Disease; Double-Blind Method; | 1979 |
Azathioprine-related pancreatitis in patients with Crohn's disease.
Topics: Adult; Amylases; Azathioprine; Clinical Trials as Topic; Crohn Disease; Double-Blind Method; Female; | 1979 |
A trial of sulfasalazine as adjunctive therapy in Crohn's disease.
Topics: Adult; Clinical Trials as Topic; Crohn Disease; Double-Blind Method; Drug Therapy, Combination; Fema | 1979 |
Correlations between clinical, blood leukocyte, and skin test data in the National Cooperative Crohn's Disease Study.
Topics: Adult; Azathioprine; Crohn Disease; Female; Granulocytes; Humans; Immunity, Cellular; Intradermal Te | 1979 |
Maintenance of remission in Crohn's disease: is 5'-aminosalicylic acid the answer?
Topics: Aminosalicylic Acids; Crohn Disease; Humans; Mesalamine; Sulfasalazine | 1992 |
Sulphasalazine and prednisone compared with sulphasalazine for treating active Crohn disease. A double-blind, randomized, multicenter trial.
Topics: Adolescent; Adult; Crohn Disease; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ma | 1991 |
Sulfasalazine vs. steroids in Crohn's disease: David vs. Goliath?
Topics: Crohn Disease; Double-Blind Method; Drug Therapy, Combination; Humans; Prednisone; Sulfasalazine | 1991 |
Comparison of enteral nutrition and drug treatment in active Crohn's disease. Results of the European Cooperative Crohn's Disease Study. IV.
Topics: Adult; Crohn Disease; Drug Therapy, Combination; Enteral Nutrition; Female; Food, Formulated; Humans | 1991 |
[New developments in the treatment of inflammatory bowel diseases. What is certain?].
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Humans; Immunosu | 1990 |
Feasibility and effectiveness of a defined-formula diet regimen in treating active Crohn's disease. European Cooperative Crohn's Disease Study III.
Topics: Adult; Crohn Disease; Drug Therapy, Combination; Energy Intake; Female; Food, Formulated; Humans; Ma | 1990 |
Inhibition of cell mediated cytotoxicity by sulphasalazine: effect of in vivo treatment with 5-aminosalicylic acid and sulphasalazine on in vitro natural killer cell activity.
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Cytotoxicity Tests, Immunologic; Cytotoxic | 1990 |
[The Crohn Disease Study Group].
Topics: Adolescent; Adult; Aged; alpha 1-Antitrypsin; Clinical Trials as Topic; Crohn Disease; Defecation; F | 1987 |
Postoperative recurrence of Crohn's disease in relation to radicality of operation and sulfasalazine prophylaxis: a multicenter trial.
Topics: Adolescent; Adult; Aged; Combined Modality Therapy; Crohn Disease; Double-Blind Method; Female; Huma | 1989 |
Clinical relapse of Crohn's disease under standardized conservative treatment and after excisional surgery.
Topics: Adult; Colectomy; Crohn Disease; Female; Follow-Up Studies; Humans; Intestine, Small; Life Tables; M | 1989 |
[Prevention of recurrence of chronic inflammatory bowel diseases].
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Humans; Immunosu | 1989 |
[Successful acute treatment of chronic inflammatory intestinal diseases with oral 5-aminosalicylic acid].
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Female; Humans; M | 1985 |
European Cooperative Crohn's Disease Study (ECCDS): colonoscopy.
Topics: Adult; Clinical Trials as Topic; Colon; Colonoscopy; Crohn Disease; Drug Therapy, Combination; Femal | 1985 |
European Cooperative Crohn's Disease Study (ECCDS): clinical features and natural history.
Topics: Adrenal Cortex Hormones; Adult; Colon; Crohn Disease; Europe; Female; Humans; Ileum; International C | 1985 |
Salazopyrin in the management of Crohn's disease. The Japanese Research Committee for Crohn's disease.
Topics: Adolescent; Adult; Clinical Trials as Topic; Crohn Disease; Drug Combinations; Female; Glucosamine; | 1985 |
HLA-B27 related arthritis and bowel inflammation. Part 1. Sulfasalazine (salazopyrin) in HLA-B27 related reactive arthritis.
Topics: Adolescent; Adult; Arthritis; Child; Clinical Trials as Topic; Colitis, Ulcerative; Colonoscopy; Cro | 1985 |
[Metronidazole in the treatment of Crohn disease. Results of a controlled randomized prospective study].
Topics: Clinical Trials as Topic; Crohn Disease; Follow-Up Studies; Humans; Intestinal Fistula; Metronidazol | 1985 |
Sulfasalazine and new analogues.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Clinical Trials as Topic; Colitis, Ulcerative; C | 1986 |
[Adjuvant therapy with elemental diet in chronic inflammatory intestinal diseases. Comparative study].
Topics: Adolescent; Adult; Blood Proteins; Blood Sedimentation; Colitis, Ulcerative; Combined Modality Thera | 1986 |
Sulphasalazine: a review of 40 years' experience.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Diseas | 1986 |
[Drug therapy of chronic inflammatory intestinal diseases--current status of 5-aminosalicylic acid].
Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Azathioprine; Clinical Trials as Topic; Colitis, Ulce | 1986 |
Mesalazine tolerance in patients with inflammatory bowel disease and previous intolerance or allergy to sulphasalazine or sulphonamides.
Topics: Adolescent; Adult; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Diseas | 1987 |
Oral 5-aminosalicylic acid preparations in treatment of inflammatory bowel disease. An update.
Topics: Administration, Oral; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Dis | 1987 |
[Clinical effect of salazosulfapyridine (salazopyrin) in Crohn's disease. A controlled double-blind investigation].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Crohn Disease; Female; Humans; Male; Middle Aged; | 1974 |
The clinical effect of salazosulphapyridine (Salazopyrin r) in Crohn's disease. A controlled double-blind study.
Topics: Adolescent; Adult; Aged; Blood Sedimentation; Body Weight; Clinical Trials as Topic; Crohn Disease; | 1974 |
Studies of intestinal microflora. V. Fecal microbial ecology in ulcerative colitis and regional enteritis: relationship to severity of disease and chemotherapy.
Topics: Adolescent; Adult; Bacteriological Techniques; Clinical Trials as Topic; Colitis, Ulcerative; Crohn | 1968 |
411 other studies available for sulfasalazine and Colitis, Granulomatous
Article | Year |
---|---|
Thiopurine drugs azathioprine and 6-mercaptopurine inhibit Mycobacterium paratuberculosis growth in vitro.
Topics: Animals; Azathioprine; Bacteriological Techniques; Cattle; Cattle Diseases; Colony Count, Microbial; | 2008 |
Olmesartan medoxomil self-microemulsifying drug delivery system reverses apoptosis and improves cell adhesion in trinitrobenzene sulfonic acid-induced colitis in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cadherins; Caspase 3; Cell Adhesion; Colitis; Crohn | 2022 |
Development of Inflammatory Bowel Disease in Children With Juvenile Idiopathic Arthritis Treated With Biologics.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Colitis, Ulcerative; Crohn Di | 2023 |
Development of Inflammatory Bowel Disease in Children With Juvenile Idiopathic Arthritis Treated With Biologics.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Colitis, Ulcerative; Crohn Di | 2023 |
Development of Inflammatory Bowel Disease in Children With Juvenile Idiopathic Arthritis Treated With Biologics.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Colitis, Ulcerative; Crohn Di | 2023 |
Development of Inflammatory Bowel Disease in Children With Juvenile Idiopathic Arthritis Treated With Biologics.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Colitis, Ulcerative; Crohn Di | 2023 |
Development of Inflammatory Bowel Disease in Children With Juvenile Idiopathic Arthritis Treated With Biologics.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Colitis, Ulcerative; Crohn Di | 2023 |
Development of Inflammatory Bowel Disease in Children With Juvenile Idiopathic Arthritis Treated With Biologics.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Colitis, Ulcerative; Crohn Di | 2023 |
Development of Inflammatory Bowel Disease in Children With Juvenile Idiopathic Arthritis Treated With Biologics.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Colitis, Ulcerative; Crohn Di | 2023 |
Development of Inflammatory Bowel Disease in Children With Juvenile Idiopathic Arthritis Treated With Biologics.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Colitis, Ulcerative; Crohn Di | 2023 |
Development of Inflammatory Bowel Disease in Children With Juvenile Idiopathic Arthritis Treated With Biologics.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Colitis, Ulcerative; Crohn Di | 2023 |
Tofacitinib for the treatment of inflammatory bowel disease-associated arthritis: two case reports.
Topics: Adult; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Female; Humans; Inflammatory Bowel | 2023 |
Benign Evolution of SARS-Cov2 Infections in Children With Inflammatory Bowel Disease: Results From Two International Databases.
Topics: Adolescent; Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Child; Colitis, Ulcerative; Co | 2021 |
A chromatographic approach to development of 5-aminosalicylate/folic acid fixed-dose combinations for treatment of Crohn's disease and ulcerative colitis.
Topics: Chromatography; Colitis, Ulcerative; Crohn Disease; Drug Combinations; Folic Acid; Humans; Inflammat | 2020 |
COVID-19 in IBD: The experience of a single tertiary IBD center.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Biological Products; | 2021 |
The Patterns of Use of Medications for Inflammatory Bowel Disease During Pregnancy in the US and Sweden Are Changing.
Topics: Aminosalicylic Acid; Colitis, Ulcerative; Crohn Disease; Female; Gastrointestinal Agents; Humans; Im | 2021 |
Sulfasalazine-Induced Crystalluria Causing Severe Acute Kidney Injury.
Topics: Acute Kidney Injury; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antiparkinson Agents; Carbidopa; | 2017 |
Stevens-Johnson syndrome on treatment with sulfasalazine for Crohn's disease: Need for a multidisciplinary approach.
Topics: Adult; Crohn Disease; Female; Gastrointestinal Agents; Humans; Medical Illustration; Patient Care Te | 2019 |
An infiltrated vulvar plaque: Metastatic cutaneous Crohn's disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Crohn Disease; Edema; Erythema; Female; Gluco | 2019 |
Canadian Association of Gastroenterology Clinical Practice Guideline for the Management of Luminal Crohn's Disease.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; A | 2019 |
Granulomatous dacryoadenitis in regional enteritis (crohn disease).
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Biomarkers; CD8-Positive T-Lymphocytes | 2014 |
Increasing rate of inflammatory bowel disease: a 12-year retrospective study in NingXia, China.
Topics: Adolescent; Adult; Age Distribution; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; | 2016 |
[Crohn's disease: Vulvar edema and swelling].
Topics: Adrenal Cortex Hormones; Anus Diseases; Crohn Disease; Drug Combinations; Drug Substitution; Edema; | 2016 |
Evaluation of therapeutic effect of low dose naltrexone in experimentally-induced Crohn's disease in rats.
Topics: Animals; Crohn Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Comb | 2016 |
Five-year Safety Data From ENCORE, a European Observational Safety Registry for Adults With Crohn's Disease Treated With Infliximab [Remicade®] or Conventional Therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents; Azathio | 2017 |
Renal effects of long-term treatment with 5-aminosalicylic acid.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcera | 2009 |
Sulphasalazine lung toxicity: report of two cases.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Bronchiectasis; Cough; Crohn Disease; Female; Hu | 2010 |
Dermatofibroma in a patient with Crohn's disease: a novel clinical manifestation.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Drug Therapy, Combination; Female; Gl | 2010 |
Pleuropericardial effusion after 37 years of sulfasalazine therapy.
