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sulfasalazine and Allergy, Drug

sulfasalazine has been researched along with Allergy, Drug in 91 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Research Excerpts

ExcerptRelevanceReference
"We present an unusual case of a patient with extreme lymphoplasmacytosis and hepatic failure in association with a reaction to sulfasalazine and a concurrent Epstein-Barr virus (EBV) infection."8.82Extreme lymphoplasmacytosis and hepatic failure associated with sulfasalazine hypersensitivity reaction and a concurrent EBV infection--case report and review of the literature. ( Anastopoulos, HT; Ballesteros, E; Halmos, B; Schnipper, LE, 2004)
"Drug hypersensitivity syndrome (DHS) induced by sulfasalazine is a serious systemic delayed adverse drug reaction, which is associated with significant morbidity and mortality."8.12Drug hypersensitivity syndrome induced by sulfasalazine: A case report. ( Chen, DH; Guan, CL; Shen, GY; Xu, C; Zhang, YG; Zhou, HR, 2022)
"A 24-year-old female developed DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) as a result of sulfasalazine use."7.76[DRESS syndrome as a result of sulfasalazine use]. ( Bakker, RC; Segers, D; van der Mark, SC; van Wijngaarden, P, 2010)
" We describe a 60-year-old man with polyarthritis treated with sulfasalazine who developed DRESS and fulminant liver failure after additional vancomycin treatment."7.75Fulminant liver failure after vancomycin in a sulfasalazine-induced DRESS syndrome: fatal recurrence after liver transplantation. ( Candinas, D; Inderbitzin, D; Keller, M; Keogh, A; Mennicke, M; Pichler, WJ; Stickel, F; Wilkens, L; Yawalkar, N; Zawodniak, A, 2009)
" Two patients presented severe febrile skin eruption following drug intake (carbamazepine or sulfazalazine), with hypereosinophilia and hepatitis."7.71[DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome after sulfasalazine and carmazepine: report of two cases]. ( Catteau, B; Delcey, V; Devulder, B; Fauchais, AL; Hachulla, E; Hatron, PY; Launay, D; Legout, L; Michon-Pasturel, U; Queyrel, V, 2001)
"A severe adverse reaction to sulfasalazine therapy has been associated with hypersensitivity syndrome, the clinical features of which are similar to infectious mononucleosis."7.70Severe hypersensitivity syndrome due to sulfasalazine associated with reactivation of human herpesvirus 6. ( Hashimoto, K; Inagi, R; Tohyama, M; Urano, Y; Yahata, Y; Yamanishi, K; Yasukawa, M, 1998)
"We report the simultaneous development of fulminant hepatic failure and necrotizing pancreatitis in a patient treated with sulfasalazine."7.69Sulfasalazine-induced fulminant hepatic failure and necrotizing pancreatitis. ( Rubin, R, 1994)
"We present an unusual case of a patient with extreme lymphoplasmacytosis and hepatic failure in association with a reaction to sulfasalazine and a concurrent Epstein-Barr virus (EBV) infection."4.82Extreme lymphoplasmacytosis and hepatic failure associated with sulfasalazine hypersensitivity reaction and a concurrent EBV infection--case report and review of the literature. ( Anastopoulos, HT; Ballesteros, E; Halmos, B; Schnipper, LE, 2004)
"We report a 52-yr-old man with ulcerative colitis who developed sulfasalazine-induced pulmonary infiltration with eosinophilia (PIE syndrome), which resolved completely after withdrawal of this drug."4.78Pulmonary infiltration and eosinophilia associated with sulfasalazine therapy for ulcerative colitis: a case report and review of literature. ( Kishida, T; Kobayashi, M; Nomura, T; Yamada, T; Yamakado, S; Yoshida, Y, 1992)
"Drug hypersensitivity syndrome (DHS) induced by sulfasalazine is a serious systemic delayed adverse drug reaction, which is associated with significant morbidity and mortality."4.12Drug hypersensitivity syndrome induced by sulfasalazine: A case report. ( Chen, DH; Guan, CL; Shen, GY; Xu, C; Zhang, YG; Zhou, HR, 2022)
"A young woman thought to have seronegative rheumatoid arthritis developed Stevens-Johnson syndrome after treatment with sulfasalazine; this resolved with prednisone."3.79Giant cell myocarditis in a patient with a spondyloarthropathy after a drug hypersensitivity reaction. ( Cooper, LT; Davies, RA; Grenon, J; Mesana, TG; Mielniczuk, LM; Mitoff, PR; Veinot, JP, 2013)
"A 24-year-old female developed DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) as a result of sulfasalazine use."3.76[DRESS syndrome as a result of sulfasalazine use]. ( Bakker, RC; Segers, D; van der Mark, SC; van Wijngaarden, P, 2010)
" We describe a 60-year-old man with polyarthritis treated with sulfasalazine who developed DRESS and fulminant liver failure after additional vancomycin treatment."3.75Fulminant liver failure after vancomycin in a sulfasalazine-induced DRESS syndrome: fatal recurrence after liver transplantation. ( Candinas, D; Inderbitzin, D; Keller, M; Keogh, A; Mennicke, M; Pichler, WJ; Stickel, F; Wilkens, L; Yawalkar, N; Zawodniak, A, 2009)
