sulfasalazine has been researched along with Body Weight in 34 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The ameliorating effect of the azo conjugate and therapeutic efficacy of the carrier system was evaluated in trinitrobenzenesulfonic acid-induced experimental colitis model." | 7.74 | Colon-specific, mutual azo prodrug of 5-aminosalicylic acid with L-tryptophan: synthesis, kinetic studies and evaluation of its mitigating effect in trinitrobenzenesulfonic acid-induced colitis in rats. ( Bhatt, L; Dhaneshwar, SS; Gairola, N; Kandpal, M; Vadnerkar, G, 2007) |
| "Alendronate treatment (25 or 75 mg kg(-1) day(-1)) resulted in a decrease in the colonic damage score and loss of body weight (at 25 mg kg(-1) day(-1) only)." | 7.74 | The bisphosphonate alendronate improves the damage associated with trinitrobenzenesulfonic acid-induced colitis in rats. ( Ballester, I; Daddaoua, A; López-Posadas, R; Martínez-Augustin, O; Nieto, A; Sánchez de Medina, F; Suárez, MD; Zarzuelo, A, 2007) |
| "The anti-inflammatory effect of three flavonoids from the root of Scutellaria baicalensis (baicalein, baicalin and wogonin) was evaluated in a murine model of acute experimental colitis induced by dextran sulfate sodium (DSS)." | 7.71 | Evaluation of the anti-inflammatory effect of baicalein on dextran sulfate sodium-induced colitis in mice. ( Cho, S; Cyong, JC; Hong, T; Jin, GB, 2002) |
| "Treatment with ectoine ameliorated the inflammatory changes in TNBS-induced colitis." | 5.39 | Novel effects of ectoine, a bacteria-derived natural tetrahydropyrimidine, in experimental colitis. ( Abdallah, DM; Abdel-Aziz, H; Khayyal, MT; Lentzen, G; Wadie, W, 2013) |
| "), which reduced mortality and pathology (including colon obstruction, ulceration, wall thickness, and myeloperoxidase release) more effectively than the clinically used drug sulfasalazine (100 mg/kg/day p." | 3.78 | Antagonism of protease-activated receptor 2 protects against experimental colitis. ( Cotterell, AJ; Do, AT; Fairlie, DP; Liu, L; Lohman, RJ; Suen, J; Vesey, DA, 2012) |
| " The ameliorating effect of the azo conjugate and therapeutic efficacy of the carrier system was evaluated in trinitrobenzenesulfonic acid-induced experimental colitis model." | 3.74 | Colon-specific, mutual azo prodrug of 5-aminosalicylic acid with L-tryptophan: synthesis, kinetic studies and evaluation of its mitigating effect in trinitrobenzenesulfonic acid-induced colitis in rats. ( Bhatt, L; Dhaneshwar, SS; Gairola, N; Kandpal, M; Vadnerkar, G, 2007) |
| "Alendronate treatment (25 or 75 mg kg(-1) day(-1)) resulted in a decrease in the colonic damage score and loss of body weight (at 25 mg kg(-1) day(-1) only)." | 3.74 | The bisphosphonate alendronate improves the damage associated with trinitrobenzenesulfonic acid-induced colitis in rats. ( Ballester, I; Daddaoua, A; López-Posadas, R; Martínez-Augustin, O; Nieto, A; Sánchez de Medina, F; Suárez, MD; Zarzuelo, A, 2007) |
| "The anti-inflammatory effect of three flavonoids from the root of Scutellaria baicalensis (baicalein, baicalin and wogonin) was evaluated in a murine model of acute experimental colitis induced by dextran sulfate sodium (DSS)." | 3.71 | Evaluation of the anti-inflammatory effect of baicalein on dextran sulfate sodium-induced colitis in mice. ( Cho, S; Cyong, JC; Hong, T; Jin, GB, 2002) |
| "Ulcerative colitis is a chronic inflammatory disease of the colon where leukotrienes are suggested to play an important role for keeping inflammation active." | 2.68 | Effects of Boswellia serrata gum resin in patients with ulcerative colitis. ( Ammon, HP; Gupta, I; Lüdtke, R; Malhotra, P; Parihar, A; Safayhi, H; Singh, GB, 1997) |
