sulfasalazine has been researched along with Arthritis, Reactive in 34 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Arthritis, Reactive: An aseptic, inflammatory arthritis developing secondary to a primary extra-articular infection, most typically of the GASTROINTESTINAL TRACT or UROGENITAL SYSTEM. The initiating trigger pathogens are usually SHIGELLA; SALMONELLA; YERSINIA; CAMPYLOBACTER; or CHLAMYDIA TRACHOMATIS. Reactive arthritis is strongly associated with HLA-B27 ANTIGEN.
| Excerpt | Relevance | Reference |
|---|---|---|
| " All 4 had infectious gastroenteritis and chronic Reiter's syndrome with arthritis and enthesopathy that persisted despite treatment in 3 with antiinflammatory drugs and 1 with sulfasalazine for long periods." | 3.68 | An acute remission of Reiter's syndrome in male patients treated with bromocriptine. ( Bravo, G; Lavalle, C; Zazueta, B, 1992) |
| "Sulfasalazine was indicated in two cases." | 3.01 | Reactive arthritis occurring after COVID-19 infection: a narrative review. ( Abbes, M; Dhahri, R; Gharsallah, I; Louzir, B; Mehmli, T; Metoui, L; Slouma, M, 2023) |
| "To determine whether sulfasalazine (SSZ) at a dosage of 2,000 mg/day is effective in the treatment of reactive arthritis (ReA) that has been unresponsive to nonsteroidal antiinflammatory drug (NSAID) therapy." | 2.68 | Comparison of sulfasalazine and placebo in the treatment of reactive arthritis (Reiter's syndrome). A Department of Veterans Affairs Cooperative Study. ( Alepa, FP; Anderson, RJ; Balestra, DJ; Blackburn, WD; Budiman-Mak, E; Buxbaum, J; Cannon, GW; Clegg, DO; Cohen, MR; Cush, JJ; Haakenson, CM; Henderson, WG; Higashida, J; Inman, RD; Mahowald, ML; Makkena, R; Manaster, BJ; Mejias, E; Parhami, N; Reda, DJ; Schumacher, HR; Silverman, SL; Vasey, FB; Ward, RH; Weisman, MH, 1996) |
| "A FREQUENT AFFECTION: Ankylosing spondylitis is a chronic inflammatory rheumatism usually affecting young adults and characterized by an inflammatory enthesiopathy progressing towards ossification and ankylosis." | 2.42 | [Ankylosing spondylitis]. ( El Maghraoui, A, 2004) |
| " All available evidence indicates that short term antibacterial treatment has no effect on the prognosis and final outcome of ReA, and the results with long term administration of antibacterials are also overall poor." | 2.41 | Bacteria-Triggered reactive arthritis: implications for antibacterial treatment. ( Toivanen, A, 2001) |
| "Since reactive arthritis is induced by specific urogenital or enterogenic bacteriae, and since the gut is implicated in different forms of spondyloarthropathies, especially in IBD, it was clear that the gut could play an important role by permitting exogenous factors to enter the body." | 2.39 | The role of gut inflammation in the pathogenesis of spondyloarthropathies. ( Cuvelier, C; De Vos, M; Mielants, H; Veys, EM, 1996) |
| "Sulfasalazine, which has an effect in the acute exacerbations of ankylosing spondylitis, is probably also effective in chronic reactive arthritis." | 2.38 | Are antibiotics of any use in reactive arthritis? ( Leirisalo-Repo, M, 1993) |
| "The patient was diagnosed with reactive arthritis associated with BCG intravesical injection therapy, as three typical symptoms were observed (bilateral conjunctivitis, urethritis, polyarthritis)." | 1.72 | [A Case of Reactive Arthritis after BCG Intravesical Infusion Therapy Successfully Treated with Salazosulfapyridine]. ( Endo, T; Ishitsuka, R; Kinase, S; Oguni, H; Takahashi, R; Tsutsumi, M; Yanagihashi, R, 2022) |