"A 58-year-old woman with rheumatoid arthritis (RA) developed fever, skin eruptions, leukocytopenia, and thrombocytopenia, 3 weeks after treatment with sulfasalazine."3.74Sulfasalazine-induced hypersensitivity syndrome and hemophagocytic syndrome associated with reactivation of Epstein-Barr virus. ( Hatakeyama, T; Komatsuda, A; Okamoto, Y; Sawada, K; Wakui, H, 2008)
"We describe a patient with drug-induced hypersensitivity syndrome (DIHS) associated with human herpesvirus 6 (HHV-6) and cytomegalovirus (CMV) infection induced by sulfasalazine."3.73Drug-induced hypersensitivity syndrome associated with human herpesvirus 6 and cytomegalovirus reactivation. ( Hamaguchi, Y; Hasegawa, M; Komura, K; Nagai, M; Sato, S; Takehara, K; Yachie, A; Yukami, T, 2005)
"We report a case of drug hypersensibility syndrome (DRESS syndrome) developed one month after initiation of a treatment by sulfasalazine."3.73[DRESS syndrome to sulfasalzine]. ( Bourguignon, R; Paquet, P; Piérard, GE; Piérrard-Franchimont, C, 2006)
" Two patients presented severe febrile skin eruption following drug intake (carbamazepine or sulfazalazine), with hypereosinophilia and hepatitis."3.71[DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome after sulfasalazine and carmazepine: report of two cases]. ( Catteau, B; Delcey, V; Devulder, B; Fauchais, AL; Hachulla, E; Hatron, PY; Launay, D; Legout, L; Michon-Pasturel, U; Queyrel, V, 2001)
"A severe adverse reaction to sulfasalazine therapy has been associated with hypersensitivity syndrome, the clinical features of which are similar to infectious mononucleosis."3.70Severe hypersensitivity syndrome due to sulfasalazine associated with reactivation of human herpesvirus 6. ( Hashimoto, K; Inagi, R; Tohyama, M; Urano, Y; Yahata, Y; Yamanishi, K; Yasukawa, M, 1998)
"We report the simultaneous development of fulminant hepatic failure and necrotizing pancreatitis in a patient treated with sulfasalazine."3.69Sulfasalazine-induced fulminant hepatic failure and necrotizing pancreatitis. ( Rubin, R, 1994)
"Sulfasalazine may cause reversible male infertility, but it is entirely safe for use during pregnancy and lactation."2.37The safety of sulfasalazine: the gastroenterologists' experience. ( Sachar, DB, 1988)
"Sulfasalazine (SSZ), which has an arylamine sulfonamide structure, is an anti-inflammatory drug used in the treatment of many rheumatic diseases."1.46Sulfasalazine-Related Hypersensitivity Reactions in Patients With Rheumatic Diseases. ( Cildag, S; Senturk, T, 2017)
"A 22-year-old woman with ulcerative colitis developed skin eruptions, liver dysfunction, and atypical lymphocytes in the peripheral blood two weeks after she started taking salazosulfapyridine (SASP)."1.32Salazosulfapyridine induced hypersensitivity syndrome associated with reactivation of humanherpes virus 6. ( Goto, H; Kitagawa, K; Kunisaki, Y; Nagano, M, 2003)
"An 11-year-old girl with Crohn's disease was given 40 mg/kd/day of sulphasalazine after achieving remission with prednisone."1.30[Hypersensitivity to 5-aminosalicylic acid. Value of desensitization by oral route]. ( Aboufadel, A; Hermier, M; Lachaux, A; Le Gall, C; Loras-Duclaux, I, 1997)
"The development of a toxic hepatitis and dermatitis prompted interruption of the drug."1.29Sulfasalazine-associated encephalopathy in a patient with Crohn's disease. ( Achten, E; Dewilde, D; Mast, A; Pauwels, W; Schoonjans, R; Van Den Abeele, G; Van Maele, V, 1993)
"The development of toxic hepatitis and dermatitis prompted interruption of the drug."1.29Sulfasalazine-associated encephalopathy in a patient with Crohn's disease. ( Achten, E; Dewilde, D; Mast, A; Pauwels, W; Schoonjans, R; Van den Abeele, G; Van Maele, V, 1993)
"Sulfasalazine is an important therapeutic agent in the management of chronic inflammatory bowel disease (CIBD)."1.28Sulfasalazine desensitization in children and adolescents with chronic inflammatory bowel disease. ( Tolia, V, 1992)
" LST was negative before attempting desensitization and became positive when the dosage of SASP increased to 100 mg daily."1.27A case of salicylazosulfapyridine (Salazopyrin)-induced acute pancreatitis with positive lymphocyte stimulation test (LST). ( Arakawa, H; Chiba, M; Horie, Y; Ishida, H; Masamune, O, 1987)
"Two patients with ulcerative colitis and a past history of allergic reactions to sulfasalazine had similar reactions when treated with 5-aminosalicylic acid."1.27Adverse effects with oral 5-aminosalicyclic acid. ( Fardy, JM; Lloyd, DA; Reynolds, RP, 1988)
"Seventeen patients with ulcerative colitis and three patients with Crohn's disease exhibited different side effects during sulfasalazine therapy."1.26Desensitization of patients with inflammatory bowel disease to sulfasalazine. ( Das, KM; Taffet, SL, 1982)

Research

Studies (91)

