sulfasalazine has been researched along with Chemical and Drug Induced Liver Injury in 71 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Two patients presented severe febrile skin eruption following drug intake (carbamazepine or sulfazalazine), with hypereosinophilia and hepatitis." | 7.71 | [DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome after sulfasalazine and carmazepine: report of two cases]. ( Catteau, B; Delcey, V; Devulder, B; Fauchais, AL; Hachulla, E; Hatron, PY; Launay, D; Legout, L; Michon-Pasturel, U; Queyrel, V, 2001) |
| "A severe systemic reaction to sulfasalazine developed in a 21-year old female with rheumatoid arthritis characterized by eosinophilia, granulomatous enteritis and myelotoxicity, cholestatic hepatitis, and seizures." | 7.71 | Is it Crohn's disease? A severe systemic granulomatous reaction to sulfasalazine in patient with rheumatoid arthritis. ( Fontana, RJ; Greenson, J; Haftel, HM; Quallich, LG, 2001) |
| " Two patients presented severe febrile skin eruption following drug intake (carbamazepine or sulfazalazine), with hypereosinophilia and hepatitis." | 3.71 | [DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome after sulfasalazine and carmazepine: report of two cases]. ( Catteau, B; Delcey, V; Devulder, B; Fauchais, AL; Hachulla, E; Hatron, PY; Launay, D; Legout, L; Michon-Pasturel, U; Queyrel, V, 2001) |
| "A severe systemic reaction to sulfasalazine developed in a 21-year old female with rheumatoid arthritis characterized by eosinophilia, granulomatous enteritis and myelotoxicity, cholestatic hepatitis, and seizures." | 3.71 | Is it Crohn's disease? A severe systemic granulomatous reaction to sulfasalazine in patient with rheumatoid arthritis. ( Fontana, RJ; Greenson, J; Haftel, HM; Quallich, LG, 2001) |
| " An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | 1.36 | Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) |
| "Spontaneous reporting systems for adverse drug reactions (ADRs) are handicapped by under-reporting and limited detail on individual cases." | 1.35 | Hepatotoxicity associated with sulfasalazine in inflammatory arthritis: A case series from a local surveillance of serious adverse events. ( Amarasena, R; Bowman, S; Filer, A; Homer, D; Jobanputra, P; Jubb, R; Maggs, F; Rankin, E; Raza, K, 2008) |
| "5-aminosalicylates are extensively prescribed for the treatment of ulcerative colitis but have a wide range of described adverse effects." | 1.31 | Sulphasalazine and mesalazine: serious adverse reactions re-evaluated on the basis of suspected adverse reaction reports to the Committee on Safety of Medicines. ( Langman, MJ; Ransford, RA, 2002) |
| "The development of a toxic hepatitis and dermatitis prompted interruption of the drug." | 1.29 | Sulfasalazine-associated encephalopathy in a patient with Crohn's disease. ( Achten, E; Dewilde, D; Mast, A; Pauwels, W; Schoonjans, R; Van Den Abeele, G; Van Maele, V, 1993) |
