sulfasalazine has been researched along with Ache in 25 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bucillamine (Buc), developed in Japan, is a disease-modifying antirheumatic drug (DMARD) which has been used to treat numerous patients with rheumatoid arthritis (RA) in Japan and Korea with favorable results." | 9.14 | A comparative study of the effects of bucillamine and salazosulfapyridine in the treatment of rheumatoid arthritis. ( Abe, M; Kinoshita, M; Nakajima, M; Ohara, H; Ueda, N, 2009) |
| "Bucillamine (Buc) is a disease-modifying antirheumatic drug (DMARD) developed in Japan, which has been used as one of the first-line DMARDs for the treatment of rheumatoid arthritis (RA) in Japan." | 9.12 | Efficacy profile of bucillamine in rheumatoid arthritis patients in a large observational cohort study, IORRA. ( Hara, M; Inoue, E; Iwatani, M; Kamatani, N; Nakajima, A; Nakamura, T; Tomatsu, T; Yamanaka, H, 2006) |
| "One hundred eight-six patients with active rheumatoid arthritis were evaluated in a double-blind, randomized study that compared treatment with sulfasalazine (SSZ) (2 mg/day), gold sodium thiomalate (GST) (50 mg/week), and placebo (PBO)." | 9.06 | A controlled trial comparing sulfasalazine, gold sodium thiomalate, and placebo in rheumatoid arthritis. ( Clegg, DO; Dahl, SL; Luggen, ME; Michaels, RM; Oglesby, T; Schlegel, S; Ward, JR; Weisman, MH; Williams, HJ; Willkens, RF, 1988) |
| " Immunodeficient mice were inoculated intrafemorally with the human breast adenocarcinoma cell line MDA-MB-231, then treated 14days later via mini-osmotic pumps inserted intraperitoneally with sulfasalazine, (S)-4-carboxyphenylglycine, or vehicle." | 7.80 | Inhibition of breast cancer-cell glutamate release with sulfasalazine limits cancer-induced bone pain. ( Seidlitz, EP; Singh, G; Ungard, RG, 2014) |
| "Agastache mexicana is a popular plant of great demand in folk medicine, essentially due to its calming properties and for alleviating arthritic, muscular and abdominal pain." | 5.62 | Limonene from Agastache mexicana essential oil produces antinociceptive effects, gastrointestinal protection and improves experimental ulcerative colitis. ( Adriana Estrella, GR; Alberto, HL; Azucena, CV; Francisco Javier, LM; María Eva, GT; María Guadalupe, VD; Noé, AV; Sandra, OS, 2021) |
| "Bucillamine (Buc), developed in Japan, is a disease-modifying antirheumatic drug (DMARD) which has been used to treat numerous patients with rheumatoid arthritis (RA) in Japan and Korea with favorable results." | 5.14 | A comparative study of the effects of bucillamine and salazosulfapyridine in the treatment of rheumatoid arthritis. ( Abe, M; Kinoshita, M; Nakajima, M; Ohara, H; Ueda, N, 2009) |
| "Bucillamine (Buc) is a disease-modifying antirheumatic drug (DMARD) developed in Japan, which has been used as one of the first-line DMARDs for the treatment of rheumatoid arthritis (RA) in Japan." | 5.12 | Efficacy profile of bucillamine in rheumatoid arthritis patients in a large observational cohort study, IORRA. ( Hara, M; Inoue, E; Iwatani, M; Kamatani, N; Nakajima, A; Nakamura, T; Tomatsu, T; Yamanaka, H, 2006) |
| "One hundred eight-six patients with active rheumatoid arthritis were evaluated in a double-blind, randomized study that compared treatment with sulfasalazine (SSZ) (2 mg/day), gold sodium thiomalate (GST) (50 mg/week), and placebo (PBO)." | 5.06 | A controlled trial comparing sulfasalazine, gold sodium thiomalate, and placebo in rheumatoid arthritis. ( Clegg, DO; Dahl, SL; Luggen, ME; Michaels, RM; Oglesby, T; Schlegel, S; Ward, JR; Weisman, MH; Williams, HJ; Willkens, RF, 1988) |