TimeframeStudies, this research(%)All Research%
pre-199039 (42.86)18.7374
1990's18 (19.78)18.2507
2000's19 (20.88)29.6817
2010's12 (13.19)24.3611
2020's3 (3.30)2.80

Authors

AuthorsStudies
Hammond, S1
Olsson-Brown, A1
Grice, S1
Gibson, A1
Gardner, J1
Castrejón-Flores, JL1
Jolly, C1
Fisher, BA2
Steven, N2
Betts, C1
Pirmohamed, M1
Meng, X1
Naisbitt, DJ1
Chen, DH1
Zhou, HR1
Zhang, YG1
Shen, GY1
Xu, C1
Guan, CL1
Bojanini, L1
Sacco, K1
Maya Villamizar, JJ1
Wheeler, JA1
Ahmed, NH1
Gonzalez-Estrada, A1
Ford, M1
Sahbudin, I1
Filer, A1
Soga, K1
Itani, K1
Mitoff, PR1
Mesana, TG1
Mielniczuk, LM1
Grenon, J1
Veinot, JP1
Cooper, LT1
Davies, RA1
Cookson, H1
Creamer, D1
Walsh, S1
Descamps, V1
Tsutsumi, R1
Adachi, K1
Yoshida, Y2
Yamamoto, O1
Wada, S1
Kumagai, H1
Yokoyama, K1
Ito, T1
Miyauchi, A1
Sakamoto, S1
Imagawa, T1
Tulyeu, J1
Tanaka, M1
Yamagata, T1
Cildag, S1
Senturk, T1
Shenoy, P1
Misra, R1
Jain, M1
Agarwal, V1
Mennicke, M1
Zawodniak, A2
Keller, M1
Wilkens, L1
Yawalkar, N1
Stickel, F1
Keogh, A1
Inderbitzin, D1
Candinas, D1
Pichler, WJ2
Yeşilova, Z1
Kantarcioğlu, M1
Erçin, CN1
Safalioğlu, M1
Kilciler, G1
Koç, E1
Atli, M1
Uygun, A1
Santiago, F1
Gonçalo, M1
Vieira, R1
Coelho, S1
Figueiredo, A1
Lochmatter, P1
Beeler, A1
Yin, WH1
Zhang, HY1
Li, XF1
Ma, Y1
van der Mark, SC1
Segers, D1
Bakker, RC1
van Wijngaarden, P1
Sawada, S1
Takei, M1
Kunisaki, Y1
Goto, H1
Kitagawa, K1
Nagano, M1
Halmos, B1
Anastopoulos, HT1
Schnipper, LE1
Ballesteros, E1
BEUTLER, E1
Orita, M1
Katakura, Y1
Kobayashi, M2
Ishii, T1
Watanabe, Y1
Yotsuyanagi, H1
Suzuki, M1
Itoh, F1
Komura, K1
Hasegawa, M1
Hamaguchi, Y1
Yukami, T1
Nagai, M1
Yachie, A1
Sato, S1
Takehara, K1
Debarbieux, S1
Deroo-Berger, MC1
Grande, S1
Najioullah, F1
Kanitakis, J1
Faure, M1
Claudy, A1
Condat, B1
Zanditenas, D1
Collot, V1
Legoupil, N1
Cazals-Hatem, D1
Hauuy, MP1
Bonnet, J1
Ngo, Y1
Roucoules, J1
Blazquez, M1
Kampmann, P1
Højlyng, N1
Pedersen, M1
Bourguignon, R1
Piérrard-Franchimont, C1
Paquet, P1
Piérard, GE1
Nishimura, T1
Obata, H1
Fujino, H1
Sonoda, A1
Sakamoto, K1
Mizuno, C1
Mizuno, M1
Shima, T1
Nakajyo, S1
Fujiyama, Y1
Short, K1
Syn, WK1
Haydon, G1
Komatsuda, A1
Okamoto, Y1
Hatakeyama, T1
Wakui, H1
Sawada, K1
Tohyama, M2
Hashimoto, K2
Holdsworth, CD2
Losek, JD1
Werlin, SL1
Allan, RN1
Taffet, SL2
Das, KM2
van Hees, PA1
van Tongeren, JH1
Baillie, J1
Pullar, T1
Capell, HA1
Kirsner, JB1
Deutsch, S1
Hanauer, SB1
Pannier, R1
Hermann, GG1
Dor, PJ1
Vervloet, D1
Arnaud, A1
Charpin, J1
Kolbe, J1
Caughey, D1
Rainer, S1
Rubin, R1
Hessemer, CA1
Schinagl, EF1
Schoonjans, R2
Mast, A2
Van Den Abeele, G2
Dewilde, D2
Achten, E2
Van Maele, V2
Pauwels, W2
Lachaux, A1
Le Gall, C1
Loras-Duclaux, I1
Aboufadel, A1
Hermier, M1
Sentongo, TA1
Piccoli, DA1
Yahata, Y1
Yasukawa, M1
Inagi, R1
Urano, Y1
Yamanishi, K1
Bouyssou-Gauthier, ML1
Bédane, C1
Boulinguez, S1
Bonnetblanc, JM1
Paul, RH1
Toder, JS1
Cohen, RA1
Safer, L1
Braham, A1
Younes, R1
Bdioui, F1
Zili, J1
Saffar, H1
Cleveland, DB1
Doyle, JL1
Rinaggio, J1
Schneider, LC1
Queyrel, V1
Catteau, B1
Michon-Pasturel, U1
Fauchais, AL1
Delcey, V1
Launay, D1
Legout, L1
Hachulla, E1
Hatron, PY1
Devulder, B1
Várkonyi, V1
Török, I1
Márta, D1
Makovitzky, J1
Mihas, AA1
Goldenberg, DJ1
Slaughter, RL1
Chester, AC1
Diamond, LH1
Schreiner, GE1
Blackstone, MO1
Jacobs, E1
Paulet, P1
Rahier, J1
Kanner, RS1
Tedesco, FJ1
Kalser, MH1
Gulley, RM1
Mirza, A1
Kelly, CE1
Sotolongo, RP1
Neefe, LI1
Rudzki, C1
Ishak, KG1
Giaffer, MH1
O'Brien, CJ1
Yamakado, S1
Yamada, T1
Kishida, T1
Nomura, T1
Tolia, V1
Hautekeete, ML1
Bourgeois, N1
Potvin, P1
Duville, L1
Reynaert, H1
Devis, G1
Adler, M1
Klöppel, G1
Lioté, F1
Kuntz, D1
Merrin, P1
Williams, IA1
Pettersson, T1
Gripenberg, M1
Molander, G1
Friman, C1
Victorino, RM1
Maria, VA1
de Deus, J1
Pears, JS1
Morley, KD1
Mittal, PK1
Goyal, KK1
Gulati, R1
Jain, P1
Singh, GP1
Gremse, DA1
Bancroft, J1
Moyer, MS1
Donald, IP1
Wilkinson, SP1
Ribe, J1
Benkov, KJ1
Thung, SN1
Shen, SC1
LeLeiko, NS1
Haines, JD1
Jennings, PE1
Blandford, RL1
Rosenthal, FD1
Benfield, GF1
Asquith, P1
Cappello, M1
Puleo, A1
Calabrese, A1
Cipolla, C1
Orlando, A1
Gatto, G1
Oliva, L1
Cottone, M1
Chiba, M1
Horie, Y1
Ishida, H1
Arakawa, H1
Masamune, O1
Meyers, S2
Sachar, DB1
Foresti, V1
Tronci, M1
Ungaro, A1
Confalonieri, F1
Fardy, JM1
Lloyd, DA1
Reynolds, RP1
Maitra, AK1
Schmidt, H1
Uhl, N1
Hunstein, W1
Araki, Y1

