sulfasalazine has been researched along with Allergic Encephalomyelitis in 5 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The sulfasalazine-treated guinea pigs showed a significantly better clinical outcome, as well as a significantly lower histological inflammation score compared with 19 controls." | 1.28 | Suppression of experimental autoimmune encephalomyelitis by sulfasalazine. ( Hoffmann, G; Neu, I; Prosiegel, M; Ruhenstroth-Bauer, G; Vogl, S; Wildfeuer, A, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Evonuk, KS | 1 |
| Baker, BJ | 1 |
| Doyle, RE | 1 |
| Moseley, CE | 1 |
| Sestero, CM | 1 |
| Johnston, BP | 1 |
| De Sarno, P | 1 |
| Tang, A | 1 |
| Gembitsky, I | 1 |
| Hewett, SJ | 1 |
| Weaver, CT | 1 |
| Raman, C | 1 |
| DeSilva, TM | 1 |
| Correale, J | 1 |
| Olsson, T | 1 |
| Björk, J | 1 |
| Smedegård, G | 1 |
| Höjeberg, B | 1 |
| Link, H | 1 |
| Uitdehaag, BM | 1 |
| Polman, CH | 1 |
| de Groot, CJ | 1 |
| Huitinga, I | 1 |
| Dijkstra, CD | 1 |
| Prosiegel, M | 2 |
| Neu, I | 2 |
| Vogl, S | 2 |
| Hoffmann, G | 2 |
| Wildfeuer, A | 2 |
| Ruhenstroth-Bauer, G | 2 |
| Mehlber, L | 1 |
5 other studies available for sulfasalazine and Allergic Encephalomyelitis
| Article | Year |
|---|---|
Inhibition of System Xc(-) Transporter Attenuates Autoimmune Inflammatory Demyelination.
Topics: Amino Acid Transport System y+; Animals; Animals, Newborn; Benzoates; Cell Movement; Central Nervous | 2015 |
Sulfasalazine aggravates experimental autoimmune encephalomyelitis and causes an increase in the number of autoreactive T cells.
Topics: Animals; Brain; CD4 Antigens; CD8 Antigens; Encephalomyelitis, Autoimmune, Experimental; Interferon- | 1991 |
Failure of sulfasalazine to influence experimental autoimmune encephalomyelitis.
Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Humans; Multiple Sclerosis; Neurologic Examina | 1991 |
Suppression of experimental autoimmune encephalomyelitis by sulfasalazine.
Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Female; Guinea Pigs; Sulfasalazine | 1990 |
Suppression of experimental autoimmune encephalomyelitis by sulfasalazine.
Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Female; Guinea Pigs; Multiple Sclerosis; Sulfa | 1989 |