| "26 children with acute symptoms of Crohn's disease were treated with steroids and sulfasalazine (group A, 9 patients), with an elementary diet and sulfasalazine (group B, 10 patients), or with an elementary diet together with steroids and sulfasalazine (group C, 7 patients)." | 2.65 | [Basic diet in Crohn's disease]. ( Nützenadel, W; Stober, B; Ullrich, F, 1983) |
| "The property of anti-ulcerative colitis (anti-UC) was assessed at the levels of both in vitro and in vivo, with X-box-binding protein 1 (XBP1) being targeted in vitro." | 1.48 | Syntheses and structure-activity relationships on antibacterial and anti-ulcerative colitis properties of quaternary 13-substituted palmatines and 8-oxo-13-substituted dihydropalmatines. ( Deng, AJ; Li, J; Li, X; Li, ZH; Qin, HL; Song, L; Wang, SQ; Wu, LQ; Zhang, HJ; Zhang, ZH, 2018) |
| "Ulcerative colitis affects the colon by causing chronic inflammation on the mucosa." | 1.46 | Mucoadhesive chitosan hydrogels as rectal drug delivery vessels to treat ulcerative colitis. ( Barralet, J; Cerruti, M; Lerouge, S; Samaei, S; Stevenson, MM; Tam, M; Xu, J, 2017) |
| "Treatment with ectoine ameliorated the inflammatory changes in TNBS-induced colitis." | 1.39 | Novel effects of ectoine, a bacteria-derived natural tetrahydropyrimidine, in experimental colitis. ( Abdallah, DM; Abdel-Aziz, H; Khayyal, MT; Lentzen, G; Wadie, W, 2013) |
| "Sulfasalazine treatment also increased inosine levels in sciatic nerves of diabetic rats." | 1.35 | Sulfasalazine blocks the development of tactile allodynia in diabetic rats. ( Berti-Mattera, LN; Kern, TS; Mitchell, R; Nemet, I; Siegel, RE, 2008) |
| "Spontaneous colitis and colon cancer in the cotton-top tamarin have been shown to resemble human ulcerative colitis and its associated cancer." | 1.29 | A prospective study of the epidemiology of colitis and colon cancer in cotton-top tamarins (Saguinus oedipus). ( Ausman, LM; Johnson, LD; King, NW; Sehgal, PK, 1996) |
| " Four chemicals, using three different routes of exposure (in utero [accomplished by feeding the dam dosed feed], dosed feed, and gavage) were used to 1) evaluate the effect of diet restriction on the sensitivity of the bioassay toward chemically-induced chronic toxicity and carcinogenicity; and 2) evaluate the effect of weight-matched control groups on the sensitivity of the bioassays." | 1.29 | The sensitivity of the NTP bioassay for carcinogen hazard evaluation can be modulated by dietary restriction. ( Abdo, KM; Kari, FW, 1996) |
| "At the end of treatment, body weights were reduced in higher dose groups of sulfasalazine, CH 74A and sulfapyridine compared to control animals." | 1.27 | Effect of sulfasalazine and its analogs on fertility in male rats. ( Agback, H; Bardin, CW; Didolkar, AK; Johansson, ED; Keizer-Zucker, A; Sundaram, K, 1988) |
| "Ileocolitis was the most (52%) and colitis the least (9%) common form of disease with diffuse small bowel or ileal disease each comprising nearly 20% of the study group." | 1.26 | Prognosis in children with Crohn's disease. ( Gryboski, JD; Spiro, HM, 1978) |
| "Recurrences were more frequent in patients under than over 31 years of age at their first operation." | 1.26 | [Crohn's disease: course and prognosis in 169 patients (author's transl)]. ( Classen, M; Mörl, M; Zöberlein, HG, 1978) |