Reviews

9 reviews available for sulfasalazine and Allergy, Drug

ArticleYear
Extreme lymphoplasmacytosis and hepatic failure associated with sulfasalazine hypersensitivity reaction and a concurrent EBV infection--case report and review of the literature.
    Annals of hematology, 2004, Volume: 83, Issue:4

    Topics: Adult; Diagnosis, Differential; Drug Hypersensitivity; Epstein-Barr Virus Infections; Humans; Leukoc

2004
[A case of salazosulfapyridine induced hypersensitivity syndrome].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2005, Volume: 102, Issue:5

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug Hypersensitivity; Female; Humans; Middle Aged; Sul

2005
[Drug-induced hypersensitivity syndrome: DIHS].
    Arerugi = [Allergy], 2007, Volume: 56, Issue:11

    Topics: Allopurinol; Anticonvulsants; Carbamazepine; Drug Eruptions; Drug Hypersensitivity; Herpesvirus 6, H

2007
Sulfasalazine. Adverse effects and desensitization.
    Digestive diseases and sciences, 1983, Volume: 28, Issue:9

    Topics: Anemia, Hemolytic; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Gastrointestinal D

1983
Sulphasalazine: a 'new' antirheumatic drug.
    British journal of rheumatology, 1984, Volume: 23, Issue:1

    Topics: Agranulocytosis; Anemia; Antibody Formation; Arthritis, Rheumatoid; Bile; Chemical and Drug Induced

1984
Recurrent pericarditis due to mesalamine hypersensitivity: a pediatric case report and review of the literature.
    Journal of pediatric gastroenterology and nutrition, 1998, Volume: 27, Issue:3

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Drug Hypersensitivity; Hum

1998
Pulmonary infiltration and eosinophilia associated with sulfasalazine therapy for ulcerative colitis: a case report and review of literature.
    Internal medicine (Tokyo, Japan), 1992, Volume: 31, Issue:1

    Topics: Colitis, Ulcerative; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Male; Middle Aged;

1992
The safety of sulfasalazine: the gastroenterologists' experience.
    The Journal of rheumatology. Supplement, 1988, Volume: 16

    Topics: Drug Hypersensitivity; Humans; Inflammatory Bowel Diseases; Sulfasalazine

1988
[Drug-induced jaundice].
    Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:9

    Topics: Acetanilides; Aminosalicylic Acids; Benzenesulfonates; Bilirubin; Biological Transport; Cholestasis;

1972

Other Studies

82 other studies available for sulfasalazine and Allergy, Drug

ArticleYear
Checkpoint Inhibition Reduces the Threshold for Drug-Specific T-Cell Priming and Increases the Incidence of Sulfasalazine Hypersensitivity.
    Toxicological sciences : an official journal of the Society of Toxicology, 2022, 02-28, Volume: 186, Issue:1

    Topics: Drug Hypersensitivity; Humans; Incidence; Lymphocyte Activation; Sulfasalazine; Sulfonamides

