Page last updated: 2024-11-04

sulfasalazine and Abdominal Pain

sulfasalazine has been researched along with Abdominal Pain in 13 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Abdominal Pain: Sensation of discomfort, distress, or agony in the abdominal region.

Research Excerpts

ExcerptRelevanceReference
"Mesalamine suppositories have been used widely for the treatment of distal ulcerative colitis and considered to be safer than systemic administration for its limited systemic absorption."5.40Ulcerative colitis flair induced by mesalamine suppositories hypersensitivity. ( Ding, H; Hu, J; Hu, XY; Liu, XC; Mei, Q; Xu, JM, 2014)
"AP is an important complaint in young adults with JIA and is associated with fatigue, female gender, methotrexate and sulfasalazine use."4.12Abdominal pain in Finnish young adults with juvenile idiopathic arthritis. ( Aalto, K; Glerup, M; Kautiainen, H; Peltoniemi, S; Rebane, K; Tuomi, AK, 2022)
"Although oral mesalamine is the first-choice drug for treating mild-to-moderate ulcerative colitis (UC), some patients show symptoms of intolerance, including exacerbation of diarrhea and abdominal pain."4.02Multicenter survey on mesalamine intolerance in patients with ulcerative colitis. ( Fujiwara, A; Higashi, R; Hiraoka, S; Inokuchi, T; Kato, J; Matsueda, K; Miyaike, J; Moritou, Y; Okada, H; Suzuki, S; Takagi, S; Takahara, M; Toyokawa, T, 2021)
"5-ASA is used as first-line therapy for ulcerative colitis."3.01Significance of 5-Aminosalicylic Acid Intolerance in the Clinical Management of Ulcerative Colitis. ( Kanai, T; Kiyohara, H; Mikami, Y; Mizushima, I; Suzuki, S; Tsunoda, J, 2023)
"Ulcerative colitis is a chronic inflammatory disease of the colon where leukotrienes are suggested to play an important role for keeping inflammation active."2.68Effects of Boswellia serrata gum resin in patients with ulcerative colitis. ( Ammon, HP; Gupta, I; Lüdtke, R; Malhotra, P; Parihar, A; Safayhi, H; Singh, GB, 1997)
"Mesalamine suppositories have been used widely for the treatment of distal ulcerative colitis and considered to be safer than systemic administration for its limited systemic absorption."1.40Ulcerative colitis flair induced by mesalamine suppositories hypersensitivity. ( Ding, H; Hu, J; Hu, XY; Liu, XC; Mei, Q; Xu, JM, 2014)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (23.08)18.2507
2000's2 (15.38)29.6817
2010's4 (30.77)24.3611
2020's4 (30.77)2.80

Authors

AuthorsStudies
Rebane, K1
Tuomi, AK1
Kautiainen, H1
Peltoniemi, S1
Glerup, M1
Aalto, K1
Mikami, Y1
Tsunoda, J1
Suzuki, S2
Mizushima, I1
Kiyohara, H1
Kanai, T1
Hiraoka, S1
Fujiwara, A1
Toyokawa, T1
Higashi, R1
Moritou, Y1
Takagi, S1
Matsueda, K1
Miyaike, J1
Inokuchi, T1
Takahara, M1
Kato, J1
Okada, H1
Sinopoulou, V1
Gordon, M1
Dovey, TM1
Akobeng, AK1
Soga, K1
Itani, K1
John, KJ1
Sadiq, M1
Thomas, M1
Turaka, VP1
Ding, H1
Liu, XC1
Mei, Q1
Xu, JM1
Hu, XY1
Hu, J1
Vermeer, M1
Kuper, HH1
Bernelot Moens, HJ1
Hoekstra, M1
Posthumus, MD1
van Riel, PL1
van de Laar, MA1
Gupta, I1
Parihar, A1
Malhotra, P1
Singh, GB1
Lüdtke, R1
Safayhi, H1
Ammon, HP1
Yoshimura, K1
Hirata, I1
Maemura, K1
Sugi, K1
Tahara, T1
Iofel, E1
Chawla, A1
Daum, F1
Markowitz, J1
Butt, JH1
Simenon, G1
Van Gossum, A1
Adler, M1
Rickaert, F1
Appelboom, T1