Topics: Crohn Disease; Drug Administration Schedule; Gastrointestinal Agents; Humans; Male; Middle Aged; Per | 2012 |
Pharmacologic evaluation of sulfasalazine, FTY720, and anti-IL-12/23p40 in a TNBS-induced Crohn's disease model.
Topics: Animals; Antibodies, Monoclonal; Crohn Disease; Diarrhea; Disease Models, Animal; Female; Fingolimod | 2011 |
Metastatic Crohn's disease of the penis: two cases.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Child; Circumcision, Male; Crohn | 2012 |
Uveitis preceding Crohn's disease by 8 years.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Child; Child, Preschool; Crohn Disease; Drug | 2011 |
Birth outcome in women with ulcerative colitis and Crohn's disease, and pharmacoepidemiological aspects of anti-inflammatory drug therapy.
Topics: Adrenal Cortex Hormones; Adult; Aminosalicylic Acid; Anti-Inflammatory Agents; Anti-Inflammatory Age | 2011 |
[Mesalazine and sulphasalazine for Crohn's disease: few indications, severe adverse reactions].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Female; Humans; Lung Diseases, Inters | 2011 |
Has there been a change in the natural history of Crohn's disease? Surgical rates and medical management in a population-based inception cohort from Western Hungary between 1977-2009.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Chi-Square Dis | 2012 |
[Guidelines for the management of Crohn's disease].
Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Budesonide; Crohn | 2012 |
TPMT in the treatment of Crohn's disease with azathioprine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Biomarkers; Crohn Disease; Drug Interactions; | 2002 |
Unilateral retinal vasculitis, branch retinal artery occlusion and subsequent retinal neovascularization in Crohn's disease.
Topics: Adult; Anti-Inflammatory Agents; Crohn Disease; Diagnostic Techniques, Ophthalmological; Drug Combin | 2001 |
Which 5-ASA?
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Enema; Humans; Inflammatory Bowel Diseases | 2002 |
An adolescent with IgA nephropathy and Crohn disease: pathogenetic implications.
Topics: Adolescent; Alkylating Agents; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; A | 2002 |
Clonal marrow abnormalities after azathioprine and sulfasalazine exposure in Crohn's disease: a cautionary tale.
Topics: Adult; Azathioprine; Crohn Disease; Humans; Male; Myelodysplastic Syndromes; Neutrophils; Sulfasalaz | 2002 |
Inflammatory bowel disease in pregnancy.
Topics: Aminosalicylic Acids; Azathioprine; Colitis, Ulcerative; Crohn Disease; Female; Humans; Infertility, | 2003 |
[Crohn's disease in children].
Topics: Child; Crohn Disease; Humans; Mesalamine; Sulfasalazine | 2002 |
Decrease in activity of smooth muscle L-type Ca2+ channels and its reversal by NF-kappaB inhibitors in Crohn's colitis model.
Topics: Animals; Calcium Channels, L-Type; Colitis; Crohn Disease; Electric Conductivity; Enzyme Inhibitors; | 2003 |
Hepatosplenic T-gammadelta lymphoma in a patient with Crohn's disease treated with azathioprine.
Topics: Adrenal Cortex Hormones; Adult; Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; | 2003 |
Regional ileitis (cicatrizing enteritis, Crohn's disease). Some considerations in its medical management and a note on the use of salazopyrine (azopyrin).
Topics: Crohn Disease; Drug Combinations; Glucosamine; Humans; Ileitis; Sulfasalazine | 1950 |
Clinical features and management of Crohn's disease in Chinese patients.
Topics: Adolescent; Adult; Aged; Azathioprine; Biopsy; Child; Crohn Disease; Endoscopy, Gastrointestinal; Fe | 2004 |
Intestinal and extra-intestinal cancer in Crohn's disease: follow-up of a population-based cohort in Copenhagen County, Denmark.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hor | 2004 |
Induction of T lymphocyte apoptosis by sulphasalazine in patients with Crohn's disease.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cells, Cultured; Child; Child | 2004 |
[Chronic inflammatory bowel diseases. Update on evidence-based therapy].
Topics: Administration, Oral; Administration, Rectal; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Ant | 2005 |
The case for using 5-aminosalicyclates in Crohn's disease: pro.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Humans; Mesalamine; Meta-Analysis as Topic; | 2005 |
Penile and scrotal swelling in a child.
Topics: Anti-Infective Agents; Biopsy; Child; Crohn Disease; Genital Diseases, Male; Humans; Lymphedema; Mal | 2005 |
Sinonasal involvement as a rare extraintestinal manifestation of Crohn's disease.
Topics: Acute Disease; Adolescent; Adult; Anti-Infective Agents; Crohn Disease; Diagnosis, Differential; Eth | 2007 |
Treatment with infliximab in a patient with ankylosing spondylitis and Crohn's disease.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antibodies, Monoclonal; Biopsy; Colon; Colonoscop | 2006 |
[A case of salazosulfapyridine-induced pneumonitis presenting with multiple pulmonary nodules and lymphadenopathy].
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Female; Humans; Lymphatic Diseas | 2006 |
[Crohn's disease presenting with recurrent acute polyradiculoneuropathy].
Topics: Adult; Anti-Inflammatory Agents; Budesonide; Combined Modality Therapy; Crohn Disease; Diarrhea; Dru | 2007 |
Therapeutic drug use in women with Crohn's disease and birth outcomes: a Danish nationwide cohort study.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Confidence Intervals; Congenital Abnorma | 2007 |
Granulomatous ileitis in a patient with ankylosing spondylitis.
Topics: Adult; Back Pain; Biopsy; Crohn Disease; Diagnosis, Differential; Gastrointestinal Agents; Humans; I | 2007 |
Saliva: plasma concentration relationships for sulphapyridine following sulphasalazine administration to normal volunteers and patients with inflammatory bowel disease.
Topics: Colitis, Ulcerative; Crohn Disease; Half-Life; Humans; Intestinal Absorption; Kinetics; Male; Phenot | 1980 |
[Ulcerative colitis and Crohn's colitis. Medical or surgical treatment].
Topics: Anti-Inflammatory Agents; Betamethasone; Colectomy; Colitis; Colitis, Ulcerative; Crohn Disease; Hum | 1980 |
Therapy of inflammatory bowel disease, including use of immunosuppressive agents.
Topics: Adrenocorticotropic Hormone; Colitis, Ulcerative; Crohn Disease; Diet; Humans; Immunosuppressive Age | 1980 |
Pulmonary function in patients with inflammatory bowel disease.
Topics: Adolescent; Adult; Aged; Colitis, Ulcerative; Crohn Disease; Female; Humans; Male; Middle Aged; Pulm | 1980 |
Management of Crohn's disease involving the duodenum, including duodenal cutaneous fistula.
Topics: Adult; Crohn Disease; Duodenal Diseases; Female; Humans; Intestinal Fistula; Male; Middle Aged; Pare | 1980 |
Management of Crohn's disease: time for audit?
Topics: Azathioprine; Crohn Disease; Humans; Steroids; Sulfasalazine | 1980 |
Results of operative management of Crohn's disease: A series of 50 patients managed by one surgeon.
Topics: Australia; Crohn Disease; Female; Follow-Up Studies; Humans; Male; Recurrence; Sulfasalazine | 1980 |
[Side effects of salicylazosulfapyridine therapy].
Topics: Agranulocytosis; Colitis, Ulcerative; Crohn Disease; Exanthema; Fever; Humans; Sulfasalazine | 1980 |
Reflections on the treatment of Crohn's disease, the NCCDS report, and on randomized clinical trials.
Topics: Azathioprine; Clinical Trials as Topic; Crohn Disease; Double-Blind Method; Humans; Prednisone; Rand | 1980 |
[Male infertility during treatment with salazosulfapyridine].
Topics: Adult; Crohn Disease; Humans; Infertility, Male; Male; Proctitis; Sulfasalazine | 1980 |
The treatment of Crohn's disease.
Topics: Azathioprine; Bed Rest; Crohn Disease; Drug Therapy, Combination; Humans; Prednisone; Steroids; Sulf | 1980 |
Shortcomings of the National Crohn's Disease Study: the exclusion of azathioprine without adequate trial.
Topics: Azathioprine; Clinical Trials as Topic; Crohn Disease; Double-Blind Method; Drug Synergism; Drug The | 1981 |
Pregnancy in inflammatory bowel disease: effect of sulfasalazine and corticosteroids on fetal outcome.
Topics: Adrenal Cortex Hormones; Colitis, Ulcerative; Crohn Disease; Female; Fetal Death; Fetus; Humans; Inf | 1981 |
Medical therapy of inflammatory bowel disease.
Topics: Acute Disease; Adjuvants, Immunologic; Anus Diseases; Azathioprine; Colitis, Ulcerative; Crohn Disea | 1980 |
[Colitis and drug-induced lupus: the role of salazopyrine].
Topics: Adult; Crohn Disease; Drug Combinations; Female; Glucosamine; Humans; Lupus Erythematosus, Systemic; | 1980 |
[Ulcerative and granulomatous colitis].
Topics: Colitis, Ulcerative; Colonoscopy; Crohn Disease; Diagnosis, Differential; Humans; Prednisolone; Sulf | 1981 |
Azulfidine-induced oligospermia.
Topics: Adult; Crohn Disease; Humans; Ileitis; Male; Oligospermia; Spermatozoa; Sulfasalazine | 1980 |
[Treatment of Crohn's disease with metronidazole (author's transl)].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Crohn Disease; Drug Therapy, Combination; Female; | 1981 |
Sulphasalazine and male infertility: reversibility and possible mechanism.
Topics: Adult; Colitis, Ulcerative; Crohn Disease; Female; Humans; Infertility, Male; Male; Middle Aged; Pre | 1981 |
Incidence of sulphasalazine-induced male infertility.
Topics: Adolescent; Adult; Colitis, Ulcerative; Crohn Disease; Humans; Infertility, Male; Male; Middle Aged; | 1981 |
[Therapy of Crohn disease].
Topics: Adolescent; Adult; Age Factors; Child; Crohn Disease; Female; Glucocorticoids; Humans; Male; Middle | 1981 |
The management of Crohn's disease.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antidiarrheals; Azathioprine; Crohn Disease; Humans; | 1981 |
[An approach to the medical management of inflammatory bowel disease (author's transl)].
Topics: Azathioprine; Colitis; Colitis, Ulcerative; Crohn Disease; Humans; Parenteral Nutrition, Total; Pred | 1981 |
[Evaluation of the results of radical surgical treatment of Crohn disease as related to a diversified postoperative treatment].
Topics: Azathioprine; Crohn Disease; Follow-Up Studies; Humans; Postoperative Care; Postoperative Complicati | 1981 |
[Differentiated therapy in Crohn's disease].
Topics: Adrenocorticotropic Hormone; Crohn Disease; Humans; Ileitis; Peritonitis; Sulfasalazine | 1981 |
Ultrastructure of intestinal lymphatics in Crohn's disease.
Topics: Adult; Aged; Cell Membrane Permeability; Crohn Disease; Female; Humans; Hypobetalipoproteinemias; Il | 1981 |
Simplified high-performance liquid chromatographic method for 5-aminosalicylic acid in plasma and urine.
Topics: Aminosalicylic Acids; Chromatography, High Pressure Liquid; Colitis, Ulcerative; Crohn Disease; Huma | 1981 |
Crohn disease: a hopeful note.
