sulfapyridine has been researched along with Crohn Disease in 41 studies
Sulfapyridine: Antibacterial, potentially toxic, used to treat certain skin diseases.
sulfapyridine : A sulfonamide consisting of pyridine with a 4-aminobenzenesulfonamido group at the 2-position.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "paratuberculosis; isolates from Crohn's disease patients tended to be more susceptible than were bovine-origin isolates." | 1.35 | Thiopurine drugs azathioprine and 6-mercaptopurine inhibit Mycobacterium paratuberculosis growth in vitro. ( Collins, MT; Shin, SJ, 2008) |
| "In treatment of Crohn's disease, sulfasalazine has been shown to be effective when disease involves the colon or the colon and small intestine." | 1.27 | Pharmacotherapy of inflammatory bowel disease. Part 1. Sulfasalazine. ( Das, KM, 1983) |
| "In eleven pregnant patients with ulcerative colitis or Crohn's disease who were treated with sulphasalazine (SASP) the serum concentrations of SASP and sulphapyridine (SP) were measured at delivery." | 1.26 | Placental transfer of sulphasalazine and sulphapyridine and some of its metabolites. ( Esbjörner, E; Into-Malmberg, MB; Järnerot, G, 1981) |
| "Twelve pregnant patients with ulcerative colitis or Crohn's disease who were being treated with sulphasalazine (SASP) were studied together with their newborn, full-term babies." | 1.26 | Albumin reserve for binding of bilirubin in maternal and cord serum under treatment with sulphasalazine. ( Andersen, S; Brodersen, R; Esbjörner, E; Järnerot, G; Sandström, B, 1981) |
| "Seventeen patients with ulcerative colitis and three patients with Crohn's disease exhibited different side effects during sulfasalazine therapy." | 1.26 | Desensitization of patients with inflammatory bowel disease to sulfasalazine. ( Das, KM; Taffet, SL, 1982) |
| "In children three forms of Crohn's disease requiring operation have been identified." | 1.26 | Inflammatory bowel disease in childhood. ( Fonkalsrud, EW, 1981) |
| "The remission period of patients with ulcerative colitis was extended by long term treatment with 2-3 g sulphasalazine daily." | 1.26 | [Long-term therapy in ulcerative colitis and Crohn's disease]. ( Malchow, H, 1979) |
| "60 to 90% of patients with Crohn's disease have to undergo surgery due to complications; one half of these patients do suffer a relapse." | 1.26 | [Crohn's disease--Indication for surgery (author's transl)]. ( Herfarth, CH, 1978) |
| "Curative therapy of regional enteritis does not exist." | 1.26 | [Surgical and medical treatment of Crohn's disease (author's transl)]. ( Brünner, H; Eckhardt, R; Ewe, K; Krieg, H, 1977) |
| " A single study of serum can determine acetylator phenotype in patients on sulfasalazine therapy without using any other drug for this purpose and may help ascertain dosage and assess side effects." | 1.25 | Acetylation polymorphism of sulfapyridine in patients with ulcerative colitis and Crohn's disease. ( Das, KM; Eastwood, MA, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (85.37) | 18.7374 |
| 1990's | 3 (7.32) | 18.2507 |
| 2000's | 3 (7.32) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shin, SJ | 1 |