Reviews

3 reviews available for sulfasalazine and Abdominal Pain

ArticleYear
Significance of 5-Aminosalicylic Acid Intolerance in the Clinical Management of Ulcerative Colitis.
    Digestion, 2023, Volume: 104, Issue:1

    Topics: Abdominal Pain; Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative;

2023
Interventions for the management of abdominal pain in ulcerative colitis.
    The Cochrane database of systematic reviews, 2021, 07-22, Volume: 7

    Topics: Abdominal Pain; Adult; Bias; Colitis, Ulcerative; Diet, Carbohydrate-Restricted; Gastrointestinal Ag

2021
Outpatient management of inflammatory bowel disease. Let's keep it as simple as possible.
    Postgraduate medicine, 1992, Nov-01, Volume: 92, Issue:6

    Topics: Abdominal Pain; Adrenal Cortex Hormones; Ambulatory Care; Aminosalicylic Acids; Anus Diseases; Diarr

1992

Trials

1 trial available for sulfasalazine and Abdominal Pain

ArticleYear
Effects of Boswellia serrata gum resin in patients with ulcerative colitis.
    European journal of medical research, 1997, Volume: 2, Issue:1

    Topics: Abdominal Pain; Adolescent; Adult; Biopsy; Blood Proteins; Body Weight; Calcium; Child; Colitis, Ulc

1997

Other Studies

9 other studies available for sulfasalazine and Abdominal Pain

ArticleYear
Abdominal pain in Finnish young adults with juvenile idiopathic arthritis.
    Scandinavian journal of gastroenterology, 2022, Volume: 57, Issue:10

    Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheuma

2022
Multicenter survey on mesalamine intolerance in patients with ulcerative colitis.
    Journal of gastroenterology and hepatology, 2021, Volume: 36, Issue:1

    Topics: Abdominal Pain; Administration, Oral; Adult; Colitis, Ulcerative; Diarrhea; Disease Progression; Fem

2021
Hyposensitization trial using salazosulfapyridine in a case of mesalamine intolerance.
    Clinical journal of gastroenterology, 2019, Volume: 12, Issue:6

    Topics: Abdominal Pain; Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative;

2019
Henoch-Schonlein purpura associated with HLA-B27 positive axial spondyloarthritis in a young man.
    BMJ case reports, 2019, May-24, Volume: 12, Issue:5

    Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; HLA-B27 Antige

2019
Ulcerative colitis flair induced by mesalamine suppositories hypersensitivity.
    World journal of gastroenterology, 2014, Apr-07, Volume: 20, Issue:13

    Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Colonoscopy; Di

2014
Adherence to a treat-to-target strategy in early rheumatoid arthritis: results of the DREAM remission induction cohort.
    Arthritis research & therapy, 2012, Nov-23, Volume: 14, Issue:6

    Topics: Abdominal Pain; Adalimumab; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized;

2012
Radiation enteritis: a rare complication of the transverse colon in uterine cancer.
    Internal medicine (Tokyo, Japan), 2000, Volume: 39, Issue:12

    Topics: Abdominal Pain; Anastomosis, Surgical; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative;

2000
Mesalamine intolerance mimics symptoms of active inflammatory bowel disease.
    Journal of pediatric gastroenterology and nutrition, 2002, Volume: 34, Issue:1

    Topics: Abdominal Pain; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Female; Humans; Infla

2002
Macroscopic and microscopic gut lesions in seronegative spondyloarthropathies.
    The Journal of rheumatology, 1990, Volume: 17, Issue:11

    Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents, Non-Steroidal; Colon; Colonoscopy; Female; Humans;

1990