Page last updated: 2024-11-04

sulfasalazine and Agranulocytosis

sulfasalazine has been researched along with Agranulocytosis in 51 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).

Research Excerpts

ExcerptRelevanceReference
"We report the use of granulocyte-macrophage colony stimulating factor (GM-CSF) in a case of rheumatoid arthritis with sulfasalazine induced agranulocytosis, leading to a rapid bone marrow recovery within 7 days."8.78Sulfasalazine induced agranulocytosis treated with granulocyte-macrophage colony stimulating factor. ( de Wolf, JT; Hazenberg, BP; Kuipers, EJ; Vellenga, E, 1992)
"Agranulocytosis is a serious, although rare, adverse reaction to sulfasalazine, which is used to treat inflammatory joint and bowel disease."7.88Sulfasalazine-Induced Agranulocytosis Is Associated With the Human Leukocyte Antigen Locus. ( Axelsson, T; Bengtsson, M; Bondon-Guitton, E; Carvajal, A; Eriksson, N; Hallberg, P; Ibañez, L; Kohnke, H; Kreutz, R; Lucena, MI; Magnusson, PKE; Martin, J; Molokhia, M; Sancho Ponce, E; Wadelius, M; Yue, QY, 2018)
"Agranulocytosis is a rare but serious adverse effect of sulfasalazine treatment."7.81Hyperleucocytosis following G-CSF treatment for sulfasalazine-induced agranulocytosis. ( Chan, K; Farooq, R, 2015)
"To report a case of sulfasalazine-induced agranulocytosis that was successfully treated with granulocyte-colony stimulating factor (G-CSF)."7.68Granulocyte-colony stimulating factor for sulfasalazine-induced agranulocytosis. ( Gales, BJ; Gales, MA, 1993)
"We report a patient with ulcerative colitis in whom agranulocytosis was diagnosed 5 wk after the initiation of sulfasalazine therapy."7.67Sulfasalazine-induced agranulocytosis. ( Blyden, GT; Demirjian, ZN; Isselbacher, KJ; Jacobson, IM; Kelsey, PB, 1985)
"A 55-year-old woman with rheumatoid arthritis in overlap with polymyositis received sulfasalazine for control of synovitis."7.67Cholestasis and fatal agranulocytosis complicating sulfasalazine therapy: case report and review of the literature. ( Mitrane, MP; Seibold, JR; Singh, A, 1986)
"Agranulocytosis is a rare but potentially lethal adverse effect of sulfasalazine."7.67Agranulocytosis associated with sulfasalazine. ( Dery, CL; Schwinghammer, TL, 1988)
"Both DRESS and agranulocytosis were not reported previously with SSZ."5.42Sulfasalazine-induced DRESS and severe agranulocytosis successfully treated by granulocyte colony-stimulating factor. ( Ben Salem, C; Fathallah, N; Hachfi, W; Letaief, A; Rached, S; Slim, R, 2015)
"The incidence of agranulocytosis during the first 30 days was estimated to be 1/2400 patients, while it was 1/700 between Days 31-90 and 1/11200 during Days 91-365."5.28Sulfasalazine associated agranulocytosis in Sweden 1972-1989. Clinical features, and estimation of its incidence. ( Ekman, E; Keisu, M, 1992)