| "The development of toxic hepatitis and dermatitis prompted interruption of the drug." | 1.29 | Sulfasalazine-associated encephalopathy in a patient with Crohn's disease. ( Achten, E; Dewilde, D; Mast, A; Pauwels, W; Schoonjans, R; Van den Abeele, G; Van Maele, V, 1993) |
| "Two 19 year old patients with juvenile chronic arthritis developed liver toxicity during treatment with sulphasalazine." | 1.28 | Sulphasalazine induced hepatitis in juvenile rheumatoid arthritis. ( Caspi, D; Fuchs, D; Yaron, M, 1992) |
| "The clinical pattern was similar to infectious mononucleosis including pharyngitis and lymphadenopathy but infection by Epstein Barr virus or cytomegalovirus has been ruled out by serological tests." | 1.27 | [Hepatitis and mononucleosis syndrome related to the ingestion of salazosulfapyridine]. ( Beaugrand, M; Ferrier, JP; Labadie, H, 1986) |
| " In both instances there was an interval of three weeks between receiving the drug for the first time and the onset of the toxic reaction." | 1.26 | Combined hepatotoxicity and neurotoxicity following sulphasalazine administration. ( Gibson, GE; Rowland, R; Smith, MD, 1982) |
| "We report a patient with ulcerative colitis in whom hepatic granulomatosis was associated with salicylazosulfapyridine (Azulfidine)." | 1.26 | Granulomatous hepatitis associated with salicylazosulfapyridine therapy. ( Callen, JP; Soderstrom, RM, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (49.30) | 18.7374 |
| 1990's | 11 (15.49) | 18.2507 |
| 2000's | 10 (14.08) | 29.6817 |
| 2010's | 13 (18.31) | 24.3611 |
| 2020's | 2 (2.82) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Greene, N | 1 |
| Fisk, L | 1 |
| Naven, RT | 1 |
| Note, RR | 1 |
| Patel, ML | 1 |
| Pelletier, DJ | 1 |
| Morgan, RE | 2 |
| Trauner, M | 1 |
| van Staden, CJ | 2 |
| Lee, PH | 1 |
| Ramachandran, B | 1 |
| Eschenberg, M | 1 |
| Afshari, CA | 2 |
| Qualls, CW | 1 |
| Lightfoot-Dunn, R | 1 |
| Hamadeh, HK | 2 |
| Ekins, S | 1 |
| Williams, AJ | 1 |
| Xu, JJ | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Li, YC | 1 |
| Shen, JD | 1 |
| Lu, SF | 1 |
| Zhu, LL | 1 |
| Wang, BY | 1 |
| Bai, M | 1 |
| Xu, EP | 1 |
| Capelletti, MM | 1 |
| Manceau, H | 1 |
| Puy, H | 1 |
| Peoc'h, K | 1 |
| Jeimy, S | 1 |
| McRae, K | 1 |
| Pattani, R | 1 |
| Gupta, R | 1 |
| Mehra, NK | 1 |
| Jain, NK | 1 |
| Lin, KM | 1 |
| Cheng, TT | 1 |
| Lin, JC | 1 |
| Chen, CJ | 1 |
| Jobanputra, P | 2 |
| Masuda, H | 1 |
| Takahashi, Y | 1 |
| Nishida, Y | 1 |
| Asai, S | 1 |
| Perdan-Pirkmajer, K | 1 |
| Hočevar, A | 1 |
| Rotar, Ž | 1 |
| Žibert, J | 1 |
| Marolt, VF | 1 |
| Gučev, F | 1 |
| Tomšič, M | 1 |
| Ransford, RA | 1 |
| Langman, MJ | 1 |
| Vanhoof, J | 1 |
| Landewe, S | 1 |
| Van Wijngaerden, E | 1 |
| Geusens, P | 1 |
| Fischetti, F | 1 |
| Gerloni, R | 1 |
| Bardelli, M | 1 |
| Carretta, R | 1 |
| Descloux, E | 1 |
| Argaud, L | 1 |
| Dumortier, J | 1 |
| Scoazec, JY | 1 |
| Boillot, O | 1 |
| Robert, D | 1 |
| Debarbieux, S | 1 |
| Deroo-Berger, MC | 1 |
| Grande, S | 1 |
| Najioullah, F | 1 |
| Kanitakis, J | 1 |
| Faure, M | 1 |
| Claudy, A | 1 |
| Kampmann, P | 1 |
| Højlyng, N | 1 |
| Pedersen, M | 1 |
