sulfasalazine has been researched along with Cholera Infantum in 26 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the benefits and side effects of TwHF extract with those of sulfasalazine for the treatment of active rheumatoid arthritis." | 9.14 | Comparison of Tripterygium wilfordii Hook F versus sulfasalazine in the treatment of rheumatoid arthritis: a randomized trial. ( Costello, R; Csako, G; Fleischmann, R; Goldbach-Mansky, R; Kempf, P; Kivitz, A; Lipsky, PE; Olsen, N; Pham, TH; Pucino, F; Sherrer, Y; Silverfield, J; Snyder, C; Tao, X; van der Heijde, D; Wesley, R; Wilson, M, 2009) |
| "To compare the benefits and side effects of TwHF extract with those of sulfasalazine for the treatment of active rheumatoid arthritis." | 5.14 | Comparison of Tripterygium wilfordii Hook F versus sulfasalazine in the treatment of rheumatoid arthritis: a randomized trial. ( Costello, R; Csako, G; Fleischmann, R; Goldbach-Mansky, R; Kempf, P; Kivitz, A; Lipsky, PE; Olsen, N; Pham, TH; Pucino, F; Sherrer, Y; Silverfield, J; Snyder, C; Tao, X; van der Heijde, D; Wesley, R; Wilson, M, 2009) |
| "The main aim of this study was to examine the differences between triple therapy (T: SSZ and HCQ added to MTX) and etanercept (E) added to MTX with regard to the infectious and gastrointestinal (GI) adverse events (AEs) reported in The Rheumatoid Arthritis Comparison of Active Therapies Trial." | 2.84 | Rheumatoid arthritis triple therapy compared with etanercept: difference in infectious and gastrointestinal adverse events. ( Brophy, MT; Chang, BH; Hannagan, K; O'Dell, JR; Quach, LT; Soe Thwin, S, 2017) |
| "Eighty-five patients with active ankylosing spondylitis (AS) were randomized to receive either sulfasalazine (less than or equal to 3 gm/day, mean 2." | 2.66 | Sulfasalazine in the treatment of ankylosing spondylitis. A twenty-six-week, placebo-controlled clinical trial. ( Lehtinen, K; Leirisalo-Repo, M; Luukkainen, R; Mutru, O; Nissilä, M; Yli-Kerttula, U, 1988) |
| "To evaluate rates on the adverse side effect and discontinuation of second-line drugs frequently used in the treatment of rheumatoid arthritis (RA)." | 1.31 | [Retrospective study of adverse events in patients with rheumatoid arthritis treated with second-line drugs]. ( Jiang, L; Ni, L; Zhao, N, 2002) |
| " Serious or fatal adverse reactions were not observed." | 1.29 | Toxicity of sulphasalazine in rheumatoid arthritis. Possible protective effect of rheumatoid factors and corticosteroids. ( Gran, JT; Myklebust, G, 1993) |
| "These are all beneficial in treating gastroduodenal ulceration." | 1.27 | The role of arachidonic acid metabolites in gastrointestinal homeostasis. Biochemical, histological and clinical gastrointestinal effects. ( Isselbacher, KJ, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (53.85) | 18.7374 |
| 1990's | 5 (19.23) | 18.2507 |
| 2000's | 4 (15.38) | 29.6817 |
| 2010's | 3 (11.54) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hoversten, P | 1 |
| Beachey, J | 1 |
| Pham, M | 1 |
| Bhagra, A | 1 |
| Quach, LT | 1 |
| Chang, BH | 1 |
| Brophy, MT | 1 |
| Soe Thwin, S | 1 |
| Hannagan, K | 1 |
| O'Dell, JR | 1 |
| Goldbach-Mansky, R | 1 |
| Wilson, M | 1 |
| Fleischmann, R | 1 |
| Olsen, N | 1 |
| Silverfield, J | 1 |
| Kempf, P | 1 |
| Kivitz, A | 1 |
| Sherrer, Y | 1 |
| Pucino, F | 1 |
| Csako, G | 1 |
| Costello, R | 1 |
| Pham, TH | 1 |
| Snyder, C | 1 |
| van der Heijde, D | 1 |
| Tao, X | 1 |
| Wesley, R | 1 |
| Lipsky, PE | 1 |
| Jiang, M | 1 |
| Zhao, J | 1 |
| Lu, A | 1 |
| Zha, Q | 1 |
| He, Y | 1 |
| Jiang, L | 1 |
| Zhao, N | 1 |
| Ni, L | 1 |
| Schiemann, U | 1 |
| Kellner, H | 1 |
| DICK, AP | 1 |
| GRAYSON, MJ | 1 |
| CARPENTER, RG | 1 |
| PETRIE, A | 1 |