"We report the use of granulocyte-macrophage colony stimulating factor (GM-CSF) in a case of rheumatoid arthritis with sulfasalazine induced agranulocytosis, leading to a rapid bone marrow recovery within 7 days."4.78Sulfasalazine induced agranulocytosis treated with granulocyte-macrophage colony stimulating factor. ( de Wolf, JT; Hazenberg, BP; Kuipers, EJ; Vellenga, E, 1992)
"Agranulocytosis is a rare but serious adverse effect of sulfasalazine treatment."3.81Hyperleucocytosis following G-CSF treatment for sulfasalazine-induced agranulocytosis. ( Chan, K; Farooq, R, 2015)
"We report a patient with ulcerative colitis in whom agranulocytosis was diagnosed 5 wk after the initiation of sulfasalazine therapy."3.67Sulfasalazine-induced agranulocytosis. ( Blyden, GT; Demirjian, ZN; Isselbacher, KJ; Jacobson, IM; Kelsey, PB, 1985)
"A 55-year-old woman with rheumatoid arthritis in overlap with polymyositis received sulfasalazine for control of synovitis."3.67Cholestasis and fatal agranulocytosis complicating sulfasalazine therapy: case report and review of the literature. ( Mitrane, MP; Seibold, JR; Singh, A, 1986)
"A 73-year-old woman developed ulcerative colitis with mesalazine intolerance a year ago."1.91[A case of ulcerative colitis with mesalazine intolerance complicated with agranulocytosis and septic shock during salazosulfapyridine administration]. ( Eizuka, K; Honta, S; Ikehata, A; Inomata, N; Masuo, T; Ono, S; Sekino, Y, 2023)
"Both DRESS and agranulocytosis were not reported previously with SSZ."1.42Sulfasalazine-induced DRESS and severe agranulocytosis successfully treated by granulocyte colony-stimulating factor. ( Ben Salem, C; Fathallah, N; Hachfi, W; Letaief, A; Rached, S; Slim, R, 2015)
"Drug-induced agranulocytosis (DIA) is a potentially fatal disorder."1.31Hematopoietic growth factors in drug-induced agranulocytosis. ( Pavithran, K; Thomas, M, 2002)
"Thirty-nine patients reacted with agranulocytosis, while 75 patients had been treated for a minimum of 3 months without haematological side-effects."1.31Polymorphisms of NAT2 in relation to sulphasalazine-induced agranulocytosis. ( Rane, A; Stjernberg, E; Wadelius, M; Wiholm, BE, 2000)
"Sulphasalazine-induced agranulocytosis is a rare but potentially life threatening complication."1.29Treatment of sulphasalazine-induced agranulocytosis with granulocyte macrophage-colony stimulating factor. ( Cook, MK; Dorrance, H; Rainey, JB; Roddie, P, 1995)
"The relative risk for agranulocytosis during sulphasalazine treatment was calculated to be 107 and 123 by the spontaneous reporting system and the case-control study, respectively."1.28Comparing risk estimates of sulphonamide-induced agranulocytosis from the Swedish Drug Monitoring System and a case-control study. ( Ekman, E; Keisu, M; Wiholm, BE, 1992)
"GM-CSF treatment for severe agranulocytosis deserves further investigation."1.28Treatment of drug-induced agranulocytosis with recombinant GM-CSF. ( Jonson, B; Kanerud, L; Palmblad, J, 1990)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-199026 (50.98)18.7374
1990's15 (29.41)18.2507
2000's5 (9.80)29.6817
2010's4 (7.84)24.3611
2020's1 (1.96)2.80

