sulfasalazine has been researched along with B16 Melanoma in 2 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulfasalazine is an inhibitor of xCT that is known to increase cellular oxidative stress, giving it anti-tumor potential." | 1.48 | Sulfasalazine, an inhibitor of the cystine-glutamate antiporter, reduces DNA damage repair and enhances radiosensitivity in murine B16F10 melanoma. ( Kanai, E; Maruo, T; Nagane, M; Shibata, Y; Shimizu, T; Yamashita, T; Yoshioka, C, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lang, X | 1 |
| Green, MD | 1 |
| Wang, W | 1 |
| Yu, J | 1 |
| Choi, JE | 1 |
| Jiang, L | 1 |
| Liao, P | 1 |
| Zhou, J | 1 |
| Zhang, Q | 1 |
| Dow, A | 1 |
| Saripalli, AL | 1 |
| Kryczek, I | 1 |
| Wei, S | 1 |
| Szeliga, W | 1 |
| Vatan, L | 1 |
| Stone, EM | 1 |
| Georgiou, G | 1 |
| Cieslik, M | 1 |
| Wahl, DR | 1 |
| Morgan, MA | 1 |
| Chinnaiyan, AM | 1 |
| Lawrence, TS | 1 |
| Zou, W | 1 |
| Nagane, M | 1 |
| Kanai, E | 1 |
| Shibata, Y | 1 |
| Shimizu, T | 1 |
| Yoshioka, C | 1 |
| Maruo, T | 1 |
| Yamashita, T | 1 |
2 other studies available for sulfasalazine and B16 Melanoma
| Article | Year |
|---|---|
Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11.
Topics: Amino Acid Transport System y+; Animals; Antineoplastic Agents, Immunological; CD8-Positive T-Lympho | 2019 |
Sulfasalazine, an inhibitor of the cystine-glutamate antiporter, reduces DNA damage repair and enhances radiosensitivity in murine B16F10 melanoma.
Topics: Animals; Antiporters; Cell Cycle; Cell Survival; Comet Assay; Cystine; DNA Damage; DNA Repair; Femal | 2018 |