Page last updated: 2024-11-04

sulfasalazine and 2019 Novel Coronavirus Disease

sulfasalazine has been researched along with 2019 Novel Coronavirus Disease in 13 studies

Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.

Research Excerpts

ExcerptRelevanceReference
"Sulfasalazine was indicated in two cases."3.01Reactive arthritis occurring after COVID-19 infection: a narrative review. ( Abbes, M; Dhahri, R; Gharsallah, I; Louzir, B; Mehmli, T; Metoui, L; Slouma, M, 2023)
"There is paucity of data on extended dosing interval between two doses of AZD1222 (AstraZeneca) in patients with Autoimmune Rheumatic Diseases (AIRD)."1.72Effectiveness of delayed second dose of AZD1222 vaccine in patients with autoimmune rheumatic disease. ( Ahmed, S; Benny, J; Cherian, S; Mehta, P; Panthak, A; Paul, A; Shenoy, P, 2022)
"The majority of patients had Crohn's disease (CD) (60%) and most of them were in clinical remission."1.62COVID-19 in IBD: The experience of a single tertiary IBD center. ( Belluzzi, A; Calabrese, C; Calandrini, L; Decorato, A; Dussias, N; Filippone, E; Gionchetti, P; Laureti, S; Melotti, L; Peruzzi, G; Poggioli, G; Privitera, H; Rizzello, F; Rottoli, M; Salice, M; Scaioli, E; Siniscalchi, A, 2021)
"The impact of Coronavirus disease 2019 (COVID-19) on patients with inflammatory bowel disease (IBD) is unknown."1.56Corticosteroids, But Not TNF Antagonists, Are Associated With Adverse COVID-19 Outcomes in Patients With Inflammatory Bowel Diseases: Results From an International Registry. ( Brenner, EJ; Colombel, JF; Gearry, RB; Kaplan, GG; Kappelman, MD; Kissous-Hunt, M; Lewis, JD; Ng, SC; Rahier, JF; Reinisch, W; Ruemmele, FM; Steinwurz, F; Underwood, FE; Ungaro, RC; Zhang, X, 2020)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's13 (100.00)2.80

Authors

AuthorsStudies
Ungaro, RC3
Brenner, EJ3
Agrawal, M1
Zhang, X3
Kappelman, MD3
Colombel, JF3
Slouma, M1
Abbes, M1
Mehmli, T1
Dhahri, R1
Metoui, L1
Gharsallah, I1
Louzir, B1
Mehta, P1
Paul, A1
Ahmed, S1
Cherian, S1
Panthak, A1
Benny, J1
Shenoy, P1
G S Saad, C1
S R Silva, M1
Sampaio-Barros, PD1
C B Moraes, J1
G Schainberg, C1
Gonçalves, CR1
Shimabuco, AY1
Aikawa, NE1
F N Yuki, E1
G Pasoto, S1
V K Kupa, L1
K Aoyama, R1
S R Araujo, C1
Silva, CA1
Medeiros-Ribeiro, AC1
Bonfa, E1
Armağan, B1
Atalar, E1
Güven, SC1
Özdemir, B1
Konak, HE1
Akyüz Dağlı, P1
Erden, A1
Gök, K1
Maraş, Y1
Doğan, İ1
Küçükşahin, O1
Erten, Ş1
Omma, A1
Barrett, R2
Lin, SX1
Culliford, D1
Fraser, S1
Edwards, CJ1
Gearry, RB1
Kaplan, GG1
Kissous-Hunt, M1
Lewis, JD1
Ng, SC1
Rahier, JF1
Reinisch, W1
Ruemmele, FM2
Steinwurz, F1
Underwood, FE1
Pers, YM1
Padern, G1
Pigneur, B1
Focht, G1
Turner, D1
Balconi, SN1
Lopes, NT1
Luzzatto, L1
Bonamigo, RR1
Rizzello, F1
Calabrese, C1
Salice, M1
Calandrini, L1
Privitera, H1
Melotti, L1
Peruzzi, G1
Dussias, N1
Belluzzi, A1
Scaioli, E1
Decorato, A1
Siniscalchi, A1
Filippone, E1
Laureti, S1
Rottoli, M1
Poggioli, G1
Gionchetti, P1
Han, N1
Hwang, W1
Tzelepis, K1
Schmerer, P1
Yankova, E1
MacMahon, M1
Lei, W1
M Katritsis, N1
Liu, A1
Felgenhauer, U1
Schuldt, A1
Harris, R1
Chapman, K1
McCaughan, F1
Weber, F1
Kouzarides, T1
Roy, S1
Sheikh, SZ1
Furey, TS1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Immunogenicity and Safety of the CoronaVac Vacccine in Patients With Autoimmune Rheumatic Diseases and People Living With HIV/AIDS[NCT04754698]Phase 42,067 participants (Anticipated)Interventional2021-02-09Active, not recruiting
Monitoring Serologic Response to SARS-COV-2 / Coronavirus Disease 2019 (COVID-19) in Children, Adolescents, and Young Adults Receiving Biologic Therapies (RECONN)[NCT04838834]472 participants (Actual)Observational2020-05-15Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for sulfasalazine and 2019 Novel Coronavirus Disease

