Page last updated: 2024-11-04

sulfasalazine and Behcet Syndrome

sulfasalazine has been researched along with Behcet Syndrome in 21 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Behcet Syndrome: Rare chronic inflammatory disease involving the small blood vessels. It is of unknown etiology and characterized by mucocutaneous ulceration in the mouth and genital region and uveitis with hypopyon. The neuro-ocular form may cause blindness and death. SYNOVITIS; THROMBOPHLEBITIS; gastrointestinal ulcerations; RETINAL VASCULITIS; and OPTIC ATROPHY may occur as well.

Research Excerpts

ExcerptRelevanceReference
"Although the treatment of Crohn's disease has improved significantly during past decade, the treatment of intestinal BD is still problematic."2.44[Pathogenesis and treatment of intestinal Behçet's disease]. ( Kim, HJ; Lee, CK, 2007)
"A FREQUENT AFFECTION: Ankylosing spondylitis is a chronic inflammatory rheumatism usually affecting young adults and characterized by an inflammatory enthesiopathy progressing towards ossification and ankylosis."2.42[Ankylosing spondylitis]. ( El Maghraoui, A, 2004)
"Sulfasalazine has been evaluated by several groups of investigators in ankylosing spondylitis and psoriatic arthritis."2.38Medical and surgical treatment of seronegative spondyloarthropathies. ( Kozin, F, 1991)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19904 (19.05)18.7374
1990's4 (19.05)18.2507
2000's9 (42.86)29.6817
2010's4 (19.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hu, YC1
Yang, YH1
Lin, YT1
Wang, LC1
Yu, HH1
Lee, JH1
Chiang, BL1
Butt, SU1
McNeil, J1
Lopalco, G1
Rigante, D1
Venerito, V1
Fabiani, C1
Franceschini, R1
Barone, M1
Lapadula, G1
Galeazzi, M1
Frediani, B1
Iannone, F1
Cantarini, L1
Jung, YS1
Cheon, JH1
Park, SJ1
Hong, SP1
Kim, TI1
Kim, WH1
Wedemeyer, H1
Kuipers, JG1
Streetz, K1
Mengel, M1
Schedel, I1
Kezmic, N1
Meier, P1
Zeidler, H1
Manns, MP1
Wagner, S1
Düzgün, N1
Ateş, A1
El Maghraoui, A1
Cobellis, L1
Pecori, E1
Rigatti, F1
Rotondi, M1
Scaffa, C1
De Lucia, E1
Messalli, EM1
Lee, CK1
Kim, HJ1
Kitauchi, S1
Ohata, H1
Kuroda, R1
Hirose, M1
Sakaguchi, A1
Nishi, S1
Nishioka, S1
Ikezawa, K1
Kashimura, H1
Hassan, M1
Nakahara, A1
Yanaka, A1
Matsuzaki, Y1
Mutoh, H1
Tanaka, N1
Hokama, A1
Yamashiro, T1
Kinjo, F1
Saito, A1
Kaklamani, VG1
Kaklamanis, PG1
Matsukawa, M1
Kouda, T1
Hisamatsu, T1
Kishikawa, H1
Fukuya, H1
Matsuoka, K1
Mizuno, Y1
Nishida, J1
Etaouil, N1
Benyahya, E1
Bennis, R1
Mkinsi, O1
Sawyer, A1
Walker, TM1
Terry, SI1
Kozin, F1
Johnson, DA1
Everhart, CW1
Foster, GR1
Smith, GE1
Kime, LR1
Pitcher, JL1

Reviews

6 reviews available for sulfasalazine and Behcet Syndrome

ArticleYear
Update on the Medical Management of Gastrointestinal Behçet's Disease.
    Mediators of inflammation, 2017, Volume: 2017

    Topics: Adrenal Cortex Hormones; Animals; Behcet Syndrome; Gastrointestinal Tract; Humans; Immunologic Facto

2017
Erosive arthritis in a patient with Behçet's disease.
    Rheumatology international, 2003, Volume: 23, Issue:5

    Topics: Adult; Antirheumatic Agents; Arthritis; Behcet Syndrome; Colchicine; Female; Genitalia, Female; Gluc

2003
[Ankylosing spondylitis].
    Presse medicale (Paris, France : 1983), 2004, Nov-20, Volume: 33, Issue:20

    Topics: Acquired Hyperostosis Syndrome; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; A

2004
[Pathogenesis and treatment of intestinal Behçet's disease].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2007, Volume: 50, Issue:1

    Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal; Behcet Syndrome; Colchicine; Colitis, Ulcerative; C

