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sulfasalazine and ACL Injuries

sulfasalazine has been researched along with ACL Injuries in 1 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Research Excerpts

ExcerptRelevanceReference
"Sulfasalazine (SSZ) is a system XC- inhibitor; SSZ was applied intra-articularly to study the function of system XC- in the development of OA in rats subjected to anterior cruciate ligament transection and medial meniscectomy (ACLT + MMx)."1.43Sulfasalazine attenuates ACL transection and medial menisectomy-induced cartilage destruction by inhibition of cystine/glutamate antiporter. ( Liu, CC; Tsai, RY; Tsai, WY; Wong, CS; Wu, JL, 2016)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tsai, WY1
Tsai, RY1
Liu, CC1
Wu, JL1
Wong, CS1

Other Studies

1 other study available for sulfasalazine and ACL Injuries

ArticleYear
Sulfasalazine attenuates ACL transection and medial menisectomy-induced cartilage destruction by inhibition of cystine/glutamate antiporter.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2016, Volume: 34, Issue:4

    Topics: Animals; Anterior Cruciate Ligament Injuries; Antiporters; Antirheumatic Agents; Cells, Cultured; Ch

2016