Compounds > sulfasalazine
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sulfasalazine and Anemia, Hemolytic

sulfasalazine has been researched along with Anemia, Hemolytic in 21 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Anemia, Hemolytic: A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES).

Research Excerpts

ExcerptRelevanceReference
"Hemolytic anemia is a well-recognized complication of sulfasalazine treatment."1.26Hemolytic anemia in patients receiving sulfasalazine. ( Ali, MA; Castelli, M; Goodacre, RL; Hamilton, JD; Seaton, T; Vanderlinden, B, 1978)
"In 36 unselected patients with ulcerative colitis or Crohn's disease taking 4."1.26Hemolysis during salicylazosulfapyridine therapy. ( van Elferen, LW; van Hees, PA; van Rossum, JM; van Tongeren, JH, 1978)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199019 (90.48)18.7374
1990's1 (4.76)18.2507
2000's1 (4.76)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SPRIGGS, AI1
SMITH, RS1
GRIFFITH, H1
TRUELOVE, SC1
BOETTIGER, LE1
ENGSTEDT, L1
LAGERCRANTZ, R1
NYBERG, A1
BADE, HJ1
KEHOE, EL1
NEWCOMER, KL1
BEUTLER, E1
GARDNER, MD1
BARGEN, JA1
DICK, AP1
GRAYSON, MJ1
CARPENTER, RG1
PETRIE, A1
Bokström, H1
Holst, RM1
Hafström, O1
Swolin, B1
Johansson, ML1
Brunlöf, G1
Hedner, T1
Taffet, SL1
Das, KM2
Danielson, DA1
Douglas, SW1
Herzog, P1
Jick, H1
Porter, JB1
Freidin, N1
Mandel, EM1
Gafter, U1
Djaldetti, M1
Lyonnais, J1
Kaplinsky, N1
Frankl, O1
Goodacre, RL1
Ali, MA1
Vanderlinden, B1
Hamilton, JD1
Castelli, M1
Seaton, T1
van Hees, PA1
van Elferen, LW1
van Rossum, JM1
van Tongeren, JH1
Pounder, RE1
Craven, ER1
Henthorn, JS1
Bannatyne, JM1
Houtman, PM1
Stenger, AA1
Bruyn, GA1
Eastwood, MA1
McManus, JP1
Sircus, W1
Gabor, EP1
Cohen, SM1
Rosenthal, DS1
Karp, PJ1
Lehtinen, M1
Lehtinen, E1
Nikkilä, EA1

Reviews

1 review available for sulfasalazine and Anemia, Hemolytic

ArticleYear
Sulfasalazine. Adverse effects and desensitization.
    Digestive diseases and sciences, 1983, Volume: 28, Issue:9

    Topics: Anemia, Hemolytic; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Gastrointestinal D

1983

Other Studies

20 other studies available for sulfasalazine and Anemia, Hemolytic

ArticleYear
Heinz-body anaemia due to salicylazosulphapyridine.
    Lancet (London, England), 1958, May-17, Volume: 1, Issue:7029

    Topics: Anemia; Anemia, Hemolytic; Humans; Sulfanilamide; Sulfanilamides; Sulfasalazine; Sulfonamides

1958
THE OCCURRENCE OF HEINZ BODIES DURING AZULFIDINE TREATMENT OF ULCERATIVE COLITIS.
    Gastroenterologia, 1963, Volume: 100

    Topics: Anemia; Anemia, Hemolytic; Colitis; Colitis, Ulcerative; Heinz Bodies; Humans; Statistics as Topic;

1963
[HEMOLYTIC ANEMIA WITH THE FORMATION OF HEINZ BODIES AFTER SALAZOSULFAPYRIDINE THERAPY].
    Nederlands tijdschrift voor geneeskunde, 1963, Dec-14, Volume: 107

    Topics: Anemia; Anemia, Hemolytic; Erythrocytes; Heinz Bodies; Hemolysis; Pathology; Sulfanilamide; Sulfanil

1963
THROMBOEMBOLIC PHENOMENA IN ULCERATIVE COLITIS. TWO CASE REPORTS.
    Archives of internal medicine, 1964, Volume: 113

    Topics: Anemia; Anemia, Hemolytic; Autoimmune Diseases; Blood Coagulation; Chlordiazepoxide; Colitis; Coliti

1964
DRUG-INDUCED BLOOD DYSCRASIAS. III. HEMOLYTIC ANEMIA.
    JAMA, 1964, Jul-13, Volume: 189

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anemia; Anemia, Hemolytic; Black People; Drug Hypersensit