| "Streptococcal toxic shock syndrome is a potentially lethal condition with an increasing incidence over the last 30 years." | 1.37 | Saline breast implant fluid collection and reactive arthritis in a patient with streptococcal toxic shock syndrome. ( Kohannim, O; Rubin, Z; Taylor, M, 2011) |
| "Reactive arthritis is an autoimmune disease that develops 2-4 weeks after a triggering infection, resulting mainly in synovitis/enthesitis of the lower limbs, but with a wide array of possible extra-articular manifestations." | 1.36 | Infliximab for reactive arthritis secondary to Chlamydia trachomatis infection. ( Schafranski, MD, 2010) |
| "At age 41 mo, reactive arthritis was diagnosed." | 1.31 | Management of reactive arthritis in a juvenile gorilla (Gorilla gorilla gorilla) with long-term sulfasalazine therapy. ( Marks, SK; Neiffer, DL; Rothschild, BM; Urvater, JA; Watkins, DI, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (5.88) | 18.7374 |
| 1990's | 16 (47.06) | 18.2507 |
| 2000's | 7 (20.59) | 29.6817 |
| 2010's | 6 (17.65) | 24.3611 |
| 2020's | 3 (8.82) | 2.80 |
| Authors | Studies |
|---|---|
| Slouma, M | 1 |
| Abbes, M | 1 |
| Mehmli, T | 1 |
| Dhahri, R | 1 |
| Metoui, L | 1 |
| Gharsallah, I | 1 |
| Louzir, B | 1 |
| Takahashi, R | 1 |
| Kinase, S | 1 |
| Yanagihashi, R | 1 |
| Ishitsuka, R | 1 |
| Endo, T | 1 |
| Oguni, H | 1 |
| Tsutsumi, M | 1 |
| Märker-Hermann, E | 1 |
| Hsing, YE | 1 |
| Walker, J | 1 |
| Lang, M | 1 |
| Fish, J | 1 |
| Covelli, C | 1 |
| Schreiber, BE | 1 |
| Hoversten, P | 1 |
| Beachey, J | 1 |
| Pham, M | 1 |
| Bhagra, A | 1 |
| Manimegalai, N | 1 |
| Rajamurugan, PS | 1 |
| Rajendran, CP | 1 |
| Rukmangatharajan, S | 1 |
| Rajeshwari, S | 1 |
| Ravichandran, R | 1 |
| Vasanthy, N | 1 |
| Schafranski, MD | 1 |
| Ryser, C | 1 |
| Hasler, P | 1 |
| Kohannim, O | 1 |
| Rubin, Z | 1 |
| Taylor, M | 1 |
| Sigal, LH | 1 |
| El Maghraoui, A | 1 |
| Dougados, M | 1 |
| vam der Linden, S | 1 |
| Leirisalo-Repo, M | 2 |
| Huitfeldt, B | 1 |
| Juhlin, R | 1 |
| Veys, E | 1 |
| Zeidler, H | 1 |
| Kvien, TK | 1 |
| Olivieri, I | 1 |
| Dijkmans, B | 1 |
| Disla, E | 1 |
| Rhim, HR | 1 |
| Reddy, A | 1 |
| Taranta, A | 1 |
| Medina-Rodriguez, F | 1 |
| Jara, LJ | 1 |
| Miranda, JM | 1 |
| Lavalle, C | 2 |
| Fraga, A | 1 |
| Mielants, H | 1 |
| De Vos, M | 1 |
| Cuvelier, C | 1 |
| Veys, EM | 1 |
| Clegg, DO | 2 |
| Reda, DJ | 2 |
| Weisman, MH | 1 |
| Cush, JJ | 1 |
| Vasey, FB | 1 |
| Schumacher, HR | 1 |
| Budiman-Mak, E | 1 |
| Balestra, DJ | 1 |
| Blackburn, WD | 1 |
| Cannon, GW | 1 |
| Inman, RD | 2 |
| Alepa, FP | 1 |
| Mejias, E | 1 |
| Cohen, MR | 1 |
| Makkena, R | 1 |
| Mahowald, ML | 1 |
| Higashida, J | 1 |
| Silverman, SL | 1 |
| Parhami, N | 1 |
| Buxbaum, J | 1 |
| Haakenson, CM | 1 |
| Ward, RH | 1 |
| Manaster, BJ | 1 |
| Anderson, RJ | 1 |
| Henderson, WG | 1 |
| Egsmose, C | 1 |
| Hansen, TM | 1 |
| Andersen, LS | 1 |
| Beier, JM | 1 |
| Christensen, L | 1 |
| Ejstrup, L | 1 |
| Peters, ND | 1 |
| van der Heijde, DM | 1 |
| Ueno, M | 1 |
| Sugita, T | 1 |
| Murakami, T | 1 |
| Takata, I | 1 |
| Adebajo, AO | 1 |
| Zivony, D | 1 |
| Nocton, J | 1 |
| Wortmann, D | 1 |
| Esterly, N | 1 |
| Layton, MA | 1 |
