sulfasalazine has been researched along with Cancer of Intestines in 8 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Crohn's disease is a perplexing disease with a high rate of morbidity and complications." | 2.35 | The protean manifestations of Crohn's disease. ( Farmer, RG, 1975) |
| "It is important to distinguish between ulcerative colitis and Crohn's colitis because response to treatment and prognosis are different." | 2.35 | Inflammatory disease of the colon: ulcerative colitis and Crohn's colitis. ( Ament, ME, 1975) |
| " To directly evaluate the ability of 5-ASA to suppress intestinal tumors, we studied several formulations of 5-ASA (free acid, sulfasalazine, and Pentasa) at multiple oral dosage levels [500, 2400, 4800, and 9600 parts/million (ppm)] in the adenomatous polyposis coli (Apc) mouse model of multiple intestinal neoplasia (Min)." | 1.30 | Evaluation of 5-aminosalicylic acid (5-ASA) for cancer chemoprevention: lack of efficacy against nascent adenomatous polyps in the Apc(Min) mouse. ( Gendler, SJ; Hirsch, RE; Leighton, JA; Morrow, JD; Ritland, SR; Weaver, AL, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Janowitz, HD | 1 |
| Sachar, DB | 1 |
| Rampton, DS | 1 |
| Hawkey, CJ | 1 |
| Ritland, SR | 1 |
| Leighton, JA | 1 |
| Hirsch, RE | 1 |
| Morrow, JD | 1 |
| Weaver, AL | 1 |
| Gendler, SJ | 1 |
| Farmer, RG | 1 |
| Ament, ME | 1 |
| Daum, F | 1 |
| Boley, SJ | 1 |
| Cohen, MI | 1 |
| Saeed, W | 1 |
| Kim, S | 1 |
| Burch, BH | 1 |
| Greenberger, NJ | 1 |
| Saegh, S | 1 |
| Ruppert, RD | 1 |
5 reviews available for sulfasalazine and Cancer of Intestines
| Article | Year |
|---|---|
Inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Adult; Child; Colectomy; Colitis, Ulcerative; Crohn Disease; Female; Humans | 1982 |
Prostaglandins and ulcerative colitis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Colitis, Ulcerative; Cyclooxygenase Inhibitors; Dogs; | 1984 |
The protean manifestations of Crohn's disease.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Arthritis; Azathioprine; Child; Colectomy; Colitis, | 1975 |
Inflammatory disease of the colon: ulcerative colitis and Crohn's colitis.
Topics: Adrenal Cortex Hormones; Adult; Anus Diseases; Arthritis; Azathioprine; Child, Preschool; Colectomy; | 1975 |
Inflammatory bowel disease in the adolescent patient.
Topics: Adolescent; Adrenal Cortex Hormones; Animals; Colitis, Ulcerative; Colonic Diseases; Crohn Disease; | 1973 |
3 other studies available for sulfasalazine and Cancer of Intestines
| Article | Year |
|---|---|
Evaluation of 5-aminosalicylic acid (5-ASA) for cancer chemoprevention: lack of efficacy against nascent adenomatous polyps in the Apc(Min) mouse.
Topics: Adenomatous Polyps; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Chemo | 1999 |
Development of carcinoma in regional enteritis.
Topics: Adenocarcinoma, Mucinous; Barium Sulfate; Cecum; Colon; Colonic Diseases; Crohn Disease; Enema; Fluo | 1974 |
Urine indican excretion in malabsorptive disorders.
Topics: Celiac Disease; Crohn Disease; Diagnosis, Differential; Feces; Humans; Indican; Intestinal Absorptio | 1968 |