Page last updated: 2024-11-04

sulfasalazine and Alopecia Circumscripta

sulfasalazine has been researched along with Alopecia Circumscripta in 6 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Research Excerpts

ExcerptRelevanceReference
"Thirty-nine patients with persistent alopecia areata received 3 g of oral sulfasalazine for 6 months, and terminal hair regrowth was quantified as no response, moderate response, or good response."9.13Treatment of persistent alopecia areata with sulfasalazine. ( Mahd, AA; Rashidi, T, 2008)
"Promising results have been published in the past with the use of sulfasalazine in alopecia areata."7.74Is there a role for sulfasalazine in the treatment of alopecia areata? ( Bakar, O; Gurbuz, O, 2007)
"Thirty-nine patients with persistent alopecia areata received 3 g of oral sulfasalazine for 6 months, and terminal hair regrowth was quantified as no response, moderate response, or good response."5.13Treatment of persistent alopecia areata with sulfasalazine. ( Mahd, AA; Rashidi, T, 2008)
"Promising results have been published in the past with the use of sulfasalazine in alopecia areata."3.74Is there a role for sulfasalazine in the treatment of alopecia areata? ( Bakar, O; Gurbuz, O, 2007)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rashidi, T1
Mahd, AA1
Alkhalifah, A1
Alsantali, A1
Wang, E1
McElwee, KJ1
Shapiro, J1
Misery, L1
Sannier, K1
Chastaing, M1
Le Gallic, G1
Bakar, O1
Gurbuz, O1
Ellis, CN1
Brown, MF1
Voorhees, JJ1
Thompson, DM1
Robinson, TW1
Lennard-Jones, J1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Combined CO2 Fractional Laser With Bimatoprost 0.03% in Treatment of Alopecia Areata[NCT05600673]Phase 1/Phase 230 participants (Actual)Interventional2019-01-01Completed
Efficacy of Fractional CO2 Laser Alone and as Transepidermal Drug Delivery for Different Modalities of Treatment in Alopecia Areata[NCT04003376]Phase 440 participants (Anticipated)Interventional2019-07-26Recruiting
Effectiveness and Safety of Tofacitinib in Patients With Extensive and Recalcitrant Alopecia Areata[NCT03800979]Phase 419 participants (Actual)Interventional2019-01-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Side Effects From Tofacitinib

Patients came back for follow-up every month during a total of 24 weeks of treatments and at weeks 28,36 and 48. (NCT03800979)
Timeframe: 48 weeks

Interventionparticipants (Number)
DyslipidemiaUpper respiratory tract infectionTuberculosisMyalgiaAcneWeight gainConstipation
Tofacitinib9611211

Reviews

1 review available for sulfasalazine and Alopecia Circumscripta

ArticleYear
Alopecia areata update: part II. Treatment.
    Journal of the American Academy of Dermatology, 2010, Volume: 62, Issue:2

    Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Alopecia Areata; Animals; Child; Cyclopropa

2010
Alopecia areata update: part II. Treatment.
    Journal of the American Academy of Dermatology, 2010, Volume: 62, Issue:2

    Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Alopecia Areata; Animals; Child; Cyclopropa

2010
Alopecia areata update: part II. Treatment.
    Journal of the American Academy of Dermatology, 2010, Volume: 62, Issue:2

    Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Alopecia Areata; Animals; Child; Cyclopropa

2010
Alopecia areata update: part II. Treatment.
    Journal of the American Academy of Dermatology, 2010, Volume: 62, Issue:2

    Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Alopecia Areata; Animals; Child; Cyclopropa

2010
Alopecia areata update: part II. Treatment.
    Journal of the American Academy of Dermatology, 2010, Volume: 62, Issue:2

    Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Alopecia Areata; Animals; Child; Cyclopropa

2010
Alopecia areata update: part II. Treatment.
    Journal of the American Academy of Dermatology, 2010, Volume: 62, Issue:2

    Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Alopecia Areata; Animals; Child; Cyclopropa

2010
Alopecia areata update: part II. Treatment.
    Journal of the American Academy of Dermatology, 2010, Volume: 62, Issue:2

    Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Alopecia Areata; Animals; Child; Cyclopropa

2010
Alopecia areata update: part II. Treatment.
    Journal of the American Academy of Dermatology, 2010, Volume: 62, Issue:2

    Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Alopecia Areata; Animals; Child; Cyclopropa

2010
Alopecia areata update: part II. Treatment.
    Journal of the American Academy of Dermatology, 2010, Volume: 62, Issue:2

    Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Alopecia Areata; Animals; Child; Cyclopropa

2010

Trials

1 trial available for sulfasalazine and Alopecia Circumscripta

ArticleYear
Treatment of persistent alopecia areata with sulfasalazine.
    International journal of dermatology, 2008, Volume: 47, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Alopecia Areata; Dose-Response Relationship, Drug; Drug Adm

2008

Other Studies

4 other studies available for sulfasalazine and Alopecia Circumscripta

ArticleYear
Treatment of alopecia areata with sulfasalazine.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:4

    Topics: Adult; Alopecia Areata; Anti-Inflammatory Agents, Non-Steroidal; Eyelashes; Hair; Humans; Immunosupp

2007
Is there a role for sulfasalazine in the treatment of alopecia areata?
    Journal of the American Academy of Dermatology, 2007, Volume: 57, Issue:4

    Topics: Adolescent; Adult; Alopecia Areata; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Middle

2007
Sulfasalazine for alopecia areata.
    Journal of the American Academy of Dermatology, 2002, Volume: 46, Issue:4

    Topics: Adolescent; Adult; Alopecia Areata; Diseases in Twins; Female; Humans; Immunosuppressive Agents; Mid

2002
Alopecia areata, vitiligo, scleroderma and ulcerative colitis.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:10

    Topics: Adult; Alopecia Areata; Barium Sulfate; Colitis, Ulcerative; Enema; Humans; Lichen Planus; Male; Pre

1974