sulfasalazine has been researched along with Bilateral Headache in 10 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nausea was the most frequent side effect: 32%, 23%, 49% in the SASP, MTX, and SASP + MTX groups respectively (p = 0." | 6.69 | Combination therapy in early rheumatoid arthritis: a randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components. ( Cantagrel, A; Combe, B; Dougados, M; Goupille, P; Leirisalo-Repo, M; Meusser, S; Olive, P; Paimela, L; Peldan, K; Rau, R; Schattenkirchner, M; Zeidler, H, 1999) |
| "Nausea was the most frequent side effect: 32%, 23%, 49% in the SASP, MTX, and SASP + MTX groups respectively (p = 0." | 2.69 | Combination therapy in early rheumatoid arthritis: a randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components. ( Cantagrel, A; Combe, B; Dougados, M; Goupille, P; Leirisalo-Repo, M; Meusser, S; Olive, P; Paimela, L; Peldan, K; Rau, R; Schattenkirchner, M; Zeidler, H, 1999) |
| "It is concluded that maintenance treatment of ulcerative colitis with sulphasalazine should be continued indefinitely unless contraindicated by side effects." | 2.64 | A controlled therapeutic trial of long-term maintenance treatment of ulcerative colitis with sulphazalazine (Salazopyrin). ( Dissanayake, AS; Truelove, SC, 1973) |
| "Early diagnosis of intracranial hypertension is important in patients with ulcerative colitis receiving 5 ASA treatment to prevent visual complications." | 1.35 | Drug induced intracranial hypertension associated with sulphasalazine treatment. ( Kansu, T; Sevgi, E; Varli, K; Yalcin, G, 2008) |
| "Use of sulphasalazine in ulcerative colitis patients is hampered by a variety of side-effects, including male infertility." | 1.31 | Sulphasalazine and 5-aminosalicylic acid in long-term treatment of ulcerative colitis: report on tolerance and side-effects. ( Crispino, P; Di Paolo, MC; Iacopini, F; Paoluzi, OA; Paoluzi, P; Pica, R; Rivera, M; Spera, G, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jeimy, S | 1 |
| McRae, K | 1 |
| Pattani, R | 1 |
| Sevgi, E | 1 |
| Yalcin, G | 1 |
| Kansu, T | 1 |
| Varli, K | 1 |
| Huang, JL | 1 |
| Chen, LC | 1 |
| Nakase, H | 1 |
| Itani, T | 1 |
| Mimura, J | 1 |
| Kawasaki, T | 1 |
| Komori, H | 1 |
| Hashimoto, K | 1 |
| Chiba, T | 1 |
| Dougados, M | 1 |
| Combe, B | 1 |
| Cantagrel, A | 1 |
| Goupille, P | 1 |
| Olive, P | 1 |
| Schattenkirchner, M | 1 |
| Meusser, S | 1 |
| Paimela, L | 1 |
| Rau, R | 1 |
| Zeidler, H | 1 |
| Leirisalo-Repo, M | 1 |
| Peldan, K | 1 |
| Di Paolo, MC | 1 |
| Paoluzi, OA | 1 |
| Pica, R | 1 |
| Iacopini, F | 1 |
| Crispino, P | 1 |
| Rivera, M | 1 |
| Spera, G | 1 |
| Paoluzi, P | 1 |
| Das, KM | 1 |
| Eastwood, MA | 1 |
| McManus, JP | 1 |
| Sircus, W | 1 |
| Dissanayake, AS | 1 |
| Truelove, SC | 1 |
| Kater, F | 1 |
| Collins, JR | 1 |
2 trials available for sulfasalazine and Bilateral Headache
| Article | Year |
|---|---|
Combination therapy in early rheumatoid arthritis: a randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Administration Schedule; Drug | 1999 |
A controlled therapeutic trial of long-term maintenance treatment of ulcerative colitis with sulphazalazine (Salazopyrin).
Topics: Biopsy; Blood Cell Count; Blood Sedimentation; Clinical Trials as Topic; Colitis, Ulcerative; Headac | 1973 |
8 other studies available for sulfasalazine and Bilateral Headache
| Article | Year |
|---|---|
A 63-year-old returned traveller with fever, rash, hepatitis and eosinophilia.
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Live | 2018 |
Drug induced intracranial hypertension associated with sulphasalazine treatment.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Female; Headache; Humans; Intra | 2008 |
Sulphasalazine in the treatment of children with chronic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Clinical Trials as T | 1998 |
Colonic ulceration caused by administration of loxoprofen sodium.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Chronic Disease; Colitis, Ulcerative; Colonoscopy; | 1999 |
Sulphasalazine and 5-aminosalicylic acid in long-term treatment of ulcerative colitis: report on tolerance and side-effects.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Desensitization, Im | 2001 |
Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype.
Topics: Acetylation; Agranulocytosis; Aminosalicylic Acids; Anemia, Hemolytic; Colitis, Ulcerative; Crohn Di | 1973 |
[Hemolysis, formation of Heinz bodies and of methemoglobin under therapy with Azulfidine (author's transl)].
Topics: Adult; Colitis, Ulcerative; Cyanosis; Diarrhea; Erythrocytes; Female; Headache; Heinz Bodies; Hemato | 1974 |
Adverse reactions to salicylazosulfapyridine (azulfidine) in the treatment of ulcerative colitis.
Topics: Adult; Agranulocytosis; Colitis, Ulcerative; Dermatitis; Exanthema; Headache; Hematologic Diseases; | 1968 |