Page last updated: 2024-11-04

sulfapyridine and Pregnancy

sulfapyridine has been researched along with Pregnancy in 15 studies

Sulfapyridine: Antibacterial, potentially toxic, used to treat certain skin diseases.
sulfapyridine : A sulfonamide consisting of pyridine with a 4-aminobenzenesulfonamido group at the 2-position.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Sulfasalazine has been identified as a candidate molecule to be investigated as an intervention to treat preterm pre-eclampsia during pregnancy."4.31An LC-MS/MS method for the simultaneous quantitation of sulfasalazine and sulfapyridine in human placenta. ( Brownfoot, F; Cluver, C; Decloedt, E; Kellermann, T; Louw, V, 2023)
"In eleven pregnant patients with ulcerative colitis or Crohn's disease who were treated with sulphasalazine (SASP) the serum concentrations of SASP and sulphapyridine (SP) were measured at delivery."1.26Placental transfer of sulphasalazine and sulphapyridine and some of its metabolites. ( Esbjörner, E; Into-Malmberg, MB; Järnerot, G, 1981)
"Twelve pregnant patients with ulcerative colitis or Crohn's disease who were being treated with sulphasalazine (SASP) were studied together with their newborn, full-term babies."1.26Albumin reserve for binding of bilirubin in maternal and cord serum under treatment with sulphasalazine. ( Andersen, S; Brodersen, R; Esbjörner, E; Järnerot, G; Sandström, B, 1981)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199012 (80.00)18.7374
1990's1 (6.67)18.2507
2000's0 (0.00)29.6817
2010's1 (6.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Louw, V1
Brownfoot, F1
Cluver, C1
Decloedt, E1
Kellermann, T1
Wang, B1
Parobchak, N1
Martin, A1
Rosen, M1
Yu, LJ1
Nguyen, M1
Gololobova, K1
Rosen, T1
Järnerot, G5
Into-Malmberg, MB2
Esbjörner, E3
Andersen, S1
Sandström, B1
Brodersen, R1
Berenguer, J1
O'Moráin, C1
Smethurst, P1
Doré, CJ1
Levi, AJ1
Khan, AK1
Truelove, SC1
Goldman, P1
Peppercorn, MA1
Winkler, R1
Pholpramool, C1
Ruchirawat, S1
Verawatnapakul, V1
Paovalo, C1
Lewin, LM1
Banatwala, N1
Wranne, L1
Abba, Z1
Harms, M1
Didierjean, L1
Saurat, JH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Sulfasalazine on CRH Levels in Pregnant Women With a History of Pre-Term Birth: A Randomized Controlled Trial[NCT05703425]Phase 250 participants (Anticipated)Interventional2023-03-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for sulfapyridine and Pregnancy

ArticleYear
Drug therapy: Sulfasalazine.
    The New England journal of medicine, 1975, Jul-03, Volume: 293, Issue:1

    Topics: Animals; Bacteria; Binding, Competitive; Biological Transport; Chemical Phenomena; Chemistry; Coliti

1975
Salazopyrin and its newer analogues in the treatment of inflammatory bowel disease.
    JPMA. The Journal of the Pakistan Medical Association, 1985, Volume: 35, Issue:3

    Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Double-Blind Method; Drug Combinations; Dr

1985

Other Studies

13 other studies available for sulfapyridine and Pregnancy

ArticleYear
An LC-MS/MS method for the simultaneous quantitation of sulfasalazine and sulfapyridine in human placenta.
    Journal of pharmaceutical and biomedical analysis, 2023, Oct-25, Volume: 235

    Topics: Chromatography, Liquid; Female; Humans; Infant, Newborn; Methanol; Placenta; Pre-Eclampsia; Pregnanc

2023
Screening a small molecule library to identify inhibitors of NF-κB inducing kinase and pro-labor genes in human placenta.
    Scientific reports, 2018, 01-26, Volume: 8, Issue:1

    Topics: Cells, Cultured; Corticotropin-Releasing Hormone; Cyclooxygenase 2; Drug Evaluation, Preclinical; Fe

2018
Placental transfer of sulphasalazine and sulphapyridine and some of its metabolites.
    Scandinavian journal of gastroenterology, 1981, Volume: 16, Issue:5

    Topics: Colitis; Colitis, Ulcerative; Crohn Disease; Female; Humans; Infant, Newborn; Maternal-Fetal Exchang

1981
Albumin reserve for binding of bilirubin in maternal and cord serum under treatment with sulphasalazine.
    Scandinavian journal of gastroenterology, 1981, Volume: 16, Issue:8

    Topics: Adult; Albumins; Bilirubin; Colitis, Ulcerative; Crohn Disease; Female; Fetal Blood; Humans; Infant,

1981
[Crohn's disease. Has there been progress in its treatment?].
    Medicina clinica, 1984, Jun-09, Volume: 83, Issue:2

    Topics: Crohn Disease; Drug Combinations; Female; Glucocorticoids; Glucosamine; Humans; Intestinal Obstructi

1984
Reversible male infertility due to sulphasalazine: studies in man and rat.
    Gut, 1984, Volume: 25, Issue:10

    Topics: Adult; Aminosalicylic Acids; Animals; Colitis, Ulcerative; Crohn Disease; Dose-Response Relationship

1984
[Appearance of sulfasalazine and sulfapyridine in breast milk and in the placental barrier as well as the effect of both substances on bilirubin binding to albumin].
    Zeitschrift fur Gastroenterologie. Verhandlungsband, 1981, Volume: 19

    Topics: Bilirubin; Colitis; Female; Fetal Blood; Humans; Infant, Newborn; Maternal-Fetal Exchange; Milk, Hum

1981
Placental and mammary transfer of sulphasalazine.
    British medical journal, 1979, Dec-15, Volume: 2, Issue:6204

    Topics: Colitis, Ulcerative; Female; Humans; Maternal-Fetal Exchange; Milk, Human; Pregnancy; Pregnancy Comp

1979
Sulphasalazine treatment during breast feeding.
    Scandinavian journal of gastroenterology, 1979, Volume: 14, Issue:7

    Topics: Colitis, Ulcerative; Crohn Disease; Female; Humans; Lactation; Milk, Human; Pregnancy; Sulfapyridine

1979
[Ulcerative colitis and pregnancy. Surgical treatment of acute complications (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1976, Jun-18, Volume: 101, Issue:25

    Topics: Adult; Age Factors; Colectomy; Colitis, Ulcerative; Colostomy; Female; Gastrointestinal Hemorrhage;

1976
Structural requirements of some sulphonamides that possess an antifertility activity in male rats.
    Journal of reproduction and fertility, 1991, Volume: 92, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Female; Infertility, Male; Male; Pregnancy; Rats; Rats, I

1991
Sulphasalazine and sulphapyridine serum levels in children to mothers treated with sulphasalazine during pregnancy and lactation.
    Acta paediatrica Scandinavica, 1987, Volume: 76, Issue:1

    Topics: Colitis, Ulcerative; Crohn Disease; Female; Humans; Infant, Newborn; Lactation; Maternal-Fetal Excha

1987
[Bullous pemphigoid in a 3-month-old child].
    Annales de dermatologie et de venereologie, 1988, Volume: 115, Issue:11

    Topics: Female; Humans; Immunoglobulin G; Infant; Male; Pemphigoid Gestationis; Pemphigoid, Bullous; Pregnan

1988