Authors

AuthorsStudies
Ikehata, A1
Honta, S1
Sekino, Y1
Masuo, T1
Eizuka, K1
Inomata, N1
Ono, S1
Wadelius, M2
Eriksson, N1
Kreutz, R1
Bondon-Guitton, E1
Ibañez, L1
Carvajal, A1
Lucena, MI1
Sancho Ponce, E1
Molokhia, M1
Martin, J1
Axelsson, T1
Kohnke, H1
Yue, QY1
Magnusson, PKE1
Bengtsson, M1
Hallberg, P1
Fathallah, N1
Slim, R1
Rached, S1
Hachfi, W1
Letaief, A1
Ben Salem, C1
Chan, K1
Farooq, R1
Kato, M1
Kano, Y1
Sato, Y1
Shiohara, T1
Pavithran, K1
Thomas, M1
EVANS, RS1
FORD, WP1
VINGGARD, HE1
THIRKETTLE, JL1
GOUGH, KR1
READ, AE1
PANITZ, F1
ROTH, DA1
LINDERT, ME1
Avery, JK1
Miller, B1
Maddocks, JL1
Slater, DN1
Wheelan, KR1
Cooper, B1
Stone, MJ1
Søndergaard, JO1
Stage, JG1
Sprechler, M1
Hutchinson, D1
Wyld, PJ1
Pullar, T1
Capell, HA1
Danielson, DA1
Douglas, SW1
Herzog, P1
Jick, H1
Porter, JB1
Gales, BJ1
Gales, MA1
te Gussinklo, JT1
Rospond, RM1
Glowacki, RC1
Mailliard, JA1
Canvin, JM1
el-Gabalawy, HS1
Chalmers, IM1
Crawford, GP1
Laurence, BL1
Roddie, P1
Dorrance, H1
Cook, MK1
Rainey, JB1
Murphy, PT2
Casey, MC1
Nakamura, K1
Takeshima, F1
Shiozawa, K1
Furusu, H1
Tomonaga, M1
Isomoto, H1
Ohmagari, K1
Mizuta, Y1
Murase, K1
Kohno, S1
van Rijthoven, AW1
Stjernberg, E1
Wiholm, BE2
Rane, A1
Kuipers, EJ1
Vellenga, E1
de Wolf, JT1
Hazenberg, BP1
Keisu, M2
Ekman, E2
Matsubayashi, Y1
Izumi, Y1
Mori, Y1
Itoh, K1
Morioka, A1
Tatsuta, H1
Hashimoto, A1
Kotera, T1
Itoh, A1
Jo, I1
Victorino, RM1
Maria, VA1
de Deus, J1
O'Donnell, JR1
Palmblad, J1
Jonson, B1
Kanerud, L1
Pointud, P1
Cauhape, P1
Favreau, A1
Guillemin, F1
Aussedat, R1
Guerci, A1
Lederlin, P1
Trechot, P1
Pourel, J1
Jacobson, IM1
Kelsey, PB1
Blyden, GT1
Demirjian, ZN1
Isselbacher, KJ1
Farr, M1
Symmons, DP1
Blake, DR1
Bacon, PA1
Mitrane, MP1
Singh, A1
Seibold, JR1
Dery, CL1
Schwinghammer, TL1
Levi, S1
Liberman, M1
Levi, AJ1
Bjarnason, I1
Kvarstein, G1
Hovdenak, N1
Das, KM1
Eastwood, MA1
McManus, JP1
Sircus, W1
Cochrane, P1
Atkins, P1
Ehsanullah, S1
Darling, VE1
Collins, JR1
Marstein, S1
Jamshidi, K1
Arlander, T1
Garcia, MC1
Windschitl, HW1
Swaim, WR1

Reviews

2 reviews available for sulfasalazine and Agranulocytosis

ArticleYear
Sulphasalazine: a 'new' antirheumatic drug.
    British journal of rheumatology, 1984, Volume: 23, Issue:1

    Topics: Agranulocytosis; Anemia; Antibody Formation; Arthritis, Rheumatoid; Bile; Chemical and Drug Induced

1984
Sulfasalazine induced agranulocytosis treated with granulocyte-macrophage colony stimulating factor.
    The Journal of rheumatology, 1992, Volume: 19, Issue:4

    Topics: Adult; Agranulocytosis; Arthritis, Rheumatoid; Bone Marrow; Female; Granulocyte-Macrophage Colony-St

1992

Other Studies

49 other studies available for sulfasalazine and Agranulocytosis

ArticleYear
[A case of ulcerative colitis with mesalazine intolerance complicated with agranulocytosis and septic shock during salazosulfapyridine administration].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2023, Volume: 120, Issue:9

    Topics: Aged; Agranulocytosis; Colitis, Ulcerative; Female; Humans; Mesalamine; Shock, Septic; Sulfasalazine

2023
Sulfasalazine-Induced Agranulocytosis Is Associated With the Human Leukocyte Antigen Locus.
    Clinical pharmacology and therapeutics, 2018, Volume: 103, Issue:5

    Topics: Adult; Aged; Agranulocytosis; Alleles; Case-Control Studies; Female; Genome-Wide Association Study;

2018
Sulfasalazine-induced DRESS and severe agranulocytosis successfully treated by granulocyte colony-stimulating factor.
    International journal of clinical pharmacy, 2015, Volume: 37, Issue:4

    Topics: Adult; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Drug Hypersens

2015
Hyperleucocytosis following G-CSF treatment for sulfasalazine-induced agranulocytosis.
    BMJ case reports, 2015, Jul-15, Volume: 2015

    Topics: Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Female; Filgrastim; Granulocyte

2015
Severe Agranulocytosis in Two Patients with Drug-induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms.
    Acta dermato-venereologica, 2016, 08-23, Volume: 96, Issue:6

    Topics: Aged; Aged, 80 and over; Agranulocytosis; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Anti