Topics: Crohn Disease; Humans; Mercaptopurine; Prednisone; Sulfasalazine | 1981 |
The effect of metronidazole and sulfasalazine on the fecal flora in patients with Crohn's disease.
Topics: Adolescent; Adult; Bacteroides; Child; Crohn Disease; Escherichia coli; Feces; Female; Humans; Male; | 1981 |
[Crohn disease and ulcerative colitis - current status: internal medicine aspects].
Topics: Adrenal Cortex Hormones; Azathioprine; Colitis, Ulcerative; Crohn Disease; Diagnosis, Differential; | 1981 |
Acetylator phenotype and serum levels of sulfapyridine in patients with inflammatory bowel disease.
Topics: Acetylation; Adolescent; Adult; Aged; Anti-Infective Agents; Colitis; Colitis, Ulcerative; Crohn Dis | 1981 |
Colitis in chronic granulomatous disease.
Topics: Adolescent; Colectomy; Colitis; Crohn Disease; Diagnosis, Differential; Granulomatous Disease, Chron | 1982 |
Increased suppressor cell activity in inflammatory bowel disease.
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Humans; Hydrocortisone; In Vitro Technique | 1981 |
Clinical effect of metronidazole and sulfasalazine on Crohn's disease in relation to changes in the fecal flora.
Topics: Adolescent; Adult; Bacteroides; Bacteroides Infections; Child; Colitis; Crohn Disease; Enteritis; Fe | 1981 |
Placental transfer of sulphasalazine and sulphapyridine and some of its metabolites.
Topics: Colitis; Colitis, Ulcerative; Crohn Disease; Female; Humans; Infant, Newborn; Maternal-Fetal Exchang | 1981 |
Pseudomembranous colitis. A complication of sulfasalazine therapy in a patient with Crohn's colitis.
Topics: Adult; Crohn Disease; Enterocolitis, Pseudomembranous; Female; Humans; Sulfasalazine | 1981 |
[Conservative therapy of Crohn disease].
Topics: Adrenal Cortex Hormones; Azathioprine; Crohn Disease; Humans; Pancreatitis; Psychotherapy; Pyridazin | 1982 |
[Treatment of Crohn's disease].
Topics: Adrenal Cortex Hormones; Azathioprine; Crohn Disease; Humans; Sulfasalazine | 1982 |
Salicylazosulfapyridine and male infertility.
Topics: Adult; Colitis, Ulcerative; Crohn Disease; Humans; Infertility, Male; Male; Semen; Sulfasalazine | 1981 |
Albumin reserve for binding of bilirubin in maternal and cord serum under treatment with sulphasalazine.
Topics: Adult; Albumins; Bilirubin; Colitis, Ulcerative; Crohn Disease; Female; Fetal Blood; Humans; Infant, | 1981 |
The disposition and metabolism of sulphasalazine (salicylazosulphapyridine) in man.
Topics: Adult; Bile; Colitis, Ulcerative; Crohn Disease; Half-Life; Humans; Sulfasalazine; Time Factors | 1982 |
[Salozosulphapyridine and its metabolites in ulcerative colitis and Crohn disease].
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Humans; Sulfasalazine; Suppositories | 1982 |
[Clinical features of inflammatory bowel disease (author's transl)].
Topics: Azathioprine; Bacterial Infections; Crohn Disease; Diarrhea; Drug Combinations; Fluid Therapy; Gluco | 1982 |
[Estimations of the serum levels of sulfapyridine on patients treated with sulfasalazin (author's transl)].
Topics: Adult; Colitis, Ulcerative; Crohn Disease; Female; Humans; Male; Sulfanilamides; Sulfapyridine; Sulf | 1982 |
[5-Aminosalicylic acid in ulcerative colitis and Crohn's disease (author's transl)].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents; Co | 1982 |
Sulphasalazine and spermatogenesis.
Topics: Adolescent; Adult; Colitis, Ulcerative; Crohn Disease; Humans; Male; Middle Aged; Spermatogenesis; S | 1982 |
Diagnosis and medical management of Crohn's disease.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Crohn Disease; Diagnosis, Differential; Diarrhea; Fo | 1982 |
[The treatment of inflammatory diseases of the colon with salazopyrine].
Topics: Colitis; Crohn Disease; Drug Combinations; Glucosamine; Humans; Proctocolitis; Sulfasalazine | 1982 |
Ocular manifestations of inflammatory bowel disease.
Topics: Adult; Aged; Corneal Ulcer; Crohn Disease; Eye Diseases; Female; Humans; Hydrocortisone; Inflammatio | 1982 |
Defective lymphocyte IgA production in inflammatory bowel disease.
Topics: Adolescent; Adult; Antibody-Producing Cells; Child; Colitis, Ulcerative; Crohn Disease; Female; Huma | 1982 |
Pregnancy and inflammatory bowel disease.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adrenal Cortex Hormones; Colitis, Ulcerative; Cr | 1982 |
Sulfasalazine-induced lupus syndrome in a patient with Crohn's disease.
Topics: Adolescent; Antibodies, Antinuclear; Crohn Disease; Female; Humans; Lupus Erythematosus, Systemic; S | 1982 |
Functional suppressor T cell activity in Crohn's disease and the effects of sulphasalazine.
Topics: Aminosalicylic Acids; Concanavalin A; Crohn Disease; Humans; Lymphocyte Activation; Mesalamine; Sulf | 1982 |
Will there be a next generation of sulfasalazine?
Topics: Administration, Oral; Aminosalicylic Acids; Animals; Colitis, Ulcerative; Crohn Disease; Delayed-Act | 1982 |
Anti-inflammatory drug treatment of Crohn's disease: a prospective evaluation of 100 consecutively treated patients.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Crohn Disease; Drug Therapy, Combination; Female; Hum | 1980 |
Compliance to therapy in patients on a maintenance dose of sulfasalazine.
Topics: Colitis, Ulcerative; Crohn Disease; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Pat | 1982 |
[(Quality of semen in patients with Crohn's disease) ].
Topics: Adult; Crohn Disease; Humans; Male; Middle Aged; Semen; Sperm Count; Sperm Motility; Spermatogenesis | 1982 |
Desensitization of patients with inflammatory bowel disease to sulfasalazine.
Topics: Colitis, Ulcerative; Crohn Disease; Desensitization, Immunologic; Dose-Response Relationship, Drug; | 1982 |
[Ulcerative colitis and Crohn disease].
Topics: Child; Colitis, Ulcerative; Crohn Disease; Humans; Sulfasalazine | 1982 |
Sulfasalazine intolerance. A retrospective survey of the reasons for discontinuing treatment with sulfasalazine in patients with chronic inflammatory bowel disease.
Topics: Colitis, Ulcerative; Crohn Disease; Diarrhea; Drug Tolerance; Dyspepsia; Exanthema; Fever; Humans; R | 1982 |
Inflammatory bowel disease.
Topics: Azathioprine; Colitis, Ulcerative; Colonoscopy; Crohn Disease; Drug Combinations; Glucosamine; Human | 1982 |
Costs of sulfasalazine and metronidazole.
Topics: Crohn Disease; Humans; Metronidazole; Prescription Fees; Sulfasalazine | 1983 |
[40 years of salazosulfapyridine. Is end in sight?].
Topics: Colitis, Ulcerative; Crohn Disease; Drug Hypersensitivity; Humans; Intestinal Absorption; Sulfasalaz | 1982 |
Retrograde colonic spread of sulphasalazine enemas.
Topics: Adult; Aged; Animals; Colitis, Ulcerative; Crohn Disease; Enema; Female; Humans; Male; Middle Aged; | 1982 |
Immunopathology of ulcerative colitis and Crohn's disease, nonsurgical therapeutic considerations.
Topics: Acute Disease; Antibody Formation; Child; Colitis, Ulcerative; Crohn Disease; Glucocorticoids; Human | 1982 |
[Treatment of Crohn disease in childhood].
Topics: Adolescent; Azathioprine; Child; Child Development; Colectomy; Crohn Disease; Dose-Response Relation | 1982 |
Is plasma level monitoring of sulfasalazine indicated in the treatment of Crohn's disease or ulcerative colitis?
Topics: Adolescent; Adult; Child; Colitis, Ulcerative; Crohn Disease; Drug Evaluation; Humans; Kinetics; Sul | 1980 |
Nine years of diarrhea and abdominal pain.
Topics: Aged; Crohn Disease; Diarrhea; Duodenal Diseases; Female; Humans; Joint Diseases; Pain; Prednisone; | 1983 |
[Recurrence of Crohn disease--a surgical and interdisciplinary problem].
Topics: Adult; Colectomy; Crohn Disease; Female; Humans; Male; Patient Care Team; Postoperative Care; Progno | 1983 |
Bacterial L-form isolation from inflammatory bowel disease patients.
Topics: Biopsy; Colitis, Ulcerative; Colon; Crohn Disease; Culture Media; Feces; Humans; Intestinal Mucosa; | 1983 |
[Sugar-free diet as long-term or interval treatment in the remission phase of Crohn disease--a prospective study].
Topics: Adult; Colectomy; Crohn Disease; Dietary Carbohydrates; Dietary Fiber; Female; Food, Formulated; Hum | 1982 |
Clostridium difficile and inflammatory bowel disease.
Topics: Anti-Bacterial Agents; Bacterial Toxins; Clostridium; Colitis, Ulcerative; Crohn Disease; Diarrhea; | 1983 |
Drug management of inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Bacterial Agents; Antidiarrheals; Azathio | 1983 |
Folate deficiency in operated terminal ileitis (Crohn's disease).
Topics: Adolescent; Adult; Aged; Crohn Disease; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Hum | 1983 |
The use of sulfasalazine in the treatment of inflammatory bowel disease.
Topics: Colitis, Ulcerative; Crohn Disease; Humans; Sulfasalazine | 1983 |
Sulfasalazine pneumonitis.
Topics: Adult; Cough; Crohn Disease; Dyspnea; Eosinophilia; Fever; Humans; Male; Pneumonia; Radiography; Sul | 1983 |
Prolonged constant rate elemental enteral nutrition in Crohn's disease.
Topics: Adolescent; Body Height; Body Weight; Cecum; Child; Crohn Disease; Enteral Nutrition; Female; Food, | 1982 |
Semen and sulphasalazine.
Topics: Colitis, Ulcerative; Crohn Disease; Humans; Infertility, Male; Male; Semen; Sulfasalazine | 1982 |
Pharmacotherapy of inflammatory bowel disease. Part 2. Metronidazole.
Topics: Crohn Disease; Humans; Metronidazole; Perineum; Sulfasalazine | 1983 |
Pharmacotherapy of inflammatory bowel disease. Part 1. Sulfasalazine.
Topics: Aminosalicylic Acids; Bacteria; Colitis, Ulcerative; Colon; Crohn Disease; Humans; Kinetics; Mesalam | 1983 |
Current status of medical treatment for inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Azathioprine; Colitis, Ulcerative; Crohn Disease; Humans; Mercaptopurine; M | 1983 |
Crohn's disease and pregnancy.
Topics: Abortion, Spontaneous; Adrenal Cortex Hormones; Adult; Crohn Disease; Female; Fertility; Humans; Pre | 1984 |
Medical and surgical treatment of inflammatory bowel disease in pregnancy.
Topics: Adrenocorticotropic Hormone; Antidiarrheals; Colectomy; Colitis, Ulcerative; Crohn Disease; Diet; Fe | 1983 |
[Immunomodulation treatment of inflammatory bowel disease].
Topics: Anti-Bacterial Agents; Antibody Formation; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Co | 1984 |
Desensitization for sulfasalazine skin rash.
