sulfasalazine has been researched along with Brain Ischemia in 3 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Management of cerebral ischemia/reperfusion (I/R) injury is still difficult process today." | 1.46 | Effects of Sulphasalazine in Cerebral Ischemia Reperfusion Injury in Rat. ( Bakar, B; Cetin, C; Dincel, GC; Erdogan, AM; Kisa, U, 2017) |
| "Neu2000 protected against the effects of middle cerebral artery occlusion, even when delivered 8 h after reperfusion." | 1.34 | Marked prevention of ischemic brain injury by Neu2000, an NMDA antagonist and antioxidant derived from aspirin and sulfasalazine. ( Ahn, YM; Byun, HY; Cho, JY; Cho, SI; Chung, JM; Gwag, BJ; Im, DS; Kim, KW; Ko, SY; Kwon, HJ; Lee, HU; Lee, JY; Lee, MJ; Lee, YA; Lim, HR; Moon, HS; Noh, JH; Park, SM; Son, SJ; Won, SJ; Yoon, SH; Yun, BS, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Khellaf, L | 1 |
| Cosserat, J | 1 |
| Calas, A | 1 |
| Brasme, H | 1 |
| Charles, P | 1 |
| Cetin, C | 1 |
| Erdogan, AM | 1 |
| Dincel, GC | 1 |
| Bakar, B | 1 |
| Kisa, U | 1 |
| Gwag, BJ | 1 |
| Lee, YA | 1 |
| Ko, SY | 1 |
| Lee, MJ | 1 |
| Im, DS | 1 |
| Yun, BS | 1 |
| Lim, HR | 1 |
| Park, SM | 1 |
| Byun, HY | 1 |
| Son, SJ | 1 |
| Kwon, HJ | 1 |
| Lee, JY | 1 |
| Cho, JY | 1 |
| Won, SJ | 1 |
| Kim, KW | 1 |
| Ahn, YM | 1 |
| Moon, HS | 1 |
| Lee, HU | 1 |
| Yoon, SH | 1 |
| Noh, JH | 1 |
| Chung, JM | 1 |
| Cho, SI | 1 |
3 other studies available for sulfasalazine and Brain Ischemia
| Article | Year |
|---|---|
Unusual neurological and cardiac complications of drug reaction with eosinophilia and systemic symptoms syndrome: a case report.
Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents, Non-Steroidal; Brain Ischemia; Drug Hyperse | 2021 |
Effects of Sulphasalazine in Cerebral Ischemia Reperfusion Injury in Rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Edema; Brain Ischemia; Cerebral Cortex; Hipp | 2017 |
Marked prevention of ischemic brain injury by Neu2000, an NMDA antagonist and antioxidant derived from aspirin and sulfasalazine.
Topics: Animals; Antioxidants; Aspirin; Benzoates; Brain Ischemia; Cells, Cultured; Excitatory Amino Acid An | 2007 |