| Amarasena, R | 1 |
| Maggs, F | 1 |
| Homer, D | 1 |
| Bowman, S | 1 |
| Rankin, E | 1 |
| Filer, A | 1 |
| Raza, K | 1 |
| Jubb, R | 1 |
| Namias, A | 1 |
| Bhalotra, R | 2 |
| Donowitz, M | 1 |
| Losek, JD | 1 |
| Werlin, SL | 1 |
| Smith, MD | 1 |
| Gibson, GE | 1 |
| Rowland, R | 1 |
| Lennard, TW | 1 |
| Farndon, JR | 1 |
| Taffet, SL | 1 |
| Das, KM | 1 |
| Holdsworth, CD | 1 |
| Pullar, T | 1 |
| Capell, HA | 1 |
| Fich, A | 1 |
| Schwartz, J | 1 |
| Braverman, D | 1 |
| Zifroni, A | 1 |
| Rachmilewitz, D | 1 |
| Schoonjans, R | 2 |
| Mast, A | 2 |
| Van Den Abeele, G | 2 |
| Dewilde, D | 2 |
| Achten, E | 2 |
| Van Maele, V | 2 |
| Pauwels, W | 2 |
| Pijls, H | 1 |
| Sentürk, T | 1 |
| Aydintuğ, AO | 1 |
| Düzgün, N | 1 |
| Tokgöz, G | 1 |
| Besnard, M | 1 |
| Debray, D | 1 |
| Durand, P | 1 |
| Cézard, JP | 1 |
| Navarro, J | 1 |
| Queyrel, V | 1 |
| Catteau, B | 1 |
| Michon-Pasturel, U | 1 |
| Fauchais, AL | 1 |
| Delcey, V | 1 |
| Launay, D | 1 |
| Legout, L | 1 |
| Hachulla, E | 1 |
| Hatron, PY | 1 |
| Devulder, B | 1 |
| Quallich, LG | 1 |
| Greenson, J | 1 |
| Haftel, HM | 1 |
| Fontana, RJ | 1 |
| Drayer, DE | 1 |
| Reidenberg, MM | 1 |
| Mihas, AA | 1 |
| Goldenberg, DJ | 1 |
| Slaughter, RL | 1 |
| Chester, AC | 1 |
| Diamond, LH | 1 |
| Schreiner, GE | 1 |
| Callen, JP | 1 |
| Soderstrom, RM | 1 |
| Blackstone, MO | 1 |
| Jacobs, E | 1 |
| Paulet, P | 1 |
| Rahier, J | 1 |
| Kanner, RS | 1 |
| Tedesco, FJ | 1 |
| Kalser, MH | 1 |
| Gulley, RM | 1 |
| Mirza, A | 1 |
| Kelly, CE | 1 |
| Sotolongo, RP | 1 |
| Neefe, LI | 1 |
| Rudzki, C | 1 |
| Ishak, KG | 1 |
| Vyse, T | 1 |
| So, AK | 1 |
| Caspi, D | 1 |
| Fuchs, D | 1 |
| Yaron, M | 1 |
| Marinos, G | 1 |
| Riley, J | 1 |
| Painter, DM | 1 |
| McCaughan, GW | 1 |
| Crowley, J | 1 |
| Situnayake, RD | 1 |
| Brooks, H | 1 |
| Taylor, HG | 1 |
| Nichol, FE | 1 |
| Loring, L | 1 |
| Massarelli, JJ | 1 |
| Challier, P | 1 |
| Granveau, C | 1 |
| Leroy, D | 1 |
| Fontaine, JL | 1 |
| Boyer, DL | 1 |
| Li, BU | 1 |
| Fyda, JN | 1 |
| Friedman, RA | 1 |
| Gyssens, IC | 1 |
| de Bock, RF | 1 |
| Peetermans, ME | 1 |
| Gremse, DA | 1 |
| Bancroft, J | 1 |
| Moyer, MS | 1 |
| Mulder, H | 1 |
| Gratama, S | 1 |
| Farr, M | 1 |
| Symmons, DP | 1 |
| Bacon, PA | 1 |
| Woodhouse, KW | 1 |
| Abadia, R | 1 |
| Jammet, P | 1 |
| Christoforov, B | 1 |
| Cremer, GA | 1 |
| Ribe, J | 1 |
| Benkov, KJ | 1 |
| Thung, SN | 1 |
| Shen, SC | 1 |
| LeLeiko, NS | 1 |
| Haines, JD | 1 |
| Labadie, H | 1 |
| Beaugrand, M | 1 |
| Ferrier, JP | 1 |
| Jennings, PE | 1 |
| Blandford, RL | 1 |
| Rosenthal, FD | 1 |
| Falguera Sacrest, M | 1 |
| de Celis Bernat, G | 1 |
| Pintó Sala, J | 1 |
| Baliellas Comellas, C | 1 |
| Poland, GA | 1 |
| Love, KR | 1 |
| MacGilchrist, AJ | 1 |
| Hunter, JA | 1 |
| Pinals, RS | 1 |
| Burke, DA | 1 |
| Manning, AP | 1 |
| Williamson, JM | 1 |
| Axon, AT | 1 |
| Rafoth, RJ | 1 |
9 reviews available for sulfasalazine and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
Ferroptosis in Liver Diseases: An Overview.