Topics: Acetylation; Colitis, Ulcerative; Crohn Disease; Desensitization, Immunologic; Drug Eruptions; Human | 1984 |
Response to drug therapy in Crohn's disease: evaluation by rectal biopsy and mucosal cell counts.
Topics: Biopsy; Cell Count; Crohn Disease; Drug Therapy, Combination; Evaluation Studies as Topic; Humans; I | 1984 |
Impaired semen quality in Crohn's disease--drugs, ill health, or undernutrition?
Topics: Adult; Azathioprine; Crohn Disease; Humans; Male; Middle Aged; Nutrition Disorders; Oligospermia; Pr | 1983 |
Occurrence of Clostridium difficile toxin in inflammatory bowel disease.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Clostridium; Clostridium Infections; Colitis, Ulcera | 1983 |
Selected individual therapeutic problems in inflammatory bowel disease.
Topics: Adult; Azathioprine; Campylobacter Infections; Clostridium Infections; Colectomy; Colitis, Ulcerativ | 1984 |
Circulating lipid A antibodies despite absence of systemic endotoxemia in patients with Crohn's disease.
Topics: Adolescent; Adult; Aged; Antibodies, Bacterial; Colitis, Ulcerative; Crohn Disease; Drug Therapy, Co | 1984 |
The influence of inflammatory bowel disease and its treatment on pregnancy and fetal outcome.
Topics: Abortion, Spontaneous; Colitis, Ulcerative; Congenital Abnormalities; Crohn Disease; Female; Fetal D | 1984 |
Sulfasalazine: adverse effects.
Topics: Adolescent; Crohn Disease; Drug Hypersensitivity; Female; Hemiplegia; Humans; Sulfasalazine | 1984 |
[Crohn disease: when conservative, when surgical treatment?].
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Azathioprine; Colon; Crohn Disease; Dietary Carbohyd | 1984 |
[Crohn's disease. Has there been progress in its treatment?].
Topics: Crohn Disease; Drug Combinations; Female; Glucocorticoids; Glucosamine; Humans; Intestinal Obstructi | 1984 |
Pyoderma gangrenosum at the parastomal site in patients with Crohn's disease.
Topics: Adult; Crohn Disease; Female; Humans; Ileostomy; Middle Aged; Parenteral Nutrition, Total; Postopera | 1984 |
Granulomatous arthritis in Crohn's disease.
Topics: Adolescent; Arthritis; Crohn Disease; Female; Granuloma; Humans; Prednisone; Sulfasalazine; Synovial | 1984 |
Reversible male infertility due to sulphasalazine: studies in man and rat.
Topics: Adult; Aminosalicylic Acids; Animals; Colitis, Ulcerative; Crohn Disease; Dose-Response Relationship | 1984 |
Is tube feeding with elemental diets a primary therapy of Crohn's disease?
Topics: Combined Modality Therapy; Crohn Disease; Enteral Nutrition; Food, Formulated; Humans; Prednisolone; | 1984 |
[Methods for studying inflammatory diseases of the intestine].
Topics: Antibody Formation; Blood Protein Electrophoresis; Colitis; Crohn Disease; Drug Combinations; Glucos | 1984 |
Gastric retention of enteric-coated sulfasalazine tablets. A complication of gastroduodenal Crohn's disease.
Topics: Adult; Crohn Disease; Duodenal Diseases; Female; Humans; Intestinal Obstruction; Stomach Diseases; S | 1984 |
[Crohn disease: I. Possibilities and limits of conservative therapy].
Topics: Aminosalicylic Acids; Combined Modality Therapy; Crohn Disease; Drug Therapy, Combination; Food, For | 1984 |
[Chronic inflammatory intestinal disease and pregnancy].
Topics: Colitis, Ulcerative; Crohn Disease; Female; Glucocorticoids; Humans; Pregnancy; Pregnancy Complicati | 1984 |
[Extent of drug compliance in Crohn disease patients--study of a special ambulatory care unit of a university clinic].
Topics: Adult; Ambulatory Care; Biotransformation; Crohn Disease; Female; Germany, West; Humans; Male; Patie | 1984 |
[Autoantibodies against the exocrine pancreas and against intestinal goblet cells in the diagnosis of Crohn's disease and ulcerative colitis].
Topics: Adolescent; Adult; Aged; Autoantibodies; Colitis, Ulcerative; Complement Fixation Tests; Crohn Disea | 1984 |
[Determination of sulfapyridine levels in serum--a possibility for the control of dose related therapy with sulfasalazine].
Topics: Adult; Colectomy; Colitis, Ulcerative; Crohn Disease; Dose-Response Relationship, Drug; Female; Huma | 1984 |
[Erythema nodosum and Crohn's disease].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Colitis, Ulcerative; Crohn Disease; Diagnosis, Dif | 1984 |
Sulfasalazine metabolite pharmacokinetics in pediatric patients with inflammatory bowel disease: effects of disease activity, acetylator phenotype, and age.
Topics: Acetylation; Adolescent; Adult; Age Factors; Child; Colitis, Ulcerative; Crohn Disease; Dose-Respons | 1982 |
Pseudotumor of the orbit and Crohn's disease.
Topics: Adult; Crohn Disease; Drug Combinations; Female; Fibroma; Glucosamine; Humans; Ileitis; Orbital Neop | 1984 |
[Possible mechanism of action of Azulfidine/Salazopyrin].
Topics: Bacteria; Colitis, Ulcerative; Crohn Disease; Enzymes; Humans; Immunosuppression Therapy; Intestinal | 1981 |
[Azulfidine/Salazopyrin therapy during pregnancy].
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Colitis, Ulcerative; Crohn Disease; Female; Humans; I | 1981 |
[Pharmacokinetics of Azulfidine/Salazopyrin in healthy humans and in patients with chronic inflammatory bowel diseases].
Topics: Colitis, Ulcerative; Crohn Disease; Humans; Intestinal Absorption; Sulfasalazine | 1981 |
[Therapy of chronic inflammatory bowel diseases].
Topics: Acute Disease; Azathioprine; Colitis, Ulcerative; Crohn Disease; Humans; Mercaptopurine; Methylpredn | 1983 |
[Therapy of Crohn's disease].
Topics: Combined Modality Therapy; Crohn Disease; Food, Formulated; Humans; Immunosuppressive Agents; Metron | 1984 |
Up-regulation of E-selectin and intercellular adhesion molecule-1 differs between Crohn's disease and ulcerative colitis.
Topics: Adult; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion Molecules; Cells | 1995 |
Overwhelming varicella pneumonia in a patient with Crohn's disease treated with 6-mercaptopurine.
Topics: Adolescent; Chickenpox; Crohn Disease; Fatal Outcome; Humans; Immunosuppression Therapy; Male; Merca | 1995 |
Side effects of sulphasalazine in patients with rheumatic diseases or inflammatory bowel disease.
Topics: Adult; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Female; Humans; Male; Spondylitis, | 1994 |
[Current therapeutic possibilities in chronic inflammatory intestinal diseases].
Topics: Aminosalicylic Acids; Chronic Disease; Colitis; Colitis, Ulcerative; Crohn Disease; Drug Therapy, Co | 1995 |
Subconjunctival nodules: an unusual ocular complication of Crohn's disease.
Topics: Adult; Conjunctiva; Conjunctival Diseases; Crohn Disease; Glucocorticoids; Humans; Male; Scleritis; | 1994 |
Sulfasalazine, 5-ASA and acute pancreatitis in crohn's disease.
Topics: Acute Disease; Adult; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; | 1994 |
[The role of conservative surgery in Crohn disease: practical results obtained from a case].
Topics: Adult; Colectomy; Crohn Disease; Drug Combinations; Glucosamine; Granuloma; Humans; Ileostomy; Ileum | 1993 |
[Is preventive drug therapy of recurrent Crohn disease indicated after ileocecal resection?].
Topics: Aminosalicylic Acids; Cecum; Combined Modality Therapy; Crohn Disease; Humans; Ileum; Mesalamine; Re | 1994 |
Does aggressive medical therapy for acute ulcerative colitis result in a higher incidence of staged colectomy?
Topics: Acute Disease; Adolescent; Adult; Colectomy; Colitis, Ulcerative; Crohn Disease; Female; Glucocortic | 1994 |
Is maintenance therapy effective in Crohn's disease?
Topics: Aminosalicylic Acids; Crohn Disease; Humans; Mesalamine; Meta-Analysis as Topic; Prednisone; Recurre | 1994 |
Recurrence of Crohn's disease in the neoterminal ileum after ileal resection: is prevention therapy possible?
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Crohn Disease; Humans; Ileitis; Mesalamine; Recurren | 1994 |
Low prevalence of Helicobacter pylori in inflammatory bowel disease: association with sulphasalazine.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Bacterial; Breath Tests; Colitis, Ulcerative; Crohn Dise | 1994 |
Urinary growth hormone in growth-impaired children with chronic inflammatory bowel disease.
Topics: Adolescent; Aminosalicylic Acids; Child; Colitis, Ulcerative; Creatinine; Crohn Disease; Enzyme-Link | 1993 |
[Granulomatous colitis (Crohn disease) in the first year of life].
Topics: Colitis; Colon; Colonoscopy; Crohn Disease; Fiber Optic Technology; Humans; Infant; Male; Radiograph | 1993 |
Disseminated metastatic cutaneous Crohn's disease.
Topics: Adolescent; Crohn Disease; Humans; Male; Prednisolone; Skin; Skin Diseases; Sulfasalazine | 1993 |
Antibodies to human recombinant lipocortin-I in inflammatory bowel disease.
Topics: Adult; Aged; Aged, 80 and over; Annexin A1; Antibody Specificity; Autoantibodies; Bacterial Infectio | 1993 |
Crohn's disease associated with pancreatitis of unknown etiology: a case report.
Topics: Acute Disease; Adult; Crohn Disease; Humans; Male; Metronidazole; Pancreatitis; Parenteral Nutrition | 1993 |
Sulfasalazine-associated encephalopathy in a patient with Crohn's disease.
Topics: Acute Disease; Adult; Brain; Brain Diseases; Chemical and Drug Induced Liver Injury; Coma; Crohn Dis | 1993 |
Sulfasalazine-associated encephalopathy in a patient with Crohn's disease.
Topics: Adult; Brain Diseases; Chemical and Drug Induced Liver Injury; Crohn Disease; Drug Eruptions; Drug H | 1993 |
Maintenance strategies in Crohn's disease.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Combined Modalit | 1996 |
Leukaemia risk in Crohn's disease.
Topics: Adrenal Cortex Hormones; Adult; Colectomy; Combined Modality Therapy; Crohn Disease; Humans; Immunos | 1996 |
Antibodies in patients with inflammatory bowel disease and the apparent influence of medications.
Topics: Adult; Aged; Animals; Antigens, Bacterial; Caseins; Colitis, Ulcerative; Crohn Disease; Food; Gliadi | 1995 |
Crohn's disease and ulcerative colitis with onset in the same year in two sisters.
Topics: Adolescent; Adrenal Cortex Hormones; Azathioprine; Child; Colitis, Ulcerative; Colonoscopy; Crohn Di | 1996 |
Holoprosencephaly in a fetus with maternal medication of sulfasalazine in early gestation. A case report.
Topics: Abnormalities, Drug-Induced; Adult; Anti-Inflammatory Agents; Crohn Disease; Fatal Outcome; Female; | 1996 |
Anticardiolipin antibodies in Crohn's disease associated with diabetes mellitus.
