sulfasalazine has been researched along with Adenomatous Polyposis Coli in 1 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Adenomatous Polyposis Coli: A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lynch, PM | 1 |
| Morris, JS | 1 |
| Wen, S | 1 |
| Advani, SM | 1 |
| Ross, W | 1 |
| Chang, GJ | 1 |
| Rodriguez-Bigas, M | 1 |
| Raju, GS | 1 |
| Ricciardiello, L | 1 |
| Iwama, T | 1 |
| Rossi, BM | 1 |
| Pellise, M | 1 |
| Stoffel, E | 1 |
| Wise, PE | 1 |
| Bertario, L | 1 |
| Saunders, B | 1 |
| Burt, R | 1 |
| Belluzzi, A | 1 |
| Ahnen, D | 1 |
| Matsubara, N | 1 |
| Bülow, S | 1 |
| Jespersen, N | 1 |
| Clark, SK | 1 |
| Erdman, SH | 1 |
| Markowitz, AJ | 1 |
| Bernstein, I | 1 |
| De Haas, N | 1 |
| Syngal, S | 1 |
| Moeslein, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Sirolimus for Cowden Syndrome With Colon Polyposis[NCT04094675] | Phase 2 | 10 participants (Anticipated) | Interventional | 2019-09-16 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 other study available for sulfasalazine and Adenomatous Polyposis Coli
| Article | Year |
|---|---|
A proposed staging system and stage-specific interventions for familial adenomatous polyposis.
Topics: Adenomatous Polyposis Coli; Colectomy; Colonoscopy; Colorectal Surgery; Consensus; Endoscopic Mucosa | 2016 |