| EWE, K | 1 |
| Taffet, SL | 1 |
| Das, KM | 1 |
| Gran, JT | 1 |
| Myklebust, G | 1 |
| Morgan, SL | 1 |
| Baggott, JE | 1 |
| Alarcón, GS | 1 |
| Parente, F | 1 |
| Molteni, P | 1 |
| Bollani, S | 1 |
| Maconi, G | 1 |
| Vago, L | 1 |
| Duca, PG | 1 |
| Rembacken, B | 1 |
| Axon, AT | 1 |
| Bianchi Porro, G | 1 |
| Bennett, A | 1 |
| Isaev, VI | 1 |
| Pugovkin, VS | 1 |
| Matsuoka, Y | 1 |
| Yamamoto, S | 1 |
| Nakamura, M | 1 |
| Tanaka, S | 1 |
| Araki, M | 1 |
| Shizuku, T | 1 |
| Fujita, Y | 1 |
| Tsuboi, S | 1 |
| Okamoto, S | 1 |
| Miura, H | 1 |
| Donovan, S | 1 |
| Hawley, S | 1 |
| MacCarthy, J | 1 |
| Scott, DL | 1 |
| Muirden, KD | 1 |
| Woodhouse, KW | 1 |
| MacDermott, RP | 1 |
| Astbury, C | 1 |
| Taggart, AJ | 1 |
| Isselbacher, KJ | 1 |
| McConkey, B | 1 |
| Nissilä, M | 1 |
| Lehtinen, K | 1 |
| Leirisalo-Repo, M | 1 |
| Luukkainen, R | 1 |
| Mutru, O | 1 |
| Yli-Kerttula, U | 1 |
| Arvanitakis, C | 1 |
| Manier, JW | 1 |
| Kaufmann, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| CSP #551 - Rheumatoid Arthritis: Comparison of Active Therapies in Patients With Active Disease Despite Methotrexate Therapy[NCT00405275] | 353 participants (Actual) | Interventional | 2007-07-31 | Completed | |||
| A Randomized, Controlled, Open-label Study to Assess the Efficacy of T2 Versus Azathioprine for the Maintenance of Clinical and Endoscopic Remission in Subjects With Crohn's Disease After Surgical Resection[NCT01015391] | 100 participants (Anticipated) | Interventional | 2009-11-30 | Recruiting | |||
| Phase 1/2 Study of Tripterygium Wilfordii Hook F (TwHF) Treatment for Evaluation the Efficacy and Safety in Immune Non-responders With HIV-1 Infection[NCT01666990] | Phase 1/Phase 2 | 60 participants (Anticipated) | Interventional | 2012-06-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Average difference between 48-week and Baseline DAS28.~The Disease Activity Score for 28 Joints (DAS28) is a well-validated composite outcome measure ranging from 2-10 (higher scores indicating more disease) that incorporates a tender and swollen joint count of 28 joints, a laboratory measure of systemic inflammation (ESR) and a patient-reported general assessment of health on a visual analog scale (ranging from 0-10cm) all into one measure.~Low disease activity is defined as DAS28 ≤ 3.2 units." (NCT00405275)
Timeframe: 48 weeks after baseline assessment
| Intervention | units on a scale (Mean) |
|---|---|
| Triple | -2.12 |
| Etanercept | -2.29 |
6 reviews available for sulfasalazine and Cholera Infantum
| Article | Year |
|---|---|
[Gastrointestinal side effects in the therapy of rheumatologic diseases].
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antirheumatic | 2002 |
Sulfasalazine. Adverse effects and desensitization.
Topics: Anemia, Hemolytic; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Gastrointestinal D | 1983 |
Prostaglandins as factors in diseases of the alimentary tract.
Topics: Aminosalicylic Acids; Bacterial Toxins; Carcinoma; Colonic Neoplasms; Diarrhea; Gallbladder Diseases | 1976 |
The use of chloroquine and D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Captopril; Chloroquine; Clinical T | 1986 |
Drugs and the ageing gut, liver and pancreas.
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Animals; Antacids; Anti-Ulcer Agen | 1985 |
Cell-mediated immunity in gastrointestinal disease.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Antilymphocyte Serum; B-Lymphocytes; Celiac Diseas | 1986 |
7 trials available for sulfasalazine and Cholera Infantum
| Article | Year |
|---|---|
Rheumatoid arthritis triple therapy compared with etanercept: difference in infectious and gastrointestinal adverse events.
