sulfasalazine has been researched along with Abnormalities, Drug-Induced in 18 studies
Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We found no significant increased prevalence of selected congenital abnormalities in the children of women treated with sulfasalazine during pregnancy." | 7.71 | Population-based case control study of the safety of sulfasalazine use during pregnancy. ( Czeizel, AE; Nørgård, B; Olsen, J; Rockenbauer, M; Sørensen, HT, 2001) |
| "We found no significant increased prevalence of selected congenital abnormalities in the children of women treated with sulfasalazine during pregnancy." | 3.71 | Population-based case control study of the safety of sulfasalazine use during pregnancy. ( Czeizel, AE; Nørgård, B; Olsen, J; Rockenbauer, M; Sørensen, HT, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (44.44) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Hammad, I | 1 |
| Porter, TF | 1 |
| Brar, H | 1 |
| Einarson, A | 1 |
| Källén, B | 1 |
| Ostensen, M | 1 |
| Chambers, C | 1 |
| Koren, G | 1 |
| Tutuncu, ZN | 1 |
| Johnson, D | 1 |
| Jones, KL | 1 |
| Fahrländer, H | 2 |
| Craxi, A | 1 |
| Pagliarello, F | 1 |
| Littler, TR | 1 |
| Korelitz, BI | 1 |
| Newman, NM | 1 |
| Correy, JF | 1 |
| Winship, KA | 1 |
| Cahal, DA | 1 |
| Weber, JC | 1 |
| Griffin, JP | 1 |
| Koyama, N | 1 |
| Komori, S | 1 |
| Bessho, T | 1 |
| Koyama, K | 1 |
| Hiraumi, Y | 1 |
| Maeda, Y | 1 |
| Moody, GA | 1 |
| Probert, C | 1 |
| Jayanthi, V | 1 |
| Mayberry, JF | 1 |
| Amitai, Y | 1 |
| Leventhal, A | 1 |
| Nørgård, B | 1 |
| Czeizel, AE | 1 |
| Rockenbauer, M | 1 |
| Olsen, J | 1 |
| Sørensen, HT | 1 |
| Xiong, JM | 1 |
| Liang, B | 1 |
| Mo, YQ | 1 |
| Chen, ZH | 1 |
| Hoo, JJ | 1 |
| Hadro, TA | 1 |
| Von Behren, P | 1 |
4 reviews available for sulfasalazine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
An Update on Biologic Agents During Pregnancy.
Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humani | 2020 |
[Antirheumatic therapy and reproduction. The influence on fertility, pregnancy and breast feeding].
Topics: Abnormalities, Drug-Induced; Antirheumatic Agents; Breast Feeding; Cyclophosphamide; Drug Combinatio | 2006 |
Are new agents used to treat rheumatoid arthritis safe to take during pregnancy? Organization of Teratology Information Specialists (OTIS) study.
Topics: Abnormalities, Drug-Induced; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprin | 2007 |
Anti-rheumatic drugs.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Dapso | 1981 |
14 other studies available for sulfasalazine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Effects and treatment of inflammatory bowel disease during pregnancy.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Adult; Aminosalicylic Acids; Anti-Infective Ag | 2008 |
Maternal drug use and infant cleft lip/palate with special reference to corticoids.
Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Cleft Lip; Cl | 2003 |
[Salazosulfapyridine in pregnancy?].
Topics: Abnormalities, Drug-Induced; Colitis, Ulcerative; Female; Humans; Pregnancy; Sulfasalazine | 1980 |
Possible embryotoxicity of sulfasalazine.
Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Colitis, Ulcerative; Female; Humans; Hydroceph | 1980 |
Pregnancy and inflammatory bowel disease.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adrenal Cortex Hormones; Colitis, Ulcerative; Cr | 1982 |
Possible teratogenicity of sulphasalazine.
Topics: Abnormalities, Drug-Induced; Adult; Colitis; Diseases in Twins; Female; Heart Defects, Congenital; H | 1983 |
Maternal drug histories and central nervous system anomalies.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Adult; Anti-Inflammatory Agents; F | 1984 |
[Azulfidine/Salazopyrin therapy during pregnancy].
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Colitis, Ulcerative; Crohn Disease; Female; Humans; I | 1981 |
Holoprosencephaly in a fetus with maternal medication of sulfasalazine in early gestation. A case report.
Topics: Abnormalities, Drug-Induced; Adult; Anti-Inflammatory Agents; Crohn Disease; Fatal Outcome; Female; | 1996 |
The effects of chronic ill health and treatment with sulphasalazine on fertility amongst men and women with inflammatory bowel disease in Leicestershire.
Topics: Abnormalities, Drug-Induced; Adult; Chronic Disease; Female; Fertility; Humans; Infant, Newborn; Inf | 1997 |
Folic acid antagonists during pregnancy and risk of birth defects.
Topics: Abnormalities, Drug-Induced; Cleft Lip; Female; Folic Acid Antagonists; Heart Defects, Congenital; H | 2001 |
Population-based case control study of the safety of sulfasalazine use during pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Case-Control Studies; Female; Gastrointestinal Agents; Humans; I | 2001 |
[Teratologic studies of methyl 5-aminosalicylate and salicylazopyridine].
Topics: Abnormalities, Drug-Induced; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; | 1992 |
Possible teratogenicity of sulfasalazine.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Colitis, Ulcerative; Female; Humans; In | 1988 |