2007
[Therapy and nutrition for intestinal Behçet disease and simple ulcer].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 5

    Topics: Adult; Anhydrides; Behcet Syndrome; Colectomy; Enteral Nutrition; Ethanol; Female; Humans; Intestina

2001
Medical and surgical treatment of seronegative spondyloarthropathies.
    Current opinion in rheumatology, 1991, Volume: 3, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Psoriatic; Behcet Syndrome; Humans; Joint Diseas

1991

Trials

1 trial available for sulfasalazine and Behcet Syndrome

ArticleYear
Therapeutic alternatives in Behçet's syndrome.
    Clinical and experimental obstetrics & gynecology, 2007, Volume: 34, Issue:3

    Topics: Adult; Antirheumatic Agents; Antiviral Agents; Behcet Syndrome; Female; Humans; Injections, Subcutan

2007

Other Studies

14 other studies available for sulfasalazine and Behcet Syndrome

ArticleYear
Clinical manifestations and anti-TNF alpha therapy of juvenile Behçet's disease in Taiwan.
    BMC pediatrics, 2019, 07-11, Volume: 19, Issue:1

    Topics: Adalimumab; Adolescent; Antirheumatic Agents; Behcet Syndrome; Child; Colchicine; Drug Therapy, Comb

2019
Complete heart block in a Caucasian woman with Behçet's disease: a case report.
    Journal of medical case reports, 2016, Apr-19, Volume: 10

    Topics: Anti-Inflammatory Agents; Behcet Syndrome; Electrocardiography; Female; Heart Block; Humans; Middle

2016
Clinical course of intestinal Behcet's disease during the first five years.
    Digestive diseases and sciences, 2013, Volume: 58, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Behcet Syndrome; Disease Pr

2013
A rare manifestation of Behçet's syndrome: immunological correlates and successful treatment of an esophageal ulcer.
    Digestive diseases and sciences, 2003, Volume: 48, Issue:7

    Topics: Aged; Anti-Inflammatory Agents; Behcet Syndrome; Esophageal Diseases; Female; Humans; Prednisone; Su

2003
[Follow-up observation of intestinal Behçet disease treated with salazosulfapyridine and mesalazine for 8 years and 9 months].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1998, Volume: 95, Issue:2

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Behcet Syndrome; Follow-Up Studie

1998
A case of Behçet's syndrome with esophageal involvement treated with salicylazosulfapyridine and prednisolone.
    Endoscopy, 1998, Volume: 30, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Behcet Syndrome; Colonoscopy; Drug Therapy, Combination; Esophagosc

1998
Behçet's colitis.
    Gastrointestinal endoscopy, 1999, Volume: 49, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Behcet Syndrome; Colitis, Ulcerative; Colonoscopy; Female;

1999
Treatment of Behçet's disease--an update.
    Seminars in arthritis and rheumatism, 2001, Volume: 30, Issue:5

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Behcet Syndrome; Chl

2001
Combination therapy including pentoxifylline for entero-Behçet's disease.
    The Bulletin of Tokyo Dental College, 2001, Volume: 42, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Behcet Syndrome; Drug Therapy, Combination; Female; Humans; I

2001
Ankylosing spondylitis and Behçet's disease in combination. Two case reports.
    Joint bone spine, 2002, Volume: 69, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Behcet Syndrome; Colchicin

2002
Behçet's syndrome with ileal involvement--the beneficial effect of sulphasalazine.
    The West Indian medical journal, 1978, Volume: 27, Issue:4

    Topics: Adult; Behcet Syndrome; Humans; Ileum; Male; Radiography; Sulfasalazine

1978
Colitis in Behçet's syndrome.
    Gastrointestinal endoscopy, 1986, Volume: 32, Issue:1

    Topics: Behcet Syndrome; Colitis; Colon; Female; Humans; Middle Aged; Prednisone; Sulfasalazine

1986
Behçet's colitis with oesophageal ulceration treated with sulphasalazine and cyclosporin.
    Journal of the Royal Society of Medicine, 1988, Volume: 81, Issue:9

    Topics: Behcet Syndrome; Colitis; Cyclosporins; Drug Therapy, Combination; Esophagitis; Female; Humans; Midd

1988
The colitis of Behcet's disease: a separate entity? Colonoscopic findings and literature review.
    The American journal of digestive diseases, 1973, Volume: 18, Issue:11

    Topics: Adult; Behcet Syndrome; Biopsy; Colitis, Ulcerative; Humans; Male; Proctoscopy; Radiography; Sulfasa

1973