Topics: Abscess; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Etaner | 2017 |
Comparison of Tripterygium wilfordii Hook F versus sulfasalazine in the treatment of rheumatoid arthritis: a randomized trial.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; D | 2009 |
Comparison of Tripterygium wilfordii Hook F versus sulfasalazine in the treatment of rheumatoid arthritis: a randomized trial.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; D | 2009 |
Comparison of Tripterygium wilfordii Hook F versus sulfasalazine in the treatment of rheumatoid arthritis: a randomized trial.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; D | 2009 |
Comparison of Tripterygium wilfordii Hook F versus sulfasalazine in the treatment of rheumatoid arthritis: a randomized trial.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; D | 2009 |
Does gastrointestinal adverse drug reaction influence therapeutic effect in the treatment of rheumatoid arthritis?
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Diclofenac; Drug Therapy, Combination; Drugs, Chinese H | 2010 |
Tolerability of enteric-coated sulphasalazine in rheumatoid arthritis: results of a co-operating clinics study.
Topics: Arthritis, Rheumatoid; Central Nervous System Diseases; Drug Eruptions; Female; Gastrointestinal Dis | 1990 |
The use of chloroquine and D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Captopril; Chloroquine; Clinical T | 1986 |
Outcome of long-term treatment of rheumatoid arthritis with second-line agents.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Gastrointestinal Diseases | 1987 |
Sulfasalazine in the treatment of ankylosing spondylitis. A twenty-six-week, placebo-controlled clinical trial.
Topics: Analysis of Variance; Clinical Trials as Topic; Double-Blind Method; Drug Eruptions; Gastrointestina | 1988 |
14 other studies available for sulfasalazine and Cholera Infantum
| Article | Year |
|---|---|
A rare cause of oligoarthritis with septic presentation.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Reactive; Diarrhea; Dysuria; Fever; Gastr | 2018 |
The Chinese herbal remedy Tripterygium wilfordii Hook F in the treatment of rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; D | 2009 |
[Retrospective study of adverse events in patients with rheumatoid arthritis treated with second-line drugs].
Topics: Adult; Anorexia; Antirheumatic Agents; Arthritis, Rheumatoid; Exanthema; Female; Gastrointestinal Di | 2002 |
CONTROLLED TRIAL OF SULPHASALAZINE IN THE TREATMENT OF ULCERATIVE COLITIS.
Topics: Anemia; Anemia, Hemolytic; Biomedical Research; Colitis; Colitis, Ulcerative; Drug Therapy; Gastroin | 1964 |
[TREATMENT OF EXUDATIVE ENTEROPATHIES].
Topics: Drug Therapy; Gastrointestinal Diseases; Humans; Hypoproteinemia; Prednisone; Protein-Losing Enterop | 1965 |
Toxicity of sulphasalazine in rheumatoid arthritis. Possible protective effect of rheumatoid factors and corticosteroids.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Drug Eruptions; Female; Gas | 1993 |
Methotrexate and sulfasalazine combination therapy: is it worth the risk?
Topics: Aged; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; M | 1993 |
Prevalence of Helicobacter pylori infection and related upper gastrointestinal lesions in patients with inflammatory bowel diseases. A cross-sectional study with matching.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Colitis, Ulcerative; Crohn Disease; Cross-Sectional | 1997 |
[Salazopyridazine with vitamins A and D in gastrointestinal diseases in calves].
Topics: Animals; Cattle; Cattle Diseases; Drug Combinations; Drug Evaluation, Preclinical; Drug Therapy, Com | 1976 |
[A case of secondary amyloidosis which gastrointestinal symptoms improved by treatment with salazosulfapyridine].
Topics: Aged; Amyloidosis; Arthritis, Rheumatoid; Female; Gastrointestinal Diseases; Humans; Sulfasalazine | 1991 |
Acetylation, sulphasalazine and its effects.
Topics: Acetylation; Arthritis, Rheumatoid; Colitis, Ulcerative; Gastrointestinal Diseases; Humans; Sulfasal | 1987 |
The role of arachidonic acid metabolites in gastrointestinal homeostasis. Biochemical, histological and clinical gastrointestinal effects.
Topics: Animals; Colitis, Ulcerative; Diarrhea; Gastric Mucosa; Gastrointestinal Diseases; Homeostasis; Huma | 1987 |
Crohn's disease: a clinical study of 75 patients.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Child; Crohn Disease; Female; Fol | 1973 |
[Rectitis (rectosigmoiditis, rare rectocolitis hemorrhagica) in ambulant gastroenterologic metropolitan practice, 37 cases in about 10,000 first admissions].
Topics: Adult; Aged; Colitis; Colon, Sigmoid; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; | 1967 |