sulfasalazine has been researched along with Carcinoma, Anaplastic in 6 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Incubation of the mammary cancer cells with SASP (0." | 5.34 | Sulfasalazine-induced reduction of glutathione levels in breast cancer cells: enhancement of growth-inhibitory activity of Doxorubicin. ( Buckley, AR; Buckley, DJ; Gout, PW; Narang, VS; Pauletti, GM, 2007) |
| "Incubation of the mammary cancer cells with SASP (0." | 1.34 | Sulfasalazine-induced reduction of glutathione levels in breast cancer cells: enhancement of growth-inhibitory activity of Doxorubicin. ( Buckley, AR; Buckley, DJ; Gout, PW; Narang, VS; Pauletti, GM, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Idei, U | 1 |
| Ohta, T | 1 |
| Yamatani, H | 1 |
| Seino, M | 1 |
| Nagase, S | 1 |
| Narang, VS | 1 |
| Pauletti, GM | 1 |
| Gout, PW | 1 |
| Buckley, DJ | 1 |
| Buckley, AR | 1 |
| Arlt, A | 1 |
| Vorndamm, J | 1 |
| Breitenbroich, M | 1 |
| Fölsch, UR | 1 |
| Kalthoff, H | 1 |
| Schmidt, WE | 1 |
| Schäfer, H | 1 |
| Bennett, A | 1 |
| Rogers, AI | 1 |
| Gillies, M | 1 |
| Skyring, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Study Evaluating the Efficacy and Safety of Sulfasalazine in Patients With Metastatic Colorectal Cancer[NCT06134388] | Phase 3 | 50 participants (Anticipated) | Interventional | 2023-09-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for sulfasalazine and Carcinoma, Anaplastic
| Article | Year |
|---|---|
Prostaglandins as factors in diseases of the alimentary tract.
Topics: Aminosalicylic Acids; Bacterial Toxins; Carcinoma; Colonic Neoplasms; Diarrhea; Gallbladder Diseases | 1976 |
5 other studies available for sulfasalazine and Carcinoma, Anaplastic
| Article | Year |
|---|---|
Mechanism of Cell Death by Combined Treatment with an xCT Inhibitor and Paclitaxel: An Alternative Therapeutic Strategy for Patients with Ovarian Clear Cell Carcinoma.
Topics: Carcinoma; Cell Death; Cell Line, Tumor; Glutathione; Humans; Paclitaxel; Reactive Oxygen Species; S | 2023 |
Sulfasalazine-induced reduction of glutathione levels in breast cancer cells: enhancement of growth-inhibitory activity of Doxorubicin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Antimetabolites, Antineoplasti | 2007 |
Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin.
Topics: Antineoplastic Agents; Carcinoma; DNA-Binding Proteins; Doxorubicin; Drug Resistance; Etoposide; Gli | 2001 |
Managing ulcerative colitis.
Topics: Azathioprine; Carcinoma; Colitis, Ulcerative; Colonic Neoplasms; Humans; Prednisone; Sulfasalazine | 1976 |
Ulcerative colitis: the experience of a Sydney teaching hospital.
Topics: Acute Disease; Adolescent; Adult; Australia; Bile Duct Neoplasms; Carcinoma; Child; Child, Preschool | 1970 |