sulfasalazine has been researched along with Bilateral Headache in 10 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Excerpt | Relevance | Reference |
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"Nausea was the most frequent side effect: 32%, 23%, 49% in the SASP, MTX, and SASP + MTX groups respectively (p = 0." | 6.69 | Combination therapy in early rheumatoid arthritis: a randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components. ( Cantagrel, A; Combe, B; Dougados, M; Goupille, P; Leirisalo-Repo, M; Meusser, S; Olive, P; Paimela, L; Peldan, K; Rau, R; Schattenkirchner, M; Zeidler, H, 1999) |
"Nausea was the most frequent side effect: 32%, 23%, 49% in the SASP, MTX, and SASP + MTX groups respectively (p = 0." | 2.69 | Combination therapy in early rheumatoid arthritis: a randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components. ( Cantagrel, A; Combe, B; Dougados, M; Goupille, P; Leirisalo-Repo, M; Meusser, S; Olive, P; Paimela, L; Peldan, K; Rau, R; Schattenkirchner, M; Zeidler, H, 1999) |
"It is concluded that maintenance treatment of ulcerative colitis with sulphasalazine should be continued indefinitely unless contraindicated by side effects." | 2.64 | A controlled therapeutic trial of long-term maintenance treatment of ulcerative colitis with sulphazalazine (Salazopyrin). ( Dissanayake, AS; Truelove, SC, 1973) |
"Early diagnosis of intracranial hypertension is important in patients with ulcerative colitis receiving 5 ASA treatment to prevent visual complications." | 1.35 | Drug induced intracranial hypertension associated with sulphasalazine treatment. ( Kansu, T; Sevgi, E; Varli, K; Yalcin, G, 2008) |
"Use of sulphasalazine in ulcerative colitis patients is hampered by a variety of side-effects, including male infertility." | 1.31 | Sulphasalazine and 5-aminosalicylic acid in long-term treatment of ulcerative colitis: report on tolerance and side-effects. ( Crispino, P; Di Paolo, MC; Iacopini, F; Paoluzi, OA; Paoluzi, P; Pica, R; Rivera, M; Spera, G, 2001) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (40.00) | 18.7374 |
1990's | 3 (30.00) | 18.2507 |
2000's | 2 (20.00) | 29.6817 |
2010's | 1 (10.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Jeimy, S | 1 |
McRae, K | 1 |
Pattani, R | 1 |
Sevgi, E | 1 |
Yalcin, G | 1 |
Kansu, T | 1 |
Varli, K | 1 |
Huang, JL | 1 |
Chen, LC | 1 |
Nakase, H | 1 |
Itani, T | 1 |
Mimura, J | 1 |
Kawasaki, T | 1 |
Komori, H | 1 |
Hashimoto, K | 1 |
Chiba, T | 1 |
Dougados, M | 1 |
Combe, B | 1 |
Cantagrel, A | 1 |
Goupille, P | 1 |
Olive, P | 1 |
Schattenkirchner, M | 1 |
Meusser, S | 1 |
Paimela, L | 1 |
Rau, R | 1 |
Zeidler, H | 1 |
Leirisalo-Repo, M | 1 |
Peldan, K | 1 |
Di Paolo, MC | 1 |
Paoluzi, OA | 1 |
Pica, R | 1 |
Iacopini, F | 1 |
Crispino, P | 1 |
Rivera, M | 1 |
Spera, G | 1 |
Paoluzi, P | 1 |
Das, KM | 1 |
Eastwood, MA | 1 |
McManus, JP | 1 |
Sircus, W | 1 |
Dissanayake, AS | 1 |
Truelove, SC | 1 |
Kater, F | 1 |
Collins, JR | 1 |
2 trials available for sulfasalazine and Bilateral Headache
Article | Year |
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Combination therapy in early rheumatoid arthritis: a randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Administration Schedule; Drug | 1999 |
A controlled therapeutic trial of long-term maintenance treatment of ulcerative colitis with sulphazalazine (Salazopyrin).
Topics: Biopsy; Blood Cell Count; Blood Sedimentation; Clinical Trials as Topic; Colitis, Ulcerative; Headac | 1973 |
8 other studies available for sulfasalazine and Bilateral Headache
Article | Year |
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A 63-year-old returned traveller with fever, rash, hepatitis and eosinophilia.
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Live | 2018 |
Drug induced intracranial hypertension associated with sulphasalazine treatment.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Female; Headache; Humans; Intra | 2008 |
Sulphasalazine in the treatment of children with chronic arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Clinical Trials as T | 1998 |
Colonic ulceration caused by administration of loxoprofen sodium.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Chronic Disease; Colitis, Ulcerative; Colonoscopy; | 1999 |
Sulphasalazine and 5-aminosalicylic acid in long-term treatment of ulcerative colitis: report on tolerance and side-effects.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Desensitization, Im | 2001 |
Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype.
Topics: Acetylation; Agranulocytosis; Aminosalicylic Acids; Anemia, Hemolytic; Colitis, Ulcerative; Crohn Di | 1973 |
[Hemolysis, formation of Heinz bodies and of methemoglobin under therapy with Azulfidine (author's transl)].
Topics: Adult; Colitis, Ulcerative; Cyanosis; Diarrhea; Erythrocytes; Female; Headache; Heinz Bodies; Hemato | 1974 |
Adverse reactions to salicylazosulfapyridine (azulfidine) in the treatment of ulcerative colitis.
Topics: Adult; Agranulocytosis; Colitis, Ulcerative; Dermatitis; Exanthema; Headache; Hematologic Diseases; | 1968 |