Topics: alpha-Tocopherol; Animals; Autophagy; Chemical and Drug Induced Liver Injury; Cyclohexylamines; Cyst | 2020 |
Sulfasalazine. Adverse effects and desensitization.
Topics: Anemia, Hemolytic; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Gastrointestinal D | 1983 |
Sulphasalazine: a 'new' antirheumatic drug.
Topics: Agranulocytosis; Anemia; Antibody Formation; Arthritis, Rheumatoid; Bile; Chemical and Drug Induced | 1984 |
Sulfasalazine-induced fulminant hepatic failure.
Topics: Adult; Chemical and Drug Induced Liver Injury; Colitis, Ulcerative; Female; Hepatic Encephalopathy; | 1992 |
Sulfasalazine-induced hepatotoxicity in children with inflammatory bowel disease.
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Female; Humans; Inflammatory Bowel Diseases; Sul | 1989 |
Drugs and the ageing gut, liver and pancreas.
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Animals; Antacids; Anti-Ulcer Agen | 1985 |
[Hepatotoxicity of drugs commonly used in rheumatology].
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Dextrop | 1985 |
Sulfasalazine in the rheumatic disease.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Central Nervous System; Chemical and Drug Induced Liver | 1988 |
1 trial available for sulfasalazine and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Sulfasalazine in the rheumatic disease.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Central Nervous System; Chemical and Drug Induced Liver | 1988 |
62 other studies available for sulfasalazine and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Transcriptomic analysis reveals the mechanism of sulfasalazine-induced liver injury in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Gene Expre | 2020 |
A 63-year-old returned traveller with fever, rash, hepatitis and eosinophilia.
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Live | 2018 |
Development and characterization of sulfasalazine loaded fucosylated PPI dendrimer for the treatment of cytokine-induced liver damage.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aziridines; Chemical and Drug Induced Liver Injury | 2014 |
Tumor necrosis factor-α antagonist therapy for concomitant rheumatoid arthritis and hepatitis C virus infection: a case series study.
Topics: Adalimumab; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumato | 2015 |
BSR DMARD monitoring guidelines: sulfasalazine.
Topics: Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Drug Monitoring; Humans; Practice Guid | 2008 |
Comparison of the effect of mesalazine and sulfasalazine on laboratory parameters: a retrospective observational study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Cohort Studi | 2012 |
Tumour necrosis factor-alpha inhibitor-induced hepatic injury in patients with rheumatoid arthritis: two case reports and an analysis of the laboratory data from the Slovenian national biologicals registry.
Topics: Adalimumab; Adult; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; B | 2013 |
Sulphasalazine and mesalazine: serious adverse reactions re-evaluated on the basis of suspected adverse reaction reports to the Committee on Safety of Medicines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Inju | 2002 |
High incidence of hepatotoxicity of isoniazid treatment for tuberculosis chemoprophylaxis in patients with rheumatoid arthritis treated with methotrexate or sulfasalazine and anti-tumour necrosis factor inhibitors.
Topics: Adult; Aged; Antirheumatic Agents; Antitubercular Agents; Arthritis, Rheumatoid; Chemical and Drug I | 2003 |
Abrupt occurrence of high fever and rash in a patient treated with sulphasalazine for psoriatic arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Psoriatic; Chemical and Drug Induced Liver Injur | 2003 |
Favourable issue of a fulminant hepatitis associated with sulfasalazine DRESS syndrome without liver transplantation.
Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Drug Eruptio | 2005 |
[Drug hypersensitivity syndrome associated with a primary HHV6 infection].
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Drug Eruption | 2006 |
[Life-threatening liver failure and severe dyscrasias in blood and lymph nodes caused by sulphasalazine].
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Cell Count; Chemical and Drug Induced Live | 2006 |
Hepatotoxicity associated with sulfasalazine in inflammatory arthritis: A case series from a local surveillance of serious adverse events.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, | 2008 |
Reversible sulfasalazine-induced granulomatous hepatitis.
Topics: Adult; Chemical and Drug Induced Liver Injury; Granuloma; Hepatitis; Humans; Liver Diseases; Male; S | 1981 |
Sulfasalazine hepatotoxicity.
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Humans; Liver; Male; Sulf | 1981 |
Combined hepatotoxicity and neurotoxicity following sulphasalazine administration.
Topics: Adult; Biopsy; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Diseases; Liver | 1982 |
Sulphasalazine hepatotoxicity after 15 years' successful treatment for ulcerative colitis.
Topics: Adult; Chemical and Drug Induced Liver Injury; Colitis, Ulcerative; Humans; Liver Function Tests; Ma | 1983 |
Sulphasalazine hepatotoxicity after 15 years' treatment.
Topics: Chemical and Drug Induced Liver Injury; Colitis, Ulcerative; Humans; Liver Function Tests; Sulfasala | 1983 |
Sulfasalazine hepatotoxicity.
Topics: Adult; Biopsy; Chemical and Drug Induced Liver Injury; Colitis, Ulcerative; Female; Humans; Liver Fu | 1984 |
Sulfasalazine-associated encephalopathy in a patient with Crohn's disease.
Topics: Acute Disease; Adult; Brain; Brain Diseases; Chemical and Drug Induced Liver Injury; Coma; Crohn Dis | 1993 |
Sulfasalazine-associated encephalopathy in a patient with Crohn's disease.
Topics: Adult; Brain Diseases; Chemical and Drug Induced Liver Injury; Crohn Disease; Drug Eruptions; Drug H | 1993 |
[A frequently used drug with fatal outcome!].
Topics: Animals; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Colitis; Dog Diseases; Dogs; | 1997 |
Seizures and hepatotoxicity following sulphasalazine administration.
Topics: Adult; Antirheumatic Agents; Arthritis; Chemical and Drug Induced Liver Injury; Chronic Disease; Fem | 1997 |
Sulfasalazine-induced fulminant hepatitis in pediatric Crohn's disease: report of two cases.
Topics: Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Child; Crohn Disease; Female; Huma | 1998 |
[DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome after sulfasalazine and carmazepine: report of two cases].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants | 2001 |
Is it Crohn's disease? A severe systemic granulomatous reaction to sulfasalazine in patient with rheumatoid arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Crohn Di | 2001 |
Clinical consequences of polymorphic acetylation of basic drugs.
Topics: Acetylation; Antibodies, Antinuclear; Biotransformation; Chemical and Drug Induced Liver Injury; Hum | 1977 |
Sulfasalazine toxic reactions. Hepatitis, fever, and skin rash with hypocomplementemia and immune complexes.
Topics: Adult; Antigen-Antibody Complex; Chemical and Drug Induced Liver Injury; Complement System Proteins; | 1978 |
Hypersensitivity to salicylazosulfapyridine: renal and hepatic toxic reactions.
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Eosinophilia; Female; Fever; H | 1978 |
Granulomatous hepatitis associated with salicylazosulfapyridine therapy.
Topics: Adult; Chemical and Drug Induced Liver Injury; Colitis, Ulcerative; Female; Granuloma; Humans; Sulfa | 1978 |
Hypersensitivity reaction to sulfasalazine--two reports of the same patient.
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Kidney Disease | 1978 |
Hypersensitivity reaction to sulfasalazine--another case.
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Sulfasalazine | 1978 |
Azulfidine- (sulfasalazine-) induced hepatic injury.