| Collins, MT | 1 |
| Hanauer, SB | 1 |
| Doering, J | 1 |
| Begue, B | 1 |
| Lentze, MJ | 1 |
| Rieux-Laucat, F | 1 |
| Goulet, O | 1 |
| Schmitz, J | 1 |
| Cerf-Bensussan, N | 1 |
| Ruemmele, FM | 1 |
| Day, JM | 1 |
| Houston, JB | 2 |
| Klotz, U | 1 |
| Maier, K | 1 |
| Fischer, C | 1 |
| Heinkel, K | 1 |
| Sharp, ME | 1 |
| Wallace, SM | 1 |
| Hindmarsh, KW | 1 |
| Brown, MA | 1 |
| Holdstock, G | 2 |
| Chastenay, BF | 2 |
| Krawitt, EL | 2 |
| Järnerot, G | 4 |
| Into-Malmberg, MB | 2 |
| Esbjörner, E | 3 |
| Andersen, S | 1 |
| Sandström, B | 1 |
| Brodersen, R | 1 |
| Eitner, K | 2 |
| Hippius, M | 2 |
| Reinicke, C | 2 |
| van Hees, PA | 2 |
| van Tongeren, JH | 2 |
| Taffet, SL | 1 |
| Das, KM | 3 |
| Berenguer, J | 1 |
| O'Moráin, C | 1 |
| Smethurst, P | 1 |
| Doré, CJ | 1 |
| Levi, AJ | 1 |
| Fonkalsrud, EW | 1 |
| Goebell, H | 1 |
| Goldstein, PD | 1 |
| Alpers, DH | 1 |
| Keating, JP | 1 |
| Dölle, W | 1 |
| Herfarth, C | 1 |
| Eastwood, MA | 1 |
| Malchow, H | 1 |
| Herfarth, CH | 1 |
| Binder, V | 1 |
| Deltz, E | 1 |
| Hantschmann, N | 1 |
| Krieg, H | 1 |
| Brünner, H | 1 |
| Ewe, K | 1 |
| Eckhardt, R | 1 |
| Base, W | 1 |
| Ferenci, P | 1 |
| Pesendorfer, FX | 1 |
| Aigner, O | 1 |
| Wewalka, F | 1 |
| Mahida, YR | 1 |
| Lamming, CE | 1 |
| Gallagher, A | 1 |
| Hawthorne, AB | 1 |
| Hawkey, CJ | 1 |
| Astbury, C | 1 |
| Taggart, AJ | 1 |
| Juby, L | 1 |
| Zebouni, L | 1 |
| Bird, HA | 1 |
| Donowitz, M | 1 |
| van Hogezand, RA | 1 |
| Zwanenburg, B | 1 |
| van Rossum, JM | 1 |
| Shaffer, JL | 1 |
| Banatwala, N | 1 |
| MacDermott, RP | 1 |
| Kane, MG | 1 |
| Steele, LL | 1 |
| Stenson, WF | 1 |
| Wranne, L | 1 |
| Okada, M | 1 |
| Yao, T | 1 |
| Turunen, U | 1 |
3 reviews available for sulfapyridine and Crohn Disease
| Article | Year |
|---|---|
[Crohn disease. How can short bowel syndrome be prevented?].
Topics: Combined Modality Therapy; Crohn Disease; Glucocorticoids; Humans; Postoperative Complications; Prog | 1993 |
Salazopyrin and its newer analogues in the treatment of inflammatory bowel disease.
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Double-Blind Method; Drug Combinations; Dr | 1985 |
[Management of refractory and fulminating colitis].
Topics: Aminosalicylic Acids; Colitis; Crohn Disease; Glucocorticoids; Humans; Mesalamine; Severity of Illne | 1987 |
3 trials available for sulfapyridine and Crohn Disease
| Article | Year |
|---|---|
Therapeutic efficacy of sulfasalazine and its metabolites in patients with ulcerative colitis and Crohn's disease.
Topics: Adult; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Humans; M | 1980 |
[Crohn study (summary of session 3)].
Topics: Clinical Trials as Topic; Crohn Disease; Humans; Methylprednisolone; Placebos; Sulfapyridine | 1976 |
[Indications for surgical and conservative therapy of Crohn's disease].
Topics: Acute Disease; Azathioprine; Chronic Disease; Clinical Trials as Topic; Crohn Disease; Humans; Intes | 1977 |
35 other studies available for sulfapyridine and Crohn Disease
| Article | Year |
|---|---|
Thiopurine drugs azathioprine and 6-mercaptopurine inhibit Mycobacterium paratuberculosis growth in vitro.