2016
Hematopoietic growth factors in drug-induced agranulocytosis.
    The Journal of the Association of Physicians of India, 2002, Volume: 50, Issue:5

    Topics: Adolescent; Adult; Agranulocytosis; Chlorpromazine; Dapsone; Dipyrone; Female; Granulocyte-Macrophag

2002
Studies of the bone marrow in immunological granulocytopenia; following administration of salicylazosulfapyridine.
    A.M.A. archives of internal medicine, 1958, Volume: 101, Issue:2

    Topics: Agranulocytosis; Anemia, Myelophthisic; Bone Marrow; Colitis; Colitis, Ulcerative; Sulfanilamide; Su

1958
[3 cases of medicamentous agranulocytosis: Largactil, Cibalgin, Salazopyrine].
    Ugeskrift for laeger, 1962, Feb-02, Volume: 124

    Topics: Agranulocytosis; Aminopyrine; Barbiturates; Chlorpromazine; Drug Combinations; Glucosamine; Humans;

1962
Agranulocytosis associated with sulphasalazine ('Salazopyrin') therapy.
    Lancet (London, England), 1963, Jun-29, Volume: 1, Issue:7296

    Topics: Agranulocytosis; Humans; Sulfanilamide; Sulfanilamides; Sulfasalazine; Sulfonamides

1963
AGRANULOCYTOSIS DUE TO ADMINISTRATION OF SALICYLAZOSULFAPYRADINE (AZULFIDINE).
    Medical bulletin of the U. S. Army, Europe. United States. Army, Europe. Medical Division, 1963, Volume: 20

    Topics: Agranulocytosis; Colitis; Colitis, Ulcerative; Humans; Sulfasalazine; Toxicology

1963
A fatal case of azulfidine-induced agranulocytosis.
    Gastroenterology, 1959, Volume: 37

    Topics: Agranulocytosis; Humans; Sulfanilamide; Sulfanilamides; Sulfasalazine; Sulfonamides

1959
Loss prevention case of the month. Monitoring remains critical.
    Tennessee medicine : journal of the Tennessee Medical Association, 2004, Volume: 97, Issue:1

    Topics: Acetaminophen; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Clini

2004
[Side effects of salicylazosulfapyridine therapy].
    Deutsche medizinische Wochenschrift (1946), 1980, Nov-14, Volume: 105, Issue:46

    Topics: Agranulocytosis; Colitis, Ulcerative; Crohn Disease; Exanthema; Fever; Humans; Sulfasalazine

1980
Toxic epidermal necrolysis, agranulocytosis and erythroid hypoplasia associated with sulphasalazine.
    Journal of the Royal Society of Medicine, 1980, Volume: 73, Issue:8

    Topics: Adult; Agranulocytosis; Autopsy; Bone Marrow Diseases; Colitis, Ulcerative; Humans; Male; Stevens-Jo

1980
Multiple haematologic abnormalities associated with sulfasalazine.
    Annals of internal medicine, 1982, Volume: 97, Issue:5

    Topics: Adult; Agranulocytosis; Anemia, Aplastic; Hematologic Diseases; Humans; Male; Myeloproliferative Dis

1982
[Agranulocytosis in patients with ulcerative colitis treated with salazosulphapyridine].
    Ugeskrift for laeger, 1983, Jul-18, Volume: 145, Issue:29

    Topics: Agranulocytosis; Colitis, Ulcerative; Humans; Male; Middle Aged; Sulfasalazine

1983
Sulphasalazine induced agranulocytosis.
    The New Zealand medical journal, 1983, Jul-13, Volume: 96, Issue:735

    Topics: Acetylation; Adult; Agranulocytosis; Diarrhea; Humans; Male; Middle Aged; Phenotype; Sulfasalazine

1983
Drug-induced blood disorders.
    JAMA, 1984, Dec-21, Volume: 252, Issue:23

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Anemia, Hemolytic; Child; Female; Hematologic Diseases; Hu

1984
Granulocyte-colony stimulating factor for sulfasalazine-induced agranulocytosis.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:9

    Topics: Aged; Aged, 80 and over; Agranulocytosis; Female; Granulocyte Colony-Stimulating Factor; Humans; Inj

1993
[Hematopoietic growth factors as supportive treatment in agranulocytosis as a result of administered drugs].
    Nederlands tijdschrift voor geneeskunde, 1994, Jan-08, Volume: 138, Issue:2

