Page last updated: 2024-11-04

sulfasalazine and Bladder Cancer

sulfasalazine has been researched along with Bladder Cancer in 6 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Research Excerpts

ExcerptRelevanceReference
" Sulfasalazine (SSZ), a drug used in the treatment of rheumatoid arthritis (RA), inhibits glutamate-cystine transport, and suppressed CD44v-dependent tumor growth and increased sensitivity to cytotoxic drugs in an in vivo study."3.83Potential of sulfasalazine as a therapeutic sensitizer for CD44 splice variant 9-positive urogenital cancer. ( Kubo, T; Morikawa, A; Morita, T; Nagano, O; Saya, H; Takayama, T, 2016)
"The patient was diagnosed with reactive arthritis associated with BCG intravesical injection therapy, as three typical symptoms were observed (bilateral conjunctivitis, urethritis, polyarthritis)."1.72[A Case of Reactive Arthritis after BCG Intravesical Infusion Therapy Successfully Treated with Salazosulfapyridine]. ( Endo, T; Ishitsuka, R; Kinase, S; Oguni, H; Takahashi, R; Tsutsumi, M; Yanagihashi, R, 2022)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Takahashi, R1
Kinase, S1
Yanagihashi, R1
Ishitsuka, R1
Endo, T1
Oguni, H1
Tsutsumi, M1
Ogihara, K1
Kikuchi, E1
Okazaki, S1
Hagiwara, M1
Takeda, T1
Matsumoto, K1
Kosaka, T1
Mikami, S1
Saya, H2
Oya, M1
Ye, P1
Mimura, J1
Okada, T1
Sato, H1
Liu, T1
Maruyama, A1
Ohyama, C1
Itoh, K1
Takayama, T1
Kubo, T1
Morikawa, A1
Morita, T1
Nagano, O1
Espin Jaime, MT1
Moran Penco, JM1
Garcia Agundez, JA1
Caballero Loscos, MJ1
Sanjuan Rodriguez, S1
Botello Martinez, F1
Gomez de Tbjada, R1
Laguna Alvarez, E1
Benitez Rodriguez, I1
Filiadis, IF1
Georgiou, IA1
Giannakopoulos, X1

Other Studies

6 other studies available for sulfasalazine and Bladder Cancer

ArticleYear
[A Case of Reactive Arthritis after BCG Intravesical Infusion Therapy Successfully Treated with Salazosulfapyridine].
    Hinyokika kiyo. Acta urologica Japonica, 2022, Volume: 68, Issue:5

    Topics: Administration, Intravesical; Aged; Arthritis, Reactive; BCG Vaccine; Carcinoma, Transitional Cell;

2022
Sulfasalazine could modulate the CD44v9-xCT system and enhance cisplatin-induced cytotoxic effects in metastatic bladder cancer.
    Cancer science, 2019, Volume: 110, Issue:4

    Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation

2019
Nrf2- and ATF4-dependent upregulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition.
    Molecular and cellular biology, 2014, Sep-15, Volume: 34, Issue:18

    Topics: Activating Transcription Factor 4; Amino Acid Transport System y+; Antineoplastic Agents; Boronic Ac

2014
Potential of sulfasalazine as a therapeutic sensitizer for CD44 splice variant 9-positive urogenital cancer.
    Medical oncology (Northwood, London, England), 2016, Volume: 33, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arthritis, Rheumatoid; Humans; Hyaluronan Rece

2016
Urinary bladder cancer in a girl with a slow-acetylator genotype and treated with sulphasalazine.
    British journal of urology, 1997, Volume: 80, Issue:1

    Topics: Acetyltransferases; Antineoplastic Agents; Carcinoma, Papillary; Child; Female; Humans; Phenotype; S

1997
Urinary bladder cancer in a girl with a slow-acetylator genotype and treated with sulphasalazine.
    British journal of urology, 1998, Volume: 81, Issue:2

    Topics: Acetylation; Anti-Inflammatory Agents; Female; Humans; Phenotype; Sulfasalazine; Urinary Bladder Neo

1998