sulfasalazine has been researched along with Cholestasis, Intrahepatic in 1 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Cholestasis, Intrahepatic: Impairment of bile flow due to injury to the HEPATOCYTES; BILE CANALICULI; or the intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 55-year-old woman with rheumatoid arthritis in overlap with polymyositis received sulfasalazine for control of synovitis." | 7.67 | Cholestasis and fatal agranulocytosis complicating sulfasalazine therapy: case report and review of the literature. ( Mitrane, MP; Seibold, JR; Singh, A, 1986) |
| "A 55-year-old woman with rheumatoid arthritis in overlap with polymyositis received sulfasalazine for control of synovitis." | 3.67 | Cholestasis and fatal agranulocytosis complicating sulfasalazine therapy: case report and review of the literature. ( Mitrane, MP; Seibold, JR; Singh, A, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mitrane, MP | 1 |
| Singh, A | 1 |
| Seibold, JR | 1 |
1 other study available for sulfasalazine and Cholestasis, Intrahepatic
| Article | Year |
|---|---|
Cholestasis and fatal agranulocytosis complicating sulfasalazine therapy: case report and review of the literature.
Topics: Agranulocytosis; Arthritis, Rheumatoid; Cholestasis, Intrahepatic; Female; Humans; Middle Aged; Myos | 1986 |