    Topics: Aged; Agranulocytosis; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Sulfasalazi

1994
Sargramostim for sulfasalazine-induced agranulocytosis.
    Clinical pharmacy, 1993, Volume: 12, Issue:3

    Topics: Adolescent; Agranulocytosis; Drug Eruptions; Fever; Granulocyte-Macrophage Colony-Stimulating Factor

1993
Fatal agranulocytosis with sulfasalazine therapy in rheumatoid arthritis.
    The Journal of rheumatology, 1993, Volume: 20, Issue:5

    Topics: Aged; Agranulocytosis; Arthritis, Rheumatoid; Female; Humans; Sulfasalazine

1993
Sulphasalazine-induced agranulocytosis successfully treated with filgrastim.
    Australian and New Zealand journal of medicine, 1996, Volume: 26, Issue:2

    Topics: Adolescent; Agranulocytosis; Anti-Inflammatory Agents; Female; Filgrastim; Granulocyte Colony-Stimul

1996
Treatment of sulphasalazine-induced agranulocytosis with granulocyte macrophage-colony stimulating factor.
    Alimentary pharmacology & therapeutics, 1995, Volume: 9, Issue:6

    Topics: Adult; Agranulocytosis; Colitis, Ulcerative; Gastrointestinal Agents; Granulocyte-Macrophage Colony-

1995
Sulphasalazine induced agranulocytosis revisited.
    Irish medical journal, 1998, Volume: 91, Issue:6

    Topics: Agranulocytosis; Granulocyte Colony-Stimulating Factor; Humans; Male; Middle Aged; Sulfasalazine

1998
[Remission for a patient with ulcerative colitis after agranulocytosis by the side effect of salazosulfapyridine].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2000, Jan-10, Volume: 89, Issue:1

    Topics: Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Humans; Male; Middle

2000
[Pharmacotherapy of patients with (early) rheumatoid arthritis].
    Nederlands tijdschrift voor geneeskunde, 2000, Mar-11, Volume: 144, Issue:11

    Topics: Agranulocytosis; Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Humans; Methotrexate; Su

2000
Polymorphisms of NAT2 in relation to sulphasalazine-induced agranulocytosis.
    Pharmacogenetics, 2000, Volume: 10, Issue:1

    Topics: Acetylation; Adolescent; Adult; Aged; Aged, 80 and over; Agranulocytosis; Alleles; Anti-Inflammatory

2000
Comparing risk estimates of sulphonamide-induced agranulocytosis from the Swedish Drug Monitoring System and a case-control study.
    European journal of clinical pharmacology, 1992, Volume: 43, Issue:3

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Case-Control Studies; Drug Monitoring; Female; Humans; Mal

1992
Sulfasalazine associated agranulocytosis in Sweden 1972-1989. Clinical features, and estimation of its incidence.
    European journal of clinical pharmacology, 1992, Volume: 43, Issue:3

    Topics: Agranulocytosis; Bone Marrow; Cohort Studies; Drug Monitoring; Drug Prescriptions; Humans; Risk; Sul

1992
[Salazopyrine-induced agranulocytosis: clinical picture and incidence].
    Lakartidningen, 1991, Mar-20, Volume: 88, Issue:12

    Topics: Adult; Agranulocytosis; Drug Combinations; Glucosamine; Humans; Incidence; Middle Aged; Prognosis; S

1991
[Salicylazosulfapyridine-induced agranulocytosis in a patient with ulcerative colitis, successfully treated with granulocyte colony-stimulating factor].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1991, Volume: 88, Issue:1

    Topics: Adult; Agranulocytosis; Bone Marrow; Colitis, Ulcerative; Female; Granulocyte Colony-Stimulating Fac

1991
Immunologic mechanism in sulphasalazine-induced agranulocytosis.
    Acta haematologica, 1990, Volume: 84, Issue:2

    Topics: Adult; Agranulocytosis; Drug Hypersensitivity; Female; Humans; Sulfasalazine

1990
Sulphasalazine induced agranulocytosis in a patient with rheumatoid arthritis.
    Irish journal of medical science, 1990, Volume: 159, Issue:6

    Topics: Adult; Agranulocytosis; Arthritis, Rheumatoid; Female; Humans; Sulfasalazine

