sulfasalazine has been researched along with Aplasia Pure Red Cell in 3 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 12-year-old girl with juvenile rheumatoid arthritis developed fulminant hepatic failure, thrombocytopenia and erythroid hypoplasia, which was confirmed by liver histology and bone marrow examination, 2 weeks after initiation of sulphasalazine therapy." | 1.30 | Successfully treated sulphasalazine-induced fulminant hepatic failure, thrombocytopenia and erythroid hypoplasia with intravenous immunoglobulin. ( Chen, LC; Hsieh, KH; Hsueh, C; Huang, JL; Hung, IJ; Lee, WY, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsai, CY | 1 |
| Yu, CL | 1 |
| Tsai, YY | 1 |
| Kung, YY | 1 |
| Wu, TH | 1 |
| Tsai, ST | 1 |
| Huang, JL | 1 |
| Hung, IJ | 1 |
| Chen, LC | 1 |
| Lee, WY | 1 |
| Hsueh, C | 1 |
| Hsieh, KH | 1 |
| Sheehan, T | 1 |
| Tansey, P | 1 |
| Cochran, KM | 1 |
| O'Donnell, JR | 1 |
3 other studies available for sulfasalazine and Aplasia Pure Red Cell
| Article | Year |
|---|---|
Pure red cell aplasia in a man with RA.
Topics: Aged; Arthritis, Rheumatoid; Danazol; Humans; Male; Methotrexate; Red-Cell Aplasia, Pure; Sulfasalaz | 1997 |
Successfully treated sulphasalazine-induced fulminant hepatic failure, thrombocytopenia and erythroid hypoplasia with intravenous immunoglobulin.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Follow-Up Studies; Hepatic Encephalopathy; | 1998 |
Inflammatory bowel disease, anaemia and sulphasalazine.
Topics: Adult; Anemia; Bone Marrow; Colitis, Ulcerative; Female; Humans; Red-Cell Aplasia, Pure; Sulfasalazi | 1985 |