2022
Drug hypersensitivity syndrome induced by sulfasalazine: A case report.
    Medicine, 2022, Aug-19, Volume: 101, Issue:33

    Topics: Colitis, Ulcerative; Drug Hypersensitivity; Drug Hypersensitivity Syndrome; Exanthema; Humans; Male;

2022
Successful Rapid Oral Desensitization to Sulfasalazine: An 11-Step Protocol.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2021, Dec-01, Volume: 27, Issue:8S

    Topics: Administration, Oral; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Sulfasalazine

2021
High proportion of drug hypersensitivity reactions to sulfasalazine following its use in anti-PD-1-associated inflammatory arthritis.
    Rheumatology (Oxford, England), 2018, 12-01, Volume: 57, Issue:12

    Topics: Aged; Arthritis, Rheumatoid; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Programmed Ce

2018
Hyposensitization trial using salazosulfapyridine in a case of mesalamine intolerance.
    Clinical journal of gastroenterology, 2019, Volume: 12, Issue:6

    Topics: Abdominal Pain; Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative;

2019
Giant cell myocarditis in a patient with a spondyloarthropathy after a drug hypersensitivity reaction.
    The Canadian journal of cardiology, 2013, Volume: 29, Issue:9

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Drug Hypersensitivity; Echocardiography;

2013
Thyroid dysfunction in drug reaction with eosinophilia and systemic symptoms (DRESS): an unusual manifestation of systemic drug hypersensitivity.
    The British journal of dermatology, 2013, Volume: 168, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Drug Hypersensitivity; Eosinophilia; Female; Hum

2013
Drug reaction with eosinophilia and systemic symptoms and thyroiditis: human herpesvirus-6, the possible common link.
    The British journal of dermatology, 2013, Volume: 169, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Hypersensitivity; Eosinophilia; Female; Humans; Sulfas

2013
Drug-induced hypersensitivity syndrome in association with varicella.
    Acta dermato-venereologica, 2015, Volume: 95, Issue:4

    Topics: Aged; Antirheumatic Agents; Chickenpox; Drug Hypersensitivity; Female; Herpesvirus 3, Human; Herpesv

2015
Mesalazine allergy in a boy with ulcerative colitis: clinical usefulness of mucosal biopsy criteria.
    Clinical journal of gastroenterology, 2016, Volume: 9, Issue:5

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Colitis, Ulcerative; Colon; Colonoscopy

2016
Sulfasalazine-Related Hypersensitivity Reactions in Patients With Rheumatic Diseases.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2017, Volume: 23, Issue:2

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Drug Hyp

2017
Lymphoma-like presentation in suspected rheumatoid arthritis due to sulphasalazine hypersensitivity syndrome.
    The New Zealand medical journal, 2008, Jun-20, Volume: 121, Issue:1276

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Diagnosis, Differential; Drug Eruptions; Drug Hy

2008
Fulminant liver failure after vancomycin in a sulfasalazine-induced DRESS syndrome: fatal recurrence after liver transplantation.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2009, Volume: 9, Issue:9

    Topics: Arthritis; Drug Hypersensitivity; Eosinophilia; Fas Ligand Protein; Fatal Outcome; Granzymes; Humans

2009
Sulfasalazine-induced hypersensitivity: a case report of DRESS syndrome.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2009, Volume: 20, Issue:4

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Hypersensitivity; Hepatomegaly; Humans; Mal

2009
Epicutaneous patch testing in drug hypersensitivity syndrome (DRESS).
    Contact dermatitis, 2010, Volume: 62, Issue:1

    Topics: Allopurinol; Amoxicillin; Anticonvulsants; Drug Hypersensitivity; Eosinophilia; Exanthema; Female; H

2010
Cross-reactivity in drug hypersensitivity reactions to sulfasalazine and sulfamethoxazole.
    International archives of allergy and immunology, 2010, Volume: 153, Issue:2

    Topics: Adult; Aged; Anti-Infective Agents; Cross Reactions; Drug Hypersensitivity; Female; Humans; Male; Mi

2010
[Drug-induced lymphadenitis].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 2010, Volume: 39, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; CD3 Complex; Colitis, Ulcerative; Diagnosis, Differe

2010
[DRESS syndrome as a result of sulfasalazine use].
    Nederlands tijdschrift voor geneeskunde, 2010, Volume: 154, Issue:18

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Hypersensitivity; Eosinophilia; Exanthema; Female; Glu

2010
Reactivation of immanent herpes group virus.
    Internal medicine (Tokyo, Japan), 2003, Volume: 42, Issue:2

    Topics: Adult; Antibodies, Viral; Colitis, Ulcerative; Drug Hypersensitivity; Female; Herpesvirus 6, Human;

2003
Salazosulfapyridine induced hypersensitivity syndrome associated with reactivation of humanherpes virus 6.
    Internal medicine (Tokyo, Japan), 2003, Volume: 42, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Viral; Colitis, Ulcerative; Drug Hyperse

2003
DRUG-INDUCED BLOOD DYSCRASIAS. III. HEMOLYTIC ANEMIA.
    JAMA, 1964, Jul-13, Volume: 189

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anemia; Anemia, Hemolytic; Black People; Drug Hypersensit

1964
Drug-induced hypersensitivity syndrome associated with human herpesvirus 6 and cytomegalovirus reactivation.
    The Journal of dermatology, 2005, Volume: 32, Issue:12