| "The growth of 37 children with ulcerative colitis have been analyzed." | 1.25 | Growth retardation in children with ulcerative colitis: the effect of medical and surgical therapy. ( Berger, M; Gribetz, D; Korelitz, BI, 1975) |
| " Salazopyrin is variably and comparatively poorly absorbed in man." | 1.23 | Salicylazosulfapyridine (salazopyrin or azopyrin) in rheumatoid arthritis and experimental polyarthritis. ( GARDNER, GM; KUZELL, WC, 1950) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (38.24) | 18.7374 |
| 1990's | 6 (17.65) | 18.2507 |
| 2000's | 6 (17.65) | 29.6817 |
| 2010's | 9 (26.47) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dhaneshwar, SS | 1 |
| Gairola, N | 1 |
| Kandpal, M | 1 |
| Vadnerkar, G | 1 |
| Bhatt, L | 1 |
| Song, L | 1 |
| Zhang, HJ | 1 |
| Deng, AJ | 1 |
| Li, J | 2 |
| Li, X | 1 |
| Li, ZH | 1 |
| Zhang, ZH | 1 |
| Wu, LQ | 1 |
| Wang, SQ | 1 |
| Qin, HL | 1 |
| Abdel-Aziz, H | 1 |
| Wadie, W | 1 |
| Abdallah, DM | 2 |
| Lentzen, G | 1 |
| Khayyal, MT | 1 |
| Yang, Y | 1 |
| He, J | 1 |
| Suo, Y | 1 |
| Lv, L | 1 |
| Wang, J | 1 |
| Huo, C | 1 |
| Zheng, Z | 1 |
| Wang, Z | 1 |
| Sun, W | 1 |
| Zhang, Y | 1 |
| Xu, J | 1 |
| Tam, M | 1 |
| Samaei, S | 1 |
| Lerouge, S | 1 |
| Barralet, J | 1 |
| Stevenson, MM | 1 |
| Cerruti, M | 1 |
| Xu, B | 1 |
| Li, YL | 1 |
| Xu, M | 1 |
| Yu, CC | 1 |
| Lian, MQ | 1 |
| Tang, ZY | 1 |
| Li, CX | 1 |
| Lin, Y | 1 |
| Berti-Mattera, LN | 1 |
| Kern, TS | 1 |
| Siegel, RE | 1 |
| Nemet, I | 1 |
| Mitchell, R | 1 |
| Cho, JY | 1 |
| Chi, SG | 1 |
| Chun, HS | 1 |
| Jiang, GL | 1 |
| Im, WB | 1 |
| Donde, Y | 1 |
| Wheeler, LA | 1 |
| Lohman, RJ | 1 |
| Cotterell, AJ | 1 |
| Suen, J | 1 |
| Liu, L | 1 |
| Do, AT | 1 |
| Vesey, DA | 1 |
| Fairlie, DP | 1 |
| Ismael, NR | 1 |
| Weber, MP | 1 |
| Martin, LJ | 1 |
| Biourge, VC | 1 |
| Nguyen, PG | 1 |
| Dumon, HJ | 1 |
| KUZELL, WC | 1 |
| GARDNER, GM | 1 |
| Ballester, I | 1 |
| Daddaoua, A | 1 |
| López-Posadas, R | 1 |
| Nieto, A | 1 |
| Suárez, MD | 1 |
| Zarzuelo, A | 1 |
| Martínez-Augustin, O | 1 |
| Sánchez de Medina, F | 1 |
| Navarro, J | 1 |
| Vargas, J | 1 |
| Cezard, JP | 1 |
| Charritat, JL | 1 |
| Polonovski, C | 1 |
| Stober, B | 1 |
| Nützenadel, W | 1 |
| Ullrich, F | 1 |
| Schade, RR | 1 |
| Van Thiel, DH | 1 |
| Gavaler, JS | 1 |
| Johnson, LD | 1 |
| Ausman, LM | 1 |
| Sehgal, PK | 1 |
| King, NW | 1 |
| Abdo, KM | 1 |
| Kari, FW | 1 |
| Gupta, I | 1 |
| Parihar, A | 1 |
| Malhotra, P | 1 |
| Singh, GB | 1 |
| Lüdtke, R | 1 |
| Safayhi, H | 1 |
| Ammon, HP | 1 |
| Aiko, S | 1 |
| Fuseler, J | 1 |
| Grisham, MB | 1 |
| Zhou, H | 1 |
| Mineshita, S | 1 |
| Hedin, A | 1 |
| Ehrsson, H | 1 |
| Eksborg, S | 1 |
| Finkel, Y | 1 |
| Hildebrand, H | 1 |
| Lidehäll, AK | 1 |
| Hong, T | 1 |
| Jin, GB | 1 |
| Cho, S | 1 |
| Cyong, JC | 1 |
| Tenore, A | 1 |
| Berman, WF | 1 |
| Parks, JS | 1 |
| Bongiovanni, AM | 1 |
| Henrikson, B | 1 |
| Hultén, L | 1 |
| Filipson, S | 1 |
| Sillĕn, U | 1 |
| Gryboski, JD | 1 |
| Spiro, HM | 1 |
| Mörl, M | 1 |
| Zöberlein, HG | 1 |
| Classen, M | 1 |
| Berger, M | 1 |
| Gribetz, D | 1 |
| Korelitz, BI | 1 |
| Didolkar, AK | 1 |
| Keizer-Zucker, A | 1 |
| Sundaram, K | 1 |
| Bardin, CW | 1 |
| Agback, H | 1 |
| Johansson, ED | 1 |
| Donald, JW | 1 |
| Donald, JG | 1 |
| Anthonisen, P | 1 |
| Barany, F | 1 |
| Folkenborg, O | 1 |
| Holtz, A | 1 |
| Jarnum, S | 1 |
| Kristensen, M | 1 |
| Riis, P | 1 |
| Walan, A | 1 |
| Worning, H | 1 |
3 trials available for sulfasalazine and Body Weight
| Article | Year |
|---|---|
[Basic diet in Crohn's disease].