Topics: Adolescent; Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced | 1978 |
Hepatotoxicity of salicylazosulfapyridine: a case report and review of the literature.
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Sulfasalazine; | 1979 |
Hypersensitivity reaction to sulfasalazine with severe hepatotoxicity.
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Inflammatory B | 1978 |
Sulphasalazine induced autoimmune syndrome.
Topics: Adult; Arthritis, Rheumatoid; Autoimmune Diseases; Chemical and Drug Induced Liver Injury; Drug Erup | 1992 |
Sulphasalazine induced hepatitis in juvenile rheumatoid arthritis.
Topics: Adolescent; Adult; Alkaline Phosphatase; Arthritis, Juvenile; Chemical and Drug Induced Liver Injury | 1992 |
Sulphasalazine induced hepatitis in adult Still's disease.
Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Still's Disease, Adult-Onset; Sulfasa | 1992 |
The three week sulphasalazine syndrome.
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Humans; Male; Middle Aged; Prednisolo | 1992 |
A case of possible sulfasalazine neurotoxicity.
Topics: Aged; Chemical and Drug Induced Liver Injury; Humans; Male; Nervous System; Sulfasalazine | 1990 |
[Dermatitis and hepatitis in a child treated with salazosulfapyridine in hemorrhagic rectocolitis].
Topics: Chemical and Drug Induced Liver Injury; Child; Colitis, Ulcerative; Drug Eruptions; Humans; Male; Su | 1989 |
[Sulfasalazine allergy: fever, skin rash, hepatitis and T-lymphocytes].
Topics: Adult; Antigens, Differentiation, T-Lymphocyte; Chemical and Drug Induced Liver Injury; Drug Eruptio | 1989 |
Sulfasalazine hypersensitivity with hepatotoxicity, thrombocytopenia, and erythroid hypoplasia.
Topics: Anemia; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Child; Drug Hypersensitivity; | 1989 |
Azodisalicylate (Dipentum)-induced hepatitis?
Topics: Aged; Aminosalicylic Acids; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Diverticuli | 1989 |
Raised serum alkaline phosphatase and aspartate transaminase levels in two rheumatoid patients treated with sulphasalazine.
Topics: Aged; Alkaline Phosphatase; Arthritis, Rheumatoid; Aspartate Aminotransferases; Chemical and Drug In | 1985 |
Fatal massive hepatic necrosis: a probable hypersensitivity reaction to sulfasalazine.
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Colitis, Ulcerative; Drug Hypersensitivity; Huma | 1986 |
Hepatotoxicity after treatment with sulfasalazine.
Topics: Adult; Chemical and Drug Induced Liver Injury; Crohn Disease; Drug Eruptions; Drug Hypersensitivity; | 1986 |
[Hepatitis and mononucleosis syndrome related to the ingestion of salazosulfapyridine].
Topics: Adult; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Humans; Infectious Mononucle | 1986 |
Acute sulphasalazine hepatotoxicity.
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Humans; Male; Sulfasalazine | 1986 |
[Hepatitis caused by salicylazosulfapyridine].
Topics: Adult; Chemical and Drug Induced Liver Injury; Humans; Male; Sulfasalazine | 1986 |
Marked atypical lymphocytosis, hepatitis, and skin rash in sulfasalazine drug allergy.
Topics: Adult; Chemical and Drug Induced Liver Injury; Erythema; Humans; Lymphocytosis; Male; Sulfasalazine | 1986 |
Sulphasalazine hepatotoxicity: lack of a hypersensitivity response.
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Female; Humans; Middle Aged; Sulfasal | 1986 |
Adverse reactions to sulphasalazine and 5-amino salicylic acid in the same patient.
Topics: Adult; Aminosalicylic Acids; Chemical and Drug Induced Liver Injury; Humans; Male; Mesalamine; Sulfa | 1987 |
Systemic granulomatous reaction to salicylazosulfapyridine (Azulfidine) in a patient with Crohn's disease.
Topics: Adult; Biopsy; Chemical and Drug Induced Liver Injury; Crohn Disease; Diagnosis, Differential; Femal | 1974 |