sulfasalazine has been researched along with Arthralgia in 7 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Arthralgia: Pain in the joint.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare efficacy and tolerability of combined therapy with methotrexate (MTX), sulfasalazine (SSZ) and hydroxychloroquine (HCQ) with MTX-monotherapy in patients with rheumatoid arthritis (RA)." | 9.13 | [Comparison of efficacy and tolerability of triple combination therapy (methotrexate + sulfasalazine + hydroxychloroquine) with methotrexate monotherapy in patients with rheumatoid arthritis]. ( Bochkova, AG; Bunchuk, NV; Gubar', EE, 2008) |
| " Sulfasalazine was administered in both groups for persistent disease or disease that evolved into a polyarthritis." | 9.12 | A randomized controlled trial of early intervention with intraarticular corticosteroids followed by sulfasalazine versus conservative treatment in early oligoarthritis. ( Emery, P; Green, MJ; Keenan, AM; Marzo-Ortega, H; Proudman, S; Wakefield, RJ, 2007) |
| "To compare the pain course between methotrexate (MTX)-refractory early rheumatoid arthritis (RA) patients randomized to infliximab (IFX) versus sulfasalazine (SSZ) plus hydroxychloroquine (HCQ)." | 5.41 | Pain Over Two Years After Start of Biologic Versus Conventional Combination Treatment in Early Rheumatoid Arthritis: Results From a Swedish Randomized Controlled Trial. ( Ernestam, S; Jöud, A; Lampa, J; Olofsson, T; Saevarsdottir, S; Schelin, MEC; van Vollenhoven, R; Wallman, JK, 2021) |
| "To compare efficacy and tolerability of combined therapy with methotrexate (MTX), sulfasalazine (SSZ) and hydroxychloroquine (HCQ) with MTX-monotherapy in patients with rheumatoid arthritis (RA)." | 5.13 | [Comparison of efficacy and tolerability of triple combination therapy (methotrexate + sulfasalazine + hydroxychloroquine) with methotrexate monotherapy in patients with rheumatoid arthritis]. ( Bochkova, AG; Bunchuk, NV; Gubar', EE, 2008) |
| " Sulfasalazine was administered in both groups for persistent disease or disease that evolved into a polyarthritis." | 5.12 | A randomized controlled trial of early intervention with intraarticular corticosteroids followed by sulfasalazine versus conservative treatment in early oligoarthritis. ( Emery, P; Green, MJ; Keenan, AM; Marzo-Ortega, H; Proudman, S; Wakefield, RJ, 2007) |
| "Optic neuritis is rarely the first symptom of AS." | 1.37 | Ankylosing spondylitis presented as unilateral optic neuritis in a young woman. ( Chen, JT; Chou, YS; Lu, DW, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Olofsson, T | 1 |
| Wallman, JK | 1 |
| Jöud, A | 1 |
| Schelin, MEC | 1 |
| Ernestam, S | 1 |
| van Vollenhoven, R | 1 |
| Saevarsdottir, S | 1 |
| Lampa, J | 1 |
| Gubar', EE | 1 |
| Bochkova, AG | 1 |
| Bunchuk, NV | 1 |
| Makay, B | 1 |
| Unsal, E | 1 |
| Anal, O | 1 |
| Güneş, D | 1 |
| Men, S | 1 |
| Cakmakçi, H | 1 |
| Ozer, E | 1 |
| Chou, YS | 1 |
| Lu, DW | 1 |
| Chen, JT | 1 |
| Tamaki, C | 1 |
| Miyatake, J | 1 |
| Yamagata, T | 1 |
| Nozaki, Y | 1 |
| Yu, H | 1 |
| Sugiyama, M | 1 |
| Ikoma, S | 1 |
| Kinoshita, K | 1 |
| Funauchi, M | 1 |
| Kanamaru, A | 1 |
| Lü, AP | 1 |
| He, YT | 1 |
| Zha, QL | 1 |
| Yan, XP | 1 |
| Su, L | 1 |
| Song, YJ | 1 |
| Zeng, SP | 1 |
| Liu, W | 1 |
| Feng, XH | 1 |
| Qian, X | 1 |
| Zhu, WH | 1 |
| Marzo-Ortega, H | 1 |
| Green, MJ | 1 |
| Keenan, AM | 1 |
| Wakefield, RJ | 1 |
| Proudman, S | 1 |
| Emery, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Randomized, Open, Multi-Center Trial Comparing TNF-Blockade + MTX to MTX+SSZ+HCQ in Patients With Early RA With an Inadequate Response to MTX[NCT00764725] | Phase 4 | 487 participants (Actual) | Interventional | 2002-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for sulfasalazine and Arthralgia
| Article | Year |
|---|---|
Pain Over Two Years After Start of Biologic Versus Conventional Combination Treatment in Early Rheumatoid Arthritis: Results From a Swedish Randomized Controlled Trial.
Topics: Adult; Aged; Antirheumatic Agents; Arthralgia; Arthritis, Rheumatoid; Biological Products; Drug Ther | 2021 |
[Comparison of efficacy and tolerability of triple combination therapy (methotrexate + sulfasalazine + hydroxychloroquine) with methotrexate monotherapy in patients with rheumatoid arthritis].
Topics: Adult; Aged; Antirheumatic Agents; Arthralgia; Arthritis, Rheumatoid; Dose-Response Relationship, Dr | 2008 |
[Correlations of clinical symptoms and treatment efficacy in patients with rheumatoid arthritis treated with Chinese herbal drugs or Western medicine].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthritis, Rheumatoid; Drugs, Chinese He | 2005 |
A randomized controlled trial of early intervention with intraarticular corticosteroids followed by sulfasalazine versus conservative treatment in early oligoarthritis.
Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthr | 2007 |
3 other studies available for sulfasalazine and Arthralgia
| Article | Year |
|---|---|
Chronic recurrent multifocal osteomyelitis in a patient with selective immunoglobulin M deficiency.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthralgia; Autoimmune Diseases; Biom | 2009 |
Ankylosing spondylitis presented as unilateral optic neuritis in a young woman.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Color Vision; Drug Therapy, Combination; | 2011 |
[Case of acne fulminans associated with hemophagocytosis].
Topics: Acne Vulgaris; Adult; Anti-Inflammatory Agents; Arthralgia; Drug Therapy, Combination; Histiocytosis | 2004 |