| " Immunodeficient mice were inoculated intrafemorally with the human breast adenocarcinoma cell line MDA-MB-231, then treated 14days later via mini-osmotic pumps inserted intraperitoneally with sulfasalazine, (S)-4-carboxyphenylglycine, or vehicle." | 3.80 | Inhibition of breast cancer-cell glutamate release with sulfasalazine limits cancer-induced bone pain. ( Seidlitz, EP; Singh, G; Ungard, RG, 2014) |
| "Sulfasalazine is a safe and effective drug in the short term treatment of AS." | 3.76 | Meta-analysis of sulfasalazine in ankylosing spondylitis. ( Atra, E; Ferraz, MB; Goldsmith, CH; Tugwell, P, 1990) |
| "Management of ankylosing spondylitis (AS) is challenged by the progressive nature of the disease." | 2.41 | Conventional treatments for ankylosing spondylitis. ( Brandt, J; Dijkmans, B; Dougados, M; Khan, M; Maksymowych, W; van der Linden, S, 2002) |
| "Sulfasalazine and JLC were administrated orally and initialized 6 h after TNBS enema, once a day for seven consecutive days." | 1.62 | Jiaolong capsule protects SD rats against 2,4,6-trinitrobenzene sulfonic acid induced colitis. ( Chen, G; Diao, F; Dong, M; Li, Y; Lin, W; Liu, T; Liu, Y; Mei, Q; Ruan, Y; Sun, Y; Tang, T; Zhou, H, 2021) |
| "Agastache mexicana is a popular plant of great demand in folk medicine, essentially due to its calming properties and for alleviating arthritic, muscular and abdominal pain." | 1.62 | Limonene from Agastache mexicana essential oil produces antinociceptive effects, gastrointestinal protection and improves experimental ulcerative colitis. ( Adriana Estrella, GR; Alberto, HL; Azucena, CV; Francisco Javier, LM; María Eva, GT; María Guadalupe, VD; Noé, AV; Sandra, OS, 2021) |
| "We diagnosed late onset spondyloarthropathy according to clinic and radiographic findings." | 1.38 | Late onset spondyloarthropathy mimicking polymyalgia rheumatica. ( Altındağ, O; Aydeniz, A; Gürsoy, S; Oğüt, E, 2012) |
| "Sulfasalazine treatment also increased inosine levels in sciatic nerves of diabetic rats." | 1.35 | Sulfasalazine blocks the development of tactile allodynia in diabetic rats. ( Berti-Mattera, LN; Kern, TS; Mitchell, R; Nemet, I; Siegel, RE, 2008) |
| "To define a possible association between familial Mediterranean fever (FMF) and seronegative spondyloarthropathy (SNSA) and to study features of SNSA in FMF patients, we screened for the presence and manifestations of SNSA in 3,000 FMF patients attending the National Center for FMF in our institution." | 1.30 | Seronegative spondyloarthropathy in familial Mediterranean fever. ( Langevitz, P; Livneh, A; Pras, M; Shemer, J; Zemer, D, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (16.00) | 18.7374 |
| 1990's | 10 (40.00) | 18.2507 |
| 2000's | 6 (24.00) | 29.6817 |
| 2010's | 3 (12.00) | 24.3611 |
| 2020's | 2 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y | 1 |
| Sun, Y | 1 |
| Diao, F | 1 |
| Ruan, Y | 1 |
| Chen, G | 1 |
| Tang, T | 1 |
| Liu, Y | 1 |
| Zhou, H | 1 |
| Lin, W | 1 |
| Dong, M | 1 |
| Liu, T | 1 |
| Mei, Q | 1 |
| Adriana Estrella, GR | 1 |
| María Eva, GT | 1 |
| Alberto, HL | 1 |
| María Guadalupe, VD | 1 |
| Azucena, CV | 1 |
| Sandra, OS | 1 |
| Noé, AV | 1 |
| Francisco Javier, LM | 1 |
| Ungard, RG | 1 |
| Seidlitz, EP | 1 |
| Singh, G | 1 |
| Agarwal, NN | 1 |
| Patil, D | 1 |
| Nagendra, S | 1 |
| Jadhav, SM | 1 |
| Berti-Mattera, LN | 1 |
| Kern, TS | 1 |
| Siegel, RE | 1 |
| Nemet, I | 1 |
