sulfasalazine has been researched along with Cocarcinogenesis in 3 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Cocarcinogenesis: The combination of two or more different factors in the production of cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An increased incidence of colonic cancer is associated with chronic inflammatory bowel disease." | 1.28 | The effect of therapeutic drugs used in inflammatory bowel disease on the incidence and growth of colonic cancer in the dimethylhydrazine rat model. ( Crouch, R; Davis, AE; Patterson, F, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wada, T | 1 |
| Ishimoto, T | 1 |
| Seishima, R | 1 |
| Tsuchihashi, K | 1 |
| Yoshikawa, M | 1 |
| Oshima, H | 1 |
| Oshima, M | 1 |
| Masuko, T | 1 |
| Wright, NA | 1 |
| Furuhashi, S | 1 |
| Hirashima, K | 1 |
| Baba, H | 1 |
| Kitagawa, Y | 1 |
| Saya, H | 1 |
| Nagano, O | 1 |
| Meenan, J | 1 |
| Davis, AE | 1 |
| Patterson, F | 1 |
| Crouch, R | 1 |
3 other studies available for sulfasalazine and Cocarcinogenesis
| Article | Year |
|---|---|
Functional role of CD44v-xCT system in the development of spasmolytic polypeptide-expressing metaplasia.
Topics: Adenocarcinoma; Amino Acid Transport System y+; Animals; Biomarkers, Tumor; Cell Transformation, Neo | 2013 |
Co-carcinogenic effect of sulphasalazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cocarcinogenesis; Dimethylhydrazines; Folic Acid Defici | 1993 |
The effect of therapeutic drugs used in inflammatory bowel disease on the incidence and growth of colonic cancer in the dimethylhydrazine rat model.
Topics: Adenocarcinoma; Aminosalicylic Acids; Animals; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazin | 1992 |