1990
Treatment of drug-induced agranulocytosis with recombinant GM-CSF.
    Journal of internal medicine, 1990, Volume: 228, Issue:5

    Topics: Agranulocytosis; Arthritis, Rheumatoid; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Ma

1990
[Agranulocytosis in rheumatoid polyarthritis treated with sulfasalazine].
    Revue du rhumatisme et des maladies osteo-articulaires, 1989, Volume: 56, Issue:7

    Topics: Agranulocytosis; Arthritis, Rheumatoid; Humans; Male; Middle Aged; Sulfasalazine

1989
Fatal agranulocytosis in sulfasalazine treated rheumatoid arthritis.
    The Journal of rheumatology, 1989, Volume: 16, Issue:8

    Topics: Agranulocytosis; Arthritis, Rheumatoid; Female; Humans; Middle Aged; Neutropenia; Sulfasalazine

1989
Sulfasalazine-induced agranulocytosis.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:2

    Topics: Agranulocytosis; Bone Marrow Examination; Colitis, Ulcerative; Humans; Male; Middle Aged; Sulfasalaz

1985
Neutropenia in patients with inflammatory arthritis treated with sulphasalazine.
    Annals of the rheumatic diseases, 1986, Volume: 45, Issue:9

    Topics: Acute Disease; Adult; Agranulocytosis; Arthritis; Humans; Leukopenia; Male; Middle Aged; Neutropenia

1986
Cholestasis and fatal agranulocytosis complicating sulfasalazine therapy: case report and review of the literature.
    The Journal of rheumatology, 1986, Volume: 13, Issue:5

    Topics: Agranulocytosis; Arthritis, Rheumatoid; Cholestasis, Intrahepatic; Female; Humans; Middle Aged; Myos

1986
Agranulocytosis associated with sulfasalazine.
    Drug intelligence & clinical pharmacy, 1988, Volume: 22, Issue:2

    Topics: Aged; Agranulocytosis; Female; Humans; Leukocyte Count; Sulfasalazine; Time Factors

1988
Reversible congenital neutropenia associated with maternal sulphasalazine therapy.
    European journal of pediatrics, 1988, Volume: 148, Issue:2

    Topics: Adult; Agranulocytosis; Female; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Neutropenia;

1988
[Granulocytopenia in treatment with salazopyrin].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1988, Nov-20, Volume: 108, Issue:32

    Topics: Aged; Agranulocytosis; Colitis, Ulcerative; Humans; Male; Middle Aged; Sulfasalazine

1988
Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype.
    The New England journal of medicine, 1973, Sep-06, Volume: 289, Issue:10

    Topics: Acetylation; Agranulocytosis; Aminosalicylic Acids; Anemia, Hemolytic; Colitis, Ulcerative; Crohn Di

1973
Agranulocytosis associated with sulphasalazine therapy.
    Postgraduate medical journal, 1973, Volume: 49, Issue:575

    Topics: Acetylation; Aged; Agranulocytosis; Antibodies; Female; Humans; Leukocytes; Sulfasalazine; Time Fact

1973
Drug agranulocytosis. A case study.
    Nursing times, 1965, Sep-03, Volume: 61, Issue:36

    Topics: Agranulocytosis; Female; Humans; Middle Aged; Nursing Care; Sulfasalazine

1965
Adverse reactions to salicylazosulfapyridine (azulfidine) in the treatment of ulcerative colitis.
    Southern medical journal, 1968, Volume: 61, Issue:4

    Topics: Adult; Agranulocytosis; Colitis, Ulcerative; Dermatitis; Exanthema; Headache; Hematologic Diseases;

1968
[Agranulocytosis during treatment with salicylazosulfapyridine (Salazopyrin)].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1969, Oct-01, Volume: 89, Issue:19

    Topics: Agranulocytosis; Blood Cell Count; Enterocolitis, Pseudomembranous; Humans; Male; Middle Aged; Sulfa

1969
Azulfidine agranulocytosis with bone marrow, megakaryocytosis, histiocytosis and plasmacytosis.
    Minnesota medicine, 1972, Volume: 55, Issue:6

    Topics: Aged; Agranulocytosis; Bone Marrow Examination; Humans; Leukocyte Count; Lymphatic Diseases; Male; M

1972