Topics: Anti-Inflammatory Agents; Antibodies, Anticardiolipin; Blood Glucose; Colitis; Crohn Disease; Diabet | 1996 |
[Hypersensitivity to 5-aminosalicylic acid. Value of desensitization by oral route].
Topics: Administration, Oral; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Child; Crohn Di | 1997 |
[Current medical therapies for Crohn's disease in Japan].
Topics: Aminosalicylic Acids; Crohn Disease; Food, Fortified; Gastrointestinal Agents; Humans; Japan; Mesala | 1997 |
Prevalence of Helicobacter pylori infection and related upper gastrointestinal lesions in patients with inflammatory bowel diseases. A cross-sectional study with matching.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Colitis, Ulcerative; Crohn Disease; Cross-Sectional | 1997 |
Isolation and evaluation of susceptibility to sulphasalazine of Desulfovibrio desulfuricans strains from the human digestive tract.
Topics: Adenoma; Adult; Anti-Bacterial Agents; Bacteriological Techniques; Biopsy; Colon; Colonic Diseases, | 1997 |
Sulfasalazine-induced fulminant hepatitis in pediatric Crohn's disease: report of two cases.
Topics: Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Child; Crohn Disease; Female; Huma | 1998 |
[Recurrence-preventive (remission preserving) therapy of chronic inflammatory bowel diseases].
Topics: Anti-Inflammatory Agents; Antimetabolites; Azathioprine; Chronic Disease; Colitis, Ulcerative; Crohn | 1998 |
[Crohn's disease in monozygotic twins].
Topics: Adult; Anti-Inflammatory Agents; Crohn Disease; Diseases in Twins; Gastrointestinal Agents; Humans; | 1998 |
[Vulvar Crohn disease: 3 cases].
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Crohn Disease; Female; Humans; Mesalamine; Middle Aged; | 1997 |
Metastatic Crohn's disease of the lung.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Bronchi; Bron | 1998 |
Esophageal Crohn's disease with esophagopleural fistula.
Topics: Aged; Anti-Infective Agents; Crohn Disease; Drug Therapy, Combination; Endoscopy, Digestive System; | 1998 |
[Inflammatory bowel disease and pregnancy: clinical study of mutual influence, clinical course and treatment].
Topics: Adrenal Cortex Hormones; Adult; Colitis, Ulcerative; Crohn Disease; Female; Gastrointestinal Agents; | 1999 |
[Fulminant hepatitis in two children treated with sulfasalazine for Crohn disease].
Topics: Child; Crohn Disease; Female; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Liver Transpl | 1999 |
Crohn's disease mimicking enterocolitis in a patient with an endorectal pull-through for Hirschsprung's disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Colonoscopy; Crohn Disease; Diagnosis, Differential; | 1999 |
Hyperbaric oxygen as adjunct therapy for Crohn's intractable enteric ulcer.
Topics: Adolescent; Anti-Inflammatory Agents; Colonic Diseases; Crohn Disease; Female; Follow-Up Studies; Fo | 1999 |
Crohn's disease of the esophagus: report of a case.
Topics: Adult; Anti-Inflammatory Agents; Crohn Disease; Esophageal Diseases; Gastrointestinal Agents; Humans | 2000 |
[Association of asymptomatic celiac disease and Crohn's disease].
Topics: Adult; Antibodies; Biopsy; Celiac Disease; Crohn Disease; Female; Gastrointestinal Agents; Gliadin; | 2000 |
[Crohn's disease with the onset resembling systemic lupus erythematosus].
Topics: Administration, Oral; Adult; Crohn Disease; Diagnosis, Differential; Drug Therapy, Combination; Huma | 1999 |
[Therapy of chronic inflammatory intestinal disease].
Topics: Acute Disease; Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Budesonide; Chronic D | 2000 |
Uncommon arthritis as presenting manifestation of silent Crohn's disease.
Topics: Adult; Arthritis; Crohn Disease; Disease Progression; Female; Humans; Prednisone; Sulfasalazine; Tre | 2000 |
[Helicobacter pylori and nonspecific intestinal inflammation].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Bacterial; Colitis, Ul | 2000 |
Is it Crohn's disease? A severe systemic granulomatous reaction to sulfasalazine in patient with rheumatoid arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Crohn Di | 2001 |
[A study of 5-ASA use among young patients with Crohn disease. Regular drug revision is of significance for all children with chronic disease].
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Child; Crohn Disease; Dose-Respons | 2001 |
Down syndrome and Crohn's disease: an extremely rare association.
Topics: Child; Crohn Disease; Down Syndrome; Female; Humans; Intestinal Fistula; Radiography; Sulfasalazine; | 2001 |
[Erythropoietin and hip surgery in an anemic Jehovah's Witness with ankylosing spondylitis, chronic liver disease, and Crohn's disease].
Topics: Anemia, Hypochromic; Antirheumatic Agents; Autoimmune Diseases; Blood Loss, Surgical; Christianity; | 2002 |
[Pancreatic involvement in inflammatory bowel diseases in children].
Topics: Adolescent; Amylases; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Child; Colitis, Ulcerat | 2002 |
The alternate complement pathway in inflammatory bowel disease. Quantitation of the C3 proactivator (factor B) protein.
Topics: Blood Proteins; Colectomy; Colitis, Ulcerative; Complement C3; Complement C4; Complement System Prot | 1976 |
Folic acid absorption in regional enteritis.
Topics: Adult; Carotenoids; Crohn Disease; Feces; Folic Acid; Humans; Intestinal Absorption; Intestines; Int | 1976 |
[Patient with abdominal pain].
Topics: Adult; Ampicillin; Azathioprine; Crohn Disease; Humans; Male; Parenteral Nutrition; Prednisone; Sulf | 1976 |
[Morbus Crohn (enteritis regionalis)].
Topics: Adult; Age Factors; Crohn Disease; Diagnosis, Differential; Drug Therapy, Combination; Female; Human | 1975 |
Crohn's disease of the distal large bowel.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Bacterial Agents; Azathioprine; Colon, Sigmoid; Crohn Dis | 1976 |
[Inflammatory intestinal diseases: ulcerative colitis and Crohn's disease. Early diagnosis and treatment].
Topics: Adrenal Cortex Hormones; Azathioprine; Colitis, Ulcerative; Crohn Disease; Endoscopy; Humans; Sulfas | 1976 |
Pharmacotherapy of inflammatory bowel disease.
Topics: Azathioprine; Colitis, Ulcerative; Crohn Disease; Humans; Hydrocortisone; Sulfasalazine | 1976 |
Anti-inflammatory drug treatment in Crohn's disease.
Topics: Anti-Inflammatory Agents; Azathioprine; Colonic Diseases; Crohn Disease; Female; Humans; Intestinal | 1976 |
[Inflammatory diseases of the colon and salazopyrine. Value of long term treatment].
Topics: Chemical Phenomena; Chemistry; Colitis; Colonic Diseases; Crohn Disease; Female; Gastrointestinal He | 1976 |
Basal and stimulated serum growth hormone concentrations in inflammatory bowel disease.
Topics: Adolescent; Animals; Body Height; Body Weight; Child; Colitis, Ulcerative; Crohn Disease; Female; Gl | 1977 |
Medical management of Crohn's disease in adolescence.
Topics: Adolescent; Child; Crohn Disease; Drug Therapy, Combination; Female; Humans; Male; Prednisone; Sulfa | 1977 |
Inflammatory bowel diseases 1977.
Topics: Azathioprine; Colitis, Ulcerative; Crohn Disease; Cromolyn Sodium; Diet; Eye Diseases; Humans; Joint | 1977 |
Chronic inflammatory bowel disease.
Topics: Adolescent; Adult; Azathioprine; Bile Acids and Salts; Child; Cholestyramine Resin; Colitis, Ulcerat | 1977 |
[Management and prognosis of Crohn's disease].
Topics: Adolescent; Adult; Azathioprine; Crohn Disease; Female; Humans; Male; Prednisolone; Prognosis; Sulfa | 1977 |
Enteritis and the continent ileostomy.
Topics: Crohn Disease; Enteritis; Female; Humans; Ileostomy; Male; Sulfasalazine | 1977 |
Crohn's disease involving the colon: an audit of clinical management.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aged; Azathioprine; Child; | 1977 |
[Macrocheilia and morbus Crohn (author's transl)].
Topics: Adult; Cheilitis; Crohn Disease; Female; Humans; Male; Middle Aged; Sulfasalazine; Triamcinolone | 1977 |
[Chronic-inflammatory intestinal diseases. Clinical picture, complications, differential diagnosis and nonsurgical therapy].
Topics: Adrenal Cortex Hormones; Azathioprine; Chronic Disease; Colitis, Ulcerative; Crohn Disease; Diagnosi | 1977 |
[Crohn's regional enteritis. Clinical report].
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Child; Child, Preschool; Crohn Di | 1977 |
Granulomatous ileocolitis (Crohn's disease).
Topics: Adrenal Cortex Hormones; Crohn Disease; Diagnosis, Differential; Humans; Immunosuppressive Agents; P | 1978 |
Prognosis in children with Crohn's disease.
Topics: Adolescent; Adult; Body Height; Body Weight; Child; Child, Preschool; Colitis; Crohn Disease; Female | 1978 |
Little people, big people, and Crohn's disease.
Topics: Adrenocorticotropic Hormone; Child; Child, Preschool; Crohn Disease; Humans; Hydrocortisone; Prednis | 1978 |
[Current possibilities of treatment of nonspecific ulcerative colitis and Crohn's disease].
Topics: Blood Transfusion; Colitis, Ulcerative; Crohn Disease; Drug Therapy, Combination; Humans; Hydrocorti | 1978 |
Sulfasalazine toxic reactions. Hepatitis, fever, and skin rash with hypocomplementemia and immune complexes.
Topics: Adult; Antigen-Antibody Complex; Chemical and Drug Induced Liver Injury; Complement System Proteins; | 1978 |
The pediatric corner: the varied manifestations of Crohn's disease in children and adolescents.
Topics: Adolescent; Age Factors; Azathioprine; Child; Child, Preschool; Crohn Disease; Female; Hematocrit; H | 1978 |
Granulomatous ileocolitis preceded by three years of pauciarticular arthritis.
Topics: Arthritis, Juvenile; Aspirin; Child; Crohn Disease; Granuloma; Humans; Male; Prednisone; Sulfasalazi | 1978 |
[Crohn's disease: course and prognosis in 169 patients (author's transl)].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Body Weight; Child; Child, Preschool; | 1978 |
Chronic inflammatory bowel disease in children and adolescents: part II.
Topics: Adolescent; Adrenal Cortex Hormones; Child; Chronic Disease; Colitis, Ulcerative; Crohn Disease; Dia | 1978 |
Hemolytic anemia in patients receiving sulfasalazine.
Topics: Anemia, Hemolytic; Colitis, Ulcerative; Crohn Disease; Electrophoresis, Starch Gel; Heinz Bodies; He | 1978 |
Hemolysis during salicylazosulfapyridine therapy.
Topics: Adolescent; Adult; Aged; Anemia, Hemolytic; Colitis, Ulcerative; Crohn Disease; Female; Hemolysis; H | 1978 |
Crohn's disease of the colon.
Topics: Adrenal Cortex Hormones; Adult; Aminosalicylic Acids; Azathioprine; Colectomy; Colitis, Ulcerative; | 1979 |
Pulmonary function in inflammatory bowel disease.
