sulfasalazine has been researched along with Arthritis, Degenerative in 7 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the expression and roles of TAM (Tyro3/Axl/Mer) receptor tyrosine kinases (TK) in synovial fluid and synovial tissue of patients with rheumatoid arthritis (RA)." | 8.12 | Elevated expression of TAM receptor tyrosine kinase in synovial fluid and synovial tissue of rheumatoid arthritis. ( Bai, M; Hu, F; Su, Y; Xu, L; Xue, J; Yao, R; Zheng, L; Zhong, H; Zhu, H, 2022) |
| "The aim of this study was to investigate the effects of a sulfasalazine-containing hyaluronic acid (SASP/HA) systems on in vitro anti-inflammation and the alleviation of cartilage degradation in both lipopolysaccharide (LPS)-stimulated synoviocytes and a rat model of monosodium iodoacetate (MIA)-induced osteoarthritis (OA)." | 7.88 | Attenuation of inflammation and cartilage degradation by sulfasalazine-containing hyaluronic acid on osteoarthritis rat model. ( Bae, JH; Kim, HJ; Kim, SE; Lee, JY; Lee, S; Min, K; Park, K; Shim, KS; Song, HR, 2018) |
| "To investigate the expression and roles of TAM (Tyro3/Axl/Mer) receptor tyrosine kinases (TK) in synovial fluid and synovial tissue of patients with rheumatoid arthritis (RA)." | 4.12 | Elevated expression of TAM receptor tyrosine kinase in synovial fluid and synovial tissue of rheumatoid arthritis. ( Bai, M; Hu, F; Su, Y; Xu, L; Xue, J; Yao, R; Zheng, L; Zhong, H; Zhu, H, 2022) |
| "The aim of this study was to investigate the effects of a sulfasalazine-containing hyaluronic acid (SASP/HA) systems on in vitro anti-inflammation and the alleviation of cartilage degradation in both lipopolysaccharide (LPS)-stimulated synoviocytes and a rat model of monosodium iodoacetate (MIA)-induced osteoarthritis (OA)." | 3.88 | Attenuation of inflammation and cartilage degradation by sulfasalazine-containing hyaluronic acid on osteoarthritis rat model. ( Bae, JH; Kim, HJ; Kim, SE; Lee, JY; Lee, S; Min, K; Park, K; Shim, KS; Song, HR, 2018) |
| "The effects of sulfasalazine (SASP) and its metabolites sulfapyridine (SP) and 5-aminosalicylic acid (5-ASA) were investigated on release of prostaglandins (PG) and leukotrienes (LT) from synovial tissue of 37 patients with osteoarthritis, chondrocalcinosis and rheumatoid arthritis." | 3.68 | [Effect of sulfasalazine and its metabolites on prostaglandin and leukotriene liberation from human synovial tissue]. ( Kleemeyer, K; Peskar, BA; Peskar, BM; Wittenberg, HR, 1991) |
| "Of a large importance in the treatment of the rheumatoid arthritis and of the osteoarthrosis is the method of clinical tests of non-steroidal antirheumatic drugs and of the so-called disease-activity modifying substances." | 1.27 | [Drug treatment of rheumatoid arthritis and osteoarthritis]. ( Pavelka, K; Trnavský, K, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, L | 1 |
| Xu, L | 1 |
| Hu, F | 1 |
| Xue, J | 1 |
| Bai, M | 1 |
| Yao, R | 1 |
| Zhu, H | 1 |
| Zhong, H | 1 |
| Su, Y | 1 |
| Kim, SE | 1 |
| Lee, JY | 1 |
| Shim, KS | 1 |
| Lee, S | 1 |
| Min, K | 1 |
| Bae, JH | 1 |
| Kim, HJ | 1 |
| Park, K | 1 |
| Song, HR | 1 |
| Nagashima, M | 1 |
| Asano, G | 1 |
| Yoshino, S | 1 |
| Wildy, KS | 1 |
| Wasko, MC | 1 |
| Wittenberg, HR | 1 |
| Kleemeyer, K | 1 |
| Peskar, BM | 1 |
| Peskar, BA | 1 |
| Simenon, G | 1 |
| Van Gossum, A | 1 |
| Adler, M | 1 |
| Rickaert, F | 1 |
| Appelboom, T | 1 |
| Trnavský, K | 1 |
| Pavelka, K | 1 |
1 review available for sulfasalazine and Arthritis, Degenerative
| Article | Year |
|---|---|
Current concepts regarding pharmacologic treatment of rheumatoid and osteoarthritis.
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antirheumat | 2001 |
6 other studies available for sulfasalazine and Arthritis, Degenerative
| Article | Year |
|---|---|
Elevated expression of TAM receptor tyrosine kinase in synovial fluid and synovial tissue of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Complement C3; Humans; Osteoarthritis; Receptor Protein-Tyrosine Kinases; Rhe | 2022 |
Attenuation of inflammation and cartilage degradation by sulfasalazine-containing hyaluronic acid on osteoarthritis rat model.
Topics: Animals; Cartilage; Hyaluronic Acid; Inflammation; Lipopolysaccharides; Osteoarthritis; Rats; Rats, | 2018 |
Imbalance in production between vascular endothelial growth factor and endostatin in patients with rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Collagen; Cysteine; Drug Therapy, Co | 2000 |
[Effect of sulfasalazine and its metabolites on prostaglandin and leukotriene liberation from human synovial tissue].
Topics: 6-Ketoprostaglandin F1 alpha; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Arthrit | 1991 |
Macroscopic and microscopic gut lesions in seronegative spondyloarthropathies.
Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents, Non-Steroidal; Colon; Colonoscopy; Female; Humans; | 1990 |
[Drug treatment of rheumatoid arthritis and osteoarthritis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cartilage, Articular; Humans; Joints | 1987 |