sulfaphenazole has been researched along with Myocardial Ischemia in 1 studies
Sulfaphenazole: A sulfonilamide anti-infective agent.
sulfaphenazole : A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloramphenicol is an inhibitor of mitochondrial protein synthesis and is also an inhibitor of a subset of cytochrome P450 monooxygenases (CYPs)." | 1.32 | Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors. ( Gottlieb, RA; Granville, DJ; Gustafsson, AB; Huang, C; Sayen, MR; Takeuchi, C; Tashakkor, B; Wentworth, P; Yeager, M, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Granville, DJ | 1 |
| Tashakkor, B | 1 |
| Takeuchi, C | 1 |
| Gustafsson, AB | 1 |
| Huang, C | 1 |
| Sayen, MR | 1 |
| Wentworth, P | 1 |
| Yeager, M | 1 |
| Gottlieb, RA | 1 |
1 other study available for sulfaphenazole and Myocardial Ischemia
| Article | Year |
|---|---|
Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors.
Topics: Animals; Chloramphenicol; Cimetidine; Creatine Kinase; Cytochrome P-450 Enzyme Inhibitors; Cytochrom | 2004 |