Topics: Adolescent; Adrenal Cortex Hormones; Blood Proteins; Blood Sedimentation; Body Weight; Child; Crohn | 1983 |
Effects of Boswellia serrata gum resin in patients with ulcerative colitis.
Topics: Abdominal Pain; Adolescent; Adult; Biopsy; Blood Proteins; Body Weight; Calcium; Child; Colitis, Ulc | 1997 |
The clinical effect of salazosulphapyridine (Salazopyrin r) in Crohn's disease. A controlled double-blind study.
Topics: Adolescent; Adult; Aged; Blood Sedimentation; Body Weight; Clinical Trials as Topic; Crohn Disease; | 1974 |
31 other studies available for sulfasalazine and Body Weight
| Article | Year |
|---|---|
Colon-specific, mutual azo prodrug of 5-aminosalicylic acid with L-tryptophan: synthesis, kinetic studies and evaluation of its mitigating effect in trinitrobenzenesulfonic acid-induced colitis in rats.
Topics: Animals; Azo Compounds; Body Weight; Colitis; Kinetics; Mesalamine; Molecular Structure; Organ Size; | 2007 |
Syntheses and structure-activity relationships on antibacterial and anti-ulcerative colitis properties of quaternary 13-substituted palmatines and 8-oxo-13-substituted dihydropalmatines.
Topics: Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Berberine Alkaloids; Body Weight; Candida albican | 2018 |
Novel effects of ectoine, a bacteria-derived natural tetrahydropyrimidine, in experimental colitis.
Topics: Amino Acids, Diamino; Animals; Body Weight; Colitis; Colon; Dinoprostone; Disease Models, Animal; Do | 2013 |
Anti-inflammatory effect of taurocholate on TNBS-induced ulcerative colitis in mice.
Topics: Animals; Anti-Inflammatory Agents; Body Weight; Colitis, Ulcerative; Colon; Interferon-gamma; Interl | 2016 |
Mucoadhesive chitosan hydrogels as rectal drug delivery vessels to treat ulcerative colitis.
Topics: Adhesives; Animals; Body Weight; Catechols; Chitosan; Colitis, Ulcerative; Colon; Dose-Response Rela | 2017 |
Geniposide ameliorates TNBS-induced experimental colitis in rats via reducing inflammatory cytokine release and restoring impaired intestinal barrier function.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Caco-2 Cells; Colitis, Ulcerative; Cy | 2017 |
Sulfasalazine blocks the development of tactile allodynia in diabetic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; Chromatography, High P | 2008 |
Oral administration of docosahexaenoic acid attenuates colitis induced by dextran sulfate sodium in mice.
Topics: Acute-Phase Proteins; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body W | 2011 |
Comparison of prostaglandin E2 receptor subtype 4 agonist and sulfasalazine in mouse colitis prevention and treatment.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cell Proliferation; Colitis; Colon; D | 2010 |
Antagonism of protease-activated receptor 2 protects against experimental colitis.
Topics: Animals; Body Weight; Calcium Signaling; Colitis; Colon; Cytokines; Edema; HT29 Cells; Humans; Inden | 2012 |
Resveratrol abrogates adhesion molecules and protects against TNBS-induced ulcerative colitis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cell Adhesion Molecules; Colitis, Ulc | 2011 |
Influence of age and body size on orocecal transit time as assessed by use of the sulfasalazine method in healthy dogs.