| Mitchell, R | 1 |
| Nakajima, M | 1 |
| Ueda, N | 1 |
| Ohara, H | 1 |
| Abe, M | 1 |
| Kinoshita, M | 1 |
| Aydeniz, A | 1 |
| Altındağ, O | 1 |
| Oğüt, E | 1 |
| Gürsoy, S | 1 |
| Ferraccioli, GF | 1 |
| Gremese, E | 1 |
| Tomietto, P | 1 |
| Favret, G | 1 |
| Damato, R | 1 |
| Di Poi, E | 1 |
| Dougados, M | 1 |
| Dijkmans, B | 1 |
| Khan, M | 1 |
| Maksymowych, W | 1 |
| van der Linden, S | 1 |
| Brandt, J | 1 |
| Iwatani, M | 1 |
| Inoue, E | 1 |
| Nakamura, T | 1 |
| Nakajima, A | 1 |
| Hara, M | 1 |
| Tomatsu, T | 1 |
| Kamatani, N | 1 |
| Yamanaka, H | 1 |
| Strum, WB | 1 |
| van der Heijde, DM | 2 |
| van 't Hof, M | 1 |
| van Riel, PL | 1 |
| van de Putte, LB | 1 |
| Nicassio, PM | 1 |
| Radojevic, V | 1 |
| Weisman, MH | 2 |
| Culbertson, AL | 1 |
| Lewis, C | 1 |
| Clemmey, P | 1 |
| Fraser, SM | 1 |
| Hopkins, R | 2 |
| Hunter, JA | 1 |
| Neumann, V | 1 |
| Capell, HA | 1 |
| Bird, HA | 1 |
| Taggart, A | 1 |
| Gardiner, P | 1 |
| McEvoy, F | 1 |
| Bird, H | 1 |
| Collange, C | 1 |
| Brantus, JF | 1 |
| Sidot, C | 1 |
| Meunier, PJ | 1 |
| Egsmose, C | 1 |
| Hansen, TM | 1 |
| Andersen, LS | 1 |
| Beier, JM | 1 |
| Christensen, L | 1 |
| Ejstrup, L | 1 |
| Peters, ND | 1 |
| Langevitz, P | 1 |
| Livneh, A | 1 |
| Zemer, D | 1 |
| Shemer, J | 1 |
| Pras, M | 1 |
| Coinde, E | 1 |
| David, L | 1 |
| Cottalorda, J | 1 |
| Allard, D | 1 |
| Bost, M | 1 |
| Lucht, F | 1 |
| Stéphan, JL | 1 |
| Corkill, MM | 1 |
| Jobanputra, P | 1 |
| Gibson, T | 1 |
| Macfarlane, DG | 1 |
| Farr, M | 1 |
| Kitas, GD | 1 |
| Waterhouse, L | 1 |
| Jubb, R | 1 |
| Felix-Davies, D | 1 |
| Bacon, PA | 1 |
| Ferraz, MB | 1 |
| Tugwell, P | 1 |
| Goldsmith, CH | 1 |
| Atra, E | 1 |
| Hanan, IM | 1 |
| Kirsner, JB | 1 |
| Williams, HJ | 1 |
| Ward, JR | 1 |
| Dahl, SL | 1 |
| Clegg, DO | 1 |
| Willkens, RF | 1 |
| Oglesby, T | 1 |
| Schlegel, S | 1 |
| Michaels, RM | 1 |
| Luggen, ME | 1 |
| Tumen, HJ | 1 |
2 reviews available for sulfasalazine and Ache
| Article | Year |
|---|---|
Conventional treatments for ankylosing spondylitis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Azathioprine; Dipho | 2002 |
Meta-analysis of sulfasalazine in ankylosing spondylitis.
Topics: Double-Blind Method; Humans; Meta-Analysis as Topic; Outcome and Process Assessment, Health Care; Pa | 1990 |
12 trials available for sulfasalazine and Ache
| Article | Year |
|---|---|
A comparative study of the effects of bucillamine and salazosulfapyridine in the treatment of rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Cysteine; Drug Therapy, Combination | 2009 |
Analysis of improvements, full responses, remission and toxicity in rheumatoid patients treated with step-up combination therapy (methotrexate, cyclosporin A, sulphasalazine) or monotherapy for three years.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; | 2002 |
Efficacy profile of bucillamine in rheumatoid arthritis patients in a large observational cohort study, IORRA.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cohort Studies; Cysteine; Drug Thera | 2006 |
Validity of single variables and indices to measure disease activity in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Azathioprine; Blood Sedimentation; C-Reactive Protein; Disabled Persons; Hemo | 1993 |
The role of helplessness in the response to disease modifying drugs in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Behavior; Cognition; Disability Evaluation; Female; Gold; Helple | 1993 |
Sulphasalazine in the management of psoriatic arthritis.
