sulfaphenazole has been researched along with Reperfusion Injury in 3 studies
Sulfaphenazole: A sulfonilamide anti-infective agent.
sulfaphenazole : A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to establish the cardioprotective effect of sulfaphenazole (SPZ), a selective inhibitor of cytochrome P450 2C9 enzyme, in an in vivo rat model of acute myocardial infarction (MI)." | 7.75 | Sulfaphenazole protects heart against ischemia-reperfusion injury and cardiac dysfunction by overexpression of iNOS, leading to enhancement of nitric oxide bioavailability and tissue oxygenation. ( Hamlin, RL; Khan, M; Kotha, SR; Kuppusamy, P; Kutala, VK; Mohan, IK; Parinandi, NL, 2009) |
| "The objective of this study was to establish the cardioprotective effect of sulfaphenazole (SPZ), a selective inhibitor of cytochrome P450 2C9 enzyme, in an in vivo rat model of acute myocardial infarction (MI)." | 3.75 | Sulfaphenazole protects heart against ischemia-reperfusion injury and cardiac dysfunction by overexpression of iNOS, leading to enhancement of nitric oxide bioavailability and tissue oxygenation. ( Hamlin, RL; Khan, M; Kotha, SR; Kuppusamy, P; Kutala, VK; Mohan, IK; Parinandi, NL, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Turner, CT | 1 |
| Pawluk, M | 1 |
| Bolsoni, J | 1 |
| Zeglinski, MR | 1 |
| Shen, Y | 1 |
| Zhao, H | 1 |
| Ponomarev, T | 1 |
| Richardson, KC | 1 |
| West, CR | 1 |
| Papp, A | 1 |
| Granville, DJ | 1 |
| Khan, M | 1 |
| Mohan, IK | 1 |
| Kutala, VK | 1 |
| Kotha, SR | 1 |
| Parinandi, NL | 1 |
| Hamlin, RL | 1 |
| Kuppusamy, P | 1 |
| Ishihara, Y | 1 |
| Shimamoto, N | 1 |
3 other studies available for sulfaphenazole and Reperfusion Injury
| Article | Year |
|---|---|
Sulfaphenazole reduces thermal and pressure injury severity through rapid restoration of tissue perfusion.
Topics: Animals; Ischemia; Mice; Perfusion; Pressure Ulcer; Reactive Oxygen Species; Reperfusion Injury; Sul | 2022 |
Sulfaphenazole protects heart against ischemia-reperfusion injury and cardiac dysfunction by overexpression of iNOS, leading to enhancement of nitric oxide bioavailability and tissue oxygenation.
Topics: Animals; Biological Availability; Blood Pressure; Blotting, Western; Cardiotonic Agents; Disease Mod | 2009 |
Sulfaphenazole attenuates myocardial cell apoptosis accompanied with cardiac ischemia-reperfusion by suppressing the expression of BimEL and Noxa.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Caspase 3; Caspase 7; Cyto | 2012 |