| Dziedzic, K | 1 |
| Dawes, PT | 1 |
| Burmester, GR | 1 |
| Feist, E | 1 |
| Krause, A | 1 |
| Abdellatif, M | 1 |
| Pepmueller, PH | 1 |
| Moore, TL | 1 |
| Stone, M | 1 |
| Toivanen, A | 1 |
| Neiffer, DL | 1 |
| Rothschild, BM | 1 |
| Marks, SK | 1 |
| Urvater, JA | 1 |
| Watkins, DI | 1 |
| Youssef, PP | 1 |
| Bertouch, JV | 1 |
| Jones, PD | 1 |
| Bravo, G | 1 |
| Zazueta, B | 1 |
| Suschke, HJ | 1 |
| Neumann, V | 1 |
| Wright, V | 1 |
| Bourel, M | 1 |
| Pawlotsky, Y | 1 |
| Lenoir, P | 1 |
| Simon, M | 1 |
9 reviews available for sulfasalazine and Arthritis, Reactive
| Article | Year |
|---|---|
Reactive arthritis occurring after COVID-19 infection: a narrative review.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Reactive; COVID-19; Female; Humans; Male; | 2023 |
[[Reactive arthritis].
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthri | 2010 |
Update on reactive arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Reactive; Chlamydia Infections; Drug Therapy, Co | 2001 |
[Ankylosing spondylitis].
Topics: Acquired Hyperostosis Syndrome; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; A | 2004 |
Are antibiotics of any use in reactive arthritis?
Topics: Anti-Bacterial Agents; Arthritis, Reactive; Chlamydia Infections; Ciprofloxacin; Humans; Sulfasalazi | 1993 |
The role of gut inflammation in the pathogenesis of spondyloarthropathies.
Topics: Anti-Inflammatory Agents; Arthritis, Reactive; Cell Membrane Permeability; Colonoscopy; HLA-B27 Anti | 1996 |
Juvenile spondyloarthropathies.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Reactive; Child; Female; Germany; | 2000 |
Recent developments in the therapy of spondyloarthropathies.
Topics: Alleles; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Monoclonal; Antirheumati | 2000 |
Bacteria-Triggered reactive arthritis: implications for antibacterial treatment.
Topics: Anti-Bacterial Agents; Antirheumatic Agents; Arthritis, Reactive; Borrelia burgdorferi Group; Drug A | 2001 |
4 trials available for sulfasalazine and Arthritis, Reactive
| Article | Year |
|---|---|
Sulfasalazine in the treatment of spondylarthropathy. A randomized, multicenter, double-blind, placebo-controlled study.
Topics: Adult; Arthritis, Psoriatic; Arthritis, Reactive; Double-Blind Method; Female; Humans; Male; Middle | 1995 |
Comparison of sulfasalazine and placebo in the treatment of reactive arthritis (Reiter's syndrome). A Department of Veterans Affairs Cooperative Study.
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Reactive; Female; Humans; Longitudinal Studies; Male; Mi | 1996 |
Limited effect of sulphasalazine treatment in reactive arthritis. A randomised double blind placebo controlled trial.
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Reactive; Blood Sedimentation; Double-Blind Method; Fema | 1997 |
Comparison of sulfasalazine and placebo for the treatment of axial and peripheral articular manifestations of the seronegative spondylarthropathies: a Department of Veterans Affairs cooperative study.
Topics: Adult; Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Reactive; Double-Blind Method; Female; | 1999 |
21 other studies available for sulfasalazine and Arthritis, Reactive
| Article | Year |
|---|---|
[A Case of Reactive Arthritis after BCG Intravesical Infusion Therapy Successfully Treated with Salazosulfapyridine].
