sulfasalazine has been researched along with Alloxan Diabetes in 3 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It has been previously reported that aspirin inhibited the development of diabetic retinopathy in diabetic animals, raising the possibility that anti-inflammatory drugs may have beneficial effects on diabetic retinopathy." | 3.74 | Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy. ( Hatala, DA; Howell, SJ; Huang, K; Kern, TS; Zheng, L, 2007) |
| "Sulfasalazine treatment also increased inosine levels in sciatic nerves of diabetic rats." | 1.35 | Sulfasalazine blocks the development of tactile allodynia in diabetic rats. ( Berti-Mattera, LN; Kern, TS; Mitchell, R; Nemet, I; Siegel, RE, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berti-Mattera, LN | 1 |
| Kern, TS | 2 |
| Siegel, RE | 1 |
| Nemet, I | 1 |
| Mitchell, R | 1 |
| Zheng, L | 1 |
| Howell, SJ | 1 |
| Hatala, DA | 1 |
| Huang, K | 1 |
| Schmidt, M | 1 |
| Epstein, S | 1 |
| Maruta, K | 1 |
| Kawai, K | 1 |
| Burkart, V | 1 |
| Kiesel, U | 1 |
| Kolb, H | 1 |
3 other studies available for sulfasalazine and Alloxan Diabetes
| Article | Year |
|---|---|
Sulfasalazine blocks the development of tactile allodynia in diabetic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; Chromatography, High P | 2008 |
Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Death; Diabete | 2007 |
Modulation of arachidonic acid metabolism has limited effects on the development of type I diabetes in animal models.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic | 1989 |