    Topics: Aged; Cytomegalovirus; Cytomegalovirus Infections; Drug Hypersensitivity; Exanthema Subitum; Facial

2005
[Drug hypersensitivity syndrome associated with a primary HHV6 infection].
    Annales de dermatologie et de venereologie, 2006, Volume: 133, Issue:2

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Drug Eruption

2006
[A new cause of intra and extrahepatic cholangitis: the drug hypersensitivity syndrome or DRESS (Drug Rash with Eosinophilia and Systemic Symptoms)].
    Gastroenterologie clinique et biologique, 2006, Volume: 30, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cholangitis; Drug Hypersensitivity; Eosinophilia; Ex

2006
[Life-threatening liver failure and severe dyscrasias in blood and lymph nodes caused by sulphasalazine].
    Ugeskrift for laeger, 2006, Sep-25, Volume: 168, Issue:39

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Cell Count; Chemical and Drug Induced Live

2006
[DRESS syndrome to sulfasalzine].
    Revue medicale de Liege, 2006, Volume: 61, Issue:9

    Topics: Adult; Antirheumatic Agents; Drug Hypersensitivity; Female; Humans; Sulfasalazine; Syndrome

2006
[Case of ulcerative colitis associated with drug-induced hypersensitivity syndrome (DIHS) by salazosulfapyridine].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2007, Volume: 104, Issue:1

    Topics: Adult; Betamethasone; Colitis, Ulcerative; Drug Hypersensitivity; Humans; Male; Methylprednisolone;

2007
Sulphasalazine-induced hypersensitivity syndrome: a relapsing disorder and the role of human herpes virus-6.
    European journal of gastroenterology & hepatology, 2007, Volume: 19, Issue:2

    Topics: Adult; Antirheumatic Agents; Drug Hypersensitivity; Female; Herpesvirus 6, Human; Humans; Recurrence

2007
Sulfasalazine-induced hypersensitivity syndrome and hemophagocytic syndrome associated with reactivation of Epstein-Barr virus.
    Clinical rheumatology, 2008, Volume: 27, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug Hypersensitivity; Epstein-Barr Virus Infections; F

2008
Sulphasalazine desensitisation.
    British medical journal (Clinical research ed.), 1981, Jan-10, Volume: 282, Issue:6258

    Topics: Adult; Aged; Child; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Male; Sulfa

1981
Sulfasalazine hepatotoxicity.
    American journal of diseases of children (1960), 1981, Volume: 135, Issue:11

    Topics: Adolescent; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Humans; Liver; Male; Sulf

1981
Sodium cromoglycate in proctitis and ulcerative colitis.
    British medical journal (Clinical research ed.), 1982, Jan-09, Volume: 284, Issue:6309

    Topics: Colitis, Ulcerative; Cromolyn Sodium; Drug Hypersensitivity; Humans; Proctitis; Sulfasalazine

1982
Desensitization of patients with inflammatory bowel disease to sulfasalazine.
    The American journal of medicine, 1982, Volume: 73, Issue:4

    Topics: Colitis, Ulcerative; Crohn Disease; Desensitization, Immunologic; Dose-Response Relationship, Drug;

1982
[40 years of salazosulfapyridine. Is end in sight?].
    Nederlands tijdschrift voor geneeskunde, 1982, Oct-30, Volume: 126, Issue:44

    Topics: Colitis, Ulcerative; Crohn Disease; Drug Hypersensitivity; Humans; Intestinal Absorption; Sulfasalaz

1982
Sulfasalazine and pulmonary infiltrates.
    The American journal of gastroenterology, 1984, Volume: 79, Issue:1

    Topics: Diagnosis, Differential; Drug Hypersensitivity; Humans; Lung Diseases; Male; Middle Aged; Sulfasalaz

1984
Selected individual therapeutic problems in inflammatory bowel disease.
    The American journal of gastroenterology, 1984, Volume: 79, Issue:5

    Topics: Adult; Azathioprine; Campylobacter Infections; Clostridium Infections; Colectomy; Colitis, Ulcerativ

1984
Drug induced lung disease.
    European journal of respiratory diseases. Supplement, 1983, Volume: 126

    Topics: Alveolitis, Extrinsic Allergic; Amiodarone; Antineoplastic Agents; Asthma; Drug Hypersensitivity; Hu

1983
Sulfasalazine: adverse effects.
    Digestive diseases and sciences, 1984, Volume: 29, Issue:8

    Topics: Adolescent; Crohn Disease; Drug Hypersensitivity; Female; Hemiplegia; Humans; Sulfasalazine

1984
[Hypersensitivity reaction to salazosulfapyridine. Value of desensitization after meaningful tests].
    Presse medicale (Paris, France : 1983), 1984, Jul-07, Volume: 13, Issue:28

    Topics: Adult; Aged; Desensitization, Immunologic; Drug Combinations; Drug Hypersensitivity; Female; Glucosa

1984
Sulphasalazine-induced sub-acute hyper-sensitivity pneumonitis.
    Respiratory medicine, 1994, Volume: 88, Issue:2

    Topics: Aged; Bronchi; Drug Hypersensitivity; Female; Humans; Lung; Lung Diseases; Radiography; Sulfasalazin

1994
Sulfasalazine-induced fulminant hepatic failure and necrotizing pancreatitis.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:5