1964
HEMOLYTIC ANEMIA SECONDARY TO SALICYLAZOSULFAPYRIDINE THERAPY.
    JAMA, 1964, Oct-05, Volume: 190

    Topics: Anemia; Anemia, Hemolytic; Blood Cell Count; Colitis; Colitis, Ulcerative; Drug Therapy; Hematocrit;

1964
CONTROLLED TRIAL OF SULPHASALAZINE IN THE TREATMENT OF ULCERATIVE COLITIS.
    Gut, 1964, Volume: 5

    Topics: Anemia; Anemia, Hemolytic; Biomedical Research; Colitis; Colitis, Ulcerative; Drug Therapy; Gastroin

1964
Fetal hemolytic anemia associated with maternal sulfasalazine therapy during pregnancy.
    Acta obstetricia et gynecologica Scandinavica, 2006, Volume: 85, Issue:1

    Topics: Adult; Anemia, Hemolytic; Blood Transfusion, Intrauterine; Colitis, Ulcerative; Female; Fetal Diseas

2006
Drug-induced blood disorders.
    JAMA, 1984, Dec-21, Volume: 252, Issue:23

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Anemia, Hemolytic; Child; Female; Hematologic Diseases; Hu

1984
[Hemolytic anemia associated with folic acid deficiency due to salazopyrin].
    Harefuah, 1976, Volume: 91, Issue:3-4

    Topics: Anemia, Hemolytic; Folic Acid; Folic Acid Deficiency; Prednisone; Sulfasalazine

1976
[Production of Heinz bodies after administration of salicylaszosulfapyridine].
    L'union medicale du Canada, 1976, Volume: 105, Issue:2

    Topics: Adult; Anemia, Hemolytic; Erythrocytes; Female; Heinz Bodies; Humans; Male; Sulfasalazine

1976
Salicylazosulphapyridine-induced Heinz body anemia.
    Acta haematologica, 1978, Volume: 59, Issue:5

    Topics: Anemia, Hemolytic; Erythrocytes; Female; Heinz Bodies; Humans; Malabsorption Syndromes; Middle Aged;

1978
Hemolytic anemia in patients receiving sulfasalazine.
    Digestion, 1978, Volume: 17, Issue:6

    Topics: Anemia, Hemolytic; Colitis, Ulcerative; Crohn Disease; Electrophoresis, Starch Gel; Heinz Bodies; He

1978
Hemolysis during salicylazosulfapyridine therapy.
    The American journal of gastroenterology, 1978, Volume: 70, Issue:5

    Topics: Adolescent; Adult; Aged; Anemia, Hemolytic; Colitis, Ulcerative; Crohn Disease; Female; Hemolysis; H

1978
Red cell abnormalities associated with sulphasalazine maintenance therapy for ulcerative colitis.
    Gut, 1975, Volume: 16, Issue:3

    Topics: Anemia, Hemolytic; Colitis, Ulcerative; Erythrocyte Count; Erythrocytes, Abnormal; Heinz Bodies; Hem

1975
[Rheumatoid arthritis and anemia; various aspects concerning prevalence, pathogenesis, diagnosis and therapy].
    Nederlands tijdschrift voor geneeskunde, 1992, Jun-20, Volume: 136, Issue:25

    Topics: Anemia, Hemolytic; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Humans; Sulfasala

1992
Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype.
    The New England journal of medicine, 1973, Sep-06, Volume: 289, Issue:10

    Topics: Acetylation; Agranulocytosis; Aminosalicylic Acids; Anemia, Hemolytic; Colitis, Ulcerative; Crohn Di

1973
Letter: Hemolytic anemia as adverse reaction to salicylazosulfapyridine.
    The New England journal of medicine, 1973, Dec-20, Volume: 289, Issue:25

    Topics: Anemia, Hemolytic; Erythrocytes; Glucosephosphate Dehydrogenase; Humans; Sulfasalazine

1973
Ulcerative colitis and erythrocyte G6PD deficiency. Salicylazosulfapyridine-provoked hemolysis.
    JAMA, 1968, Aug-12, Volume: 205, Issue:7

    Topics: Adult; Anemia, Hemolytic; Colitis, Ulcerative; Glucosephosphate Dehydrogenase Deficiency; Hemolysis;

1968
Microangiopathic hemolytic anemia in ulcerative colitis: report of a case.
    Scandinavian journal of gastroenterology, 1968, Volume: 3, Issue:4

    Topics: Adult; Anemia, Hemolytic; Angiography; Anti-Bacterial Agents; Blood Cell Count; Bone Marrow Examinat

1968