Topics: Adult; Colitis, Ulcerative; Crohn Disease; Female; Humans; Male; Respiration; Respiratory Function T | 1978 |
Small bowel absorption of sulfasalazine and its hepatic metabolism in human beings, cats, and rats.
Topics: Animals; Bile; Cats; Crohn Disease; Humans; Ileostomy; Intestinal Absorption; Liver; Male; Oxidoredu | 1979 |
[Immunosuppressive drugs in intestinal diseases (author's transl)].
Topics: Acute Disease; Adrenal Cortex Hormones; Azathioprine; Colitis, Ulcerative; Crohn Disease; Humans; Im | 1979 |
[Reflections on ten years' experience in the treatment of hemorrhagic colorectitis and Crohn's disease (author's transl)].
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Colitis, Ulcerative; Cro | 1978 |
Radiographic findings of the National Cooperative Crohn's Disease Study.
Topics: Adult; Age Factors; Azathioprine; Colon; Crohn Disease; Duodenum; Female; Humans; Ileum; Intestinal | 1979 |
Sulfapyridine metabolites in children with inflammatory bowel disease receiving sulfasalazine.
Topics: Acetylation; Adolescent; Child; Child, Preschool; Colitis, Ulcerative; Crohn Disease; Female; Humans | 1979 |
Inflammatory bowel disease. Part II.
Topics: Azathioprine; Colitis, Ulcerative; Crohn Disease; Double-Blind Method; Evaluation Studies as Topic; | 1978 |
Folate deficiency in chronic inflammatory bowel diseases.
Topics: Bone Marrow; Bone Marrow Cells; Colitis, Ulcerative; Crohn Disease; Erythrocyte Aging; Erythrocytes; | 1979 |
Sulphasalazine treatment during breast feeding.
Topics: Colitis, Ulcerative; Crohn Disease; Female; Humans; Lactation; Milk, Human; Pregnancy; Sulfapyridine | 1979 |
[Use of a chronomulticorticoid in the treatment of Crohn's disease].
Topics: Adolescent; Adult; Cortisone; Crohn Disease; Drug Therapy, Combination; Female; Humans; Male; Middle | 1979 |
Metronidazole for Crohn's disease.
Topics: Adult; Child; Crohn Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hu | 1975 |
How district hospitals see acute colitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Colectomy; Colitis, Ulcerative; Crohn Disease; Female | 1979 |
[Letter: Crohn's disease].
Topics: Adrenal Cortex Hormones; Azathioprine; Crohn Disease; Diet; Humans; Prednisone; Sulfasalazine | 1975 |
Mucosal-cell counts in ulcerative and granulomatous colitis.
Topics: Biopsy; Cell Count; Colitis, Ulcerative; Connective Tissue; Connective Tissue Cells; Crohn Disease; | 1975 |
Editorial: Sulphasalazine for Crohn's diseases?
Topics: Child; Crohn Disease; Female; Humans; Middle Aged; Pregnancy; Sulfasalazine | 1975 |
Crohn's colitis comes of age.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Colectomy; Colitis, Ulcerative; Colon; Crohn D | 1975 |
Letter: Value of uncontrolled trials in use of sulfasalazine.
Topics: Colitis, Ulcerative; Crohn Disease; Drug Evaluation; Humans; Research Design; Sulfasalazine | 1975 |
Acetylation polymorphism of sulfapyridine in patients with ulcerative colitis and Crohn's disease.
Topics: Acetylation; Adolescent; Adult; Aged; Colitis, Ulcerative; Crohn Disease; Female; Humans; Kinetics; | 1975 |
Sulfasalazine-induced pulmonary disease.
Topics: Acute Disease; Aged; Arthritis, Rheumatoid; Crohn Disease; Female; Humans; Male; Pulmonary Fibrosis; | 1992 |
Is Asacol as effective as sulphasalazine in maintaining remission of Crohn's disease and ulcerative colitis?
Topics: Acrylic Resins; Adolescent; Adult; Aged; Aged, 80 and over; Aminosalicylic Acids; Colitis, Ulcerativ | 1992 |
[Acral vasospasm in Crohn's disease].
Topics: Adult; Blood Flow Velocity; Capillaries; Crohn Disease; Female; Hand; Humans; Male; Microscopy; Midd | 1992 |
[Heparin-induced thrombosis-thrombocytopenia syndrome in Crohn disease. Further thromboses with oral anticoagulation after discontinuation of heparin].
Topics: Administration, Oral; Blood Coagulation Tests; Crohn Disease; Drug Therapy, Combination; Female; Hep | 1992 |
[Aminosalicylates in chronic inflammatory intestinal diseases and rheumatoid arthritis].
Topics: Aminosalicylic Acids; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Humans; Mesalamine; | 1992 |
Cytokines and platelet-activating factor in human inflamed colonic mucosa.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Anti-Idiotypic; Calcimyci | 1992 |
[Clinical study on Crohn disease].
Topics: Antibody-Dependent Cell Cytotoxicity; Crohn Disease; Cytokines; Drug Combinations; Glucosamine; Huma | 1992 |
[Serum cholinesterases as activity parameters in chronic inflammatory bowel diseases].
Topics: Acute-Phase Proteins; Adolescent; Adult; Aged; Aminosalicylic Acids; Child; Cholinesterases; Colitis | 1992 |
Alternate-day prednisone treatment and treatment maintenance in Crohn's disease.
Topics: Adolescent; Adult; Aged; Confidence Intervals; Crohn Disease; Drug Administration Schedule; Drug The | 1991 |
6-mercaptopurine therapy in selected cases of corticosteroid-dependent Crohn's disease.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Colonic Diseases; Crohn Disease; Female; Follow-U | 1991 |
Hermansky-Pudlak syndrome with granulomatous colitis in children.
Topics: Adrenal Cortex Hormones; Albinism, Oculocutaneous; Child; Child, Preschool; Crohn Disease; Female; H | 1991 |
Use of azathioprine in nine children with Crohn's disease.
Topics: Azathioprine; Child; Child, Preschool; Crohn Disease; Drug Therapy, Combination; Female; Humans; Mal | 1991 |
Enteral feeding versus drug therapy in Crohn's disease: a continuing story.
Topics: Adult; Child; Crohn Disease; Enteral Nutrition; Food, Formulated; Humans; Methylprednisolone; Sulfas | 1991 |
Peripheral blood neutrophils in inflammatory bowel disease: morphological evidence of in vivo activation in active disease.
Topics: Adult; Azathioprine; Blood Cell Count; Colitis, Ulcerative; Crohn Disease; Female; Humans; Inflammat | 1991 |
Acute sulfasalazine overdose.
Topics: Adult; Crohn Disease; Depressive Disorder; Drug Overdose; Humans; Male; Suicide, Attempted; Sulfasal | 1991 |
[Crohn disease in children].
Topics: Age Factors; Azathioprine; Child; Colectomy; Crohn Disease; Female; Humans; Male; Prednisolone; Sulf | 1991 |
[Crohn's colitis and parenteral nutrition].
Topics: Adrenal Cortex Hormones; Azathioprine; Colitis, Ulcerative; Crohn Disease; Female; Humans; Male; Par | 1991 |
[Changes in cell-mediated immune reactions in Crohn's disease].
Topics: Adult; Colitis; Crohn Disease; Drug Therapy, Combination; Female; Humans; Ileitis; Immunity, Cellula | 1991 |
[Pregnancy and chronic inflammatory bowel diseases].
Topics: Birth Weight; Colitis, Ulcerative; Crohn Disease; Female; Gestational Age; Humans; Infant, Newborn; | 1991 |
Clinical evidence supporting the radical scavenger mechanism of 5-aminosalicylic acid.
Topics: Adult; Aged; Aminosalicylic Acids; Biopsy; Colitis, Ulcerative; Colonic Diseases, Functional; Crohn | 1990 |
[Primary sclerosing cholangitis and inflammatory bowel disease].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Cholangiopancreatography, Endoscopic Retrograde; | 1990 |
A century of home parenteral nutrition for Crohn's disease.
Topics: Adult; Aged; Antidiarrheals; Crohn Disease; Female; Follow-Up Studies; Home Nursing; Hospitalization | 1990 |
Mesalazine: a global safety evaluation.
Topics: Aminosalicylic Acids; Crohn Disease; Dose-Response Relationship, Drug; Humans; Mesalamine; Sulfasala | 1990 |
[Pyoderma gangrenosum and Crohn's disease].
Topics: Adrenal Cortex Hormones; Adult; Crohn Disease; Drug Combinations; Glucosamine; Humans; Male; Metroni | 1990 |
Comparison of the single dose pharmacokinetics of sulphasalazine in rheumatoid arthritis and inflammatory bowel disease.
Topics: Adult; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Female; Humans; Male; Middle Aged; | 1990 |
Long-term 6-mercaptopurine treatment in adolescents with Crohn's disease.
Topics: Abscess; Adolescent; Adult; Anti-Bacterial Agents; Child; Crohn Disease; Drug Therapy, Combination; | 1990 |
Is trimethoprim-sulfamethoxazole helpful in Crohn's disease?
Topics: Adult; Crohn Disease; Drug Resistance; Female; Humans; Sulfasalazine; Trimethoprim, Sulfamethoxazole | 1990 |
[Crohn disease and ulcerative colitis].
Topics: Adrenal Cortex Hormones; Colitis, Ulcerative; Combined Modality Therapy; Crohn Disease; Cyclosporins | 1990 |
[Cryptogenetic ulcerative colitis. Our clinical experience with new therapeutic approaches].
Topics: Adrenal Cortex Hormones; Adult; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Diagnosis, | 1990 |
[Fistulas in Crohn disease--conservative versus operative treatment. The internist viewpoint].
Topics: Adolescent; Adult; Child; Combined Modality Therapy; Crohn Disease; Female; Humans; Intestinal Fistu | 1985 |
Does proctosigmoiditis in inflammatory bowel disease presage the imminent onset of symptoms?
Topics: Adolescent; Child; Child, Preschool; Colitis; Crohn Disease; Humans; Inflammatory Bowel Diseases; Me | 1989 |
Antimycobacterial chemotherapy in inflammatory bowel disease.
Topics: Adult; Anti-Bacterial Agents; Colitis, Ulcerative; Crohn Disease; Ethambutol; Female; Humans; Isonia | 1989 |
Crohn's disease, sulfasalazine, and mycobacteria.
Topics: Crohn Disease; Humans; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium tuberculosis; Struc | 1989 |
[A case of systemic lupus erythematosus with lupus nephritis occurring in Crohn's disease].
Topics: Adult; Crohn Disease; Humans; Lupus Erythematosus, Systemic; Lupus Nephritis; Male; Sulfasalazine | 1989 |
Management of bladder fistulas in Crohn's disease.
Topics: Adult; Analgesics; Anti-Bacterial Agents; Crohn Disease; Female; Humans; Intestinal Fistula; Male; M | 1989 |
[Therapy of Crohn disease].
Topics: Aminosalicylic Acids; Azathioprine; Colectomy; Crohn Disease; Diet; Glucocorticoids; Humans; Mercapt | 1989 |
Mesalazine in childhood inflammatory bowel disease.
Topics: Adolescent; Aminosalicylic Acids; Child; Child, Preschool; Colitis, Ulcerative; Crohn Disease; Femal | 1989 |
Favorable effect of 6-mercaptopurine on fistulae of Crohn's disease.
Topics: Abdominal Muscles; Adolescent; Adult; Crohn Disease; Double-Blind Method; Female; Fistula; Humans; I | 1985 |
Arachidonic acid metabolites and their role in inflammatory bowel disease. An update requiring addition of a pathway.