    Topics: Adult; Colitis, Ulcerative; Drug Hypersensitivity; Hepatic Encephalopathy; Humans; Male; Necrosis; P

1994
Desensitization to sulfasalazine.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:3

    Topics: Aminosalicylic Acids; Child; Drug Hypersensitivity; Humans; Inflammatory Bowel Diseases; Stevens-Joh

1993
Sulfasalazine-associated encephalopathy in a patient with Crohn's disease.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:9

    Topics: Acute Disease; Adult; Brain; Brain Diseases; Chemical and Drug Induced Liver Injury; Coma; Crohn Dis

1993
Sulfasalazine-associated encephalopathy in a patient with Crohn's disease.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:10

    Topics: Adult; Brain Diseases; Chemical and Drug Induced Liver Injury; Crohn Disease; Drug Eruptions; Drug H

1993
[Hypersensitivity to 5-aminosalicylic acid. Value of desensitization by oral route].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1997, Volume: 4, Issue:2

    Topics: Administration, Oral; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Child; Crohn Di

1997
Severe hypersensitivity syndrome due to sulfasalazine associated with reactivation of human herpesvirus 6.
    Archives of dermatology, 1998, Volume: 134, Issue:9

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Drug Hypersensitivity; Female; Herpesviridae Infecti

1998
Photosensitivity with sulfasalazopyridine hypersensitivity syndrome.
    Dermatology (Basel, Switzerland), 1999, Volume: 198, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Psoriatic; Dermatitis, Photoallergic; Dru

1999
Late onset hypersensitivity to sulfasalazine in a patient with ankylosing spondylitis.
    Arthritis care and research : the official journal of the Arthritis Health Professions Association, 1999, Volume: 12, Issue:6

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Drug Hypersensitivity; Humans; Hypersensitivity, Del

1999
[Hypersensitivity to mesalazine after severe allergic reaction to sulfasalazine].
    Gastroenterologie clinique et biologique, 2001, Volume: 25, Issue:1

    Topics: Adult; Drug Hypersensitivity; Female; Humans; Male; Mesalamine; Sulfasalazine

2001
Oral pathology quiz #30. Case number two. Erythema multiforme.
    Journal of the New Jersey Dental Association, 2000,Fall, Volume: 71, Issue:4

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Drug Hypersensitivity;

2000
[DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome after sulfasalazine and carmazepine: report of two cases].
    La Revue de medecine interne, 2001, Volume: 22, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants

2001
[Lyell's syndrome caused by Salazopyrine].
    Orvosi hetilap, 1976, Apr-18, Volume: 117, Issue:16

    Topics: Colitis, Ulcerative; Drug Hypersensitivity; Staphylococcal Infections; Stevens-Johnson Syndrome; Sul

1976
Sulfasalazine toxic reactions. Hepatitis, fever, and skin rash with hypocomplementemia and immune complexes.
    JAMA, 1978, Jun-16, Volume: 239, Issue:24

    Topics: Adult; Antigen-Antibody Complex; Chemical and Drug Induced Liver Injury; Complement System Proteins;

1978
Hypersensitivity to salicylazosulfapyridine: renal and hepatic toxic reactions.
    Archives of internal medicine, 1978, Volume: 138, Issue:7

    Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Eosinophilia; Female; Fever; H

1978
Hypersensitivity reaction to sulfasalazine--two reports of the same patient.
    Gastroenterology, 1978, Volume: 75, Issue:6

    Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Kidney Disease

1978
Hypersensitivity reaction to sulfasalazine--another case.
    Gastroenterology, 1978, Volume: 75, Issue:6

    Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Sulfasalazine

1978
Azulfidine- (sulfasalazine-) induced hepatic injury.
    The American journal of digestive diseases, 1978, Volume: 23, Issue:10

    Topics: Adolescent; Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced

1978
Hepatotoxicity of salicylazosulfapyridine: a case report and review of the literature.
    The American journal of gastroenterology, 1979, Volume: 72, Issue:5

    Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Sulfasalazine;

1979
Hypersensitivity reaction to sulfasalazine with severe hepatotoxicity.
    Gastroenterology, 1978, Volume: 75, Issue:1

    Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Inflammatory B

1978
Clinical tolerance to three 5-aminosalicylic acid releasing preparations in patients with inflammatory bowel disease intolerant or allergic to sulphasalazine.
    Alimentary pharmacology & therapeutics, 1992, Volume: 6, Issue:1

    Topics: Aminosalicylic Acids; Drug Hypersensitivity; Female; Humans; Inflammatory Bowel Diseases; Male; Mesa

1992
Sulfasalazine desensitization in children and adolescents with chronic inflammatory bowel disease.
    The American journal of gastroenterology, 1992, Volume: 87, Issue:8

    Topics: Adolescent; Aminosalicylic Acids; Child; Chronic Disease; Desensitization, Immunologic; Diarrhea; Do

1992
Hypersensitivity with hepatotoxicity to mesalazine after hypersensitivity to sulfasalazine.
    Gastroenterology, 1992, Volume: 103, Issue:6

    Topics: Adult; Aminosalicylic Acids; Drug Hypersensitivity; Female; Humans; Liver; Mesalamine; Sulfasalazine

1992
[Desensitization to salazopyrine in rheumatoid polyarthritis].
    Revue du rhumatisme et des maladies osteo-articulaires, 1991, Volume: 58, Issue:2