Topics: Administration, Intravesical; Aged; Arthritis, Reactive; BCG Vaccine; Carcinoma, Transitional Cell; | 2022 |
[Reactive arthritis - a disease almost forgotten?]
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Reactive; Bacterial Infections; HLA-B27 Antigen; | 2020 |
Bilateral interstitial keratitis with anterior stromal infiltrates associated with reactive arthritis.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Reactive; Corneal Strom | 2017 |
DRESS syndrome triple whammy: sulfasalazine, amoxicillin and HHV-7.
Topics: Adult; Amoxicillin; Anti-Infective Agents; Arthritis, Reactive; DNA, Viral; Dose-Response Relationsh | 2017 |
A rare cause of oligoarthritis with septic presentation.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Reactive; Diarrhea; Dysuria; Fever; Gastr | 2018 |
Childhood reactive arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Reactive; Child; Comorbidity; Humans; Keratosis; | 2008 |
Infliximab for reactive arthritis secondary to Chlamydia trachomatis infection.
Topics: Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Arthritis, Reactive; Chlamydia Infections; | 2010 |
Saline breast implant fluid collection and reactive arthritis in a patient with streptococcal toxic shock syndrome.
Topics: Anti-Infective Agents; Antirheumatic Agents; Arthritis, Reactive; Breast Implants; Female; Humans; M | 2011 |
Improvement in CD4 lymphocyte count in HIV-Reiter's syndrome after treatment with sulfasalazine.
Topics: Adult; Arthritis, Reactive; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; HIV Infections; Humans; Leuko | 1994 |
Sulfasalazine treatment in Reiter's syndrome patients may not be sufficient: comment on the article by Youssef et al.
Topics: Arthritis, Reactive; HIV Seropositivity; Humans; Sulfasalazine | 1993 |
The novel anti-rheumatic drug TA-383 has a macrophage migration enhancing activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Reactive; Cell Movement; Chemotactic Fa | 1997 |
Sulfasalazine and human immunodeficiency virus-associated reactive arthritis: comment on the article by Clegg et al.
Topics: Anti-Inflammatory Agents; Arthritis, Reactive; Controlled Clinical Trials as Topic; HIV Infections; | 1997 |
Juvenile Reiter's syndrome: a report of four cases.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, | 1998 |
Sacroiliitis in an HLA B27-negative patient following giardiasis.
Topics: Adult; Animals; Arthritis, Reactive; Blood Sedimentation; Diclofenac; Giardia lamblia; Giardiasis; H | 1998 |
[Reactive arthritis. Diagnosis, differential diagnosis and therapy].
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Reactive; Arthritis, R | 1999 |
Management of reactive arthritis in a juvenile gorilla (Gorilla gorilla gorilla) with long-term sulfasalazine therapy.
Topics: Animals; Antirheumatic Agents; Arthritis, Reactive; Dysentery, Bacillary; Gorilla gorilla; Growth Di | 2000 |
Successful treatment of human immunodeficiency virus-associated Reiter's syndrome with sulfasalazine.
Topics: Adult; Arthritis, Reactive; HIV; HIV Infections; Humans; Male; Sulfasalazine | 1992 |
An acute remission of Reiter's syndrome in male patients treated with bromocriptine.
Topics: Adult; Arthritis, Reactive; Bromocriptine; Dose-Response Relationship, Drug; Gastroenteritis; Humans | 1992 |
[Treatment of juvenile spondylarthritis and reactive arthritis with sulfasalazine].
Topics: Adolescent; Arthritis, Juvenile; Arthritis, Reactive; Child; Dose-Response Relationship, Drug; Drug | 1992 |
Perspectives in the aetiology of seronegative polyarthritis.
Topics: Anti-Inflammatory Agents; Arthritis; Arthritis, Reactive; HLA Antigens; HLA-B27 Antigen; Humans; Spo | 1988 |
[Ulcero-hemorrhagic rectocolotis and Fiessinger-Leroy-Reiter syndrome with inclusion cells].
Topics: Adult; Arthritis, Reactive; Chloramphenicol; Colistin; Colitis; Cytomegalovirus Infections; Humans; | 1968 |