Topics: Aminosalicylic Acids; Arachidonic Acid; Arachidonic Acids; Biological Transport; Bradykinin; Colitis | 1985 |
Disposition of disodium azodisalicylate in healthy subjects. A possible new drug for inflammatory bowel disease.
Topics: Administration, Oral; Aminosalicylic Acids; Crohn Disease; Half-Life; Humans; Kinetics; Mesalamine; | 1985 |
[Therapeutic experience with ulcerative colitis and Crohn disease].
Topics: Adrenal Cortex Hormones; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Combinations; Drug T | 1985 |
[Crohn disease: initial experiences with cyclosporin A in an adolescent girl].
Topics: Adolescent; Azathioprine; Crohn Disease; Cyclosporins; Female; Humans; Lymphoma; Osteoporosis; Predn | 1985 |
Antiinflammatory treatment and intestinal alpha 1-antitrypsin clearance in active Crohn's disease.
Topics: Adolescent; Adult; alpha 1-Antitrypsin; Anti-Inflammatory Agents; Crohn Disease; Feces; Female; Huma | 1985 |
Pyostomatitis vegetans.
Topics: Biopsy; Crohn Disease; Female; Humans; Middle Aged; Mouth Mucosa; Prednisone; Stomatitis; Sulfasalaz | 1985 |
Sulfasalazine and renal tubular function: lack of an effect.
Topics: Adolescent; beta 2-Microglobulin; Child; Crohn Disease; Epithelium; Humans; Kidney Function Tests; K | 1985 |
[Differential therapy of Crohn disease].
Topics: Combined Modality Therapy; Crohn Disease; Food, Formulated; Humans; Immunosuppressive Agents; Intest | 1985 |
Oral manifestations in Crohn's disease: report of a case.
Topics: Adolescent; Barium Sulfate; Colon; Colonoscopy; Crohn Disease; Duodenoscopy; Esophagus; Gastrointest | 1985 |
Pregnancy, fertility, and inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Azathioprine; Colitis, Ulcerative; Crohn Disease; Fe | 1985 |
The effect of rifampicin on sulphapyridine plasma concentrations following sulphasalazine administration.
Topics: Adult; Crohn Disease; Drug Interactions; Ethambutol; Female; Humans; Male; Middle Aged; Rifampin; Su | 1985 |
Crohn's disease with persistence of Clostridium difficile, surgical elimination.
Topics: Adolescent; Clostridium; Crohn Disease; Cytotoxins; Drug Resistance, Microbial; Humans; Male; Predni | 1985 |
Hepatic portal venous gas after colonoscopy in granulomatous colitis.
Topics: Abdomen; Adult; Colonoscopy; Combined Modality Therapy; Crohn Disease; Embolism, Air; Humans; Male; | 1985 |
Isotypic analysis of antibody response to a food antigen in inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Animals; Antibody Formation; Antibody Specificity; Antigen-Antibody Complex | 1985 |
Crohn's ileitis complicated by amyloidosis: observations and therapeutic considerations.
Topics: Adult; Amyloidosis; Biopsy; Colchicine; Crohn Disease; Diagnosis, Differential; Familial Mediterrane | 1985 |
Inflammatory bowel disease in the pregnant woman.
Topics: Abdomen; Adrenal Cortex Hormones; Adult; Animals; Breast Feeding; Colitis, Ulcerative; Crohn Disease | 1985 |
Idiopathic pancreatitis associated with inflammatory bowel disease.
Topics: Adolescent; Adult; Colitis, Ulcerative; Crohn Disease; Exocrine Pancreatic Insufficiency; Female; Hu | 1985 |
Retention of sulfasalazine tablets.
Topics: Crohn Disease; Female; Humans; Intestinal Obstruction; Middle Aged; Sulfasalazine; Tablets, Enteric- | 1985 |
[Salazosulfapyridine: old and new therapy concepts in inflammatory bowel diseases].
Topics: Colitis, Ulcerative; Crohn Disease; Delayed-Action Preparations; Enema; Humans; Sulfasalazine; Suppo | 1985 |
Gastrocnemius myositis in a patient with inflammatory bowel disease.
Topics: Adenocarcinoma; Adult; Colectomy; Colon; Colonic Neoplasms; Crohn Disease; Female; Humans; Myositis; | 1985 |
[Crohn's disease in children and adolescents].
Topics: Adolescent; Anemia; Child; Crohn Disease; Drug Therapy, Combination; Female; Growth Disorders; Human | 1985 |
[Conservative and surgical treatment of Leśniowski-Crohn disease of the colon].
Topics: Adolescent; Colectomy; Colitis; Crohn Disease; Drug Therapy, Combination; Female; Humans; Prednisone | 1985 |
Hydrostatic balloon dilation of a terminal ileal stricture secondary to Crohn's disease.
Topics: Adult; Crohn Disease; Dilatation; Female; Follow-Up Studies; Humans; Ileal Diseases; Intestinal Obst | 1986 |
Therapeutical experiments in ulcerative colitis and Crohn's disease.
Topics: Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Therapy, Combination; Follow-Up Studies; Huma | 1985 |
The value of 5-aminosalicylic acid in inflammatory bowel disease for patients intolerant or allergic to sulphasalazine.
Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Drug Hypersensitivity; Humans; Mesa | 1985 |
Pyoderma gangrenosum involving the head and neck.
Topics: Adrenal Cortex Hormones; Adult; Aged; Biopsy; Colitis, Ulcerative; Crohn Disease; Drug Therapy, Comb | 1986 |
Esophageal stricture in Crohn's disease--a case report.
Topics: Crohn Disease; Esophageal Diseases; Esophageal Stenosis; Humans; Male; Middle Aged; Prednisolone; Su | 1986 |
[Exacerbation of ulcerative colitis and Crohn's disease following a change-over from salazosulfapyridine to 5-aminosalicylic acid].
Topics: Adolescent; Adult; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Female; Humans; Male; M | 1986 |
Hepatotoxicity after treatment with sulfasalazine.
Topics: Adult; Chemical and Drug Induced Liver Injury; Crohn Disease; Drug Eruptions; Drug Hypersensitivity; | 1986 |
Disposition of metronidazole and its effects on sulphasalazine metabolism in patients with inflammatory bowel disease.
Topics: Administration, Oral; Biological Availability; Colitis, Ulcerative; Crohn Disease; Drug Evaluation; | 1986 |
[Ulcerative colitis and Crohn disease. Early diagnosis and therapy].
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Combined Modality Therapy; Crohn Disease; Humans; Intesti | 1986 |
Inhibition of cytotoxicity by sulfasalazine. I. Sulfasalazine inhibits spontaneous cell-mediated cytotoxicity by peripheral blood and intestinal mononuclear cells from control and inflammatory bowel disease patients.
Topics: Catechols; Colitis, Ulcerative; Crohn Disease; Cytotoxicity, Immunologic; Humans; Hydrocortisone; In | 1986 |
Male fertility in Crohn's disease.
Topics: Adrenal Cortex Hormones; Adult; Aged; Crohn Disease; Family Characteristics; Humans; Infertility, Ma | 1986 |
Myositis associated with Crohn's colitis.
Topics: Adult; Autoimmune Diseases; Creatine Kinase; Crohn Disease; Humans; Male; Myositis; Sulfasalazine | 1986 |
Zinc absorption in inflammatory bowel disease.
Topics: Adult; Aged; Chlorides; Colitis, Ulcerative; Crohn Disease; Drug Therapy, Combination; Female; Food; | 1986 |
[Metronidazole treatment of Crohn disease].
Topics: Crohn Disease; Drug Therapy, Combination; Humans; Metronidazole; Prednisone; Sulfasalazine | 1986 |
[Pulmonary diffusing capacity disorder in nonspecific intestinal inflammations unexplainable by acetylation phenotype or treatment with sulfasalazine].
Topics: Acetylation; Adult; Colitis, Ulcerative; Crohn Disease; Female; Humans; Male; Middle Aged; Phenotype | 1986 |
[Exacerbation of ulcerative colitis and Crohn disease as a phenomenon inherent in the disease].
Topics: Colitis, Ulcerative; Crohn Disease; Humans; Sulfasalazine | 1986 |
Clostridium difficile toxin in chronic idiopathic colitis.
Topics: Adult; Bacterial Proteins; Bacterial Toxins; Chronic Disease; Clostridium; Clostridium Infections; C | 1986 |
Enhanced formation of sulfidopeptide-leukotrienes in ulcerative colitis and Crohn's disease: inhibition by sulfasalazine and 5-aminosalicylic acid.
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Humans; Intestinal Mucosa; Kinetics; Leuko | 1986 |
[Erythema nodosum in hemorrhagic rectocolitis and Crohn's disease].
Topics: Adolescent; Adult; Aged; Colitis, Ulcerative; Crohn Disease; Drug Combinations; Erythema Nodosum; Fe | 1986 |
[Crohn disease in childhood].
Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Azathioprine; Child; Combined Modality Therapy; Crohn | 1986 |
The immunology of idiopathic inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Colitis, Ulcerative; Colonic Diseases; Crohn Disease; Diagnosis, Differenti | 1986 |
Sulphasalazine in inflammatory bowel disease: recent advances.
Topics: Administration, Oral; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Enema; Humans; Mesal | 1986 |
[Defined formula diet in the treatment of active Crohn disease].
Topics: Adult; Crohn Disease; Drug Therapy, Combination; Enteral Nutrition; Female; Food, Formulated; Humans | 1986 |
Comparison of white blood cell dyscrasias during sulphasalazine therapy of rheumatoid arthritis and inflammatory bowel disease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Dis | 1986 |
[Development of a prognostic index in Crohn disease].
Topics: Crohn Disease; Drug Therapy, Combination; Humans; Methylprednisolone; Prognosis; Sulfasalazine | 1987 |
Sulphasalazine and sulphapyridine serum levels in children to mothers treated with sulphasalazine during pregnancy and lactation.
Topics: Colitis, Ulcerative; Crohn Disease; Female; Humans; Infant, Newborn; Lactation; Maternal-Fetal Excha | 1987 |
[Treatment of chronic inflammatory intestinal diseases with 5-aminosalicylic acid].
Topics: Administration, Oral; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Enema; Humans; Mesal | 1987 |
[Eicosanoids in chronic inflammatory intestinal diseases].
Topics: Arachidonic Acids; Colitis, Ulcerative; Crohn Disease; Eicosanoic Acids; Humans; Intestinal Mucosa; | 1987 |
1986 Stuart distinguished lecture. The "natural history" of inflammatory bowel disease and therapeutic decisions.
Topics: Adrenocorticotropic Hormone; Colectomy; Colitis, Ulcerative; Colon; Cortisone; Crohn Disease; Dilata | 1987 |
[A young woman with Crohn's disease of the esophagus].
Topics: Adult; Barium Sulfate; Colitis; Crohn Disease; Drug Combinations; Esophagitis; Esophagoscopy; Female | 1987 |
Favorable effects of sulfasalazine on small bowel Crohn's disease: a long-term study.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Crohn Disease; Female; Humans; Intestine, Small; Male | 1987 |
Leukotrienes in Crohn's disease: effect of sulfasalazine and 5-aminosalicylic acid.
Topics: Aminosalicylic Acids; Colon; Crohn Disease; Dinoprostone; Humans; In Vitro Techniques; Intestinal Mu | 1987 |
Possible mode of action of 5-aminosalicylic acid.