    Topics: Arthritis, Rheumatoid; Desensitization, Immunologic; Drug Combinations; Drug Hypersensitivity; Femal

1991
Meningitis associated with sulphasalazine in a patient with Sjögren's syndrome and polyarthritis.
    Annals of the rheumatic diseases, 1991, Volume: 50, Issue:9

    Topics: Adult; Arthritis; Drug Hypersensitivity; Female; Humans; Meningitis, Aseptic; Sjogren's Syndrome; Su

1991
Severe immunological reaction induced by sulphasalazine.
    British journal of rheumatology, 1990, Volume: 29, Issue:3

    Topics: Adult; Arthritis; Drug Hypersensitivity; Female; Humans; Sulfasalazine

1990
Immunologic mechanism in sulphasalazine-induced agranulocytosis.
    Acta haematologica, 1990, Volume: 84, Issue:2

    Topics: Adult; Agranulocytosis; Drug Hypersensitivity; Female; Humans; Sulfasalazine

1990
Fatal hypersensitivity reaction to sulphasalazine.
    British journal of rheumatology, 1989, Volume: 28, Issue:3

    Topics: Arthritis; Drug Hypersensitivity; Female; Humans; Middle Aged; Psoriasis; Sulfasalazine

1989
Sulphasalazine desensitisation.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 1989, Volume: 8, Issue:3

    Topics: Adult; Colitis, Ulcerative; Drug Hypersensitivity; Humans; Male; Sulfasalazine

1989
Sulfasalazine hypersensitivity with hepatotoxicity, thrombocytopenia, and erythroid hypoplasia.
    Journal of pediatric gastroenterology and nutrition, 1989, Volume: 9, Issue:2

    Topics: Anemia; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Child; Drug Hypersensitivity;

1989
The value of 5-aminosalicylic acid in inflammatory bowel disease for patients intolerant or allergic to sulphasalazine.
    Postgraduate medical journal, 1985, Volume: 61, Issue:722

    Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Drug Hypersensitivity; Humans; Mesa

1985
Fatal massive hepatic necrosis: a probable hypersensitivity reaction to sulfasalazine.
    The American journal of gastroenterology, 1986, Volume: 81, Issue:3

    Topics: Adolescent; Chemical and Drug Induced Liver Injury; Colitis, Ulcerative; Drug Hypersensitivity; Huma

1986
Hepatotoxicity after treatment with sulfasalazine.
    Postgraduate medicine, 1986, May-01, Volume: 79, Issue:6

    Topics: Adult; Chemical and Drug Induced Liver Injury; Crohn Disease; Drug Eruptions; Drug Hypersensitivity;

1986
Acute sulphasalazine hepatotoxicity.
    Postgraduate medical journal, 1986, Volume: 62, Issue:726

    Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Humans; Male; Sulfasalazine

1986
Ulcerative colitis in West Indian immigrants.
    The Quarterly journal of medicine, 1986, Volume: 59, Issue:229

    Topics: Adolescent; Adult; Child; Colitis, Ulcerative; Drug Hypersensitivity; England; Female; Humans; Male;

1986
[5-aminosalicylic acid treatment of ulcerative colitis during the acute phase in patients resistant or intolerant to salazopyrine].
    Recenti progressi in medicina, 1987, Volume: 78, Issue:2

    Topics: Acute Disease; Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Drug Combinations; Drug Erupt

1987
A case of salicylazosulfapyridine (Salazopyrin)-induced acute pancreatitis with positive lymphocyte stimulation test (LST).
    Gastroenterologia Japonica, 1987, Volume: 22, Issue:2

    Topics: Acute Disease; Adult; Colitis, Ulcerative; Drug Hypersensitivity; Humans; In Vitro Techniques; Lymph

1987
Disodium azodisalicylate and sulfasalazine.
    The American journal of gastroenterology, 1988, Volume: 83, Issue:10

    Topics: Aminosalicylic Acids; Drug Hypersensitivity; Humans; Pancreatitis; Sulfasalazine

1988
Olsalazine and sulfasalazine allergy.
    Journal of clinical gastroenterology, 1988, Volume: 10, Issue:5

    Topics: Aminosalicylic Acids; Drug Hypersensitivity; Humans; Sulfasalazine

1988
[Hypersensitivity reaction to sulfasalazine with a clinical picture similar to mononucleosis].
    Recenti progressi in medicina, 1988, Volume: 79, Issue:9

    Topics: Adult; Colitis, Ulcerative; Diagnosis, Differential; Drug Hypersensitivity; Humans; Infectious Monon

1988
Adverse effects with oral 5-aminosalicyclic acid.
    Journal of clinical gastroenterology, 1988, Volume: 10, Issue:6

    Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Desensitization, Immunologic; Drug Hypersensitivit

1988
Mild ulcerative colitis.
    British medical journal, 1970, Feb-14, Volume: 1, Issue:5693

    Topics: Colitis, Ulcerative; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Sulfasalazine

1970
[Isolated aplastic anemia (acute benign erythroblastopenia of Gasser) in ulcerative colitis].
    Medizinische Klinik, 1970, Apr-17, Volume: 65, Issue:16

    Topics: Acute Disease; Adult; Anemia, Aplastic; Anemia, Macrocytic; Anti-Bacterial Agents; Colitis, Ulcerati

1970