Topics: Adolescent; Adult; Aged; Arthritis, Psoriatic; Blood Sedimentation; Female; Humans; Joints; Male; Mi | 1993 |
Which is the active moiety of sulfasalazine in ankylosing spondylitis? A randomized, controlled study.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Binding Site | 1996 |
Limited effect of sulphasalazine treatment in reactive arthritis. A randomised double blind placebo controlled trial.
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Reactive; Blood Sedimentation; Double-Blind Method; Fema | 1997 |
A controlled trial of sulphasalazine treatment of chronic ankylosing spondylitis: failure to demonstrate a clinical effect.
Topics: Chronic Disease; Clinical Trials as Topic; Female; Follow-Up Studies; Humans; Male; Pain; Spine; Spo | 1990 |
Sulphasalazine in psoriatic arthritis: a double-blind placebo-controlled study.
Topics: Arthritis; Clinical Trials as Topic; Double-Blind Method; Humans; Immunoglobulins; Joints; Pain; Pla | 1990 |
Meta-analysis of sulfasalazine in ankylosing spondylitis.
Topics: Double-Blind Method; Humans; Meta-Analysis as Topic; Outcome and Process Assessment, Health Care; Pa | 1990 |
A controlled trial comparing sulfasalazine, gold sodium thiomalate, and placebo in rheumatoid arthritis.
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Gold Sodium | 1988 |
12 other studies available for sulfasalazine and Ache
| Article | Year |
|---|---|
Jiaolong capsule protects SD rats against 2,4,6-trinitrobenzene sulfonic acid induced colitis.
Topics: Acetic Acid; Animals; Behavior, Animal; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Dinoprostone; | 2021 |
Limonene from Agastache mexicana essential oil produces antinociceptive effects, gastrointestinal protection and improves experimental ulcerative colitis.
Topics: Agastache; Analgesics; Animals; Colitis, Ulcerative; Disease Models, Animal; Dose-Response Relations | 2021 |
Inhibition of breast cancer-cell glutamate release with sulfasalazine limits cancer-induced bone pain.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Bone and Bones; Breast | 2014 |
Bilateral hip pain in a young man? It may be worth considering juvenile-onset ankylosing spondylitis (JAS).
Topics: Adolescent; Anti-Inflammatory Agents; Arthritis, Juvenile; Hip Joint; Humans; Male; Methylprednisolo | 2015 |
Sulfasalazine blocks the development of tactile allodynia in diabetic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; Chromatography, High P | 2008 |
Late onset spondyloarthropathy mimicking polymyalgia rheumatica.
Topics: Age of Onset; Anti-Inflammatory Agents; Biomarkers; Blood Sedimentation; C-Reactive Protein; Diagnos | 2012 |
Nine years of diarrhea and abdominal pain.
Topics: Aged; Crohn Disease; Diarrhea; Duodenal Diseases; Female; Humans; Joint Diseases; Pain; Prednisone; | 1983 |
Sapho syndrome with femoral hyperostosis. Two case-reports.
Topics: Adult; Antirheumatic Agents; Diphosphonates; Female; Femur; Humans; Hyperostosis; Magnetic Resonance | 1996 |
Seronegative spondyloarthropathy in familial Mediterranean fever.
Topics: Achilles Tendon; Adrenal Cortex Hormones; Adult; Ankle; Anti-Inflammatory Agents, Non-Steroidal; Ant | 1997 |
[Chronic recurrent multifocal osteomyelitis in children: report of 17 cases].
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Bone and Bones; Child; Child, Pr | 2001 |
Inflammatory bowel disease in the pregnant woman.
Topics: Abdomen; Adrenal Cortex Hormones; Adult; Animals; Breast Feeding; Colitis, Ulcerative; Crohn Disease | 1985 |
The drug therapy of ulcerative colitis and of Crohn's disease.
Topics: Adrenocorticotropic Hormone; Atropine; Azathioprine; Colitis, Ulcerative; Crohn Disease; Diarrhea; D | 1974 |