Topics: Aminosalicylic Acids; Arachidonic Acid; Arachidonic Acids; Arthritis, Rheumatoid; Colitis, Ulcerativ | 1987 |
Relationships between drug regime and histology of rectal mucosa in Crohn's disease.
Topics: Crohn Disease; Humans; Intestinal Mucosa; Prednisolone; Rectum; Statistics as Topic; Sulfasalazine | 1988 |
Sulfasalazine: I. An historical perspective.
Topics: Animals; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; History, 20th Century; Humans; S | 1988 |
Pentasa in lieu of sulfasalazine.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Humans; Mesalamin | 1988 |
Epidermolysis bullosa acquisita and Crohn's disease. A case report with immunological and electron microscopic studies.
Topics: Adult; Crohn Disease; Epidermolysis Bullosa; Fluorescent Antibody Technique; Humans; Immunoenzyme Te | 1988 |
[Drug treatment of chronic inflammatory diseases of the intestine].
Topics: Anti-Inflammatory Agents; Colitis, Ulcerative; Crohn Disease; Humans; Sulfasalazine | 1988 |
Undissolved sulfasalazine tablets.
Topics: Administration, Oral; Crohn Disease; Humans; Sulfasalazine; Tablets | 1988 |
Medical management: its accomplishments in Crohn's disease and indications for surgery.
Topics: Adrenal Cortex Hormones; Crohn Disease; Drug Therapy, Combination; Humans; Immunosuppressive Agents; | 1988 |
Diet counselling improves the clinical course of patients with Crohn's disease.
Topics: Adolescent; Adult; Aged; Crohn Disease; Female; Humans; Male; Middle Aged; Nutritional Physiological | 1988 |
Cutaneous Crohn's disease and progressive vitiligo.
Topics: Adult; Colonic Diseases; Crohn Disease; Female; Granuloma; Humans; Remission, Spontaneous; Skin Dise | 1988 |
[Depression induced by salazosulfapyridine in cyclothymia and Crohn disease].
Topics: Adolescent; Crohn Disease; Cyclothymic Disorder; Depressive Disorder; Dose-Response Relationship, Dr | 1988 |
Sulphasalazine and inflammatory bowel disease.
Topics: Arthritis, Rheumatoid; Crohn Disease; Enema; Humans; Sulfasalazine; Tablets, Enteric-Coated | 1987 |
Olsalazine as an alternative therapy in a patient with sulfasalazine-induced eosinophilic pneumonia.
Topics: Adult; Aminosalicylic Acids; Colitis; Crohn Disease; Humans; Male; Pulmonary Eosinophilia; Sulfasala | 1988 |
[Drug information. Pentasa--new Danish drug].
Topics: Colitis, Ulcerative; Crohn Disease; Delayed-Action Preparations; Humans; Sulfasalazine | 1988 |
Disposition of 5-aminosalicylic acid by 5-aminosalicylic acid-delivering compounds.
Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Delayed-Action Preparations; Female | 1988 |
[Acute manifestations in Crohn disease and ulcerative colitis. Conservative treatment of acute situations].
Topics: Acute Disease; Aminosalicylic Acids; Colitis, Ulcerative; Combined Modality Therapy; Crohn Disease; | 1988 |
[Recent progress in diagnosis and treatment of digestive diseases. III. Inflammatory bowel diseases. 7. Medical treatment of ulcerative colitis and Crohn's disease].
Topics: Adrenocorticotropic Hormone; Colitis, Ulcerative; Crohn Disease; Drug Combinations; Glucosamine; Hum | 1988 |
Impaired folic acid absorption in inflammatory bowel disease: effects of salicylazosulfapyridine (Azulfidine).
Topics: Adolescent; Adult; Animals; Biological Assay; Colitis, Ulcerative; Crohn Disease; Depression, Chemic | 1973 |
Crohn's disease: a clinical study of 75 patients.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Child; Crohn Disease; Female; Fol | 1973 |
Regional enteritis and growth retardation without intestinal symptoms.
Topics: Adolescent; Anemia, Hypochromic; Body Weight; Crohn Disease; Follow-Up Studies; Growth Disorders; Hu | 1973 |
Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype.
Topics: Acetylation; Agranulocytosis; Aminosalicylic Acids; Anemia, Hemolytic; Colitis, Ulcerative; Crohn Di | 1973 |
II. Medical treatment of inflammatory bowel disease.
Topics: Administration, Oral; Azathioprine; Colitis, Ulcerative; Crohn Disease; Enema; Glucocorticoids; Huma | 1973 |
Mesenteric angiographic studies in children with regional enteritis.
Topics: Adolescent; Age Factors; Angiography; Atropa belladonna; Blood Sedimentation; Child; Chlordiazepoxid | 1973 |
Letter: Salicylazosulfapyridine in clinical practice.
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Humans; Sulfanilamides; Sulfasalazine | 1974 |
Development of carcinoma in regional enteritis.
Topics: Adenocarcinoma, Mucinous; Barium Sulfate; Cecum; Colon; Colonic Diseases; Crohn Disease; Enema; Fluo | 1974 |
[Regional enteritis Crohn (author's transl)].
Topics: Adult; Arthritis, Rheumatoid; Azathioprine; Colitis, Ulcerative; Crohn Disease; Diagnosis, Different | 1973 |
The role of the colon in the metabolism of salicylazosulphapyridine.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Colectomy; Colitis, Ulcerative; Colon; Colostomy; Cro | 1974 |
Crohn's disease of the mouth.
Topics: Administration, Topical; Adolescent; Anti-Inflammatory Agents; Barium Sulfate; Biopsy; Crohn Disease | 1974 |
The drug therapy of ulcerative colitis and of Crohn's disease.
Topics: Adrenocorticotropic Hormone; Atropine; Azathioprine; Colitis, Ulcerative; Crohn Disease; Diarrhea; D | 1974 |
Systemic granulomatous reaction to salicylazosulfapyridine (Azulfidine) in a patient with Crohn's disease.
Topics: Adult; Biopsy; Chemical and Drug Induced Liver Injury; Crohn Disease; Diagnosis, Differential; Femal | 1974 |
[Colitis--newer aspects upon ulcerative colitis and Crohn's disease in the colon].
Topics: Adolescent; Adult; Animals; Child; Colitis, Ulcerative; Colon; Crohn Disease; Diagnosis, Differentia | 1973 |
Proceedings: Effects of sulphasalazine (Salazopyrin) on faecal flora in patients with inflammatory bowel disease.
Topics: Bacteroides; Clostridium; Colitis, Ulcerative; Crohn Disease; Eubacterium; Feces; Humans; Sulfasalaz | 1974 |
[Crohn's disease (author's transl)].
Topics: Adolescent; Adult; Crohn Disease; Female; Humans; Male; Middle Aged; Postoperative Complications; Pr | 1974 |
Medical treatment of Crohn's disease.
Topics: Adrenal Cortex Hormones; Azathioprine; Crohn Disease; Humans; Sulfasalazine; Vitamin B 12 | 1974 |
[Progress in inflammatory diseases of the colon (author's transl)].
Topics: Chemical Phenomena; Chemistry; Colitis, Ulcerative; Crohn Disease; Glucocorticoids; Humans; Immunosu | 1974 |
[Crohn's disease in the colon].
Topics: Adult; Colonic Diseases; Colostomy; Crohn Disease; Diverticulitis, Colonic; Drug Therapy, Combinatio | 1974 |
[Study of the course of Crohn's disease under Imurel treatment].
Topics: Adult; Aged; Azathioprine; Blood Sedimentation; Crohn Disease; Female; Glucocorticoids; Hemoglobins; | 1974 |
Psychological management of Crohn's disease.
Topics: Adult; Aggression; Colitis, Ulcerative; Crohn Disease; Diazepam; Divorce; Female; Humans; Illegitima | 1974 |
Effects of sulphasalazine (Salazopyrin) on faecal flora in patients with inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aged; Bacteroides; Clostridium; Colitis | 1974 |
Regional enteritis in adolescence.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Analgesics; Child; Chlordiazepoxide; Crohn Disease; Fema | 1967 |
[Chronic regional enterocolitis (Crohn's disease) in juveniles].
Topics: Adolescent; Blood Transfusion; Child; Colitis, Ulcerative; Crohn Disease; Diagnosis, Differential; F | 1967 |
[51. Inflammatory diseases of the large intestine. (Internistic report)].
Topics: Adrenal Cortex Hormones; Colitis, Ulcerative; Crohn Disease; Diagnosis, Differential; Humans; Inflam | 1967 |
Urine indican excretion in malabsorptive disorders.
Topics: Celiac Disease; Crohn Disease; Diagnosis, Differential; Feces; Humans; Indican; Intestinal Absorptio | 1968 |
[Regional enteritis].
Topics: Acute Disease; Adult; Age Factors; Chronic Disease; Crohn Disease; Diagnosis, Differential; Diet The | 1968 |
[2 cases of Crohn's disease].
Topics: Adrenocorticotropic Hormone; Adult; Asthenia; Colectomy; Crohn Disease; Dilatation; Humans; Intestin | 1969 |
Some epidemiological observations on the etiology of regional enteritis.
Topics: Adolescent; Adult; Age Factors; Aged; Animals; Butter; Child; Child, Preschool; Crohn Disease; Diet | 1969 |
[Hemorrhagic rectocolitis in children].
Topics: Adolescent; Age Factors; Anus Diseases; Betamethasone; Blepharitis; Child; Child, Preschool; Colitis | 1969 |
Pancreatitis as an adverse reaction to salicylazosulfapyridine.
Topics: Adult; Amylases; Crohn Disease; Female; Humans; Pancreatitis; Sulfasalazine | 1970 |
[Azathioprine therapy in regional enteritis (Crohn's disease)].
Topics: Adult; Azathioprine; Colon, Sigmoid; Crohn Disease; Female; Humans; Ileum; Intestinal Mucosa; Intest | 1970 |
Observations on the treatment of colitis.
Topics: Adrenal Cortex Hormones; Colectomy; Colitis, Ulcerative; Crohn Disease; Enema; Humans; Life Expectan | 1971 |
Clinical and radiologic improvement of regional enteritis and enterocolitis after treatment with salicylazosulfapyridine.
Topics: Adolescent; Adult; Aged; Cecum; Colitis; Colon; Crohn Disease; Female; Humans; Ileum; Male; Radiogra | 1971 |
Medical versus operative treatment.
Topics: Child; Colitis, Ulcerative; Crohn Disease; Female; Humans; Male; Retrospective Studies; Sulfasalazin | 1971 |
Psoas abscess in Crohn's disease.
Topics: Abscess; Adolescent; Adult; Bacillus; Clostridium; Crohn Disease; Drainage; Escherichia coli; Female | 1971 |
[Perianal ulceration as a diagnostic pathway to Crohn's regional enteritis].
Topics: Administration, Topical; Adrenal Cortex Hormones; Anal Canal; Anti-Bacterial Agents; Anti-Inflammato | 1971 |
The effect of salazopyrin on water and electrolyte transport in the human colon measured in vivo and in vitro.
Topics: Colitis, Ulcerative; Colon; Crohn Disease; Humans; In Vitro Techniques; Intestinal Absorption; Potas | 1972 |
Crohn's disease with mouth involvement.
Topics: Adult; Crohn Disease; Humans; Male; Prednisolone; Stomatitis; Sulfasalazine | 1972 |
Imparied lymphocyte responsiveness in inflammatory bowel disease.
Topics: Colitis, Ulcerative; Crohn Disease; Deoxyuridine; Humans; Iodine Isotopes; Lectins; Lymphocyte Activ | 1973 |