sulfasalazine has been researched along with Brain Inflammation in 2 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of seizures with acute encephalopathy in a female patient under sulfasalazine treatment for polyarthritis." | 3.71 | [Sulfasalazine neurotoxicity]. ( Chadenat, ML; Dechy, H; Dorra, M; Dupont, C; Morelon, S; Raffin-Sanson, ML; Rouveix, E, 2001) |
| " We examined the possibility that concurrent blockade of free radicals and prostaglandin E(2) (PGE(2))-mediated inflammation might constitute a safe and effective therapeutic approach to ALS." | 1.38 | Concurrent blockade of free radical and microsomal prostaglandin E synthase-1-mediated PGE2 production improves safety and efficacy in a mouse model of amyotrophic lateral sclerosis. ( Cho, W; Gwag, BJ; Im, DS; Lee, JH; Lee, JK; Lee, YA; Lee, YB; Shin, JH; Springer, JE; Yun, BS, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shin, JH | 1 |
| Lee, YA | 1 |
| Lee, JK | 1 |
| Lee, YB | 1 |
| Cho, W | 1 |
| Im, DS | 1 |
| Lee, JH | 1 |
| Yun, BS | 1 |
| Springer, JE | 1 |
| Gwag, BJ | 1 |
| Chadenat, ML | 1 |
| Morelon, S | 1 |
| Dupont, C | 1 |
| Dechy, H | 1 |
| Raffin-Sanson, ML | 1 |
| Dorra, M | 1 |
| Rouveix, E | 1 |
2 other studies available for sulfasalazine and Brain Inflammation
| Article | Year |
|---|---|
Concurrent blockade of free radical and microsomal prostaglandin E synthase-1-mediated PGE2 production improves safety and efficacy in a mouse model of amyotrophic lateral sclerosis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Anti-Infl | 2012 |
[Sulfasalazine neurotoxicity].
Topics: Acute Disease; Adult; Antirheumatic Agents; Arthritis; Encephalitis; Epilepsy; Female; Humans; Sulfa | 2001 |