sulfasalazine has been researched along with Absence Seizure in 9 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aimed to reveal the anti-convulsant effects sulfasalazine and its mechanism in pentylenetetrazole (PTZ)-induced seizures in rats." | 8.02 | The effect of sulfasalazine in pentylenetetrazole-induced seizures in rats. ( Akyol, PY; Bora, ES; Erbaş, O; Karaali, R; Yurtsever, G, 2021) |
| "A severe systemic reaction to sulfasalazine developed in a 21-year old female with rheumatoid arthritis characterized by eosinophilia, granulomatous enteritis and myelotoxicity, cholestatic hepatitis, and seizures." | 7.71 | Is it Crohn's disease? A severe systemic granulomatous reaction to sulfasalazine in patient with rheumatoid arthritis. ( Fontana, RJ; Greenson, J; Haftel, HM; Quallich, LG, 2001) |
| "We describe the case of a 46-year-old woman with rheumatoid arthritis who developed a severe reaction to sulfasalazine, characterized by dysphasia, seizures, rash and the development of strongly positive pANCA (perinuclear antineutrophil cytoplasmic antibodies)." | 7.69 | Sulfasalazine induced seizures and dysphasia. ( Gordon, C; Heath, DA; Hill, ME; Situnayake, RD, 1994) |
| "We aimed to reveal the anti-convulsant effects sulfasalazine and its mechanism in pentylenetetrazole (PTZ)-induced seizures in rats." | 4.02 | The effect of sulfasalazine in pentylenetetrazole-induced seizures in rats. ( Akyol, PY; Bora, ES; Erbaş, O; Karaali, R; Yurtsever, G, 2021) |
| "A severe systemic reaction to sulfasalazine developed in a 21-year old female with rheumatoid arthritis characterized by eosinophilia, granulomatous enteritis and myelotoxicity, cholestatic hepatitis, and seizures." | 3.71 | Is it Crohn's disease? A severe systemic granulomatous reaction to sulfasalazine in patient with rheumatoid arthritis. ( Fontana, RJ; Greenson, J; Haftel, HM; Quallich, LG, 2001) |
| "We describe the case of a 46-year-old woman with rheumatoid arthritis who developed a severe reaction to sulfasalazine, characterized by dysphasia, seizures, rash and the development of strongly positive pANCA (perinuclear antineutrophil cytoplasmic antibodies)." | 3.69 | Sulfasalazine induced seizures and dysphasia. ( Gordon, C; Heath, DA; Hill, ME; Situnayake, RD, 1994) |
| "This was a case of central-variant posterior reversible encephalopathy syndrome due to sulfasalazine, and atypical imaging findings should be kept in mind for early diagnosis." | 1.42 | Central-Variant Posterior Reversible Encephalopathy due to Sulfasalazine: A Case Report. ( Demirtas, BS; Ocek, L; Ozcelik, MM; Oztekin, O; Sener, U; Zorlu, Y, 2015) |
| "Control of seizures in patients with gliomas is an essential component of clinical management; therefore, understanding the origin of seizures is vital." | 1.38 | Human glioma cells induce hyperexcitability in cortical networks. ( Buckingham, SC; Campbell, SL; Sontheimer, H, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Bora, ES | 1 |
| Karaali, R | 1 |
| Akyol, PY | 1 |
| Yurtsever, G | 1 |
| Erbaş, O | 1 |
| Alcoreza, O | 1 |
| Jagarlamudi, S | 1 |
| Savoia, A | 1 |
| Campbell, SL | 2 |
| Sontheimer, H | 2 |
| Blecic, S | 1 |
| Rynkowski, M | 1 |
| De Witte, O | 1 |
| Lefranc, F | 1 |
| Ocek, L | 1 |
| Sener, U | 1 |
| Demirtas, BS | 1 |
| Ozcelik, MM | 1 |
| Oztekin, O | 1 |
| Zorlu, Y | 1 |
| Buckingham, SC | 1 |
| Hill, ME | 1 |
| Gordon, C | 1 |
| Situnayake, RD | 1 |
| Heath, DA | 1 |
| Heath, KJ | 1 |
| Sampson, MJ | 1 |
| Ridley, SA | 1 |
| Sentürk, T | 1 |
| Aydintuğ, AO | 1 |
| Düzgün, N | 1 |
| Tokgöz, G | 1 |
| Quallich, LG | 1 |
| Greenson, J | 1 |
| Haftel, HM | 1 |
| Fontana, RJ | 1 |
1 review available for sulfasalazine and Absence Seizure
| Article | Year |
|---|---|
[Glutamate and malignant gliomas, from epilepsia to biological aggressiveness: therapeutic implications].
Topics: Benzodiazepines; Brain Neoplasms; Cell Death; Cell Movement; Cell Proliferation; Dizocilpine Maleate | 2013 |
8 other studies available for sulfasalazine and Absence Seizure
| Article | Year |
|---|---|
The effect of sulfasalazine in pentylenetetrazole-induced seizures in rats.
Topics: Animals; Male; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Rats, Wistar; Seizures; Sulfasalazine | 2021 |
Sulfasalazine decreases astrogliosis-mediated seizure burden.
Topics: Animals; Antiporters; Electroencephalography; Epilepsy; Gliosis; Glutamic Acid; Humans; Mice; Seizur | 2022 |
Central-Variant Posterior Reversible Encephalopathy due to Sulfasalazine: A Case Report.
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Brain; Female; Humans; Magnetic Resonance Imaging; Middl | 2015 |
Human glioma cells induce hyperexcitability in cortical networks.
Topics: Action Potentials; Animals; Brain; Brain Neoplasms; Disease Models, Animal; Electrophysiology; Femal | 2012 |
Sulfasalazine induced seizures and dysphasia.
Topics: Antibodies, Antineutrophil Cytoplasmic; Aphasia; Arthritis, Rheumatoid; Autoantibodies; Female; Huma | 1994 |
An unusual cause for collapse in a patient with arthritis.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Critical Care; Diagnosis, Differential; Female; H | 1996 |
Seizures and hepatotoxicity following sulphasalazine administration.
Topics: Adult; Antirheumatic Agents; Arthritis; Chemical and Drug Induced Liver Injury; Chronic Disease; Fem | 1997 |
Is it Crohn's disease? A severe systemic granulomatous reaction to sulfasalazine in patient with rheumatoid arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Crohn Di | 2001 |