Page last updated: 2024-11-04

sulfasalazine and Bilateral Headache

sulfasalazine has been researched along with Bilateral Headache in 10 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Research Excerpts

ExcerptRelevanceReference
"Nausea was the most frequent side effect: 32%, 23%, 49% in the SASP, MTX, and SASP + MTX groups respectively (p = 0."6.69Combination therapy in early rheumatoid arthritis: a randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components. ( Cantagrel, A; Combe, B; Dougados, M; Goupille, P; Leirisalo-Repo, M; Meusser, S; Olive, P; Paimela, L; Peldan, K; Rau, R; Schattenkirchner, M; Zeidler, H, 1999)
"Nausea was the most frequent side effect: 32%, 23%, 49% in the SASP, MTX, and SASP + MTX groups respectively (p = 0."2.69Combination therapy in early rheumatoid arthritis: a randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components. ( Cantagrel, A; Combe, B; Dougados, M; Goupille, P; Leirisalo-Repo, M; Meusser, S; Olive, P; Paimela, L; Peldan, K; Rau, R; Schattenkirchner, M; Zeidler, H, 1999)
"It is concluded that maintenance treatment of ulcerative colitis with sulphasalazine should be continued indefinitely unless contraindicated by side effects."2.64A controlled therapeutic trial of long-term maintenance treatment of ulcerative colitis with sulphazalazine (Salazopyrin). ( Dissanayake, AS; Truelove, SC, 1973)
"Early diagnosis of intracranial hypertension is important in patients with ulcerative colitis receiving 5 ASA treatment to prevent visual complications."1.35Drug induced intracranial hypertension associated with sulphasalazine treatment. ( Kansu, T; Sevgi, E; Varli, K; Yalcin, G, 2008)
"Use of sulphasalazine in ulcerative colitis patients is hampered by a variety of side-effects, including male infertility."1.31Sulphasalazine and 5-aminosalicylic acid in long-term treatment of ulcerative colitis: report on tolerance and side-effects. ( Crispino, P; Di Paolo, MC; Iacopini, F; Paoluzi, OA; Paoluzi, P; Pica, R; Rivera, M; Spera, G, 2001)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's3 (30.00)18.2507
2000's2 (20.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jeimy, S1
McRae, K1
Pattani, R1
Sevgi, E1
Yalcin, G1
Kansu, T1
Varli, K1
Huang, JL1
Chen, LC1
Nakase, H1
Itani, T1
Mimura, J1
Kawasaki, T1
Komori, H1
Hashimoto, K1
Chiba, T1
Dougados, M1
Combe, B1
Cantagrel, A1
Goupille, P1
Olive, P1
Schattenkirchner, M1
Meusser, S1
Paimela, L1
Rau, R1
Zeidler, H1
Leirisalo-Repo, M1
Peldan, K1
Di Paolo, MC1
Paoluzi, OA1
Pica, R1
Iacopini, F1
Crispino, P1
Rivera, M1
Spera, G1
Paoluzi, P1
Das, KM1
Eastwood, MA1
McManus, JP1
Sircus, W1
Dissanayake, AS1
Truelove, SC1
Kater, F1
Collins, JR1

Trials

2 trials available for sulfasalazine and Bilateral Headache

ArticleYear
Combination therapy in early rheumatoid arthritis: a randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components.
    Annals of the rheumatic diseases, 1999, Volume: 58, Issue:4

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Administration Schedule; Drug

1999
A controlled therapeutic trial of long-term maintenance treatment of ulcerative colitis with sulphazalazine (Salazopyrin).
    Gut, 1973, Volume: 14, Issue:12

    Topics: Biopsy; Blood Cell Count; Blood Sedimentation; Clinical Trials as Topic; Colitis, Ulcerative; Headac

1973

Other Studies

8 other studies available for sulfasalazine and Bilateral Headache

ArticleYear
A 63-year-old returned traveller with fever, rash, hepatitis and eosinophilia.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2018, 07-09, Volume: 190, Issue:27

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Live

2018
Drug induced intracranial hypertension associated with sulphasalazine treatment.
    Headache, 2008, Volume: 48, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Female; Headache; Humans; Intra

2008
Sulphasalazine in the treatment of children with chronic arthritis.
    Clinical rheumatology, 1998, Volume: 17, Issue:5

    Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Clinical Trials as T

1998
Colonic ulceration caused by administration of loxoprofen sodium.
    Internal medicine (Tokyo, Japan), 1999, Volume: 38, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Chronic Disease; Colitis, Ulcerative; Colonoscopy;

1999
Sulphasalazine and 5-aminosalicylic acid in long-term treatment of ulcerative colitis: report on tolerance and side-effects.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2001, Volume: 33, Issue:7

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Desensitization, Im

2001
Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype.
    The New England journal of medicine, 1973, Sep-06, Volume: 289, Issue:10

    Topics: Acetylation; Agranulocytosis; Aminosalicylic Acids; Anemia, Hemolytic; Colitis, Ulcerative; Crohn Di

1973
[Hemolysis, formation of Heinz bodies and of methemoglobin under therapy with Azulfidine (author's transl)].
    Medizinische Klinik, 1974, Mar-15, Volume: 69, Issue:11

    Topics: Adult; Colitis, Ulcerative; Cyanosis; Diarrhea; Erythrocytes; Female; Headache; Heinz Bodies; Hemato

1974
Adverse reactions to salicylazosulfapyridine (azulfidine) in the treatment of ulcerative colitis.
    Southern medical journal, 1968, Volume: 61, Issue:4

    Topics: Adult; Agranulocytosis; Colitis, Ulcerative; Dermatitis; Exanthema; Headache; Hematologic Diseases;

1968