Topics: Age Factors; Animal Feed; Animals; Body Weight; Dogs; Feces; Female; Gastrointestinal Agents; Gastro | 2003 |
Salicylazosulfapyridine (salazopyrin or azopyrin) in rheumatoid arthritis and experimental polyarthritis.
Topics: Animals; Arthritis; Arthritis, Rheumatoid; Body Weight; Erythrocyte Count; Gold; Humans; Joints; Leu | 1950 |
The bisphosphonate alendronate improves the damage associated with trinitrobenzenesulfonic acid-induced colitis in rats.
Topics: Administration, Oral; Alendronate; Animals; Anti-Inflammatory Agents; Body Weight; Bone Density Cons | 2007 |
Prolonged constant rate elemental enteral nutrition in Crohn's disease.
Topics: Adolescent; Body Height; Body Weight; Cecum; Child; Crohn Disease; Enteral Nutrition; Female; Food, | 1982 |
Chronic idiopathic ulcerative colitis. Pregnancy and fetal outcome.
Topics: Adolescent; Adult; Apgar Score; Body Weight; Colitis, Ulcerative; Female; Fetal Growth Retardation; | 1984 |
A prospective study of the epidemiology of colitis and colon cancer in cotton-top tamarins (Saguinus oedipus).
Topics: Adenocarcinoma; Animals; Body Weight; Campylobacter Infections; Colitis; Colonic Neoplasms; Disease | 1996 |
The sensitivity of the NTP bioassay for carcinogen hazard evaluation can be modulated by dietary restriction.
Topics: Animals; Body Weight; Carcinogenicity Tests; Dose-Response Relationship, Drug; Eating; Female; Food | 1996 |
Reproductive toxicology. Salicylazosulfapyridine.
Topics: Animals; Birth Weight; Body Weight; Dose-Response Relationship, Drug; Female; Fetal Death; Gastroint | 1997 |
Effects of nitric oxide synthase inhibition or sulfasalazine on the spontaneous colitis observed in HLA-B27 transgenic rats.
Topics: Animals; Animals, Genetically Modified; Body Weight; Colitis; Colon; Enzyme Inhibitors; HLA-B27 Anti | 1998 |
The effect of Oren-gedoku-to on experimental colitis in rats.
Topics: Animals; Anti-Ulcer Agents; Body Weight; Colitis; Drugs, Chinese Herbal; Gastrointestinal Agents; Ma | 1999 |
[A study of 5-ASA use among young patients with Crohn disease. Regular drug revision is of significance for all children with chronic disease].
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Child; Crohn Disease; Dose-Respons | 2001 |
Evaluation of the anti-inflammatory effect of baicalein on dextran sulfate sodium-induced colitis in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Colitis; Dextran Sulfate; Female; Fla | 2002 |
Basal and stimulated serum growth hormone concentrations in inflammatory bowel disease.
Topics: Adolescent; Animals; Body Height; Body Weight; Child; Colitis, Ulcerative; Crohn Disease; Female; Gl | 1977 |
Long-term study of the effect of treatment for ulcerative colitis.
Topics: Adolescent; Body Weight; Child; Colitis, Ulcerative; Colon; Cortisone; Female; Humans; Male; Proctit | 1978 |
Prognosis in children with Crohn's disease.
Topics: Adolescent; Adult; Body Height; Body Weight; Child; Child, Preschool; Colitis; Crohn Disease; Female | 1978 |
[Crohn's disease: course and prognosis in 169 patients (author's transl)].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Body Weight; Child; Child, Preschool; | 1978 |
Growth retardation in children with ulcerative colitis: the effect of medical and surgical therapy.
Topics: Adolescent; Body Weight; Child; Child, Preschool; Colectomy; Colitis, Ulcerative; Female; Growth; Gr | 1975 |
Effect of sulfasalazine and its analogs on fertility in male rats.
Topics: Animals; Body Weight; Fertility; Male; Prostaglandin Antagonists; Prostaglandins; Rats; Rats, Inbred | 1988 |
Editorial: Sulphasalazine-induced lung disease.
Topics: Adult; Body Weight; Colitis, Ulcerative; Cough; Dyspnea; Eosinophilia; Female; Humans; Hypersensitiv | 1974 |
Regional enteritis and growth retardation without intestinal symptoms.
Topics: Adolescent; Anemia, Hypochromic; Body Weight; Crohn Disease; Follow-Up Studies; Growth Disorders; Hu | 1973 |