ArticleYear
Reactive arthritis occurring after COVID-19 infection: a narrative review.
    Infection, 2023, Volume: 51, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Reactive; COVID-19; Female; Humans; Male;

2023

Trials

1 trial available for sulfasalazine and 2019 Novel Coronavirus Disease

ArticleYear
Interaction of TNFi and conventional synthetic DMARD in SARS-CoV-2 vaccine response in axial spondyloarthritis and psoriatic arthritis.
    Joint bone spine, 2023, Volume: 90, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Psoriatic; Axial Spondyloarthritis; COVID-19; COVID-19 Vaccines; Fe

2023

Other Studies

11 other studies available for sulfasalazine and 2019 Novel Coronavirus Disease

ArticleYear
Impact of Medications on COVID-19 Outcomes in Inflammatory Bowel Disease: Analysis of More Than 6000 Patients From an International Registry.
    Gastroenterology, 2022, Volume: 162, Issue:1

    Topics: Adrenal Cortex Hormones; COVID-19; Humans; Inflammatory Bowel Diseases; Mesalamine; Registries; SARS

2022
Effectiveness of delayed second dose of AZD1222 vaccine in patients with autoimmune rheumatic disease.
    Clinical rheumatology, 2022, Volume: 41, Issue:11

    Topics: Autoimmune Diseases; ChAdOx1 nCoV-19; COVID-19; COVID-19 Vaccines; Humans; Methotrexate; Mycophenoli

2022
Effects of sulfasalazine in axial spondyloarthritis on COVID-19 outcomes: real-life data from a single center.
    Immunopharmacology and immunotoxicology, 2023, Volume: 45, Issue:4

    Topics: Axial Spondyloarthritis; Biological Products; COVID-19; Female; Humans; Male; Middle Aged; Retrospec

2023
Impact of the COVID-19 pandemic on prescription refills for immune-mediated inflammatory disorders: a time series analysis (January 2019 to January 2021) using the English Prescribing Dataset.
    BMJ open, 2022, 12-23, Volume: 12, Issue:12

    Topics: Azathioprine; Communicable Disease Control; COVID-19; Drug Prescriptions; Humans; Hydroxychloroquine

2022
Corticosteroids, But Not TNF Antagonists, Are Associated With Adverse COVID-19 Outcomes in Patients With Inflammatory Bowel Diseases: Results From an International Registry.
    Gastroenterology, 2020, Volume: 159, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Aged; Betacoronavirus; Comorbidity; Coronavirus Infections; COVID-19

2020
Revisiting the cardiovascular risk of hydroxychloroquine in RA.
    Nature reviews. Rheumatology, 2020, Volume: 16, Issue:12

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antimalarials; Arthritis, Rheumatoid; Azithromycin; Ca

2020
Benign Evolution of SARS-Cov2 Infections in Children With Inflammatory Bowel Disease: Results From Two International Databases.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2021, Volume: 19, Issue:2

    Topics: Adolescent; Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Child; Colitis, Ulcerative; Co

2021
Detection of SARS-CoV-2 in a case of DRESS by sulfasalazine: could there be a relationship with clinical importance?
    International journal of dermatology, 2021, Volume: 60, Issue:1

    Topics: COVID-19; Drug Hypersensitivity Syndrome; Female; Humans; SARS-CoV-2; Sulfasalazine; Young Adult

2021
COVID-19 in IBD: The experience of a single tertiary IBD center.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2021, Volume: 53, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Biological Products;

2021
Identification of SARS-CoV-2-induced pathways reveals drug repurposing strategies.
    Science advances, 2021, Volume: 7, Issue:27

    Topics: Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Drug Repositioning; Humans; Neural Networks, Co

2021
A machine learning approach identifies 5-ASA and ulcerative colitis as being linked with higher COVID-19 mortality in patients with IBD.
    Scientific reports, 2021, 08-13, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, P

2021