Topics: Animals; Azathioprine; Bacteriological Techniques; Cattle; Cattle Diseases; Colony Count, Microbial; | 2008 |
Mea culpa.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Crohn Disease; | 2008 |
Induction of T lymphocyte apoptosis by sulphasalazine in patients with Crohn's disease.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cells, Cultured; Child; Child | 2004 |
Saliva: plasma concentration relationships for sulphapyridine following sulphasalazine administration to normal volunteers and patients with inflammatory bowel disease.
Topics: Colitis, Ulcerative; Crohn Disease; Half-Life; Humans; Intestinal Absorption; Kinetics; Male; Phenot | 1980 |
Acetylator phenotype and serum levels of sulfapyridine in patients with inflammatory bowel disease.
Topics: Acetylation; Adolescent; Adult; Aged; Anti-Infective Agents; Colitis; Colitis, Ulcerative; Crohn Dis | 1981 |
Increased suppressor cell activity in inflammatory bowel disease.
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Humans; Hydrocortisone; In Vitro Technique | 1981 |
Placental transfer of sulphasalazine and sulphapyridine and some of its metabolites.
Topics: Colitis; Colitis, Ulcerative; Crohn Disease; Female; Humans; Infant, Newborn; Maternal-Fetal Exchang | 1981 |
Albumin reserve for binding of bilirubin in maternal and cord serum under treatment with sulphasalazine.
Topics: Adult; Albumins; Bilirubin; Colitis, Ulcerative; Crohn Disease; Female; Fetal Blood; Humans; Infant, | 1981 |
[Estimations of the serum levels of sulfapyridine on patients treated with sulfasalazin (author's transl)].
Topics: Adult; Colitis, Ulcerative; Crohn Disease; Female; Humans; Male; Sulfanilamides; Sulfapyridine; Sulf | 1982 |
Functional suppressor T cell activity in Crohn's disease and the effects of sulphasalazine.
Topics: Aminosalicylic Acids; Concanavalin A; Crohn Disease; Humans; Lymphocyte Activation; Mesalamine; Sulf | 1982 |
Compliance to therapy in patients on a maintenance dose of sulfasalazine.
Topics: Colitis, Ulcerative; Crohn Disease; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Pat | 1982 |
Desensitization of patients with inflammatory bowel disease to sulfasalazine.
Topics: Colitis, Ulcerative; Crohn Disease; Desensitization, Immunologic; Dose-Response Relationship, Drug; | 1982 |
Pharmacotherapy of inflammatory bowel disease. Part 1. Sulfasalazine.
Topics: Aminosalicylic Acids; Bacteria; Colitis, Ulcerative; Colon; Crohn Disease; Humans; Kinetics; Mesalam | 1983 |
[Crohn's disease. Has there been progress in its treatment?].
Topics: Crohn Disease; Drug Combinations; Female; Glucocorticoids; Glucosamine; Humans; Intestinal Obstructi | 1984 |
Reversible male infertility due to sulphasalazine: studies in man and rat.
Topics: Adult; Aminosalicylic Acids; Animals; Colitis, Ulcerative; Crohn Disease; Dose-Response Relationship | 1984 |
[Determination of sulfapyridine levels in serum--a possibility for the control of dose related therapy with sulfasalazine].
Topics: Adult; Colectomy; Colitis, Ulcerative; Crohn Disease; Dose-Response Relationship, Drug; Female; Huma | 1984 |
Inflammatory bowel disease in childhood.
Topics: Cecal Diseases; Child; Colectomy; Colitis, Ulcerative; Colostomy; Crohn Disease; Female; Humans; Ile | 1981 |
Crohn's disease of the colon.
Topics: Adrenal Cortex Hormones; Adult; Aminosalicylic Acids; Azathioprine; Colectomy; Colitis, Ulcerative; | 1979 |
Sulfapyridine metabolites in children with inflammatory bowel disease receiving sulfasalazine.
