sulfasalazine has been researched along with Cirrhosis in 5 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effects of sulfasalazine (SF) on pancreatic inflammation and fibrogenesis." | 7.83 | Sulfasalazine inhibits inflammation and fibrogenesis in pancreas via NF-κB signaling pathway in rats with oxidative stress-induced pancreatic injury. ( Fan, JH; Kuang, RG; Li, YQ; Tian, FL; Wang, LY; Wang, YR; Yan, MX, 2016) |
| "The purpose of this study was to test whether sulfasalazine has a protective action against interstitial inflammation and the development of renal fibrosis in obstructive nephropathy." | 7.74 | Sulfasalazine reduces inflammatory renal injury in unilateral ureteral obstruction. ( Akin, M; Aksoy, RT; Ay, S; Aydin, EN; Demirbilek, S; Edali, MN; Emre, MH; Gürünlüoğlu, K; Tas, E; Yilmaz, Z, 2007) |
| "Fibrosis/contracture is associated with the abnormal persistence of myofibroblasts, which over-produce and contract collagen matrices." | 5.56 | Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis. ( Atluri, K; Brouillette, MJ; Fowler, TP; Fredericks, D; Khorsand, B; Martin, JA; Petersen, E; Salem, AK; Sander, E; Seol, D; Smith, S, 2020) |
| " Angiotensin II (AngII) results in cardiac fibrosis and hypertrophy partly through activation of inflammation, which increases the fibroblasts and promotes extracellular matrix production." | 4.12 | Sulfasalazine exacerbates angiotensin II-induced cardiac remodelling by activating Akt signal pathway. ( Bai, Y; Chen, C; Gao, Z; Jiang, X; Meng, Y; Zhang, X; Zheng, C, 2022) |
| "To investigate the effects of sulfasalazine (SF) on pancreatic inflammation and fibrogenesis." | 3.83 | Sulfasalazine inhibits inflammation and fibrogenesis in pancreas via NF-κB signaling pathway in rats with oxidative stress-induced pancreatic injury. ( Fan, JH; Kuang, RG; Li, YQ; Tian, FL; Wang, LY; Wang, YR; Yan, MX, 2016) |
| "The purpose of this study was to test whether sulfasalazine has a protective action against interstitial inflammation and the development of renal fibrosis in obstructive nephropathy." | 3.74 | Sulfasalazine reduces inflammatory renal injury in unilateral ureteral obstruction. ( Akin, M; Aksoy, RT; Ay, S; Aydin, EN; Demirbilek, S; Edali, MN; Emre, MH; Gürünlüoğlu, K; Tas, E; Yilmaz, Z, 2007) |
| "Fibrosis/contracture is associated with the abnormal persistence of myofibroblasts, which over-produce and contract collagen matrices." | 1.56 | Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis. ( Atluri, K; Brouillette, MJ; Fowler, TP; Fredericks, D; Khorsand, B; Martin, JA; Petersen, E; Salem, AK; Sander, E; Seol, D; Smith, S, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, C | 1 |
| Zhang, X | 1 |
| Zheng, C | 1 |
| Gao, Z | 1 |
| Jiang, X | 1 |
| Bai, Y | 1 |
| Meng, Y | 1 |
| Atluri, K | 1 |
| Brouillette, MJ | 1 |
| Seol, D | 1 |
| Khorsand, B | 1 |
| Sander, E | 1 |
| Salem, AK | 1 |
| Fredericks, D | 1 |
| Petersen, E | 1 |
| Smith, S | 1 |
| Fowler, TP | 1 |
| Martin, JA | 1 |
| Wang, YR | 1 |
| Tian, FL | 1 |
| Yan, MX | 1 |
| Fan, JH | 1 |
| Wang, LY | 1 |
| Kuang, RG | 1 |
| Li, YQ | 1 |
| Demirbilek, S | 1 |
| Emre, MH | 1 |
| Aydin, EN | 1 |
| Edali, MN | 1 |
| Aksoy, RT | 1 |
| Akin, M | 1 |
| Gürünlüoğlu, K | 1 |
| Tas, E | 1 |
| Ay, S | 1 |
| Yilmaz, Z | 1 |
| Tandon, RK | 1 |
| Atmakuri, SP | 1 |
| Mehra, NK | 1 |
| Malaviya, AN | 1 |
| Tandon, HD | 1 |
| Chopra, P | 1 |
5 other studies available for sulfasalazine and Cirrhosis
| Article | Year |
|---|---|
Sulfasalazine exacerbates angiotensin II-induced cardiac remodelling by activating Akt signal pathway.
Topics: Angiotensin II; Animals; Cardiomegaly; Fibrosis; Hypertrophy; Mice; Mice, Inbred C57BL; Myocardium; | 2022 |
Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis.
Topics: Aminopropionitrile; Animals; Collagen; Contracture; Disease Models, Animal; Fibrosis; Hydroxyproline | 2020 |
Sulfasalazine inhibits inflammation and fibrogenesis in pancreas via NF-κB signaling pathway in rats with oxidative stress-induced pancreatic injury.
Topics: Animals; Fibrosis; Inflammation; Injections, Intraperitoneal; NF-kappa B; Oxidative Stress; Pancreas | 2016 |
Sulfasalazine reduces inflammatory renal injury in unilateral ureteral obstruction.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catalase; Female; Fibrosis; Free Radical Scavenger | 2007 |
Is solitary rectal ulcer a manifestation of a systemic disease?
Topics: Adolescent; Adult; Aged; Arthritis; Female; Fibrosis; HLA-B27 Antigen; Humans; Male; Middle Aged; Pr | 1990 |