sulfasalazine has been researched along with Cancer of Prostate in 4 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Events included eight patients with malignancies, two with pancytopenia taking methotrexate, three with septic arthritis, and two with septicaemias." | 3.71 | Monitoring and assessing the safety of disease-modifying antirheumatic drugs: a West Midlands experience. ( Bevan, J; Homer, D; Jobanputra, P; Maggs, F, 2002) |
| "Finally, BALB/c nude mice bearing prostate cancer xenografts were used to assess the anti-cancer effects of single or combined VC and SAS therapies." | 1.56 | The X ( Li, Z; Long, Y; Luo, G; Shen, W; Shi, X; Zhang, X; Zheng, Z, 2020) |
| "Here we examined advanced human prostate cancer cell lines, DU-145 and PC-3, for dependence on extracellular cystine and sensitivity to sulfasalazine (SASP), a potent inhibitor of the x(c)(-) cystine transporter." | 1.34 | Sulfasalazine-induced cystine starvation: potential use for prostate cancer therapy. ( Buckley, AR; Cunha, GR; Cutz, JC; Doxsee, DW; Gout, PW; Karp, CM; Kurita, T; Lo, M; Wang, Y; Wang, YZ; Xue, H, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, Z | 1 |
| Luo, G | 1 |
| Shi, X | 1 |
| Long, Y | 1 |
| Shen, W | 1 |
| Li, Z | 1 |
| Zhang, X | 1 |
| Hammami, MB | 1 |
| Mahadevan, U | 1 |
| Jobanputra, P | 1 |
| Maggs, F | 1 |
| Homer, D | 1 |
| Bevan, J | 1 |
| Doxsee, DW | 1 |
| Gout, PW | 1 |
| Kurita, T | 1 |
| Lo, M | 1 |
| Buckley, AR | 1 |
| Wang, Y | 1 |
| Xue, H | 1 |
| Karp, CM | 1 |
| Cutz, JC | 1 |
| Cunha, GR | 1 |
| Wang, YZ | 1 |
1 review available for sulfasalazine and Cancer of Prostate
| Article | Year |
|---|---|
Men With Inflammatory Bowel Disease: Sexual Function, Fertility, Medication Safety, and Prostate Cancer.
Topics: Depression; Gastrointestinal Agents; Humans; Infertility, Male; Inflammatory Bowel Diseases; Male; M | 2020 |
3 other studies available for sulfasalazine and Cancer of Prostate
| Article | Year |
|---|---|
The X
Topics: Acetylcysteine; Amino Acid Transport System y+; Animals; Antineoplastic Combined Chemotherapy Protoc | 2020 |
Monitoring and assessing the safety of disease-modifying antirheumatic drugs: a West Midlands experience.
Topics: Antirheumatic Agents; Arthritis, Infectious; Azathioprine; Drug Monitoring; Humans; Hypokalemia; Lun | 2002 |
Sulfasalazine-induced cystine starvation: potential use for prostate cancer therapy.
Topics: Amino Acid Transport System ASC; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Ag | 2007 |