Topics: Acetylation; Adolescent; Child; Child, Preschool; Colitis, Ulcerative; Crohn Disease; Female; Humans | 1979 |
Sulphasalazine treatment during breast feeding.
Topics: Colitis, Ulcerative; Crohn Disease; Female; Humans; Lactation; Milk, Human; Pregnancy; Sulfapyridine | 1979 |
Acetylation polymorphism of sulfapyridine in patients with ulcerative colitis and Crohn's disease.
Topics: Acetylation; Adolescent; Adult; Aged; Colitis, Ulcerative; Crohn Disease; Female; Humans; Kinetics; | 1975 |
[Long-term therapy in ulcerative colitis and Crohn's disease].
Topics: Aminosalicylic Acids; Azathioprine; Colitis, Ulcerative; Crohn Disease; Humans; Metronidazole; Patie | 1979 |
[Crohn's disease--Indication for surgery (author's transl)].
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Crohn Disease; Female; Humans; Infant; Inte | 1978 |
[Chronic inflammatory intestinal diseases in childhood].
Topics: Child; Chronic Disease; Colitis, Ulcerative; Crohn Disease; Glucocorticoids; Humans; Sulfapyridine | 1978 |
[Results of surgical treatment of Crohn's enterocolitis granulomatosa (author's transl)].
Topics: Adolescent; Adult; Azathioprine; Cecum; Colon, Sigmoid; Crohn Disease; Follow-Up Studies; Humans; Il | 1976 |
[Surgical and medical treatment of Crohn's disease (author's transl)].
Topics: Acute Disease; Azathioprine; Chronic Disease; Crohn Disease; Drug Therapy, Combination; Female; Huma | 1977 |
[Nutritional problems in diseases of the small and large intestine].
Topics: Adolescent; Adult; Aged; Amino Acids; Body Weight; Colitis, Ulcerative; Crohn Disease; Female; Fissu | 1976 |
5-Aminosalicylic acid is a potent inhibitor of interleukin 1 beta production in organ culture of colonic biopsy specimens from patients with inflammatory bowel disease.
Topics: Adult; Aged; Aged, 80 and over; Aminosalicylic Acids; Colitis, Ulcerative; Colon; Crohn Disease; Dex | 1991 |
Comparison of the single dose pharmacokinetics of sulphasalazine in rheumatoid arthritis and inflammatory bowel disease.
Topics: Adult; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Female; Humans; Male; Middle Aged; | 1990 |
Arachidonic acid metabolites and their role in inflammatory bowel disease. An update requiring addition of a pathway.
Topics: Aminosalicylic Acids; Arachidonic Acid; Arachidonic Acids; Biological Transport; Bradykinin; Colitis | 1985 |
Disposition of disodium azodisalicylate in healthy subjects. A possible new drug for inflammatory bowel disease.
Topics: Administration, Oral; Aminosalicylic Acids; Crohn Disease; Half-Life; Humans; Kinetics; Mesalamine; | 1985 |
The effect of rifampicin on sulphapyridine plasma concentrations following sulphasalazine administration.
Topics: Adult; Crohn Disease; Drug Interactions; Ethambutol; Female; Humans; Male; Middle Aged; Rifampin; Su | 1985 |
Inhibition of cytotoxicity by sulfasalazine. I. Sulfasalazine inhibits spontaneous cell-mediated cytotoxicity by peripheral blood and intestinal mononuclear cells from control and inflammatory bowel disease patients.
Topics: Catechols; Colitis, Ulcerative; Crohn Disease; Cytotoxicity, Immunologic; Humans; Hydrocortisone; In | 1986 |
Sulphasalazine and sulphapyridine serum levels in children to mothers treated with sulphasalazine during pregnancy and lactation.
Topics: Colitis, Ulcerative; Crohn Disease; Female; Humans; Infant, Newborn; Lactation; Maternal-Fetal Excha | 1987 |
[Inflammatory bowel disease; internal therapy].
Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Drug Combinations | 1988 |